Tag Archives: health and medical

Science

A 319-million-year-old brain has been discovered. It could be the oldest of its kind

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CNN
 — 

A scan of the skull of a 319-million-year-old fossilized fish has led to the discovery of the oldest example of a well-preserved vertebrate brain, shining a new light on the early evolution of bony fish.

The fossil of the skull belonging to the extinct Coccocephalus wildi was found in a coal mine in England more than a century ago, according to researchers of the study published in the journal Nature on Wednesday.

The fossil is the only known specimen of the fish species so scientists from the University of Michigan in the US and the University of Birmingham in the UK used the nondestructive imaging technique of computed tomography (CT) scanning to look inside its skull and examine its internal bodily structure.

Upon doing so, came a surprise. The CT image showed an “unidentified blob,” a University of Michigan press release said.

The distinct, 3D object had a clearly defined structure with features found in vertebrate brains: It was bilaterally symmetrical, contained hollow spaces similar in appearance to ventricles and had extending filaments that resembled cranial nerves.

“This is such an exciting and unanticipated find,” study coauthor Sam Giles, a vertebrate paleontologist and senior research fellow at the University of Birmingham, told CNN Thursday, adding that they had “no idea” there was a brain inside when they decided to study the skull.

“It was so unexpected that it took us a while to be certain that it actually was a brain. Aside from being just a preservational curiosity, the anatomy of the brain in this fossil has big implications for our understanding of brain evolution in fishes,” she added.

C. wildi was an early ray-finned fish – possessing a backbone and fins supported by bony rods called “rays” – that is thought to have been 6 to 8 inches long, swum in an estuary, and ate small aquatic animals and aquatic insects, according to the researchers.

The brains of living ray-finned fish display structural features not seen in other vertebrates, most notably a forebrain consisting of neural tissue that folds outward, according to the study. In other vertebrates, this neural tissue folds inward.

C. wildi lacks this hallmark feature of ray-finned fish, with the configuration of a part of its forebrain called the “telencephalon” more closely resembling that of other vertebrates, such as amphibians, birds, reptiles and mammals, according to the study authors.

“This indicates that the telencephalon configuration seen in living ray-finned fishes must have emerged much later than previously thought,” lead study author Rodrigo Tinoco Figueroa, a doctoral student at the University of Michigan’s Museum of Paleontology, said.

He added that “our knowledge on the evolution of the vertebrate brain is mostly restricted to what we know from living species,” but “this fossil helps us fill important gaps in the knowledge, that could only be obtained from exceptional fossils like this.”

Unlike hard bones and teeth, scientists rarely find brain tissue – which is soft – preserved in vertebrate fossils, according to the researchers.

However, the study noted that C. wildi’s brain was “exceptionally” well preserved. While there are invertebrate brains up to 500 million years old that have been found, they are all flattened, said Giles, who added that this vertebrate brain is “the oldest three-dimensional fossil brain of anything we know.”

The skull was found in layers of soapstone. Low oxygen concentration, rapid burial by fine-grained sediment, and a very compact and protective braincase played key roles in preserving the brain of the fish, according to Figueroa.

The braincase created a chemical micro-environment around the enclosed brain that could have helped to replace its soft tissue with dense mineral that maintained the fine details of the brain’s 3D structures.

Giles said: “The next steps are to figure out exactly how such delicate features as the brain can be preserved for hundreds of millions of years, and look for more fossils that also preserve the brain.”

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Health

Complications during pregnancy linked to a higher risk of heart disease, study finds

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CNN
 — 

Five major pregnancy complications are strong lifelong risk factors for ischemic heart disease, a new study finds, with the greatest risk coming in the decade after delivery.

Ischemic heart disease refers to heart problems, including heart attack, caused by narrowed or dysfunctional blood vessels that reduce blood and oxygen flow to the heart.

Gestational diabetes and preeclampsia increased the risk of ischemic heart disease in the study by 54% and 30%, respectively, while other high blood pressure disorders during pregnancy doubled the risk. Delivering a baby early – before 37 weeks – or delivering a baby with a low birth weight were associated with a 72% and 10% increased risk, respectively.

The study, published in Wednesday in the BMJ, followed a cohort of more than 2 million women in Sweden with no history of heart disease who gave birth to single live infants between 1973 and 2015.

Roughly 30% of the women had at least one adverse pregnancy outcome. Those who had multiple adverse outcomes – whether in the same or different pregnancies – showed further increased risk of ischemic heart disease.

“These pregnancy outcomes are early signals for future risk of heart disease and can help identify high-risk women earlier and enable earlier interventions to improve their long-term outcomes and help prevent the development of heart disease in these women,” said Dr. Casey Crump, an author of the study and professor of family medicine at the Icahn School of Medicine at Mount Sinai.

