Tag Archives: blown

The Fallout TV show’s popularity has blown up Nexus Mods as everyone rushes to play Fallout 4 again – Rock Paper Shotgun

  1. The Fallout TV show’s popularity has blown up Nexus Mods as everyone rushes to play Fallout 4 again Rock Paper Shotgun
  2. Fallout 4, Fallout 76, and Other Fallout Games Surge in Popularity, Put Pressure on Mod Site NexusMods IGN
  3. So many people are downloading Fallout mods after watching the show that the Nexus is straining to support all the traffic PC Gamer
  4. Fallout TV Show Is So Popular It’s Breaking Mod Sites Kotaku
  5. The Fallout TV show’s series rebirth continues as Fallout 4 rivals Helldivers 2, the once-maligned MMO hits new heights, and the planet’s biggest mod forum crumbles under pressure Gamesradar

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Chris Hemsworth says acting break comments ‘blown out of proportion’ – USA TODAY

  1. Chris Hemsworth says acting break comments ‘blown out of proportion’ USA TODAY
  2. After Calling ‘Thor 4’ Too Silly, Chris Hemsworth Says ‘Thor 5’ Must Be ‘Unpredictable’: ‘I Don’t Want to Continue’ for So Long That Fans ‘Roll Their Eyes’ Yahoo Entertainment
  3. Why Chris Hemsworth Is Taking A Break From Acting BuzzFeed
  4. Chris Hemsworth on Taking Time Off: Comments Were “Blown Out of Proportion” | THR News The Hollywood Reporter
  5. Chris Hemsworth Explained Why He’s Taking A Break From Acting Yahoo Entertainment
  6. View Full Coverage on Google News

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Russian Commander Watches Friendly Tank Blown to Pieces in Front of Him – Newsweek

  1. Russian Commander Watches Friendly Tank Blown to Pieces in Front of Him Newsweek
  2. Putin’s Army annihilates hidden Ukrainian positions with dreaded Tos-1A ‘flamethrower’ I Watch Hindustan Times
  3. VIDEO: Ukrainian marines wipe out Russian tank column with Javelin missiles Business Insider
  4. Video captures the moment a Ukrainian exploding drone destroyed one of Russia’s prized Tor-M2 missile systems designed to shoot down drones Yahoo News
  5. Heart-pounding moment Ukrainians wipe out entire column of Russian tanks New York Post
  6. View Full Coverage on Google News

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Recently retired JJ Watt blown away by Taylor Swift concert: ‘Unbelievable’ – Fox News

  1. Recently retired JJ Watt blown away by Taylor Swift concert: ‘Unbelievable’ Fox News
  2. Taylor Swift Surprises Concertgoers by Diving from Stage During Eras Tour: ‘Queen of Swimming’ PEOPLE
  3. Taylor Swift’s parents DIY-ed her Fearless guitar with glue and rhinestones a day before tour began Guitar.com
  4. Swiftie calls out other Taylor Swift fans for their mean girl behavior at The Eras Tour: ‘it’s just really gross behavior’ Yahoo Life
  5. JJ Watt reveals how Taylor Swift converted him into a ‘Swiftie’ Marca
  6. View Full Coverage on Google News

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James Webb Space Telescope’s 1st year in space has blown astronomers away

Just one year after launch, the James Webb Space Telescope is exceeding all expectations, and astronomers are thrilled.

Launched on Dec. 25, 2021, the $10 billion infrared observatory was designed to learn how galaxies form and grow, to peer far back into the universe to the era of the first galaxies, to watch stars be born inside their nebulous embryos in unprecedented detail, and to probe the atmospheres of exoplanets and characterize some of the closest rocky worlds.

However, the complexity of the James Webb Space Telescope (Webb or JWST), including its fold-out, segmented 21-foot (6.5 meters) mirror and its delicate sun-shield the size of a tennis court, meant that astronomers were on tenterhooks as to whether the JWST would perform as hoped.

It turns out, they needn’t have worried. “I guess we really weren’t expecting the results to be this good,” Brenda Frye, an astronomy at Steward Observatory at the University of Arizona, told Space.com.

Related: James Webb Space Telescope’s best images of all time (gallery)

The James Webb Space Telescope launched atop an Ariane 5 rocket from French Guiana on Dec. 25, 2021. (Image credit: NASA/Bill Ingalls)

“It’s amazing,” Steve Longmore, an astrophysicist at Liverpool John Moores University in the U.K., told Space.com. “It’s delivering at least as well, and better in a lot of circumstances, than what we were expecting.”

