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Massive Study Finds Coffee Drinkers Will Probably Outlive The Rest of Us : ScienceAlert

Based on an analysis of just under half a million records in the UK Biobank, people who drink two to three cups of coffee each day tend to live longer and exhibit less cardiovascular disease compared with those who abstain from the beverage.

While the research doesn’t claim drinking more coffee adds years to your life, it’s nevertheless an intriguing association that scientists are keen to investigate further. It’s also important to weigh the findings against previous studies linking brain shrinkage and an increased risk of dementia with a daily habit of six or more cups of coffee.

“In this large, observational study, ground, instant and decaffeinated coffee were associated with equivalent reductions in the incidence of cardiovascular disease and death from cardiovascular disease or any cause,” says electrophysiologist Peter Kistler, from the Baker Heart and Diabetes Institute in Australia.

“The results suggest that mild to moderate intake of ground, instant and decaffeinated coffee should be considered part of a healthy lifestyle.”

The UK Biobank is a large-scale database containing records on individuals’ genetics, health, and lifestyle. In this study, the sample provided an average of 12 and a half years’ worth of health and dietary information on 449,563 people with a median age of 58.

The participants were grouped according to their daily coffee consumption, and what type of coffee they usually drank – with just over 100,000 people reporting that they didn’t drink coffee at all. As part of the analysis, the researchers factored in the effects of age, sex, ethnicity, obesity, high blood pressure, diabetes, obstructive sleep apnoea, smoking status, and tea and alcohol consumption.

From there, Kistler and colleagues could compute differences in heart health outcomes and death from any cause for all coffee drinkers over the study time period, compared to those who didn’t drink coffee.

Drinking instant, ground and even decaffeinated coffee were all associated with a lower likelihood of death. Those who drank two or three cups of coffee a day had better odds of living longer than those who didn’t drink any.

Researchers can only guess what might be behind the relationship. If it is the coffee itself, a wide variety of potential compounds could be responsible.

Caffeine is the most well-known constituent in coffee, but the beverage contains more than 100 biologically active components,” says Kistler.

“It is likely that the non-caffeinated compounds were responsible for the positive relationships observed between coffee drinking, cardiovascular disease and survival.”

Digging deeper, the team found coffee consumption was also linked with the development of cardiovascular disease, with the lowest risk seen amongst those who consumed two to three cups a day.

There were slightly different findings for the risk of arrhythmia or an abnormal heart rhythm – here ground and instant coffee, but not decaffeinated, were linked to a lower likelihood of developing the condition. Once again, just a couple of cups each day seemed to be the sweet spot.

As a lot of previous research has shown, coffee is a complex substance that interacts with the body in a number of complex ways – ways that scientists are still trying to understand. That this study covered so many people over an extended period only adds weight to the link between coffee drinking and longevity.

However, there are some limitations to consider. The database records were predominantly Caucasian, making it harder to generalize the findings across a more ethnically diverse population. Coffee drinking was also self-reported rather than monitored, and the database doesn’t factor in changes in coffee consumption or coffee type over time.

For now, sip that morning brew guilt free – chances are it’s doing you some good.

“Our findings indicate that drinking modest amounts of coffee of all types should not be discouraged but can be enjoyed as a heart healthy behavior,” says Kistler.

The research has been published in the European Journal of Preventive Cardiology.

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The rest of Intel Arc’s A700-series GPU prices: A750 lands Oct. 12 below $300

Enlarge / Intel arrives at a crucial sub-$300 price for its medium-end GPU option. But will that bear out as a worthwhile price compared to its performance?

Intel

Intel’s highest-end graphics card lineup is approaching its retail launch, and that means we’re getting more answers to crucial market questions of prices, launch dates, performance, and availability. Today, Intel answered more of those A700-series GPU questions, and they’re paired with claims that every card in the Arc A700 series punches back at Nvidia’s 18-month-old RTX 3060.

After announcing a $329 price for its A770 GPU earlier this week, Intel clarified it would launch three A700 series products on October 12: The aforementioned Arc A770 for $329, which sports 8GB of GDDR6 memory; an additional Arc A770 Limited Edition for $349, which jumps up to 16GB of GDDR6 at slightly higher memory bandwidth and otherwise sports otherwise identical specs; and the slightly weaker A750 Limited Edition for $289.