Heart disease is the leading cause of death among women in the United States and accounts for 1 in 5 female deaths, according to the US Centers for Disease Control and Prevention. This research adds to mounting evidence that pregnancy provides important information about a woman’s cardiovascular health.

“What happens to a woman during pregnancy is almost like a stress test or a marker for her future cardiovascular risk after pregnancy. And unfortunately, a lot of women don’t get told this by anybody,” said CNN Medical Correspondent Dr. Tara Narula, an associate professor of cardiology and the associate director of the Women’s Heart Program at Lenox Hill Hospital. She was not involved in the new study.

Although it’s not completely clear why, experts say the normal changes that occur during pregnancy may unmask underlying health issues in some women with certain risk factors.

Experiencing an adverse pregnancy outcome – even temporarily – could result in changes to blood vessels and the heart that may persist or progress after delivery, increasing a woman’s risk for cardiovascular disease.

This heightened risk is a particular concern for women in the US, experts say, where the maternal mortality rate is several times higher than in other high-income countries.

“There’s been a change in the birthing population. US women are getting pregnant at a later age, and they have already accrued maybe one or two cardiovascular risk factors. Perhaps there are other stressors in life – depression, stress, isolation, obesity – lots of different things that are impacting women in the US,” said Dr. Garima Sharma, associate professor of cardiology and director of the Cardio-Obstetrics Program at Johns Hopkins University School of Medicine, who also was not involved in the new study.

Pregnancy complications are carefully monitored during pregnancy, but there is little evaluation of and education about the effects on cardiovascular health after delivery for women, experts say.

“And so they have their delivery, they’ve had maybe preeclampsia or gestational diabetes, and nobody really follows up with them. They are not told that, in fact, they are at increased risk,” Narula said.

Gestational diabetes is a marker not only for increased risk of diabetes but also for general cardiovascular disease. Preeclampsia and eclampsia are markers for hypertension risk as well as general cardiovascular risks.

Narula, a cardiologist who specializes in caring for women, regularly considers adverse pregnancy outcomes when evaluating patients and emphasizes the continued need for this.

“The classic risk calculator that we use doesn’t have anything in there for pregnancy complications, but you know, it should for women, and hopefully someday, they will start to take that into account,” she said.

The American Heart Association recommends that all health care professionals take a detailed history of pregnancy complications when assessing a woman’s heart disease risk, but this is not consistently done in clinical practice, especially in primary care, where most women are seen, Crump says.

“Raising awareness of these findings among physicians as well as women hopefully will enable more of these women to be screened early and hopefully improve their long-term outcomes,” he said.

Roughly 1 in 3 women will have an adverse pregnancy outcome. Experts say that improving your health before getting pregnant can help avoid these issues.

“Reducing your risk should start preconception, and so getting your body and yourself into the healthiest state possible before you ever even get pregnant is really the first step,” Narula said.

This includes achieving and maintaining a healthy body weight with a good diet and regular exercise, controlling high blood pressure and diabetes, quitting smoking and managing stress.

Taking action after pregnancy is equally important, as research has estimated that only 30% to 80% of women have a postpartum checkup 6 to 8 weeks after delivery.

“Making sure that these women actually are appropriately followed after their delivery and that there is a warm handoff between [obstetrics] and [maternal-fetal medicine] to their primary care doctors or preventive cardiologists who can then talk about optimizing cardiovascular risks and reduction of these risk factors post-pregnancy in the postpartum time frame is crucial,” Sharma said.

Experts hope that increased patient and provider awareness of the connection between pregnancy and heart health will keep birth from being a cause of death.

“Cardiovascular disease is preventable. It’s a leading cause of maternal mortality, but it doesn’t have to be. If we do a better job at screening patients before they get pregnant, if we do a better job of treating them during pregnancy and postpartum, we can improve women’s outcomes,” Narula said. “It’s a tragedy to bring a new life into the world, and then the mother suffers some horrible complication and/or death that could have been prevented.”

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World

Hong Kong is criminalizing CBD as a ‘dangerous drug’ alongside heroin

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Hong Kong
CNN
 — 

Two years ago, cannabidiol was booming in Hong Kong. The compound, known as CBD, was popping up in cafes, restaurants and stores, with businesses eager to join an exciting new market already well-established in countries around the world.

That all came to an end on Wednesday, when CBD was criminalized in the city and declared a “dangerous drug” on the same level as heroin and fentanyl.

CBD is a chemical found in hemp and marijuana plants. It’s non-psychoactive, meaning it won’t get you high; instead, CBD is often marketed for everything from helping to relieve pain and inflammation to reducing stress and anxiety.

