Tag Archives: Weakness

Arrowhead’s latest major order is exploiting the Helldiver 2 community’s greatest weakness: communication – PC Gamer

  1. Arrowhead’s latest major order is exploiting the Helldiver 2 community’s greatest weakness: communication PC Gamer
  2. Game master Joel cuts an unprecedented deal with Helldivers 2 players: Pull off the ‘Martale Gambit’ and he’ll liberate two planets for the price of one PC Gamer
  3. As Helldivers 2 players struggle with a brutal Major Order, dev says GM Joel secretly helps them out: “Short of handing you the win, there isn’t a lot more we can do” Gamesradar
  4. Helldivers 2 faces “grim projections” after we beat two billion bugs PCGamesN
  5. Helldivers 2 dev “looking into” progress tracking and display issues Eurogamer.net

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One thing we learned about each NFL team in Week 3: Dolphins run better than pass, Cowboys’ major weakness – CBS Sports

  1. One thing we learned about each NFL team in Week 3: Dolphins run better than pass, Cowboys’ major weakness CBS Sports
  2. NFL Week 3 Stock Check: Dolphins Set Records, Buffalo Bullies, Bears Embarrass (Taylor’s Version) bleachernation.com
  3. Rest of season fantasy football rankings following NFL Week 3 | Fantasy Football News, Rankings and Projections Pro Football Focus
  4. NFL Week 3 grades: Eagles and Bengals each earn an ‘A-‘ for big wins on Monday night CBS Sports
  5. Five Things I Think I Think About the Miami Dolphins – Week 3 2023 The Phinsider
  6. View Full Coverage on Google News

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Jimmie Allen Apologizes to Wife for ‘Weakness’ and Calls Himself ‘Victim’ of Temptation After Explosive Lawsuit Accusing Him of Rape – Variety

  1. Jimmie Allen Apologizes to Wife for ‘Weakness’ and Calls Himself ‘Victim’ of Temptation After Explosive Lawsuit Accusing Him of Rape Variety
  2. Jimmie Allen Returns to Instagram with ‘This Too Shall Pass’ Comment amid Sexual Assault Allegations Yahoo Entertainment
  3. Jimmie Allen Issues Public Apology to Estranged Wife Alexis for Affair PEOPLE
  4. Suspended from his record label, dropped from a business deal and more: The fallout from a country singer’s sexual assault, false imprisonment scandal Wonderwall
  5. Jimmie Allen apologizes for ‘humiliating’ estranged wife with ‘affair’ amid accusations of sexual assault Yahoo Entertainment
  6. View Full Coverage on Google News

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‘What is happening?’ New Yamaha weakness alarms Quartararo – The Race

  1. ‘What is happening?’ New Yamaha weakness alarms Quartararo The Race
  2. MotoGP 2023 Official Sepang MotoGP Test results – Day 3 lap times (Sunday) | MotoGP | Crash- 2023 Official MotoGP Pre-season Test – Sepang, Malaysia 2023 Official Sepang MotoGP Test results – Day 3 lap times (Sunday) | MotoGP Crash
  3. 2023 Yamaha MotoGP bike “a nightmare” in qualifying trim – Quartararo Motorsport.com
  4. MotoGP, Marc Marquez: Kawauchi wants to see with his own eyes what doesn’t work GPOne.com
  5. Marquez: “Don’t infect engineers with ideas – I was not asking…” Crash
  6. View Full Coverage on Google News

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One thing we learned about each NFL team in Week 12: Chiefs’ major weakness unveiled; Broncos star CB in slump

The NFL certainly had an interesting Week 12 slate of games, including a record number of comebacks. Sunday was the first time in NFL history that four teams won after trailing by seven-plus points in the final two minutes of regulation. In all, five games were decided by a game-winning score in the final two minutes of regulation or in overtime this week.

The Jacksonville Jaguars and Los Angeles Chargers scored the game-winning points on a two-point conversion in the final 15 seconds of the fourth quarter, the first time in NFL history this has occurred on the same day (and just the third and fourth time overall). The league has seen the most comebacks through 12 weeks in history. 

As the league switches into December, here’s one thing we learned about each team in Week 12  with the playoff races heating up. 

Kyler Murray finally has DeAndre Hopkins and Marquise Brown in the lineup: It only took the Cardinals until the last week of November to finally have their top two receivers in the lineup. Hopkins and Brown combined for 10 catches (on 14 targets) for 133 yards and a touchdown in the loss to the Chargers. 