Enlarge / A770 (16GB model) and A750 specs breakdown.

Intel

If you missed the memo on that sub-$300 GPU when it was announced, the A750 LE is essentially a binned version of the A770’s chipset with 87.5 percent of the shading units and ray tracing (RT) units turned on, along with an ever-so-slightly downclocked boost clock (2.05 GHz, compared to 2.1 GHz on both A770 models).

Intel previously confirmed that new purchases of Arc A700 series GPUs made by January 2023 would come with a bundle of downloadable games and software, including this year’s remake of Call of Duty: Modern Warfare II, Gotham Knights, and more.

Ahead of independent benchmarks, GPUs have a confusing “performance-per-dollar” metric

Enlarge / A refresher on Intel’s first-gen Arc GPU variety.

Intel

In a conference call with the press, Intel representatives declined to clarify initial shipment counts for its first three A700-series GPUs, other than to suggest low stock for the larger-memory A770 LE: “I suspect we’re going to sell out of that one very quickly,” Intel Graphics Fellow Tom Petersen told Ars. He was reluctant to clarify whether he expected early sellouts of Intel’s A700 GPUs, “We don’t know if we’re going to have a supply problem or a demand problem. I hope we have a demand problem.” He then confirmed that Intel plans to produce its own in-house GPU models over time, instead of cutting off “LE” production while demand might still exist.

Unfortunately, Intel compounded the GPUs’ availability question by not confirming which add-in board (AIB) partners would be part of the A700 series’ October rollout. Petersen kicked that can down the road by suggesting those third-party GPU manufacturers will make their own announcements, then mentioned an interest in expanding its list of Arc-powered AIBs.

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Kyle Shanahan confirms that Trey Lance is out for the rest of the year

USA TODAY Sports

In the aftermath of the broken ankle suffered by 49ers quarterback Trey Lance in Week Two, some uncertainty had emerged as to the question of whether Lance has a chance to play again this year.

On Wednesday, coach Kyle Shanahan told reporters that Lance will not return later in the regular season, or in the postseason (if the 49ers make it there).

“He’ll be out until next season,” Shanahan said.

It’s unclear whether Lance would have a chance to recover and be ready to go. If there would be, Shanahan doesn’t seem to be interested in pursuing that route.

So it’s now about getting Lance ready for 2023. Shanahan was asked about Lance’s spirits.

“He’s doing as good as you can,” Shanahan said. “Trey’s been great. A number of guys, we’ve all talked to him a bunch, and he’s trying to come to the game this week. I don’t think he’ll be able to, until the swelling goes down, but he’ll be back and a part of us sooner than later.”

Lance will presumably be part of the team next year; he’s under contract through 2024. But the pressure will be more significant than ever on Lance as he enters his third NFL season. It’s not his fault. The circumstances add pressure and expectations for which he didn’t bargain. From being the third pick to the 49ers giving up so much to get him to having Jimmy Garoppolo on the team in 2021 and 2022 to watching Garoppolo possibly play so well this year that the 49ers would perhaps bring him back next year, Lance has had something far different than the typical experience for a first-round quarterback.

Year three is often the up-or-out season for first-round signal-callers. Even if Lance’s grace period is extended, he’ll be approaching the end of it — without having done much to make anyone think he may be the long-term answer in San Francisco.

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Seattle Seahawks star safety Jamal Adams expected to miss rest of NFL season

Seattle Seahawks safety Jamal Adams is expected to miss the remainder of the NFL season after suffering an injury to his quadriceps tendon in the team’s opener, a source confirmed to ESPN’s Jeremy Fowler.

The Seahawks placed Adams on injured reserve on Thursday and signed defensive back Teez Tabor off the Atlanta Falcons’ practice squad to take his place on their 53-man roster.

Adams and the Seahawks believed the three-time Pro Bowl selection was in for a bounce-back campaign after a disappointing 2021 season in which he was held without a sack in 12 games. But any chance of that ended in the second quarter of Seattle’s 17-16 victory over the Denver Broncos on Monday night when Adams was carted off the field after he was hurt while blitzing former teammate Russell Wilson.

