Tag Archives: woolly

Scientists Are Reincarnating the Woolly Mammoth to Return in 4 Years

Scientists Reincarnating the Woolly MammothTheCrimsonMonkey – Getty Images

  • Colossal recently added $60 million in funding to move toward a 2027 de-extinction of the woolly mammoth.

  • The Dallas-based company is now working to edit the genes for the reincarnation of the mammal.

  • Colossal planned to reintroduce the woolly mammoth into Russia, but that may shift.

The long-dead woolly mammoth will make its return from extinction by 2027, says Colossal, the biotech company actively working to reincarnate the ancient beast.

Last year, the Dallas-based firm scored an additional $60 million in funding to continue the, well, mammoth gene-editing work it started in 2021. If successful, not only will Colossal bring back an extinct species—one the company dubs a cold-resistant elephant—but it will also reintroduce the woolly mammoth to the same ecosystem in which it once lived in an effort to fight climate change, according to a recent Medium post.

Colossal calls the woolly mammoth’s vast migration patterns an active part of preserving the health of the Arctic, and so bringing the animal back to life can have a beneficial impact on the health of the world’s ecosystem. While Colossal originally hoped to reintroduce the woolly mammoth into Siberia, the company may explore other options based on the current political framework of the world.

The woolly mammoth’s DNA is a 99.6 percent match of the Asian elephant, which leads Colossal to believe it’s well on its way toward achieving its goal. “In the minds of many, this creature is gone forever,” the company says. “But not in the minds of our scientists, nor the labs of our company. We’re already in the process of the de-extinction of the Woolly Mammoth. Our teams have collected viable DNA samples and are editing the genes that will allow this wonderful megafauna to once again thunder through the Arctic.”

Through gene editing, Colossal scientists will eventually create an embryo of a woolly mammoth. They will place the embryo in an African elephant to take advantage of its size and allow it to give birth to the new woolly mammoth. The eventual goal is to then repopulate parts of the Arctic with the new woolly mammoth and strengthen local plant life with the migration patterns and dietary habits of the beast.

If Colossal proves successful on reincarnating the woolly mammoth—ditto the thylacine, also known as the Tasmanian tiger—expect a variety of new ethical questions to arise on how to handle the creature and potential reintroduction issues.

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The CIA wants to bring woolly mammoths back from extinction

The CIA is funding research into resurrecting extinct animals — including the woolly mammoth and tiger-like thylacine — according to news reports.

Via a venture capital investment firm called In-Q-Tel, which the CIA funds, the American intelligence agency has pledged money to the Texas-based tech company Colossal Biosciences. According to Colossal’s website, the company’s goal is to “see the woolly mammoth thunder upon the tundra once again” through the use of genetic engineering — that is, using technology to edit an organism’s DNA.

Colossal has also stated an interest in resurrecting the extinct thylacine, or Tasmanian tiger — a wolf-like marsupial that went extinct in the 1930s — as well as the extinct dodo bird.

For their part, the CIA is less interested in thundering mammoths and roaring thylacines than it is in the underlying genetic engineering technology that Colossal intends to develop, according to an In-Q-Tel blog post.

“Strategically, it’s less about the mammoths and more about the capability,” In-Q-Tel’s senior officials wrote.

De-extinction may sound like science fiction — and, to an extent, it is. There is no way to bring back the woolly mammoth as it was ten thousand  years ago; however, by using DNA editing tools, scientists can insert cold-resistant characteristics into the DNA sequences of modern elephants, making them genetically similar to woolly mammoths. The resulting creature wouldn’t be a mammoth, per se; rather, it would be a proxy animal that’s more like an elephant with mammoth-like characteristics.

The foundation of this process is a gene editing method called CRISPR — genetic “scissors” that scientists can use to cut, paste and replace specific gene sequences into an organism’s DNA. (Several of the researchers behind CRISPR won the 2020 Nobel Prize in chemistry).