Even with both of his top receivers in the lineup, Murray averaged just 6.6 yards per attempt (slightly above his season average of 6.4). The Cardinals also went three-and-out on their last three possessions, targeting Brown and Hopkins only once. That’s unacceptable. 

Arizona has added weapons in its offense, yet the results remain the same. 

Tackling remains an issue on a tired defense: The Commanders made sure the Falcons defense was on the field for the majority of the second half in Sunday’s loss. The Commanders held the ball for 19:42 in the second half, exposing tackling woes that have plagued the Falcons the majority of the year. 

Atlanta missed seven tackles against the run, and part of that was a result of being on the field for 60 plays as the Commanders won the time of possession battle in the second half. Atlanta hasn’t stopped the run all year (21st in the league) and part of the issue is the missed tackles in run-stop situations. 

The Falcons allow 27.9% of first downs via the rush, the third-highest rate in the league. Not good. 

Red zone issues part of another late-game collapses: This collapse can absolutely be blamed on the defense, but let’s not miss the fact Baltimore went 2 of 5 in the red zone in Sunday’s loss to the Jaguars. In goal-to-go situations, Baltimore was 1 of 3 — as Lamar Jackson was only 1 for 4 for 5 yards in those situations. 

The Ravens are 24th in the NFL in red zone offense (51.7%) and 20th in goal-to-go situations (66.7%). Jackson completed just 46.4% of his passes in the red zone, although he has 13 touchdown passes — but only six since Week 4. 

If the Ravens score more touchdowns in the red zone, perhaps the two-score collapses will be less frequent. That was part of the case this week. 

Welcome back, Tre’Davious White: In his first game this season, White played 15 of the Bills’ 67 defensive snaps in the Thanksgiving win over Detroit. The Bills have been waiting for their superstar cornerback to return from his ACL tear, and it finally happened.

In his first game back, White wasn’t even targeted in his seven coverage snaps. He already earned the respect form the Lions offense, even in a game where he was the most vulnerable. 

White’s snaps will increase during the stretch run, and the Bills pass defense could use him for the playoffs. Buffalo’s 19th in pass yards per game allowed and 13th in passing touchdowns allowed, so White is a more-than-welcome addition. 

Brian Burns is one of the elite pass rushers: Plenty in Carolina know how good Burts is, but is play isn’t nearly talked about enough amongst the elite pass rushers in the game. Burns finished with eight pressures, three quarterback hits, and two sacks to lead a Carolina defense that held the Broncos to just three points in the first  57 minutes.

Burns has been terrorizing quarterbacks all season, as the Pro Bowler now has 10 sacks on the year. He also has 53 pressures, 17 quarterback hits, and a 14.8% pressure rate. Burns is fourth in the NFL in pressures and tied for fifth in sacks. He’s one of the elite pass rushers in a game.

Perhaps Carolina not winning is why he isn’t discussed enough amongst the best at his position. 

Offense has to get Chase Claypool going: Claypool had his best game in his short time with the Bears, finishing with two catches for 51 yards in a game where Justin Fields didn’t play. With Darnell Mooney out for an extended period of time (perhaps the rest of the year), it’s time for Claypool to step up. 

The 51 receiving yards amassed his output through his first three games. Claypool only had just 5 catches for 32 yards in his first three games with the Bears (7 catches for 83 yards overall). If the Bears are going to thrive when Fields gets back, they need to focus on Claypool more and get him acclimated to the offense. 

There are two No. 1 wide receivers on this roster: It didn’t take much to convince most people Tee Higgins would step up in the absence of Ja’Marr Chase, but Higgins put up No. 1 wide receiver numbers in the four games Chase missed. Higgins had 26 catches for 371 yards and two touchdowns over the last four games, averaging 14.3 yards per catch. 

He had 16 catches for 262 yards and a touchdown over the last two games (16.4 yards per catch), Chase-like numbers. The Bengals are going to be even more dangerous when Chase returns, knowing opposing defenses will have to stop Higgins too. 

Good luck. 

Jacoby Brissett gives Browns a shot in 2022 with Deshaun Watson returning: A 4-7 start may still be too much to overcome for the Browns to make the playoffs, but their playoff hopes would have been smashed with a loss to the Buccaneers. Brissett wasn’t great in Sunday’s win (23 of 37, 216 yards, touchdown and interception), but he was 8 of 14 for 116 yards with a touchdown in the fourth quarter and overtime (108.0 rating). 