Coach Pete Carroll called it a “serious” injury postgame and said on his weekly radio show on Seattle Sports 710 AM on Tuesday morning that Adams would “have to get some work on that,” though he stopped short of declaring then that Adams’ season was over.

NFL Network first reported Thursday that Adams would have season-ending surgery.

Adams limped off the field in obvious pain, heavily favoring his left leg, after delivering pressure and a hit on Wilson that helped force a third-down incompletion. After being examined in the medical tent, he was helped onto an injury cart. Adams was visibly upset, at one point appearing to burst out in frustration, as he was driven into the locker room.

Carroll has said the injury is to Adams’ quadriceps tendon, which attaches the quad muscle to the top of the kneecap.

“The fact that he is such a heartthrob about the game of football, he loves playing and he just can’t deal with it right now about ‘how could this keep happening?'” Carroll said on his radio show. “It was good he had his mom and dad in the locker room really during the game when he was in there to kind of help him through it and all that, but it was really tough. So I hope everybody sends the love to him.”

Adams had three tackles and defended a pass before his injury. Josh Jones replaced him for the rest of the game. Seattle also has Ryan Neal as a safety option. Neal made four starts in 2020 while Adams was sidelined by a groin injury. Tabor, 26, played safety last season with the Chicago Bears under defensive coordinator Sean Desai, who’s now on Seattle’s defensive staff.

Adams missed only two games over his first three seasons with the New York Jets but then missed nine games over his first two seasons with the Seahawks — four in 2020 and the final five last season after he suffered another torn shoulder labrum that required surgery. Adams missed time early in training camp this summer after rebreaking the middle finger on his left hand, another injury he has dealt with in the past. He had finger surgeries in each of the past two offseasons.

Adams and the Seahawks were hoping that Seattle’s new defense — with its emphasis on split-safety looks — would put him in position for a bounce-back. During his stellar debut season in Seattle in 2020, Adams set the NFL record for sacks by a defensive back with 9.5, earning him his third straight Pro Bowl nod. But then came his zero-sack 2021 season, which ended after 12 games when he retore his shoulder labrum.

Speaking last week for the first time since his latest finger injury, Adams said Seattle’s new defense puts him “in position to make plays.”

“I’m back in my element, man,” he said. “I feel like I’m back playing defense.”

The Seahawks acquired Adams from the Jets in 2020 for a package that included first-round picks in 2021 and 2022. They signed him to a four-year, $70 million extension last summer that made him the NFL’s highest-paid safety at that time.

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Britain’s Queen Elizabeth II postpones important meeting after doctors advise her to rest

The 96-year-old monarch was scheduled to attend a virtual meeting of her Privy Council on Wednesday, a day after she appointed Liz Truss as the new UK Prime Minister. Truss is the 15th Prime Minister appointed by the Queen during her 70-year reign.

The Privy Council is a body formed of senior politicians who act as the Queen’s official advisers. During the gathering on Wednesday, Truss would have taken her oath and new cabinet ministers would have been sworn into their roles.

“After a full day yesterday, Her Majesty has this afternoon accepted doctors’ advice to rest. This means that the Privy Council meeting that had been due to take place this evening will be rearranged,” a Palace spokesman said.

A royal source said the meeting was virtual and the Queen hasn’t been to the hospital.

The Queen remains at Balmoral Castle, her Scottish country residence, where she received Truss and her predecessor Boris Johnson on Tuesday — the first time a prime minister has officially tendered their resignation or been appointed outside of Buckingham Palace during the Queen’s seven decades on the throne.

Buckingham Palace announced in advance that the Queen would not be making the 1,000-mile round trip from Scotland. A royal source told CNN the decision was to avoid any last-minute alternative arrangements in the event the Queen finds herself experiencing any episodic mobility issues.

Appointing a new prime minister is one of the Queen’s core ceremonial responsibilities as Head of State — with others being the State Opening of Parliament and the signing of parliamentary bills into law.

In May, the Queen missed the State Opening of Parliament for the first time in 59 years. The palace cited the monarch’s “episodic mobility problems” but declined to divulge further details citing patient confidentiality.