And if it exceeds its own targets, it definitely surpasses those of its predecessors. “It’s leaps and bounds better than what we’ve been able to see before,” Susan Mullally, JWST’s deputy project scientist from the Space Telescope Science Institute (STScI) in Maryland, which operates the observatory, told Space.com, adding that she is “blown away by the imagery, honestly. The images are beautiful.”

The rings of Neptune

The main reason that JWST is performing so well is because of its superlative optics, which are able to achieve their maximum potential resolution for the majority of infrared wavelengths that the telescope observes in. This success means that JWST’s images have a clarity to them that were unobtainable by the likes of the Hubble Space Telescope and NASA’s retired Spitzer Space Telescope, or larger telescopes on the ground such as those at the Keck Observatory in Hawaii, whose vision is blurred by Earth’s atmosphere

But with JWST, individual stars so close together they were once indistinguishable can now be resolved; the structures of very distant galaxies are now discernible; and even something close by such as the rings of Neptune pop with the most detail seen in decades.

The James Webb Space Telescope’s stunning view of Neptune, with its rings clearly visible. (Image credit: NASA/ESA/CSA/STScI)

“When the JWST’s images of Neptune first came out, both Heidi [Hammel, an interdisciplinary scientist on JWST and an expert on the outer planets of the solar system] and myself looked at them, and then at each other, and asked, ‘are we really looking at Neptune’?” Naomi Rowe-Gurney, an astronomer at NASA Goddard Space Flight Center in Maryland, told Space.com. 

Although the Keck Observatory has imaged Neptune’s rings, our most impressive view before JWST came from Voyager 2‘s flyby in 1989. “Heidi had not seen the rings [this well] since Voyager 2, and I had never seen the rings like this because Voyager was before I was born!” Rowe-Gurney said.

Normally, faint details or features around a bright object, such as the dark and tenuous rings around blue Neptune, are difficult to see against the glare of the bright object. To counteract this, an instrument is required to have the characteristic of “high dynamic range” to take in both the faint and the bright at the same time.

“We didn’t realize that JWST would have this amazing dynamic range and be able to resolve really faint things like the rings of Neptune and the small moons and rings of Jupiter,” Rowe-Gurney said.

Alien atmospheres

It’s not only the planets of our solar system that JWST is scrutinizing. A key aim of the telescope is to detect the composition of exoplanets‘ atmospheres using a technique called transmission spectroscopy. As a planet transits its star, the star’s light shines through the planet’s atmosphere, but atoms and molecules within that atmosphere can block some of the light at characteristic wavelengths, which gives away the composition of the atmosphere.

The first exoplanet result released from JWST was the transmission spectrum of WASP-39b, which is a “hot Jupiter” exoplanet orbiting a sun-like star located 700 light-years away. JWST detected carbon dioxide in WASP-39b’s atmosphere, the first time the gas has ever been detected on an exoplanet. Other gases present included carbon monoxide, potassium, sodium, water vapor and sulfur dioxide, the last of which can only be created through photochemistry when atmospheric gases react with the ultraviolet light from the planet’s star — another exoplanet first.

The James Webb Space Telescope’s analysis of the atmospheric composition of WASP-39b. (Image credit: NASA/ESA/CSA/J. Olmsted (STScI))

“I keep being amazed by what we’re able to do with the exoplanet data, like the carbon dioxide and the photochemistry that was found in the atmosphere of WASP-39b,” Mullally said. “That was really cool, and I don’t remember people talking about [detecting photochemistry] ahead of time. I’m really looking forward to seeing what we can do with the terrestrial exoplanets orbiting the cool M-dwarfs and seeing what their atmospheres are made of.”

In particular, the TRAPPIST-1 planetary system of seven worlds orbiting an M-dwarf 40 light-years away is a key target of the JWST. Preliminary results, which failed to detect thick blankets of hydrogen surrounding some of the TRAPPIST-1 worlds, were released during a conference held at STScI in December, but we’ll have to be patient for more comprehensive results from these planets, of which up to four could reside in their star’s habitable zone.

WASP-39b was an easy first target because its star is bright and the planet’s signal is strong. M-dwarfs like TRAPPIST-1 are much fainter, despite being closer.

“We have to wait until we can get enough transits of these guys to build up the signal-to-noise, because you can’t do it with just one or two transits,” Mullally said. “I think we’re going to have to wait until at least the end of the cycle 1 observations [summer 2023] before anybody is going to be in a position to say if they’ve found anything really spectacular.”

