Tag Archives: health and medical

Drug overdose deaths hit highest number ever recorded



CNN
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Drug overdose deaths rose by close to 30% in the United States in 2020, hitting the highest number ever recorded, the US Centers for Disease Control and Prevention reported Wednesday.

More than 93,000 people died from drug overdoses in 2020, according to provisional data released by the CDC’s National Center for Health Statistics. That’s a 29.4% increase from the 72,151 deaths projected for 2019.

“Overdose deaths from synthetic opioids (primarily fentanyl) and psychostimulants such as methamphetamine also increased in 2020 compared to 2019. Cocaine deaths also increased in 2020, as did deaths from natural and semi-synthetic opioids (such as prescription pain medication),” the NCHS said in a statement.

“This is the highest number of overdose deaths ever recorded in a 12-month period, and the largest increase since at least 1999,” Dr. Nora Volkow, director of the National Institute on Drug Abuse (NIDA), part of the National Institutes of Health, said in a statement.

“These data are chilling. The COVID-19 pandemic created a devastating collision of health crises in America,” added Volkow.

As in recent years, inappropriate use of opioids was behind most of the deaths. The NCHS reported that overdose deaths from opioids rose from 50,963 in 2019 to 69,710 in 2020.

“This has been an incredibly uncertain and stressful time for many people and we are seeing an increase in drug consumption, difficulty in accessing life-saving treatments for substance use disorders, and a tragic rise in overdose deaths,” Volkow said.

“As we continue to address both the COVID-19 pandemic and the opioid crisis, we must prioritize making treatment options more widely available to people with substance use disorders.”

Dr. Joshua Sharfstein, vice dean for public health practice at the Johns Hopkins Bloomberg School of Public Health and a former deputy commission at the US Food and Drug Administration, agreed the pandemic made an already serious crisis even worse.

“The pandemic had a lot to do with it,” Sharfstein told CNN.

“But as the pandemic recedes, we are still dealing with this overdose crisis.”

Overdoses from opioids have been steadily worsening in the US for decades. Some members of Congress have blamed the FDA for approving new synthetic opioids, and makers of some of the drugs – notably Oxycontin maker Purdue Pharma – have been prosecuted for their role in marketing them.

Last week, members of the Sackler family, who own Purdue, reached a $4.5 billion settlement with 15 states as part of legal actions dissolving the company.

Doctors have also been blamed for overprescribing opioids and addicting people to them in the first place.

Sharfstein said he thinks the FDA could and should do more to control over-prescribing of opioids.

“There are definitely actions that the clinical community can take to reduce the risk of people becoming addicted to opioids,” Sharfstein told CNN.

“The FDA oversight of medical and clinical practice is an area the agency acknowledges it needs to improve. The question of whether a particular drug should have been approved or not is fair to ask. But now the emphasis should be on the oversight of prescribing,” added Sharfstein.

“If you think about how the country has made progress on Covid since there was a clear national strategy that included goals and good data and evidence for critical projects – I think that kind of approach is important here. The same kind of urgency and strategy that has been applied to Covid could produce results over time.”

Sharfstein was pleased by the announcement Tuesday that President Joe Biden would nominate former West Virginia health commissioner Dr. Rahul Gupta to head the White House Office of National Drug Control Policy. If confirmed, Gupta would be the first physician to lead the office.

“Dr, Gupta is experienced at viewing the drug crisis as a health problem. He’ll follow the evidence where it takes him,” Sharfstein said.

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Indonesia Covid-19: Almost half of Jakarta’s population may have caught the virus, survey finds

Dita Alangkara/AP

A woman has her nasal swab samples collected during mass testing for Covid-19 in Bekasi on the outskirts of Jakarta, Indonesia, on June 29, 2021.



CNN
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Nearly half of Jakarta’s residents may have contracted Covid-19, according to a health survey – more than 12 times the number of cases officially recorded in the Indonesian capital at the time when the research was carried out.

The survey, published July 10, tested for coronavirus antibodies in the blood of about 5,000 people across the city from March 15-31. The results showed 44.5% of those tested had antibodies, indicating they had been infected with Covid-19.