Instead, Princes Charles and William took center stage at the event, with the heir to the throne reading the government’s legislative agenda for the year ahead on his mother’s behalf.
The ongoing mobility issues, which the Queen has faced for nearly a year since a brief hospital stay last October, have also hampered other occasions including her Platinum Jubilee celebrations in June.

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Michael King Suffers Elbow Fracture, Expected To Miss Rest Of Season

Yankees reliever Michael King has a fracture in his throwing elbow, reports Joel Sherman of the New York Post (Twitter links). The team will know more after further testing tonight, but Sherman adds the club currently anticipates the injury will end his season. King departed tonight’s outing against the Orioles with elbow pain, and Bryan Hoch of MLB.com tweeted shortly after the game ended the Yankees were preparing to replace him on the roster.

Assuming further testing confirms the initial diagnosis and timetable, the Yankees will play the remainder of the season without one of the league’s best relievers. The 27-year-old has been an excellent multi-inning weapon for skipper Aaron Boone, working 51 frames across 34 outings. King owns a sparkling 2.29 ERA with the peripherals to match. He’s punched out an elite 33.2% of opposing hitters, induced ground-balls at an above-average 47% clip and only walked 8% of opponents.

The disappointing news will likely increase the front office’s urgency to add to the late-game mix before the August 2 trade deadline, although no one they acquire could reasonably be expected to replicate King’s production. Clay Holmes remains on hand as an elite weapon, but King had been a pivotal arm to bridge the gap between the starters and Holmes. He’d mostly assumed a role in which Chad Green has thrived for the past few seasons after the Yankees lost Green to Tommy John surgery in May.

Jonathan Loáisiga and Aroldis Chapman have been Boone’s two other primary high-leverage arms. Both hurlers have strong pre-2022 track records, but neither has been good this season. Loáisiga has a dreadful 7.45 ERA through 19 1/3 innings, while Chapman has an untenable 17.2% walk rate and a personal-low 24.7% strikeout percentage. Wandy Peralta has been a reliable ground-ball specialist from the left side, but the right-handed group prior to Holmes looks lackluster with Green and King out and Loáisiga struggling.

There are always a host of middle innings relievers available at the trade deadline, and general manager Brian Cashman and his staff figure to scour that market over the next ten days. Old friend David Robertson and Mychal Givens (Cubs), Michael Fulmer (Tigers) and Anthony Bass (Marlins) are among the shorter-term veterans who figure to be available, while players like Scott Barlow (Royals), Kyle Finnegan (Nationals) and Jorge López (Orioles) have longer windows of remaining club control.

As for King, it’s no doubt a crushing blow to see his breakout season likely come to a close early. He’d been a solid swing option last year, working to a 3.55 ERA through 63 1/3 frames, but this year’s emergence was on a different level. King will be eligible for arbitration for the first time after this season, and he’s under control through the 2025 campaign.



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We Discuss ‘Stray’ And The Most Anticipated Games For The Rest of 2022

We’re more than halfway through 2022, but for gamers, the best is yet to come. And that’s saying something because all things considered, it’s been a fantastic year for video games.

The expected hits— Horizon Forbidden West, Elden Ring, Kirby and the Forgotten Land—lived up to expectations. But there were also the hidden gems, like beat ‘em up Sifu and skateboarding extravaganza OlliOlliWorld. There were story-driven interactive games like The Quarry. There were nostalgia-fests like Teenage Mutant Ninja Turtles: Shredder’s Revenge. The sheer variety of bangers is impressive—so many genres, so many gameplay experiences, so little time. And the best part? There’s more in store for the next half of the year if those weren’t enough for you.

Here are our picks for the 10 most anticipated video games for the rest of 2022, including one—Stray—that launches this week. And these are just the ones we know about; there’s always a chance that an indie game will come along, surprise us, and exceed them all.

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China growth hopes rest on troubled local government financing vehicles

If the Chinese government is able to reach its economic growth target of 5.5 per cent this year, it will be due in part to retail investors such as Jane Song.

In May, Song invested Rmb200,000 ($29,600) in a fixed-income wealth management product issued by a local government financing vehicle in eastern Shandong province. A financial adviser in Shanghai, she was undeterred by the growing reluctance of bigger investors to back LGFVs, which play a vital role in funding infrastructure development across China.