Star formation near and far

Another aspect of JWST’s mission is to not only observe exoplanets, but to better understand how they, and their stars, form. Star formation in particular is a crucial process to understand it because it connects so many things in the universe both near and far.

Longmore is leading a study to use JWST to observe frantic star formation in a region at the center of our own Milky Way galaxy, called the central molecular zone, some 26,000 light-years from us. The center of our galaxy hosts the highest concentration of stars, and at our distance they all appear packed in — indistinguishable to the likes of the Hubble Space Telescope — while copious amounts of dust shroud most of them from view in optical light. Look with a large-aperture infrared telescope like JWST, however, and those two concerns are shoved aside.

“These are the JWST’s two capabilities that are going to blow my field apart,” Longmore said. The telescope’s superb optics are able to resolve individual baby stars in the center of the galaxy, and infrared light will pass right through the dust to reach the observatory. 

“Ordinarily, with Hubble, it’s like trying to point your telescope at a brick wall and see through it,” he added, “But the JWST is looking through a window in that wall and can count individual stars.”

The star-forming Pillars of Creation, imaged in mid-infrared by the JWST in what will surely become an iconic picture. (Image credit: NASA/ESA/CSA/STScI/J. DePasquale (STScI)/A. Pagan (STScI))

It’s taking longer to gather all the data from the center of the galaxy, but that’s because it’s such a complex environment, with bright, diffuse emission everywhere, and all that has to be disentangled from the relevant signal of star formation via determined and careful data processing. 

“On all the projects I’m on, people are still fighting with calibration and things, but hopefully in the next six months that will change,” Longmore said. He added an amusing story of how one of his team’s observations had been blighted by a mysterious circle on the image. After deeper investigation, it turned out that this wasn’t some mysterious new phenomenon, but that JWST had previously been looking at bright Jupiter, and the giant planet’s after-image had not yet been properly flushed out of the instrument’s electronic sensors! 

Longmore and his colleagues are targeting the central molecular zone because it is the region in our galaxy that most resembles star-forming conditions in the early universe, when the star-formation rate was high and dense clusters of stars formed. In the Central Molecular Zone, the astronomers intend to measure a property called the initial mass function (IMF), which describes the range of stellar masses in a star-forming nebula. 

Currently, astronomers do not understand what determines why stars form with the masses that they have, only that low-mass stars are much more common than luminous high-mass stars, at least in the local universe. Was this still the case over 13 billion years ago in the first galaxies? Answering that question could help explain both how galaxies formed and what ended the universe’s dark ages.

Deep fields and the first galaxies

After she saw President Joe Biden reveal the first deep-field image from the JWST, of the galaxy cluster SMACS 0723, a “gravitational lens” whose massive gravity magnifies objects behind it, Frye and her student, Massimo Pascale at the University of California, Berkeley, raced to analyze the image. 

“We didn’t sleep for three-and-a-half days, and our paper was one of the first two papers submitted on JWST data,” Frye said. 

Together, they found 42 new gravitationally lensed images of 14 different high-redshift galaxies, galaxies located so far away that the expanding universe has stretched their light, making them appear redder. Further studies and more deep fields followed, and a host of high-redshift candidates were discovered by Frye’s team and others, including some galaxies at record-breaking redshifts of 12, 13 and above; these redshifts mean that we see the galaxies as they existed less than 300 million years after the Big Bang.

These high-redshift galaxies have proven something of a surprise, in that they appear more luminous than models of galaxy formation predicted they should be.

“One possible explanation is that they’re producing too many high-mass stars, that they have a top-heavy IMF,” Longmore said, noting the importance of measuring the IMF in the central molecular zone to understand stellar masses in young neighborhoods. 

Why the IMF would be different over 13.5 billion years ago is not understood, but then again the early universe seems to have been a far more intense place than it is today. “In the present day, galaxies in general are not forming stars so actively, but many galaxies formed stars more actively in the early universe,” Frye said.

Frye is a member of the PEARLS (Prime Extragalactic Area for Reionization and Lensing Science) team. PEARLS is a JWST project to image a variety of deep fields, including two apparently sparse regions of sky and a number of galaxy clusters and proto-clusters, to observe the first few billion years of galaxy formation. 