It has surged in global popularity in recent years, with brands adding it to shampoos, drinks, body oils, gummy bears and dog treats. In the United States and Europe, you might find it sold in coffee shops and farmers’ markets, mom-and-pop and high-end department stores, and even drugstore chain CVS.

But last June, draft legislation banning CBD was introduced to Hong Kong lawmakers, and went into effect February 1.

Under the new legislation, possession and consumption of any amount of CBD is punishable by seven years in prison and a fine of 1 million Hong Kong dollars ($127,607). Manufacturing, importing or exporting CBD is punishable by life imprisonment.

Even travelers could face penalties, with the government warning people not to risk “buying these products or bringing them back to Hong Kong.”

The same penalties and conditions apply for cannabis, also known as marijuana.

The ban has forced CBD-focused businesses to close, while other brands have had to roll back or get rid of CBD products.

“It’s a shame because there’s a missed opportunity for sure,” said Luke Yardley, founder of Yardley Brothers Craft Brewery, which had previously sold four products containing CBD – a lager and three nonalcoholic drinks. “I think that anything that you can’t get intoxicated from, and helps you to relax, is probably a good thing.”

The health benefits and risks of CBD have long been debated. In the US, most CBD products are not regulated by the Food and Drug Administration (FDA), which means that people can purchase items off the shelf.

Some research has found that the compound can ease pain and may be useful for those who have trouble sleeping. The FDA has approved one drug with CBD to treat rare, severe forms of epilepsy.

But concerns have also been raised, with some experts saying there isn’t enough scientific research into how CBD works or its potential effects.

In January, the FDA announced CBD products will require a new regulatory pathway in the US, saying: “We have not found adequate evidence to determine how much CBD can be consumed, and for how long, before causing harm.”

In Hong Kong, which has strict cannabis laws, the government’s concern revolves around the possible presence of its sister compound THC (tetrahydrocannabinol) in CBD products. THC is also found in cannabis plants and is responsible for the “high.”

In the US and Europe, CBD products can carry up to 0.3% – a trace amount – of THC, but even that is not acceptable in Hong Kong. And while CBD products could avoid this trace amount by using a pure form of CBD, most manufacturers mix other compounds for higher potency.

From 2019 to early 2022, Hong Kong authorities launched nearly 120 “operations” seizing and testing CBD products from restaurants and shops to warehouses, Secretary for Security Tang Ping-keung said last year. He added that more than 3,800 products were found to contain THC, though did not give further detail on the proportion or percentage of THC in those products.

In a written response to questions raised in the Legislative Council, Tang suggested the government’s traditionally tough stance on THC should be applied to CBD “to protect public heath.”

“We have adopted ‘zero tolerance’ towards drugs and we understand that it is a matter of public concern,” he said. “Therefore, the government plans to control CBD.”

The Action Committee Against Narcotics, a group of representatives from “the fields of social work, education, medical and community service” that advises the government on anti-drug policy, said in a statement last November that it supported the CBD ban and the government’s goal of “a drug-free Hong Kong.”

Many businesses began bracing themselves for regulatory changes in 2022, ahead of the government’s official announcement this January.

Yardley Brothers Craft Brewery stopped making its CBD beverages late last year in anticipation of the ban, and all its leftover products had sold out by December, said Yardley.

He said the CBD drinks had been “very popular,” amounting to roughly 8% of the business, as they offered adults a nonalcoholic option to enjoy when out with friends. At some bars, regulars “come in every weekend for a glass of CBD lemonade,” he said.

Now “there’s less choice for consumers in Hong Kong. That’s not necessarily a step in the right direction,” he said.

Some companies have been forced to shut down completely.

Med Chef, a restaurant that opened in 2021, once boasted of offering Hong Kong’s “first full menu of CBD-infused cocktails, appetizers and entrees.” In a news release during its launch, the restaurant founder emphasized the health and wellness benefits of CBD.

But by early November 2022, it had closed its doors. “We have worked hard in the past to present CBD in its most acceptable form and integrate our food and beverage concepts,” the restaurant wrote in a farewell post on Instagram. “It’s a pity that things didn’t go the way we hoped. Under the latest policies of those in power, we ultimately aren’t able to continue forward with everyone.”

Hong Kong’s first CBD cafe, Found, had also made headlines when it opened in 2020. It sold a variety of CBD products including infused coffee and beers, oils to help sleep, powder to sprinkle into food and pet products to help ease stiff joints.

It closed at the end of September 2022, telling patrons on Instagram that their positive feedback had shown that “CBD could help to cope with the stresses of daily life.”