“If the WMP defaults, the local government will have trouble accessing credit in future,” said Song, who expects to get 8.8 per cent interest on the “medium risk” product. “They are not going to let that happen.”

The scale of the challenge China faces in reaching its annual growth target was underlined on Friday by data showing that the economy expanded just 0.4 per cent year-on-year in the three months to June.

Hitting 5.5 per cent growth for the year will only be possible if LGFVs accelerate construction activity. But the local government vehicles are finding it difficult to borrow from banks and institutional bond investors, and are increasingly being forced to offer retail investors high interest rates to raise cash.

Tapping retail investors directly, some for as little as Rmb50,000 each, is a new departure for LGFVs. They have traditionally raised capital from institutions — mainly banks — or from rich individual investors acting through third parties such as trust firms and brokerages and with minimum investments set at Rmb1mn.

But Beijing’s crackdown on shadow banking over recent years has made it more difficult to access such individual investment. The outstanding value of infrastructure-backed trust products has dropped by almost half from a 2017 peak of Rmb3.2tn.

Last month, Limin Construction Development Group, an LGFV in Zoucheng city in Shandong, turned to social media platforms such as WeChat in its effort to raise Rmb200mn from retail investors.

It is promising 8.6 per cent interest — much more than it would pay if banks were willing to lend. The average annual interest rate charged by Chinese banks for business loans was 4.16 per cent in June.

Limin’s prospectus does not specify how the proceeds will be spent, other than saying they will help “replenish working capital”.

“You don’t need to know how exactly we are going to spend the money,” said a Limin executive. “We will pay you back on time and that’s all that matters.”

The executive, who asked not to be identified because he was not authorised to speak to foreign media, added the vehicle was close to reaching its fundraising target.

Similar appeals have been issued on social media by hundreds of LGFVs across the country, raising concerns that local governments that are already highly leveraged are amassing potentially explosive debt loads.

“This is another way for [local governments] to delay the inevitable,” said Andrew Collier, managing director of Orient Capital Research in Hong Kong. “This is the last gasp of a desperate economy trying to paper together its growth.”

Samuel Kwok, head of Asia-Pacific public finance at Fitch Ratings, said issuance of short-term, high-cost debt by many LGFVs in China’s economically weaker regions was a sign they were having refinancing issues.

“The ability to refinance is key to LGFVs, as they are supposed to finance the local economic development on behalf of the governments,” Kwok said.

Bond investors and other more traditional creditors have become more wary of LGFVs even as Beijing makes it a policy priority to support infrastructure projects and boost an economy hit hard by president Xi Jinping’s “zero-Covid” lockdowns.

LGFVs with credit ratings of AA or below raised only a net Rmb204bn from the bond market in the first half of this year, down 50 per cent from the same period in 2021, according to East Money Information, a financial data provider.

Multiple local banks, which across China are the biggest bond buyers, told the Financial Times they were shunning low-rated LGFV bonds. “We won’t go for LGFV bonds rated below AA+,” said an investment manager at a lender in the eastern city of Suzhou. “And there is a clear preference towards bonds issued by economically strong regions.”

Limin, the Zoucheng-based LGFV, reported Rmb2.9bn in cash at the end of last year, almost 80 per cent of which it could not access because it was pledged as margin deposit for bank creditors.

“If you have Rmb2.9bn worth of cash and are rushing to pay 9 per cent for Rmb200mn in private loans, it is about pretending you are solvent when you are not,” said Collier at Orient Capital.

Limin said it was “operating normally”.

Yang Xiaoyi, a government finance analyst at Beijing consultancy Mingshu Data Technology, said it was increasingly common for LGFVs to delay repayments of the principal they owe investors while making good on the annual interest owed — essentially turning their investments into perpetual bonds.

“You have to allow the investment to roll over indefinitely to avoid a default,” said Yang.

Regional authorities are aware of the risks. In an internal circular issued last month by Henan province’s finance bureau and seen by the FT, the regulator said it would ban local LGFVs from directly selling debt securities to individuals. The ban came after hundreds of investors invested in multiple platforms offering annual returns of 8.5 to 10 per cent.

“The practice,” the bureau said, “has severely disrupted economic and financial order and could easily lead to social instability.”