The PEARLS field looking toward the North Celestial Pole. Inset are numerous types of galaxy, from interacting galaxies to ruby-red dusty star-forming galaxies. (Image credit: NASA/ESA/CSA/Rolf A. Jansen, Jake Summers, Rosalia O’Brien, Rogier Windhorst (ASU)/Aaron Robotham (UWA)/Anton M. Koekemoer (STScI)/Christopher Willmer (University of Arizona)/JWST PEARLS Team)

In December, the PEARLs team released their first dataset, of an extraordinary field of distant galaxies close to the North Ecliptic Pole. This region is directly above the main plane of the Milky Way and so is constantly visible to JWST, and it’s also high above interfering features such as zodiacal dust.

Within the image are a whole host of galaxies. Some interact and some show a clear spiral structure; the collection exhibits a whole range of colors, from cobalt blue to ruby red. The latter are of great interest to Frye.

“We can now observe [in the PEARLS image] an abundance of red disk galaxies, which we think might be red spirals,” Frye said. “This type of galaxy is very interesting because they are analogs of what the Milky Way might have looked like when it was younger.”

The reddening is caused by huge amounts of dust in these galaxies; the dust is the result of rapid formation of massive stars that quickly die in supernova explosions and spill vast amounts of dust into space. Such galaxies are completely hidden from Hubble, but infrared light can pass through the dust and make the galaxies visible to JWST.

“The analogy is a New Year’s Eve fireworks display,” Frye said. “If you have a lot of fireworks going off then eventually they are obscured by dusty smoke.”

The JWST has impressed scientists in the six months that it has been gathering data since becoming fully operational in June, but the real fireworks are still to come with major discoveries awaiting us. 

It’s slow going, requiring patience, Frye said. “There’s too much for any one person to be able to study or understand on really short timescales, it’s going to take us a long time to process all the data.”

The results, though, will be worth it. 

“It’s going to completely change our understanding of our place in the universe, how the solar system formed and evolved, and how the very first stars and galaxies formed,” Mullally said. “We’ve made great headway with this telescope, and it’s going to do spectacular things.”

Follow Keith Cooper on Twitter @21stCenturySETI. Follow us on Twitter @Spacedotcom and on Facebook.



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Scientists Blown Away by the Toughest Material on Earth – “Unexpected Transformation”

Microscopy-generated images showing the path of a fracture and accompanying crystal structure deformation in the CrCoNi alloy at nanometer scale during stress testing at 20 kelvin (-424 °F). The fracture is propagating from left to right. Credit: Robert Ritchie/Berkeley Lab

A new study reveals the profound properties of a simple metal

“In the same units, the toughness of a piece of silicon is one, the aluminum airframe in passenger airplanes is about 35, and the toughness of some of the best steels is around 100. So, 500, it’s a staggering number.” — Robert Ritchie

The team, led by researchers from Lawrence Berkeley National Laboratory (Berkeley Lab) and Oak Ridge National Laboratory, published a study describing their record-breaking findings in the journal Science on December 1, 2022.

“When you design structural materials, you want them to be strong but also ductile and resistant to fracture,” said project co-lead Easo George, the Governor’s Chair for Advanced Alloy Theory and Development at ORNL and the University of Tennessee. “Typically, it’s a compromise between these properties. But this material is both, and instead of becoming brittle at low temperatures, it gets tougher.”

CrCoNi is a subset of a class of metals called high entropy alloys (HEAs). All the alloys in use today contain a high proportion of one element with lower amounts of additional elements added, but HEAs are made of an equal mix of each constituent element. These balanced atomic recipes appear to bestow some of these materials with an extraordinarily high combination of strength and ductility when stressed, which together make up what is termed “toughness.” HEAs have been a hot area of research since they were first developed about 20 years ago, but the technology required to push the materials to their limits in extreme tests was not available until recently.

“The toughness of this material near liquid helium temperatures (20 kelvin, -424 °

“We were able to visualize this unexpected transformation due to the development of fast electron detectors in our electron microscopes, which allow us to discern between different types of crystals and quantify the defects inside them at the resolution of a single nanometer – the width of just a few atoms – which as it turns out, is about the size of the defects in deformed NiCoCr structure.” — Andrew Minor

Using neutron diffraction, electron backscatter diffraction, and transmission electron microscopy, Ritchie, George, and their colleagues at Berkeley Lab, the

The CrMnFeCoNi alloy was also tested at 20 kelvin and performed impressively, but didn’t achieve the same toughness as the simpler CrCoNi alloy.

Forging new products

Now that the inner workings of the CrCoNi alloy are better understood, it and other HEAs are one step closer to adoption for special applications. Though these materials are expensive to create, George foresees uses in situations where environmental extremes could destroy standard metallic alloys, such as in the frigid temperatures of deep space. He and his team at Oak Ridge are also investigating how alloys made of more abundant and less expensive elements – there is a global shortage of cobalt and nickel due to their demand in the battery industry – could be coaxed into having similar properties.