“Sadly, in spite of the demonstrable positive impact, it has now become apparent that the Hong Kong government intends to adopt new legislation to prohibit the sale and possession of CBD,” it wrote.

Yardley said the government’s concerns about THC were valid – but argued they could have implemented better regulations, such as requiring certifications or standards of safety around CBD samples.

“It’s quite an extreme response to just fully ban it,” he said.

And while the brewery will continue operating, with plans for alternative nonalcoholic beverages to fill the gap, Yardley hopes CBD will be back on the menu. “I hope for the future that it might become legal again,” he said.

This story has been updated to include details of the draft legislation and its introduction.



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US

Minnesota governor signs bill codifying ‘fundamental right’ to abortion into law

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CNN
 — 

Minnesota’s Democratic Gov. Tim Walz signed a bill into law Tuesday that enshrines the “fundamental right” to access abortion in the state.

Abortion is already legal in Minnesota, but in the aftermath of the US Supreme Court overturning Roe v. Wade, the Protect Reproductive Options Act goes a step further by outlining that every person has the fundamental right to make “autonomous decisions” about their own reproductive health as well as the right to refuse reproductive health care.

“This is very simple, very right to the point,” Walz said Tuesday on “CNN Tonight.” “We trust women in Minnesota, and that’s not what came out of the [Supreme Court’s] decision, so I think it’s critically important that we build a fire wall.”

With the passage of the bill, Minnesota is now the first state to codify abortion via legislative action since Roe v. Wade was reversed, the office of the bill’s lead author in Minnesota’s state Senate, told CNN.

“Last November, Minnesotans spoke loud and clear: They want their reproductive rights protected – not stripped away,” Walz said in a news release. “Today, we are delivering on our promise to put up a firewall against efforts to reverse reproductive freedom. No matter who sits on the Minnesota Supreme Court, this legislation will ensure Minnesotans have access to reproductive health care for generations to come. Here in Minnesota, your access to reproductive health care and your freedom to make your own health care decisions are preserved and protected.”

The bill states that local government cannot restrict a person’s ability to exercise the “fundamental right” to reproductive freedom. It also clarifies that this right extends to accessing contraception, sterilization, family planning, fertility services and counseling regarding reproductive health care.

“The Pro Act also goes beyond just granting those rights to abortion, it really says all reproductive healthcare decisions aren’t our business, including access to contraception, including access to really anything that is related to personal and private decisions about your reproductive life,” Megan Peterson, the executive director of pro-abortion rights campaign UnRestrict Minnesota, told CNN following Walz’s signing of the bill.

In a letter to Walz ahead of the signing, Republican legislature leaders argued that the bill went too far and urged the governor to veto what they called “an extreme law.”

“As the PRO Act was being rushed through the legislature, Republicans offered reasonable amendments with guardrails to protect women and children,” state Senate Minority Leader Mark Johnson and House Minority Leader Lisa Demuth wrote, “Sadly, each of these amendments were struck down by a Democrat majority.”

In 1995, the Minnesota Supreme Court ruled in Doe v. Gomez that abortion was a fundamental right protected under the state’s constitution. The Protect Reproductive Options Act ensures that even in the event of a new state Supreme Court reversing the ruling, the right to abortion will be protected under state law.

“By passing this law, Minnesotans will have a second layer of protection for their existing reproductive rights. A future Minnesota Supreme Court could overturn Doe v. Gomez, but with the PRO Act now in State law, Minnesotans will still have a right to Reproductive healthcare,” Luke Bishop, a spokesperson for Democratic State Sen. Jennifer McEwen, the bill’s author in the Senate, told CNN over email.

Following the governor’s signature of the bill, the White House applauded Minnesota’s efforts, pointing to the popular support for women’s rights to make their own health care decisions.

“Americans overwhelmingly support a woman’s right to make her own health care decisions, as so clearly demonstrated last fall when voters turned out to defend access to abortion – including for ballot initiatives in California, Kansas, Kentucky, Michigan, Montana, and Vermont,” White House press secretary Karine Jean-Pierre said in a statement.

“While Congressional Republicans continue their support for extreme policies including a national abortion ban, the President and Vice President are calling on Congress to restore the protections of Roe in federal law,” she wrote. “Until then, the Biden-Harris Administration will continue its work to protect access to abortion and support state leaders in defending women’s reproductive rights.”

This story has been updated with additional information.

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Health

EzriCare eye drops: CDC advises against use as it investigates dozens of infections and one death in 11 states

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CNN
 — 

The US Centers for Disease Control and Prevention is urging health care providers and consumers to stop using EzriCare Artificial Tears as it conducts an investigation into at least 50 infections in 11 states that have led to instances of permanent vision loss, hospitalization and one death.