Brissett held down the fort while Watson was suspended, compiling an 89.1 passer rating in the 11 games he played. With the Browns three games out of a playoff spot and six to play, it may be too late. At least Brissett went out a winner and gave them an outside chance. 

The tight ends are more dangerous than they let on: Dalton Schultz looks back to his 2021 self after catching two touchdown passes against the Giants on Thanksgiving. Schultz had his third touchdown in the last three weeks, while having 13 catches for 107 yards in that span. 

Peyton Hendershot also scored a touchdown on a jet sweep, making him a red zone threat if the Cowboys want to go to two tight end sets. This also includes the dangerous running back tandem of Ezekiel Elliott and Tony Pollard to account for. 

The Cowboys have plenty of dangerous red zone targets, but now defenses have to account for the tight ends. Expect them to be utilized more in the coming weeks. 

Patrick Surtain is in a slump: Surtain is one of the best coverage corners in the game, but his last two games have been far from elite. In Sunday’s loss, Surtain was targeted five times and allowed three catches for 77 yards and a touchdown (104.2 rating when targeted). That touchdown was the five-yard pass to Moore. 

The week prior, Surtain allowed five catches for 106 yards and two touchdowns (118.8 rating). These were the only two games Surtain has allowed over an 80 passer rating all year. Surtain has allowed three touchdowns passes the last two weeks (zero the previous eight). 

Surtain is a great cornerback, but he’s struggled of late. 

The Lions have a significant guard problem: Injuries derailed the Lions at guard on Thanksgiving. Detroit had 71 snaps each from Kayode Awosika and Dan Skipper (along with four more from Logan Stenberg). Awosika and Skipper combined to allow four pressures and two sacks, as Jared Goff faced pressure up the middle throughout the game. 

The Bills also had seven tackles for loss and 10 quarterback hits. The Lions were held to 3.4 yards per carry, but that’s expected when the No. 5 and No. 6 guards are starting. Halapoulivaati Vaitai is likely done for the year and Tommy Kraemer has been out since Week 7. Evan Brown (ankle) and Jonah Jackson (concussion) may be back this week, which will help.

Detroit has a good offensive line, but it needs Brown and Jackson back to get back on the winning track. 

Two-minute defense still isn’t good: The Packers have been abysmal on defense in the final two minutes of the first half this season, allowing 60 points in the 12 games played. That’s five points per game. 

The two-minute defense reared its ugly heading Sunday’s loss to the Eagles, as Philadelphia got the ball with 2:16 left and drove nine plays for 66 yards and a touchdown — picking apart Green Bay’s defense in the process. 

Green Bay had the Eagles facing second-and-10 from the Packers’ 30-yard line with 19 seconds left, but Jalen Hurts threw a ball on the money to Quez Watkins — who made a spectacular catch for the touchdown. Hurts was 5 of 6 for 73 yards on the drive and he was sacked twice. 

The Packers just don’t make plays to end the first half — and they ended up losing by four on Sunday. 

Dameon Pierce has hit the rookie wall: The Texans are already the worst team in the NFL, and their offense is nonexistent when Pierce can’t get going. Pierce has 15 carries for 16 yards over the last two games, and the Texans have averaged just 4.5 points over the first three quarters in that stretch. 

Pierce is still a front-runner to win rookie of the year, but opposing defenses know they have to stop him to shut down the Texans. He has 788 rushing yards and four touchdowns, but the yards per carry average slipped to 4.4.

The Texans have to get more creative to free up Pierce in the final six games. Teams are just loading the box now. 

Run defense had another off night: After allowing 141 rushing yards to the Eagles, conventional wisdom suggested the Colts run defense would bounce back against the Steelers. All Pittsburgh did was rush for 172 yards and average 4.8 yards per carry against Indianapolis — a team that had allowed just 3.9 yards per carry on the year. 

Benny Snell didn’t have a carry all year, yet had 12 carries for 62 yards and a touchdown. The Colts held Najee Harris to 35 yards, but still let the Steelers offensive line bully them on the ground. Kenny Pickett generating 32 yards didn’t help matters. 

Quarterbacks that can run definitely hurt the Colts. Dak Prescott may want to make a note of that this week. 

Jacksonville Jaguars

Trevor Lawrence had his best fourth-quarter performance: Lawrence showcased why he’s the franchise quarterback the Jaguars envisioned he was when they took him No. 1 overall. In the fourth quarter against one of the most aggressive defenses in football, Lawrence went 15 of 19 for 173 yards with two touchdowns to zero interceptions and a 139.7 passer rating 

Sunday was just the second time in Jaguars history they won a game when trailing by seven-plus points in the final two minutes of regulation (first since 1996), all thanks to how Lawrence played. He has completed 66.5% of his passes for 2,655 yards with 16 touchdowns and six interceptions (93.6 rating) — all significant improvements over his disastrous rookie year. 