Though the progress is exciting, Ritchie warns that real-world use could still be a ways off, for good reason. “When you are flying on an airplane, would you like to know that what saves you from falling 40,000 feet is an airframe alloy that was only developed a few months ago? Or would you want the materials to be mature and well understood? That’s why structural materials can take many years, even decades, to get into real use.”

Reference: “Exceptional fracture toughness of CrCoNi-based medium- and high-entropy alloys at 20 kelvin” by Dong Liu, Qin Yu, Saurabh Kabra, Ming Jiang, Paul Forna-Kreutzer, Ruopeng Zhang, Madelyn Payne, Flynn Walsh, Bernd Gludovatz, Mark Asta, Andrew M. Minor, Easo P. George and Robert O. Ritchie, 1 December 2022, Science.
DOI: 10.1126/science.abp8070

This research was supported by the Department of Energy’s Office of Science. The low-temperature mechanical testing and neutron diffraction was performed at the ENGIN-X ISIS Facility at the Rutherford Appleton Laboratory, led by first author Dong Liu. Microscopy was performed at the National Center for Electron Microscopy at the Molecular Foundry, a DOE Office of Science user facility at Berkeley Lab. The other authors on this project were Qin Yu, Saurabh Kabra, Ming Jiang, Joachim-Paul Forna-Kreutzer, Ruopeng Zhang, Madelyn Payne, Flynn Walsh, Bernd Gludovatz, and Mark Asta.



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Factbox: Is the Kakhovka dam in Ukraine about to be blown?

Oct 21 (Reuters) – Russia and Ukraine have accused each other of planning to blow up the Kakhovka hydro-electric dam on the Dnipro River, a step that would unleash a devastating flood across a large area of southern Ukraine.

What is the Kakhovka dam, is it about to be blown and what impact would that have?

SIGNIFICANCE OF THE DAM

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* The dam, 30 metres (yards) tall and 3.2 km (2 miles) long, was built in 1956 on the Dnipro river as part of the Kakhovka hydroelectric power plant.

* It holds an 18 km3 reservoir which also supplies water to the Crimean peninsula, annexed by Russia in 2014, and to the Zaporizhzhia nuclear plant, which is also under Russian control.

* The volume of water in the reservoir is about equal to the Great Salt Lake in the U.S. state of Utah.

* Blowing the Soviet-era dam, which is controlled by Russia, would unleash a wall of devastating floodwater across much of the Kherson region which Russia last month proclaimed as annexed in the face of a Ukrainian advance.

* Destroying the Kakhovka hydro-electric power plant would also add to Ukraine’s energy woes after weeks of Russian missile strikes aimed at generation and grid facilities which Kyiv said have damaged a third of its country-wide power network.

ALLEGATIONS

* Sergei Surovikin, the commander of Russian forces in Ukraine, said on Tuesday he had information that Ukrainian forces were preparing a massive strike on the dam and had already used U.S.-supplied HIMARS missiles of a major strike, he said, could be a disaster.

“We have information on the possibility of the Kyiv regime using prohibited methods of war in the area of the city of Kherson, on the preparation by Kyiv of a massive missile strike on the Kakhovka hydro-electric dam,” Surovikin said.

Ukrainian officials said the allegation was a sign that Moscow planned to attack the dam and blame Kyiv.

* Ukrainian President Volodymyr Zelenskiy said on Thursday that Russia had mined the dam and was preparing to blow it, a step he compared to the use of weapons of mass destruction.

“I informed the Europeans today, during the meeting of the European Council, about the next terrorist attack, which Russia is preparing for at the Kakhovka hydroelectric power plant,” he said. “Destroying the dam would mean a large-scale disaster.”

Blowing the dam, he said, would also destroy the water supply to Crimea and thus show that Russia had accepted that it could not hold onto the peninsula.

Kirill Stremousov, the Russian-installed deputy head of the annexed Kherson region, said Kyiv’s allegations that Russia had mined the dam were false.

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Reporting by Reuters; editing by Guy Faulconbridge and Philippa Fletcher

Our Standards: The Thomson Reuters Trust Principles.

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6 Lupus Patients Cured by Cancer Therapy, Doctors ‘Blown Away’

  • A half dozen patients in Germany have been functionally cured of lupus — for now, at least.
  • Their doctors used a blood-engineering technique that’s usually reserved for fighting aggressive cancers (CAR-T).
  • It’s unlikely that such a technique could become widespread for lupus-sufferers, because of the cost and lab work required for each patient.