Most of the people with these infections reported using artificial tears, and EzriCare was the most common brand, the agency says. These eye drops are preservative-free, meaning they don’t have ingredients to prevent bacterial growth.

Testing of open EzriCare bottles identified Pseudomonas aeruginosa bacteria that were resistant to carbapenem antibiotics as well as the antibiotics ceftazidime and cefepime. Testing of unopened bottles is ongoing, the CDC says.

“CDC recommends that clinicians and patients immediately discontinue the use of EzriCare Artificial Tears until the epidemiological investigation and laboratory analyses are complete,” the agency says.

New Jersey-based EzriCare says in a statement dated January 24 that it has not received any consumer complaints or adverse event reports.

“We have not been asked to conduct a recall. EzriCare does not manufacture the Lubricant Eye Drops,” the statement says.

“Nevertheless, and in an abundance of caution, EzriCare recommends that during this evolving situation you discontinue use of any portions of EzriCare Artificial Tears Lubricant Eye Drops you may have until we can discover more details about any potential safety concerns.”

Pseudomonas bacteria are common in the environment, such as in soil and water. Pseudomonas aeruginosa is usually spread in health care settings, the CDC says, and is increasingly difficult to treat because of antibiotic resistance. It caused more than 32,000 infections in hospitalized patients and about 2,700 deaths in the US in 2017.

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Health

Ultraprocessed foods linked to ovarian and other cancer deaths, study finds

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CNN
 — 

Eating more ultraprocessed foods raises the risk of developing and dying from cancer, especially ovarian cancer, according to a new study of over 197,000 people in the United Kingdom, over half of whom were women.

Overly processed foods include prepackaged soups, sauces, frozen pizza and ready-to-eat meals, as well as hot dogs, sausages, french fries, sodas, store-bought cookies, cakes, candies, doughnuts, ice cream and many more.

“Ultra-processed foods are produced with industrially derived ingredients and often use food additives to adjust colour, flavour, consistency, texture, or extend shelf life,” said first author Dr. Kiara Chang, a National Institute for Health and Care Research fellow at Imperial College London’s School of Public Health, in a statement.

“Our bodies may not react the same way to these ultra-processed ingredients and additives as they do to fresh and nutritious minimally processed foods,” Chang said.

However, people who eat more ultra-processed foods also tend to “drink more fizzy drinks and less tea and coffee, as well as less vegetables and other foods associated with a healthy dietary pattern,” said Duane Mellor, a registered dietitian and senior teaching fellow at Aston Medical School in Birmingham, UK, in an email.

“This could mean that it may not be an effect specifically of the ultra-processed foods themselves, but instead reflect the impact of a lower intake of healthier food,” said Mellor, who was not involved in the study.

The study, published Tuesday in the journal eClinicalMedicine, looked at the association between eating ultraprocessed foods and 34 different types of cancer over a 10-year period.

Researchers examined information on the eating habits of 197,426 people who were part of the UK Biobank, a large biomedical database and research resource that followed residents from 2006 to 2010.

The amount of ultraprocessed foods consumed by people in the study ranged from a low of 9.1% to a high of 41.4% of their diet, the study found.

Eating patterns were then compared with medical records that listed both diagnoses and deaths from cancer.

Each 10% increase in ultraprocessed food consumption was associated with a 2% increase in developing any cancer, and a 19% increased risk for being diagnosed with ovarian cancer, according to a statement issued by Imperial College London.

Deaths from cancers also increased, the study found. For each additional 10% increase in ultraprocessed food consumption, the risk of dying from any cancer increased by 6%, while the risk of dying from ovarian cancer rose by 30%, according to the statement.

“These associations persisted after adjustment for a range of socio-demographic, smoking status, physical activity, and key dietary factors,” the authors wrote.

When it comes to death from cancer among women, ovarian cancer is ranked fifth, “accounting for more deaths than any other cancer of the female reproductive system,” noted the American Cancer Society.

“The findings add to previous studies showing an association between a greater proportion of ultra-processed foods (UPFs) in the diet and a higher risk of obesity, heart attacks, stroke, and type 2 diabetes,” said Simon Steenson, a nutrition scientist at the British Nutrition Foundation, a charity partially supported by food producers and manufacturers. Steenson was not involved in the new study.

“However, an important limitation of these previous studies and the new analysis published today is that the findings are observational and so do not provide evidence of a clear causal link between UPFs and cancer, or the risk of other diseases,” Steenson said in an email.

People who ate the most ultraprocessed foods “were younger and less likely to have a family history of cancer,” Chang and her colleagues wrote.

High consumers of ultraprocessed foods were less likely to do physical activity and more likely to be classified as obese. These people were also likely to have lower household incomes and education and live in the most underprivileged communities, the study found.