According to the In-Q-Tel blog post, investing in this project will help the U.S. government to “set the ethical, as well as the technological, standards” for genetic engineering technology, and keep the U.S. a step ahead of competing nations that may also be interested in reading, writing and altering genetic code.

Not everyone is so optimistic about using genetic engineering tools to revive extinct animals. Critics have warned that, even if a company is able to engineer a healthy proxy mammoth, the mammoth’s natural habitat no longer exists — and, even if it did, genetic code cannot teach an animal how to thrive in an unfamiliar ecosystem, according to Gizmodo. Some scientists also argue that money spent on de-extinction projects could go much further if applied to the conservation of living animals.

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Woolly mammoths are making a comeback. Should we eat them?

And what hairy beast, its hour come at last, slouches towards a laboratory to be born?

Some 3,900 years ago, on mainland Siberia, the last known woolly mammoth breathed its last. Since then, humans have known mammoths only through their remnants: scattered bones and a small number of frozen carcasses, complete with the tatty remnants of once-shaggy fur. These remains have, for centuries, provoked our curiosity – curiosity that might one day be sated. Colossal Biosciences, a Texas-based start-up, is using genetic engineering in its quest to bring the species back to life.

“The woolly mammoth was the custodian of a healthier planet,” the company says. Using salvaged mammoth DNA, Colossal will genetically edit Asian elephants, the species’ closest extant cousin. If its plans are successful, then it will produce a woolly mammoth – or as close as possible a replica – six years from now. This year, the company has raised $75m from investors.

Thus, about 3,906 years after it thought it had seen the back of us, the woolly mammoth might be reacquainted with humans – a species that has never seen a large mammal that it didn’t like the idea of eating. Their extinction wasn’t solely our responsibility – the end of the ice age massively reduced the size of their potential habitat – but, as some palaeontologists argue, pre-history is littered with the bodies of megafauna we’ve eaten to extinction. Giant sloths, giant armadillos, dire wolves… whoever was presenting Planet Earth in those days would have had to stay on their toes.

Given the apparent progress in the field of reconstituting the mammoth, we might as well answer the obvious question: should we eat them? Colossal has made no mention of this prospect, focusing instead on the environmental benefits of mammoth restoration: the animal’s heavy gait thickens permafrost, or the permanently frozen layer of soil, gravel and sand under the Earth’s surface, preventing it from melting and releasing greenhouse gases. “If the Mammoth Steppe ecosystem could be revived,” the company argues, “it could help in reversing the rapid warming of the climate and more pressingly, protect the Arctic’s permafrost – one of the world’s largest carbon reservoirs.”

Still, one wonders whether people will be tempted to have a taste, just as their ancestors did. We will have to decide at some point whether we, too, want to eat woolly mammoth – and indeed any other species we choose to resurrect. Would you eat them?

Holly Whitelaw, director of Regenerative Food and Farming, says she’d be up for it. “I would eat anything that was holistically grazed,” says Whitelaw. Roaming animals, she says, are healthy for soil; they distribute seeds and microbes as they wander. The healthier the Arctic soil, the more grassland it supports, and the more carbon is removed from the atmosphere. “It’s like bringing the wolves back,” Whitelaw says. “You get that whole tier of the system working better again.”



It would be a great tragedy if we were to heave these majestic individuals into our time just to use and exploit them for our own benefit

Victoria Herridge, a palaeontologist at the Natural History Museum and an expert on woolly mammoths, has called for caution. In carrying out this kind of environmental project, Dr Herridge told The Telegraph, “you are carrying out a bio-engineering experiment which, if your goal is [met], will create change at a global scale. It becomes a question of: who gets to tamper with the climate system of the planet?”

Speaking to The Independent, Dr Herridge expressed additional concerns about the provenance of these mammoths. “I have a problem with anything to do with surrogate mothers,” she says. The genetically modified mammoth amalgams will gestate within Asian elephants, risking them significant pain and medical risk.