Over the last three games, Lawrence has completed 28 of 36 passes for 272 yards and three touchdowns in the fourth quarter (125.9 rating). The Jaguars quarterback is figuring out how to perform late in games, an excellent sign.

Special teams is the lone weakness: The Chiefs are last in the league in hidden points at a -9.3 (per Football Outsiders), a sign their special teams is getting taken advantage of by opposing field goals, kickoff distance, and punt distance. Kansas City is at a huge disadvantage here, which is probably why the Rams tried a fake punt against Kansas City in Sunday’s game — and converted. 

Teams have tried to take away possessions from Kansas City to keep Patrick Mahomes and the offense off the field. Special teams could cost the Chiefs a Super Bowl appearance. 

Josh Jacobs bails Josh McDaniels out: McDaniels had a questionable decision in overtime to kick a field goal in fourth-and-2 from the Seahawks’ 38-yard line — and Daniel Carlson missed the 56-yard kick. He’s fortunate to get the ball back after Seattle was held to a three-and-out, which set the stage for Jacobs and his 86-yard winning touchdown. 

With how Jacobs played (313 yards of total offense), giving him the ball in a short-yardage situation seemed like a no-brainer. Not for McDaniels, even though a field goal wasn’t winning that game. McDaniels also passed on challenging a Seattle run defense that can’t stop anyone — with arguably the best running back in the league this year. 

How many wins would this team have without Jacobs? 

Los Angeles Chargers

Justin Herbert finally got going running the football: Due to Herbert’s rib cartilage injury, the Chargers quarterback hasn’t been as mobile as he’s been in previous seasons. Herbert rushed for a season-high 38 yards on four carries (9.5 yards per carry), including a 23-yard run that helped set up a final quarter where he finished 13 of 17 for 84 yards and a touchdown — including a two-point conversion that set the Chargers up for a crucial win. 

Herbert had 536 rushing yards and eight touchdowns in his first two seasons, averaging 4.5 yards per carry. This season, he has just 128 yards and no rushing touchdowns (3.6 yards per carry). What makes Herbert dangerous throwing the football is his ability to extend the pocket and make plays, along with taking off in open space.

Herbert may be getting back to his 2021 version with his rib injury improving by the week. 

Tutu Atwell needs to play more: The Rams already have more injuries at wide receiver than they can handle, but it shouldn’t have taken them this long to give Atwell a shot. Atwell had just two catches for 23 yards Sunday, but caught both his targets. 

Atwell isn’t a one-trick pony and isn’t getting the targets he should be getting. With Allen Robinson and Cooper Kupp out, it’s time to give Atwell a fair shot in the passing game — even with that being limited. The Rams are thinking about 2023 anyway, and Atwell could be a valuable piece in that offense. 

Terron Armstead is the key to this offense: Forget how well Tua Tagovailoa is playing, how dominant Tyreek Hill and Jaylen Waddle are, or how efficient the run game is. This offense doesn’t function as efficiently without Armstead — whose addition arguably was the Dolphins’ best offseason move. 

Armstead suffered a pectoral injury late in the first half and didn’t return, significantly altering the pass offense. Tagovailoa was sacked four times in a span of nine plays, but was 2 of 2 for 21 yards in the second half. The Dolphins were wise to pull Tagovailoa when they did, but Armstead is going to be out for a bit. 

The Dolphins will have to survive without their Pro Bowl left tackle, and keep Tagovailoa upright in the process. This offense doesn’t function consistently if QB1 is pressured. 

Kirk Cousins can perform in prime time after all: The Vikings really shut down the “Kirk Cousins can’t play in prime time” narrative, as the quarterback went 30 of 37 for 299 yards with three touchdowns and one interception (116.5 rating) in a win over a Patriots defense that is one of the best in the league. 

Cousins is just 11-18 as a starter in night games in his career, but he avenged the three-interception performance in a Week 2 loss to the Eagles (which was a night game). He still only has an 81.4 passer rating with four touchdowns and four interceptions in two night games this season, but Cousins got rid of some prime time demons in Week 12. 

Uncharacteristic mistakes from a Bill Belichick team: The Patriots’ two-minute drill in the first half had a few mental lapses, starting with Hunter Henry failing to get out of bounds off a 22-yard catch, forcing Belichick to use a timeout. The next mistake happened later in the drive, as Mac Jones slid on a run rather than force an incomplete pass. 