“This study adds to the growing evidence that ultra-processed foods are likely to negatively impact our health including our risk for cancer,” said Dr. Eszter Vamos, the study’s lead author and a clinical senior lecturer at Imperial College London’s School of Public Health in a statement.

This latest research is not the first to show an association between a high intake of ultraprocessed foods and cancer.

A 2022 study examined the diets of over 200,000 men and women in the United States for up to 28 years and found a link between ultraprocessed foods and colorectal cancer — the third most diagnosed cancer in the United States — in men, but not women.

And there are “literally hundreds of studies (that) link ultraprocessed foods to obesity, cancer, cardiovascular disease, and overall mortality,” Marion Nestle, the Paulette Goddard professor emerita of nutrition, food studies and public health at New York University told CNN previously.

While the new UK-based study cannot prove causation, only an association, “other available evidence shows that reducing ultra-processed foods in our diet could provide important health benefits,” Vamos said.

“Further research is needed to confirm these findings and understand the best public health strategies to reduce the widespread presence and harms of ultra-processed foods in our diet,” she added.

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Health

Adult drug use rose during pandemic, but dropped dramatically in youth, study says

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CNN
 — 

Use of marijuana and other substances dropped in teenagers during the first year of the pandemic, according to a new study.

But adults’ use of cannabis, illegal drugs and alcohol, including binge drinking, either stayed the same or increased compared to the two years before Covid-19.

“Substance use decreased between 2019 and 2020 among those aged 13 to 20 years,” wrote first author Dr. Wilson Compton, deputy director of the National Institute on Drug Abuse.

However, “consistent declines were not seen in older persons other than tobacco use reductions, and cannabis use increased among adults ages 25 years and older,” he and his coauthors wrote.

The study analyzed data from the Population Assessment of Tobacco and Health Study, which follows tobacco and other substance use over time among 49,000 US youths and adults.

“A particular strength of this study was the longitudinal design,” said Joseph Palamar, an associate professor of population health at NYU Grossman School of Medicine, who was not involved in the study.

“This design allows us to look at changes among the same people over time as opposed to other national studies which compare different groups of people across time,” he said.

Substance abuse dropped in teenagers between ages 13 and 17, according to the study published Tuesday in the journal JAMA Network Open.

Cannabis use among teenagers ages 13 and 15 dropped by 3.4 percentage points in 2020 compared to 2018 and 2019, while tobacco use declined by about 4 points, the study found. The use of other illegal or misused prescription drugs also fell 2.5 percentage points in this age group.

Use of marijuana in teens ages 16 and 17 dropped 7.3 percentage points in 2020 compared to 2018 and 2019. Tobacco use fell by over 10 points and misuse of drugs sank by nearly 3 percentage points. Binge drinking dipped by 1.6 percentage points across the age group.

“I think availability plays a big part,” Palamar said. “If high schoolers are separated from their friends for a long time and stuck inside, they’ll likely have decreased access to drugs.

“Even if a teen successfully obtained weed, this doesn’t mean he or she had somewhere away from parents to smoke it if the whole family was on lockdown,” he added.

The use of alcohol increased by over five percentage points (from 60.2% to 65.2%) among adults ages 21 to 24 years old in 2020 compared to the previous two years. Binge drinking, however, fell by 2.2 points.

Tobacco use fell by about 8 percentage points, but use of marijuana and other illegal or prescription drugs did not change significantly in this age group, according to the study.

Use of marijuana increased slightly in adults 25 and up, by 1.2 percentage points. Declines in other substance abuse in this age group were not significant, the study authors said.

Tobacco use fell for all adults, the study found. The number of young adults ages 18 to 20 smoking tobacco dropped by just over 15 percentage points in 2020 compared to 2018 and 2019. Smoking also declined by about 8 points in adults ages 21 and up over the same period.

However, a drop in drug use during the early days of Covid did not mean the reduction continued as the pandemic wore on, said Palamar, who has been studying drug availability during that period.

“Decreases in use during the early months of Covid are meaningful, but we need to keep in mind that use of some drugs rebounded,” Palamar said. “For example, we found that seizures of marijuana and methamphetamine decreased after the start of Covid, and then rebounded to a much higher rate later in the year.”

A separate survey of people ages 19 to 30 found they were using marijuana and hallucinogens at high rates in 2021. The Monitoring the Future Study, published in 2022, found 11% of people in this age group used marijuana on a daily basis in 2021, while 43% said they had used it in the past year.

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Health

Infant screen time could impact academic success, study says

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CNN
 — 

Letting infants watch tablets and TV may be impairing their academic achievement and emotional well-being later on, according to a new study.