Doctors in Germany have found a way to effectively cure the most common form of lupus using a novel and pricey blood-infusion technique typically reserved for treating cancer. 

A group of immunologists based in Erlangen, Germany announced in the journal Nature Medicine on Thursday that all five systemic lupus erythematosus (SLE) patients who they treated with CAR-T cells during an investigational, compassionate use trial were in remission by three months after their treatment, and remained so for at least eight months longer.

Lead researcher Georg Schett told STAT that the treatment outcomes were “miraculous,” and the fact that such a therapy course could be used so effectively to combat lupus “blew us away.”

“We were really surprised how effective it was,” he said.  

The find, though still preliminary, suggests that the CAR-T method could one day have a major impact curing the inflammatory, autoimmune disease — if the fix holds in these patients long-term.

For now, the research team is still waiting to see whether the six patients remain “basically healthy” without any more treatments, and “whether there’s really no relapse,” Schett told Insider. 

His latest work builds on an initial research letter that Schett and his colleagues published last year in the New England Journal of Medicine, detailing how one other 20-year-old woman was functionally cured of lupus in the same way. She’s been feeling good for at least 18 months. 

In CAR-T, a patient’s blood is trained to fight disease  

CAR-T for lupus isn’t without drawbacks. It’s both pricey and labor-intensive to produce, meaning this strategy will likely never be a viable treatment option for all 200,000 Americans living with the disease.

Still, “if you fail on the conventional drugs, and you have severe disease, I think this will be — in the future — the time to intervene with CAR-T cell therapy,” Schett explained to Insider, adding that the same strategy could potentially be used to treat other severe autoimmune diseases, including multiple sclerosis. 

Today, CAR-T immunotherapy is usually reserved for treating aggressive cancers like lymphomas, and can cost around $450,000, according to the National Cancer Institute. Part of the reason the treatment is so expensive is because it is highly bespoke, specific to each patient and their disease.

First, blood is extracted from the patient, then it is taken to a lab to have the immune-boosting T cells inside re-engineered with special proteins called chimeric antigen receptors (CARs). Finally, those protein-infused T cells are re-injected into the patient, where they work to kill a target disease (for lupus, the T cells were engineered to fight back against CD19.) 

Remarkably, these German patients’ immune systems remained robust during their CAR-T therapy, with no serious infections or toxic side effects reported. That’s unlike what can happen in cancer patients given CAR-T, who may develop neurological issues, or life-threatening cytokine storms.

“This would seem to be the holy grail of treatment,” Dr. Mark Leick, who was not involved in this lupus study, but who works on CAR-T therapies at Massachusetts General Hospital, told STAT.

The patients are back to riding horses, dancing, and studying

Schett said one of his young patients is riding horses again, another is DJing in clubs, and a third has resumed her studies — activities they all had to largely forgo when they had lupus, as a result of chronic, debilitating fatigue.

For now, CAR-T remains a highly investigational, pricey, experimental fix for just a lucky few lupus sufferers. The typical recommended treatments for the millions of other people with lupus around the world without access to these kinds of special blood-engineering programs are still limited to steroids, anti-inflammatories like ibuprofen to ease symptoms, or, in the most serious cases, expensive monoclonal antibodies. 

But, “if you can really wipe out the disease with a single shot of CAR-T cells and have remission for a long time, I think it’s not that expensive,” Schett said, explaining that in his non-commercial trial doctors spent tens of thousands, not hundreds of thousands, treating every sick patient (they saved on costs by manufacturing their CAR-T cells in house.)

“It’s a young person having their whole life in front of them,” he said. “If you can wipe out a disease when you’re 20 and you don’t get it again, well, then it can cost a little bit and still be economical over the long run.”

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Astronomers “Blown Away” by First Breathtaking Webb Space Telescope Images of Orion Nebula

The inner region of the Orion Nebula as seen by the James Webb Space Telescope’s NIRCam instrument. This is a composite image from several filters that represents emissions from ionized gas, molecular gas, hydrocarbons, dust, and scattered starlight. Most prominent is the Orion Bar, a wall of dense gas and dust that runs from the top left to the bottom right in this image, and that contains the bright star θ2 Orionis A. The scene is illuminated by a group of hot, young massive stars (known as the Trapezium Cluster) which is located just off the top right of the image. The strong and harsh ultraviolet radiation of the Trapezium cluster creates a hot, ionized environment in the upper right, and slowly erodes the Orion Bar away. Molecules and dust can survive longer in the shielded environment offered by the dense Bar, but the surge of stellar energy sculpts a region that displays an incredible richness of filaments, globules, young stars with disks and cavities. Credit: NASA, ESA, CSA, Data reduction and analysis: PDRs4All ERS Team; graphical processing S. Fuenmayor