The report was a collaboration between the Jakarta Provincial Health Office, the University of Indonesia’s Faculty of Public Health, the Eijkman Institute for Molecular Biology and staff from the US Centers for Disease Control and Prevention (CDC) based in Indonesia.

Jakarta has a population of about 10.6 million, government figures show. According to the researchers, as many as 4.7 million people may have been infected in the capital by March 31.

“Through this survey, we can estimate the proportion of Jakarta residents who have been infected by the SARS CoV-2 virus, whether identified by PCR tests or not,” said Widyastuti, head of Jakarta’s Provincial Health Office, in an online press conference on July 10, state-run news agency Antara reported.

According to Indonesian Health Ministry data, Jakarta had recorded more than 382,000 cases of Covid-19 on March 31, when the survey ended. By Tuesday, that number had shot up to 689,243.

This uptick in the capital comes as Indonesia – the world’s fourth most populous nation – faces a dire stage in its battle with the pandemic, recording tens of thousands of daily cases and up to 1,000 deaths a day nationwide in one of Asia’s worst outbreaks.

Hospitals across the country, notably on the island of Java – where Jakarta is located – have been pushed to the brink by the spread of the highly infectious Delta variant, with several cities including the capital placed under partial lockdown.

Dr. Pandu Riono, an epidemiologist from the University of Indonesia’s school of public health, said the survey found some people are at higher risk than others, Antara reported.

“People in densely populated areas are more susceptible to being infected with Covid-19,” he said. “The higher the body mass index, the more infected, in this case [those who are] overweight and obese. People with high blood sugar levels are also more at risk.”

The report also found the highest number of antibodies in the 30-49 age group and that infection rates were higher in women.

The results fall in line with health experts’ fears that Indonesia’s Covid-19 crisis may be more severe than official numbers suggest, with the country initially slow to test and contact trace. At first, authorities did not realize how quickly the virus had been spreading in this latest wave, Health Minister Budi Gunadi Sadikin previously told CNN.

Scientists have found it’s likely that people recovering from coronavirus have some immunity – but it’s not clear how strong it is or how long it lasts.

Herd immunity is the idea that a disease will stop spreading once enough of a population becomes immune, however, the researchers were wary of attributing the high percentage of antibodies found in their survey to herd immunity.

“In an open city like Jakarta – which has high intra- and inter-region mobility – it is hard to achieve herd immunity,” the researchers said.

Jakarta should instead focus on vaccinating residents to build immunity to the virus, they added.

Indonesia has fully vaccinated just 5.5% of its population, according to CNN’s Covid-19 vaccine tracker. In Jakarta, more than 1.95 million people – or about 18% of the population – have been fully vaccinated, according to Health Ministry data.

Indonesia has mostly relied on Sinovac in its national Covid-19 vaccination rollout that started in January. Concerns have been raised in recent weeks about the efficacy of the Chinese vaccine against more infectious variants after hundreds of health workers contracted the disease despite being vaccinated, with dozens hospitalized.

Health minister Budi said in a news briefing Friday that all health workers would receive a third shot of Moderna’s mRNA vaccine, Antara reported. The first shipments of the vaccine were sent to Indonesia from the United States over the weekend.

“We have agreed that the Moderna vaccine will be given as a third dose to provide maximum immunity to the existing viral mutations,” he said.

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US Covid-19: Fewer than half of states have reached the White House’s July 4th vaccine goal as the Delta variant threatens the nation’s progress



CNN
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Twenty states have reached the Biden administration’s goal to partially vaccinate 70% of American adults by the Fourth of July as the Delta variant spreads and people gather for holiday celebrations across the country.

White House officials acknowledged last month that they would fall short of their goal, which was set in early May when the US was vaccinating people at a much faster pace than it is now.

The US reached its highest vaccination rate in mid-April when the seven-day average of doses administered daily topped 3.3 million. At that time, 1.8 million new people became fully vaccinated each day.

But that rate was not sustained, dropping to a seven-day average of 1,121,064 doses given per day as of Saturday. About 685,472 people are becoming fully vaccinated daily.

However, the administration did come close to its goal of vaccinating 160 million adults by the holiday – 157 million adults were fully vaccinated as of Saturday, federal data shows.