These are objections to the project itself, rather than to the idea of eating mammoth meat at the end of it. Dr Herridge sees this scenario as unlikely, but poses a hypothetical scenario in which she would consider eating mammoth meat. “Fast-forward 100 years. Imagine that Siberia isn’t a bog, there’s a place for woolly elephants to roam, they’re not wading through mosquito-infested swamp. Let’s say they’ve managed to breed 20,000 woolly elephants at this point. They’ve wandered across to Banff and they’re causing havoc, and to maintain that population they had to have an annual cull. Would I turn it down? No. But there are so many caveats.”

Whitelaw says that pasture-raised mammoth would have a good ratio of omega:3 to omega:6 fats, making it a good dietary choice. With this in mind, it’s easy to imagine Paleo enthusiasts providing consumer demand. Dr Herridge, though, is again sceptical. “The idea that you can have a diet that harks back to this ancient way is really problematic,” she says. “There’s this naive idea that there’s a lost Eden. Our vision of it is based on nothing but wishful thinking and stereotypes.”

Tonight’s dinner? Woolly mammoths in the 2016 film ‘Ice Age: Collision Course’

(Shutterstock)

There are other ways of looking at this question. Thinkers such as Brian Tomasik, author of the blog Essays on Reducing Suffering, argue that if you’re going to eat animals, “it’s generally better to eat larger ones so that you get more meat per horrible life and painful death. For example, a beef cow yields over 100 times as much meat per animal as a chicken, so switching from eating all chicken to all beef would reduce the number of farmed animals killed by more than 99 per cent.”

Considering the question of eating woolly mammoths, Tomasik says: “A woolly mammoth would weigh roughly 10 times as much as a beef cow, so eating mammoths rather than smaller animals would reduce the number of animal deaths even more.”

We should also consider the manner of the mammoth’s death. “Whether death by hunting would be better or worse than a natural death in the wild,” Tomasik says, “depends on how long it would take for the mammoth to die after being shot, and how painful the gunshot wound was until the point of death.” Wild deer, he says, can take 30-60 minutes to die after being shot in the lungs or heart. Their brains are considered too small a target, though that could be different for mammoths.

There are many competing considerations here. Although the rejuvenation of Arctic grasslands would probably be good for the climate, it might also entail higher numbers of wild animals. Tomasik views this as bad news. “Almost all wild animals are invertebrates or small vertebrates that produce vast numbers of offspring, most of whom die painfully not long after being born.”



I think it’ll be a bit like pork

More trenchant opposition to the idea comes from Elisa Allen, PETA’s vice-president of programmes. Arguing that we ought to focus on protecting existing species, whose habitats are fast disappearing, rather than resurrect species whose habitats are already lost, Allen says: “If anything distinguishes humans from the rest of the animal kingdom, it is the selfish desire to eat the other members of it when we don’t have to.” Allen says that “the future of the meat industry lies in lab-grown or 3D-printed meat”.

Jacy Reese Anthis, co-founder of the Sentience Institute, sees the application of this technology to woolly mammoths as ethically preferable to hunting them. “One of humanity’s most pressing challenges for the 21st century is to end the unethical, unsustainable industry of factory farming,” he says. “Cultured meat is one of the most promising substitutes, so if mammoth meat is what gets people excited about that, then I’m excited about it. It would be extremely wasteful to breed and farm live mammoths when we could sustainably grow meat tissue in bioreactors.”

This would avoid what Anthis sees as the inherent wrongness of killing, for our own pleasure, a creature that can think and feel. He is all for technology, he says, but stresses that it is important “to maintain boundaries of respect and bodily integrity for sentient beings. One of the most fruitful boundaries has been the right to not be owned and exploited for another’s benefit. This applies to humans but increasingly we recognise it for animals, and it is a crucial pillar in responsible stewardship of our fellow creatures.

“It would be a great tragedy if we were to reach our technological arm back into the Pleistocene and heave these majestic individuals into our time just to use and exploit them for our own benefit.”