Researchers found that increased use of screen time during infancy was associated with poorer executive functioning once the child was 9 years old, according to the study published Monday in the journal JAMA Pediatrics.

Executive functioning skills are mental processes that “enable us to plan, focus attention, remember instructions, and juggle multiple tasks successfully,” according to the Harvard University Center on the Developing Child.

Those executive functioning skills are important for higher-level cognition, such as emotional regulation, learning, academic achievement and mental health, according to the study. They influence our success socially, academically, professionally and in how we care for ourselves, said Dr. Erika Chiappini, assistant professor of psychiatry and behavioral sciences at the Johns Hopkins University School of Medicine in Baltimore.

“Though these cognitive processes naturally develop from infancy through adulthood, they are also impacted by the experiences that we have and when we have them in our development,” said Chiappini, who was not involved in the study, in an email.

The results support recommendations from the American Academy of Pediatrics, which discourages all screen time before 18 months old, with the exception of video chatting, said Dr. Joyce Harrison, associate professor of psychiatry and behavioral sciences at the Johns Hopkins University School of Medicine. Harrison was not involved in the research.

The study looked at data from Growing Up in Singapore Towards healthy Outcomes, or GUSTO, which surveyed women from all socioeconomic backgrounds during their first trimester of pregnancy. The sample was made up of 437 children who underwent electroencephalography (EEG) scans, which are used to look at the neural pathways of cognitive functions in the brain, at age 1, 18 months and 9 years old.

The parents reported each child’s screen time, and researchers found there was an association between screen time in infancy and attention and executive function at 9 years old, according to the study.

Further research needs to be done, however, to determine if the screen time caused the impairments in executive function or if there are other factors in the child’s environment that predispose them to both more screen time and poorer executive functioning, the study noted.

In a learning-packed time like infancy, one of the big problems with screen use is that young children aren’t learning much from them, according to AAP.

“There is no substitute for adult interaction, modeling and teaching,” Harrison said.

Babies have a hard time interpreting information presented in two dimensions, such as on screens, and have trouble distinguishing fantasy from reality, Chiappini said.

“Babies and kids are also social learners and very much benefit from the back-and-forth interaction with others (adults and kids) which is hard to achieve with screens,” Chiappini said via email.

When it comes to emotional regulation, infants and toddlers can learn from their caregivers when they model self-control or help to label emotions and appropriate expressions, she added.

For example, you can give a young child options for what they can do when they are mad, like taking a break or breathing deeply instead of inappropriate behaviors like hitting, Harrison said.

Talking about emotions can be too abstract for preschool-age kids, and in those cases using color zones to talk about emotions can be helpful, said Dr. Jenny Radesky, a developmental behavioral pediatrician and associate professor of pediatrics at Michigan Medicine C.S. Mott Children’s Hospital. Radesky was not involved in the research.

Calm and content can be green; worried or agitated can be yellow; and upset or angry can be red, using graphics or images of faces to help kids match what they’re feeling with their color zone. To reinforce it, adults can talk about their own emotions in terms of colors in front of their kids, Radesky said in a CNN previous article.

Parents and children can go through the colors together and come up with calming tools for the different zones, she added.

To strengthen those executive function skills, Harrison says it’s important to provide structured engagement where a child can work through solving problems to the extent that they can at their developmental level — instead of having problems solved for them.

And yet, sometimes parents just need to get the laundry done or attend a work meeting, and screens can feel like an effective distraction.

For very young children, it’s probably still best to avoid screen time, Harrison emphasized.

Instead, try to involve the child in house chores, she said.

“Give your toddler some clothes to fold alongside you while you are trying to get laundry done or keep your infant safely in a position where you can make frequent eye contact while you are engaged your chore,” Harrison said via email.

For older preschoolers, save up your screen time to use strategically, she said.

“For example, their one hour of screen time can be reserved for a time when you have an important video meeting to attend,” Harrison said.

And there is some content that can help teach emotional regulation when your tank is empty. Finding media that is aimed at speaking to children directly about emotions — like Daniel Tiger or Elmo Belly Breathing — can be like a meditation instead of distraction, Radesky previously told CNN.

And you can make screen time works better by engaging your child while they watch, Chiappini said. Ask questions like “what is that character feeling?” and “what could they do to help their friend?” she added.

Raising children is a complex and sometimes overwhelming task, and no caregiver can give their child everything they want to all the time, Radesky said.

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Health

Covid-19 is a leading cause of death for children in the US, despite relatively low mortality rate

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CNN
 — 

Covid-19 has become the eighth most common cause of death among children in the United States, according to a study published Monday.