New Webb pictures reveal spectacular view of Orion Nebula

Young star with disk inside its cocoon: Planet forming disks of gas and dust around a young star. These disks are being dissipated or “photo-evaporated” due to the strong radiation field of the nearby stars of the Trapezium creating a cocoon of dust and gas around them. Almost 180 of these externally illuminated photoevaporating disks around young stars (aka Proplyds) have been discovered in the Orion nebula, and HST-10 (the one in the picture) is one of the largest known. The orbit of Neptune is shown for comparison.
Filaments: The entire image is rich in filaments of different sizes and shapes. The inset here shows thin, meandering filaments that are especially rich in hydrocarbon molecules and molecular hydrogen.
θ2 Orionis A: The brightest star in this image is θ2 Orionis A, a star that is just bright enough to be seen with the naked eye from a dark location on Earth. Stellar light that is reflecting off dust grains causes the red glow in its immediate surroundings.
Young star inside globule: When dense clouds of gas and dust become gravitationally unstable, they collapse into stellar embryos that gradually grow more massive until they can start nuclear fusion in their core – they start to shine. This young star is still embedded in its natal cloud.
Credit: NASA, ESA, CSA, Data reduction and analysis: PDRs4All ERS Team; graphical processing S. Fuenmayor & O. Berné

“These new observations allow us to better understand how massive stars transform the gas and dust cloud in which they are born,” said Peeters. She is a Western astronomy professor and faculty member at the Institute for Earth and Space Exploration.

“Massive young stars emit large quantities of ultraviolet radiation directly into the native cloud that still surrounds them, and this changes the physical shape of the cloud as well as its chemical makeup. How precisely this works, and how it affects further star and planet formation is not yet well known.”

The newly released images reveal numerous spectacular structures inside the nebula, down to scales comparable to the size of the Solar System.

“We clearly see several dense filaments. These filamentary structures may promote a new generation of stars in the deeper regions of the cloud of dust and gas. Stellar systems already in formation show up as well,” said Berné. “Inside its cocoon, young stars with a disk of dust and gas in which planets form are observed in the nebula. Small cavities dug by new stars being blown by the intense radiation and stellar winds of newborn stars are also clearly visible.”

Proplyds, or ionized protoplanetary disks, consist of a central protostar surrounded by a disk of dust and gas in which planets form. Scattered throughout the images are several protostellar jets, outflows, and nascent stars embedded in dust.

“We have never been able to see the intricate fine details of how interstellar matter is structured in these environments, and to figure out how planetary systems can form in the presence of this harsh radiation. These images reveal the heritage of the interstellar medium in planetary systems,” said Habart.

Orion Nebula: JWST versus Hubble Space Telescope (HST): The inner region of the Orion Nebula as seen by both the Hubble Space Telescope (left) and the James Webb Space Telescope (right). The HST image is dominated by emission from hot ionized gas, highlighting the side of the Orion Bar which is facing the Trapezium Cluster (off the top right of the image). The JWST image also shows the cooler molecular material that is slightly further away from the Trapezium Cluster (compare the location of the Orion Bar relative to the bright star θ2 Orionis A for example). Webb’s sensitive infrared vision can furthermore peer through thick dust layers and see fainter stars. This will allow scientists to study what is happening deep inside the nebula.
Credit: NASA, ESA, CSA, PDRs4All ERS Team; image processing Olivier Berné.
Credit for the HST image: NASA/STScI/Rice Univ./C.O’Dell et al. – Program ID: PRC95-45a. Technical details: The HST image used WFPC2 mosaic. This composite image uses [OIII] (blue), ionized hydrogen (green), and [NII] (red).

Analog evolution

The Orion Nebula has long been considered an environment similar to the cradle of the solar system (when it formed more than 4.5 billion years ago). This is why scientists today are interested in observing the Orion Nebula. They hope to understand, by analogy, what happened during the first million years of our planetary evolution.

Because the hearts of stellar nurseries like the Orion Nebula are obscured by large amounts of stardust, it makes it impossible to study what is happening inside them in visible light with telescopes like the Hubble Space Telescope. Webb detects the infrared light of the cosmos, which allows astronomers to see through these layers of dust and reveal the action happening deep inside the Nebula.