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Blazers rookie Shaedon Sharpe to miss rest of Summer League due to small labral tear in left shoulder

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Portland Trail Blazers rookie Shaedon Sharpe suffered a small labral tear in his left shoulder during their Summer League opener  Thursday against the Detroit Pistons and will be reevaluated in 10-14 days, the team announced Saturday. Sharpe had an MRI Friday, which confirmed the injury. With Summer League ending on Sunday, July 17, Sharpe will miss the remainder of the festivities in Vegas.

Sharpe suffered his injury only six minutes into Portland’s game against Detroit. He did not return in the first half, and his absence was announced in the second half. Teams almost always err on the side of caution when it comes to Summer League injuries because the games don’t count. In all likelihood, Sharpe will not be the only rookie to be ruled out before Summer League ends.

Sharpe was the No. 7 overall pick in the 2022 NBA Draft, but was among the more mysterious prospects available. A top recruit out of high school, Sharpe attended the University of Kentucky but didn’t actually play there after graduating high school early and initially planning to redshirt his freshman season before playing for the Wildcats next year. He was such a promising high school prospect that Portland felt comfortable picking him in the lottery regardless.

That would have made Summer League an excellent showcase for Sharpe, but he’ll have plenty of chances to prove himself on the court when the season begins in October. Neither he nor the Blazers have much to gain by pushing him to play injured now, so his Summer League is almost certainly over.

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Santana cancels 6 tour dates days after guitarist collapsed onstage from dehydration: ‘Just needs rest’

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Days after legendary guitarist Carlos Santana collapsed onstage in Michigan due to dehydration, the band is postponing their next six shows out of an “abundance of caution.” 

“Doctors have recommended that Mr. Santana gets rest to recuperate fully,” Santana’s manager Michael Vrionis said in a statement Friday. 

The guitarist and his band Santana delayed a Friday night show in Noblesville, Indiana and upcoming shows in Cincinnati, Ohio; Milwaukee, Wisconsin; Rogers, Arkansas; Dallas Texas; and Woodlands, Texas, will also need to be rescheduled, a release on his website said. 

“Carlos is doing well and is anxious to be back on stage soon. He just needs rest,” Vrionis added. “Santana profoundly regrets … these postponements of his upcoming performances; but, his health is our number one concern. He is looking forward to seeing all of his fans very soon.” 

CARLOS SANTANA’S WIFE SHARES UPDATE AFTER LEGENDARY GUITARIST COLLAPSES DURING CONCERT

Guitarist Carlos Santana of Santana performs on stage at North Island Credit Union Amphitheatre on June 17, 2022 in Chula Vista, California. (Photo by Daniel Knighton/Getty Images)
(Photo by Daniel Knighton/Getty Images)

The band, who is playing locations around the country for the “Miraculous Supernatural Tour” with Earth, Wind & Fire, also canceled a show last Wednesday. 

GUITAR LEGEND CARLOS SANTANA COLLAPSES ON STAGE DURING CONCERT IN MICHIGAN

The 74-year-old was diagnosed with exhaustion and dehydration after he collapsed 40 minutes into a set at an outdoor theater in Clarkston, Michigan Tuesday evening. 

The musician waved to fans as he was taken off the stage and hours later told people he was “good” and had just forgotten to eat and drink that day.

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Recording artist Carlos Santana autographs congas that he and his wife Cindy Blackman Santana donated to the Las Vegas Philharmonic while participating in the Philharmonic’s global edition of the orKIDStra music education program for a group of students at the Discovery Children’s Museum on October 29, 2019 in Las Vegas, Nevada.  (Photo by Ethan Miller/Getty Images)
(Photo by Ethan Miller/Getty Images)

His wife, Cindy Blackman, shared an update the next day, writing, “Please know that he’s resting and doing very well! He was diagnosed with heat exhaustion & dehydration … it was 100 degrees on stage and 114 under the lights so that coupled with not enough water is what caused the issue. He’ll be as good as new soon! Thank you again and we love you!”

The postponed shows run through July 16. The new concert dates will be announced by Live Nation soon, the release said. 

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 All shows from July 23 in Paso Robles, California through the end of the year are still confirmed, the statement said. 

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