Children are significantly less likely to die from Covid-19 than any other age group – less than 1% of all deaths since the start of the pandemic have been among those younger than 18, according to federal data. Covid-19 has been the third leading cause of death in the broader population.

But it’s rare for children to die for any reason, the researchers wrote, so the burden of Covid-19 is best understood in the context of other pediatric deaths.

“Pediatric deaths are rare by any measure. It’s something that that we don’t expect to happen and it’s a tragedy in a unique way. It’s a really profound event,” said Dr. Sean O’Leary, chair of the American Academy of Pediatrics’ Committee on Infectious Diseases.

“Everyone knows that Covid is the most severe in the elderly and immunocompromised and that it’s less severe in children, but that does not mean it’s a benign disease in children. Just because the numbers are so much lower in children doesn’t mean that they’re not impactful.”

In 2019, the last year before the pandemic, the leading causes of death among children and young adults ages 0 to 19 included perinatal conditions, unintentional injuries, congenital malformations or deformations, assault, suicide, malignant neoplasms, diseases of the heart and influenza and pneumonia.

The researchers’ analysis of data from the US Centers for Disease Control and Prevention found that there were 821 Covid-19 deaths in this age group during a 12-month period from August 2021 to July 2022. That death rate – about 1 for every 100,000 children ages 0 to 19 – ranks eighth compared with the 2019 data. It ranks fifth among adolescents ages 15 to 19.

Covid-19 deaths displace influenza and pneumonia, becoming the top cause of death caused by any infectious or respiratory disease. It caused “substantially” more deaths than any vaccine-preventable disease historically, the researchers wrote.

According to CDC data, children are less vaccinated against Covid-19 than any other age group in the US. Less than 10% of eligible children have gotten their updated booster shot, and more than 90% of children under 5 are completely unvaccinated.

“If we looked at all those other leading causes of death – whether you’re talking about motor vehicle accidents or childhood cancer – and we said, ‘Gosh, if we had some simple, safe thing we could do to get rid of one of those, wouldn’t we just jump at it?” And we have that with Covid with vaccines,” said O’Leary, who is also a professor of pediatric infectious disease at the University of Colorado School of Medicine and Children’s Hospital Colorado.

A CDC survey of blood samples suggest that more than 90% of children have already had Covid-19 at least once.

There is uncertainty about exactly how much risk the virus will continue to pose, O’Leary said, but the potential benefits of vaccination clearly outweigh any potential risks.

“Vaccination clearly is our best option right now,” and the benefits clearly outweigh the risks, he said. “Better safe than sorry.”

The findings of the new study, published in JAMA Network Open, may underestimate the mortality burden of Covid-19 because the analysis focuses on deaths where Covid-19 was an underlying cause of death but not those where it may have been a contributing factor, the researchers wrote. Also, other analyses of excess deaths suggest that Covid-19 deaths have been underreported.

As Covid-19 continues to spread in the US, the researchers say that intervention methods such as vaccination and ventilation will “continue to play an important role in limiting transmission of the virus and mitigating severe disease.”

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World

Peshawar, Pakistan mosque: Suspected suicide attack kills more than 30 people and injures 125

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CNN
 — 

A deadly blast inside a mosque in Pakistan’s northwestern city of Peshawar Monday was likely a suicide attack, according to authorities.

The powerful explosion left at least 31 people dead and 125 injured, according to Peshawar deputy commissioner Shafiullah Khan.

Rescue operations are now underway inside the mosque, which is situated inside a police compound in the city and is mostly attended by law enforcement officials.

No claims of responsibility have been made in relation to the attack so far, which took place in the middle of afternoon prayers.

In a statement to CNN, Peshawar Police Chief Mohammad Aijaz Khan said the blast inside the Police Lines Mosque was “probably a suicide attack,” echoing Pakistan Prime Minister Shehbaz Sharif.

“The brutal killing of Muslims prostrating before Allah is against the teachings of the Quran,” Sharif said in a statement, adding that “targeting the House of Allah is proof that the attackers have nothing to do with Islam.”

“Terrorists want to create fear by targeting those who perform the duty of defending Pakistan,” the prime minister continued.

“Those who fight against Pakistan will be erased from the page.”

Sharif went on to say that “the entire nation and institutions are united to end terrorism” and that there’s a “comprehensive strategy” in the works in order to restore law and order in the northwest Khyber Pakhtunkhwa province, where Peshawar is located.

Pakistan’s former leader Imran Khan, whose party the Pakistan Tehreek e Insaaf holds the provincial government of Khyber Pakhtunkwa also condemned the blast saying in a tweet that “it is imperative we improve our intelligence gathering & properly equip our police forces to combat the growing threat of terrorism.”

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