Health experts have been sounding the alarm on the risk low vaccination rates pose in some areas as the Delta variant of the coronavirus is now detected in all 50 US states and Washington, DC.

The Delta variant, which is highly contagious and causes even more severe illness, has been spreading so rapidly in some areas that officials brought back their mask guidance even if people are fully vaccinated.

Health officials in Los Angeles County, suggested last week that people in the county should wear masks while in public indoor spaces, regardless of their vaccination status.

After California relaxed most of its Covid-19 restrictions on June 15, the state’s Covid-19 test positivity rate doubled from 0.7% at the time to 1.5% on July 2, state health data shows. The Delta variant represents 36% of all new Covid-19 cases in California, and that number is expected to rise, a state health officer said Friday.

Health experts and studies have said the Moderna, Pfizer/BioNTech and Johnson & Johnson vaccines are highly effective in protecting people from severe illness and hospitalizations related to Covid-19 and some of its dangerous variants.

Yet Barbara Ferrer, who heads Los Angeles County’s Public Health Department, told CNN Saturday the county’s new mask guidance is an extra precaution against the rise of Covid-19 cases there.

“There are lots of settings where even though we know that the vaccines provide powerful protection to those who are vaccinated, the slight risk that a vaccinated person could shed enough virus to infect somebody else, coupled with just creating less and less risk in those settings where there are many unvaccinated people, makes it a prudent tool that I think has its place in this full reopening that we’ve done in L.A. County,” Ferrer said.

She added that the county is not requiring people to wear masks.

“We just made a strong recommendation, if you’re indoors, in a setting where you don’t know everybody else’s vaccination status … it is best at this point to prevent another surge here in L.A. County by having everyone in those settings, where it could be crowded and you’re indoors, often with poor ventilation, to keep those face coverings on,” she said.

California is one of 19 states to have fully vaccinated more than half its population. The other 18 are: Colorado, Connecticut, Delaware, Hawaii, Maine, Maryland, Massachusetts, Minnesota, New Hampshire, New Jersey, New Mexico, New York, Oregon, Pennsylvania, Rhode Island, Vermont, Virginia and Washington state, as well as Washington, D.C.

Dr. Megan Ranney, an emergency physician at Brown University and CNN medical analyst, said Saturday that full approval of vaccines from the US Food and Drug Administration will help get more people vaccinated.

“I think that getting full approval will make a big difference. It will overcome that hesitancy or lack of confidence of a segment of our population,” she said.

Moderna and Pfizer/BioNTech have begun their applications for full approval from the FDA. Johnson & Johnson has said it intends to file a Biologics License Application, but had not yet done so as of Friday.

Pfizer and Moderna requested priority review, which asks the FDA to take action within six months, compared to the 10 months under standard review. Goal dates have not yet been announced.

“I wish the FDA would move faster,” Ranney said, referring to the approval process. “Full FDA approval process normally does takes months, but they’ve already looked at the preliminary data. It’s not that much more.”

A recent Kaiser Family Foundation survey shows 31% of adults who have yet to get vaccinated would be more likely to get a vaccine that is fully approved by the FDA. About 20% of adults who have not been vaccinated said it’s because they believe the vaccine is too new.

Dr. Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases, said during a White House Covid-19 briefing on Thursday it would be “most unusual” for the FDA to refuse full approval for coronavirus vaccines being used under emergency use authorization.

“You never want to get ahead of the FDA, but it would really be a most unusual situation not to see this … get full approval,” Fauci said. “I believe it’s going to happen.”

The number of people traveling by air hit a new pandemic-era record Friday as people are on the move for the Fourth of July weekend.

The Transportation Security Administration said it screened 2,196,411 people at airports across the country, the highest number since the start of the pandemic.

According to the TSA, that number is higher than the same day in 2019 before the pandemic, when the TSA screened 2,184,253 passengers.

AAA anticipates 47.7 million people will travel by road and air from July 1 to July 5, a 40% increase over Independence Day travel last year and the second-highest travel volume on record.

CNN’s Nadia Kounang, Pete Muntean, Deidre McPhillips, Jamie Gumbrecht, Cheri Mossburg, Natasha Chen, Kevin Conlon, Deanna Hackney contributed to this report.



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