The inner region of the Orion Nebula as seen by both the Spitzer Space Telescope (left) and the James Webb Space Telescope (right). Both images were recorded with a filter that is particularly sensitive to the emission from hydrocarbon dust that glows throughout the entire image. This comparison strikingly illustrates how incredibly sharp Webb’s images are in comparison to its infrared precursor, the Spitzer Space Telescope. This is immediately clear from the intricate filaments, but Webb’s sharp eyes also allow us to better distinguish stars from globules and protoplanetary disks.
Credit for NIRCam image: NASA, ESA, CSA, PDRs4All ERS Team; image processing Olivier Berné.
Credit for the Spitzer image: NASA/JPL-Caltech/T. Megeath (University of Toledo, Ohio)
Technical details: The Spitzer image shows infrared light at 3.6 microns captured by Spitzer’s infrared array camera (IRAC). The JWST image shows infrared light at 3.35 microns captured by JWST NIRCam. Black pixels are artifacts due to saturation of the detectors by bright stars.

“Observing the Orion Nebula was a challenge because it is very bright for Webb’s unprecedented sensitive instruments. But Webb is incredible, Webb can observe distant and faint galaxies, as well as

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Rare and bizarre tentacle-trailing sea creature caught on video, expedition scientist’s ‘mind is blown’

New footage showing a giant, peculiar-looking tentacled sea creature floating languidly in the depths of the Pacific Ocean has left researchers questioning if what they’re seeing is a new species.

A team of scientists spotted the strange animal while on board the E/V Nautilus, a research vessel used by the Ocean Exploration Trust — a nonprofit organization conducting deep-sea research. In a recently released video (opens in new tab), the expedition researchers oohed and aahed as images of the bizarre creature came into focus. “My mind is blown right now,” one of the scientists on board can be heard saying off-camera, as the boat’s remotely operated vehicle (ROV) scanned the ocean floor and inched closer to the strange sight. “I’m not on the edge of my seat or nothing,” another scientist quipped.   

Moments later, the scientists spied another of the oddball creatures nearby, though they were unable to record video of the second individual.

With tentacles extending 16 inches (40 centimeters) from a nearly 7-foot-long (2 meters) stalk, and a single feeding polyp with barbed tentacles cupping the polyp like spiky petals, the creature resembled a very strange, free-swimming flower that was roughly the size of the ROV. It was spotted July 7 at 9,823 feet (2,994 m) below the surface near a previously unexplored seamount north of Johnston Atoll, an unincorporated U.S. territory and a National Wildlife Refuge in the Pacific Ocean west of Hawaii.

Researchers initially suspected that they had crossed paths with Solumbellula monocephalus, also known as a Solumbellula sea pen, which is part of the Cnidaria phylum that includes jellyfish, hydras and coral. However, the only known sightings of sea pens prior to this have occurred in the Atlantic and Indian oceans, so it’s possible that the scientists may have stumbled upon a new species.

Related: 10 weird creatures found in the deep sea in 2021

Steve Auscavitch, the expedition’s lead researcher and a deep-sea biologist and post-doctoral scholar at Boston University, described the sighting as “fascinating.”

“From time to time, we come across something that we never expected to see, and those are often the most powerful observations,” he told Live Science.

He added, “We were nearing the end of our cruise and were at the bottom of the seafloor when we observed the two [sea pens]. The one we captured on video was massive, possibly the same size or larger than Hercules, our ROV. When I saw this amazing sea pen on video, I knew exactly what it could be.”

But just to be sure, Auscavitch sought input from biologists on shore, who helped confirm his suspicions that it was a sea pen, a coral relative. Based on the animal’s impressive size, Auscavitch surmised that it was rather old, however he can’t give a specific age. (Sea pens reach maturity (opens in new tab) at five or six years of age, and can live for more than a decade.) 

“Prior to this, Solumbellula monocephalus had never been seen in the central Pacific and never collected,” he said.

Interestingly, his team’s discovery came several months after scientists in Spain named two new genera of sea pens: Pseudumbellula. and Solumbellula , the latter of which would include the new species. Those findings were published in February in the journal Invertebrate Systematics (opens in new tab).

However, Auscavitch said that more research needs to be done to determine if this is the first Pacific Solumbellula monocephalus or potentially a new species in the ocean basin.  

“Findings like this are rare, and we never expected to see something like this,” he said. “The most exciting part of this research is that we come across these things from time to time, and it really does expand our horizon about where animals can live and exist in the deep sea.”

Originally published on Live Science.

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