For our ancestors, who made buildings out of the bones of mammoths, this issue wouldn’t have been half so hairy. But let’s imagine a mammoth-based dish derived not from hunting but from a bioreactor. How might it taste? Whitelaw has a guess. “I think it’ll be a bit like pork. You’ll have to cook it long and slow to render that fat down to make it. Or maybe you could make it nice and crispy.”

Mind out for that fur, though.

Read original article here

Woolly mammoths are making a comeback. Should we eat them?

And what hairy beast, its hour come at last, slouches towards a laboratory to be born?

Some 3,900 years ago, on mainland Siberia, the last known woolly mammoth breathed its last. Since then, humans have known mammoths only through their remnants: scattered bones and a small number of frozen carcasses, complete with the tatty remnants of once-shaggy fur. These remains have, for centuries, provoked our curiosity – curiosity that might one day be sated. Colossal Biosciences, a Texas-based start-up, is using genetic engineering in its quest to bring the species back to life.

“The woolly mammoth was the custodian of a healthier planet,” the company says. Using salvaged mammoth DNA, Colossal will genetically edit Asian elephants, the species’ closest extant cousin. If its plans are successful, then it will produce a woolly mammoth – or as close as possible a replica – six years from now. This year, the company has raised $75m from investors.

Thus, about 3,906 years after it thought it had seen the back of us, the woolly mammoth might be reacquainted with humans – a species that has never seen a large mammal that it didn’t like the idea of eating. Their extinction wasn’t solely our responsibility – the end of the ice age massively reduced the size of their potential habitat – but, as some palaeontologists argue, pre-history is littered with the bodies of megafauna we’ve eaten to extinction. Giant sloths, giant armadillos, dire wolves… whoever was presenting Planet Earth in those days would have had to stay on their toes.

Given the apparent progress in the field of reconstituting the mammoth, we might as well answer the obvious question: should we eat them? Colossal has made no mention of this prospect, focusing instead on the environmental benefits of mammoth restoration: the animal’s heavy gait thickens permafrost, or the permanently frozen layer of soil, gravel and sand under the Earth’s surface, preventing it from melting and releasing greenhouse gases. “If the Mammoth Steppe ecosystem could be revived,” the company argues, “it could help in reversing the rapid warming of the climate and more pressingly, protect the Arctic’s permafrost – one of the world’s largest carbon reservoirs.”

Still, one wonders whether people will be tempted to have a taste, just as their ancestors did. We will have to decide at some point whether we, too, want to eat woolly mammoth – and indeed any other species we choose to resurrect. Would you eat them?

Holly Whitelaw, director of Regenerative Food and Farming, says she’d be up for it. “I would eat anything that was holistically grazed,” says Whitelaw. Roaming animals, she says, are healthy for soil; they distribute seeds and microbes as they wander. The healthier the Arctic soil, the more grassland it supports, and the more carbon is removed from the atmosphere. “It’s like bringing the wolves back,” Whitelaw says. “You get that whole tier of the system working better again.”



It would be a great tragedy if we were to heave these majestic individuals into our time just to use and exploit them for our own benefit

Victoria Herridge, a palaeontologist at the Natural History Museum and an expert on woolly mammoths, has called for caution. In carrying out this kind of environmental project, Dr Herridge told The Telegraph, “you are carrying out a bio-engineering experiment which, if your goal is [met], will create change at a global scale. It becomes a question of: who gets to tamper with the climate system of the planet?”

Speaking to The Independent, Dr Herridge expressed additional concerns about the provenance of these mammoths. “I have a problem with anything to do with surrogate mothers,” she says. The genetically modified mammoth amalgams will gestate within Asian elephants, risking them significant pain and medical risk.

