Scientists have identified a molecule in the blood, created during exercise, that can effectively reduce food intake and obesity in mice.
The benefits of exercise in a pill? Science is now closer to that goal.
Researchers have identified a molecule in the blood that is produced during exercise and can effectively reduce food intake and obesity in mice. The discovery improves our understanding of the physiological processes that underlie the interplay between exercise and hunger. Scientists from Baylor College of Medicine, Stanford School of Medicine and collaborating institutions reported the findings on June 15 in the journal Nature.
“Regular exercise has been proven to help weight loss, regulate appetite, and improve the metabolic profile, especially for people who are overweight and obese,” said co-corresponding author Dr. Yong Xu, professor of pediatrics – nutrition and molecular and cellular biology at Baylor. “If we can understand the mechanism by which exercise triggers these benefits, then we are closer to helping many people improve their health.”
“We wanted to understand how exercise works at the molecular level to be able to capture some of its benefits,” said co-corresponding author Jonathan Long, MD, assistant professor of pathology at Stanford Medicine and an Institute Scholar of Stanford ChEM-H (Chemistry, Engineering & Medicine for Human Health). “For example, older or frail people who cannot exercise enough, may one day benefit from taking a medication that can help slow down osteoporosis, heart disease or other conditions.”
Xu, Long, and their colleagues conducted comprehensive analyses of blood
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