These are objections to the project itself, rather than to the idea of eating mammoth meat at the end of it. Dr Herridge sees this scenario as unlikely, but poses a hypothetical scenario in which she would consider eating mammoth meat. “Fast-forward 100 years. Imagine that Siberia isn’t a bog, there’s a place for woolly elephants to roam, they’re not wading through mosquito-infested swamp. Let’s say they’ve managed to breed 20,000 woolly elephants at this point. They’ve wandered across to Banff and they’re causing havoc, and to maintain that population they had to have an annual cull. Would I turn it down? No. But there are so many caveats.”

Whitelaw says that pasture-raised mammoth would have a good ratio of omega:3 to omega:6 fats, making it a good dietary choice. With this in mind, it’s easy to imagine Paleo enthusiasts providing consumer demand. Dr Herridge, though, is again sceptical. “The idea that you can have a diet that harks back to this ancient way is really problematic,” she says. “There’s this naive idea that there’s a lost Eden. Our vision of it is based on nothing but wishful thinking and stereotypes.”

Tonight’s dinner? Woolly mammoths in the 2016 film ‘Ice Age: Collision Course’

(Shutterstock)

There are other ways of looking at this question. Thinkers such as Brian Tomasik, author of the blog Essays on Reducing Suffering, argue that if you’re going to eat animals, “it’s generally better to eat larger ones so that you get more meat per horrible life and painful death. For example, a beef cow yields over 100 times as much meat per animal as a chicken, so switching from eating all chicken to all beef would reduce the number of farmed animals killed by more than 99 per cent.”

Considering the question of eating woolly mammoths, Tomasik says: “A woolly mammoth would weigh roughly 10 times as much as a beef cow, so eating mammoths rather than smaller animals would reduce the number of animal deaths even more.”

We should also consider the manner of the mammoth’s death. “Whether death by hunting would be better or worse than a natural death in the wild,” Tomasik says, “depends on how long it would take for the mammoth to die after being shot, and how painful the gunshot wound was until the point of death.” Wild deer, he says, can take 30-60 minutes to die after being shot in the lungs or heart. Their brains are considered too small a target, though that could be different for mammoths.

There are many competing considerations here. Although the rejuvenation of Arctic grasslands would probably be good for the climate, it might also entail higher numbers of wild animals. Tomasik views this as bad news. “Almost all wild animals are invertebrates or small vertebrates that produce vast numbers of offspring, most of whom die painfully not long after being born.”



I think it’ll be a bit like pork

More trenchant opposition to the idea comes from Elisa Allen, PETA’s vice-president of programmes. Arguing that we ought to focus on protecting existing species, whose habitats are fast disappearing, rather than resurrect species whose habitats are already lost, Allen says: “If anything distinguishes humans from the rest of the animal kingdom, it is the selfish desire to eat the other members of it when we don’t have to.” Allen says that “the future of the meat industry lies in lab-grown or 3D-printed meat”.

Jacy Reese Anthis, co-founder of the Sentience Institute, sees the application of this technology to woolly mammoths as ethically preferable to hunting them. “One of humanity’s most pressing challenges for the 21st century is to end the unethical, unsustainable industry of factory farming,” he says. “Cultured meat is one of the most promising substitutes, so if mammoth meat is what gets people excited about that, then I’m excited about it. It would be extremely wasteful to breed and farm live mammoths when we could sustainably grow meat tissue in bioreactors.”

This would avoid what Anthis sees as the inherent wrongness of killing, for our own pleasure, a creature that can think and feel. He is all for technology, he says, but stresses that it is important “to maintain boundaries of respect and bodily integrity for sentient beings. One of the most fruitful boundaries has been the right to not be owned and exploited for another’s benefit. This applies to humans but increasingly we recognise it for animals, and it is a crucial pillar in responsible stewardship of our fellow creatures.

“It would be a great tragedy if we were to reach our technological arm back into the Pleistocene and heave these majestic individuals into our time just to use and exploit them for our own benefit.”

For our ancestors, who made buildings out of the bones of mammoths, this issue wouldn’t have been half so hairy. But let’s imagine a mammoth-based dish derived not from hunting but from a bioreactor. How might it taste? Whitelaw has a guess. “I think it’ll be a bit like pork. You’ll have to cook it long and slow to render that fat down to make it. Or maybe you could make it nice and crispy.”

Mind out for that fur, though.

Read original article here

Ancient DNA Discovery Reveals Woolly Mammoths, Wild Horses Survived Thousands of Years Longer Than Believed

Researchers used DNA capture-enrichment technology developed at McMaster to isolate and rebuild the fluctuating animal and plant communities during the Pleistocene-Holocene transition. Credit: Julius Csotonyi

Mere spoonsful of soil pulled from Canada’s permafrost are opening vast windows into ancient life in the Yukon, revealing rich new information and rewriting previous beliefs about the extinction dynamics, dates, and survival of megafauna like mammoths, horses, and other long-lost life forms.

In a new paper, published in the journal Nature Communications, researchers from McMaster University, the University of Alberta, the American Museum of Natural History, and the Yukon government present a 30,000-year

Cored permafrost sediments are extracted from the Klondike region of central Yukon. Credit: Tyler Murchie

They reconstructed the ancient ecosystems using tiny soil samples which contain billions of microscopic genomic sequences from animal and plant species.

The analysis reveals that mammoths and horses were already in steep decline prior to the climatic instability, but they did not immediately disappear due to human overhunting as previously thought. In fact, the DNA evidence shows that both the woolly mammoth and North American horse persisted until as recently as 5,000 years ago, bringing them into the mid-Holocene, the interval beginning roughly 11,000 years ago that we live in today.

Through the early Holocene the Yukon environment continued to experience massive change. Formerly rich grasslands—the “Mammoth Steppe”—were overrun with shrubs and mosses, species no longer held in check by large grazing herds of mammoths, horses, and bison. Today, grasslands do not prosper in northern North America, in part because there are no megafaunal “ecological engineers” to manage them.

Tyler Murchie is a postdoctoral researcher in McMaster’s Department of Anthropology and a lead author of the study. Credit: Georgia Kirkos

“The rich data provides a unique window into the population dynamics of megafuana and nuances the discussion around their extinction through more subtle reconstructions of past ecosystems,” says evolutionary geneticist Hendrik Poinar, a lead author on the paper and director of the McMaster Ancient DNA Centre.

This work builds on previous research by McMaster scientists who had determined woolly mammoths and the North American horse were likely present in the Yukon approximately 9,700 years ago. Better techniques and further investigation have since refined the earlier analysis and pushed forward the date even closer to contemporary time.

Hendrik Poinar is an evolutionary geneticist, a lead author on the paper and director of the McMaster Ancient DNA Center. Credit: Georgia Kirkos

“Now that we have these technologies, we realize how much life-history information is stored in permafrost,” explains Tyler Murchie, a postdoctoral researcher in McMaster’s Department of Anthropology and a lead author of the study.

“The amount of genetic data in permafrost is quite enormous and really allows for a scale of ecosystem and evolutionary reconstruction that is unparalleled with other methods to date,” he says.

“Although mammoths are gone forever, horses are not,” says Ross MacPhee of the American Museum of Natural History, another co-author. “The horse that lived in the Yukon 5,000 years ago is directly related to the horse species we have today, Equus caballus. Biologically, this makes the horse a native North American mammal, and it should be treated as such.”

Scientists also stress the need to gather and archive more permafrost samples, which are at risk of being lost forever as the Arctic warms.

Reference: “Collapse of the mammoth-steppe in central Yukon as revealed by ancient environmental DNA” by Tyler J. Murchie, Alistair J. Monteath, Matthew E. Mahony, George S. Long, Scott Cocker, Tara Sadoway, Emil Karpinski, Grant Zazula, Ross D. E. MacPhee, Duane Froese and Hendrik N. Poinar, 8 December 2021, Nature Communications.
DOI: 10.1038/s41467-021-27439-6



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