Belichick was fired up having to use another time out and forcing Nick Folk to convert a field goal on third down. Four points may have been taken off the board in a game New England lost by seven. 

Belichick coached teams just don’t make those mental lapses. Very odd to see that from the Patriots. 

The offense may prevent them from winning another game the rest of the year: As if Sunday’s shutout loss to the 49ers wasn’t bad enough, where do the Saints have another win in them? The offense has averaged just 253 yards per game and 12.5 points per game over the last four weeks, numbers no where near good enough to win games in the NFL. 

Sure, three of the Saints’ last six games are against the NFC South — but can anyone really expect New Orleans to compete with these teams knowing how inconsistent the offense is? Alvin Kamara can’t get going and there aren’t many available options at wide receiver outside of Chris Olave. Andy Dalton hasn’t been good either. 

Pete Carmichael’s future may be in doubt if this play keeps up. 

’21 personnel’ needed to help Saquon Barkley: It’s no coincidence Barkley’s slump is coinciding with the Giants’ first losing streak of the year. Barkley has just 26 carries for 61 yards over his last two games, as defenses have certainly zeroed in on stopping him — and the Giants offense in the process.

The Giants are trying to use ’21 personnel’ — or a two-back system — to combat this. Gary Brightwell was the back paired with Barkley in this set, having five carries for 31 yards late in the game. New York has to get more creative on offense to get Barkley going, which hasn’t been a problem until the last few weeks. 

Perhaps more ’21 personnel’ will do the trick. 

Mike White got Elijah Moore going: The key benefit to Mike White starting over Zach Wilson was that the Jets wide receivers could actually play to their talent level. Just ask Elijah Moore, who finished with two catches for 64 yards and a touchdown in Sunday’s win over Chicago. 

Moore’s had a rough season in New York, but Sunday was his highest yardage output of the year. Not a coincidence when White was starting. Prior to last week, Moore had just three catches for 28 yards since Week 5 and had a public disagreement with the franchise. 

Maybe having a quarterback that can get the ball to his receivers will get Moore back to being the player he was in his rookie year. 

Reed Blankenship may be good enough to start: Blankenship was the man the Eagles called upon when C.J. Gardner-Johnson had to leave Sunday’s game with a lacerated kidney, getting the nod over K’Von Wallace in the role. Blankenship picked off Aaron Rodgers, who had a 0.0 passer rating when targeting him (that was Rodgers’ only target his way). 

Blankenship was going 100 miles per hour at skill position players looking to make plays, a different approach than how most defenders play skill position players in the league. His play may be a breath of fresh air for a defense that could use a hard hitter over the next few weeks. 

The Eagles will need to see more of Blankenship, but he proved he’s good enough to start the next week. There aren’t many other options on the roster, at least until Avonte Maddox comes back (if Philadelphia wants to move him out of the slot). 

Kenny Pickett continues to thrive against the blitz: Pickett has a 71.7% completion rate against the blitz, which is the highest among all NFL quarterbacks. In Monday’s win over the Colts, Pickett went 7 of 9 for 69 yards with a 98.6 passer rating, playing mistake free football when defenses send an extra rusher to challenge him. 

Pickett has a 106.9 rating against the blitz without an interception. Not bad for a rookie quarterback with a poor offensive line. The Steelers quarterback has had his struggles, but facing the blitz is not one of them. 

Defense is on another level: Since allowing 44 points to the Chiefs in Week 7, the 49ers defense has allowed 40 points combined. Part of that is players getting healthy, as this unit is scary good. The 49ers allowed just 258.8 yards per game over the last four contests, including just 59.3 rushing yards per game. 

The 49ers rank first in points allowed, yards allowed, passing touchdowns allowed, rushing yards allowed, yards per carry allowed and points per possession. This unit seems to get better by the week too. 

No wonder the 49ers are on a four-game win streak. They’ll be challenged by Miami, but the Dolphins won’t have Terron Armstead. 

The defensive success in midseason was fools gold: Seattle’s defense was torched by the Raiders offense, as Las Vegas amassed 576 yards against the unit (293 passing, 283 rushing). The Seahawks have allowed 497.5 yards per game over the last two games — both losses — and an astonishing 22 rushing yards per game. 

The defense that allowed 282.8 yards per game in the four contests prior to Munich is long gone. Seattle has been gashed on the ground and the defense can’t get off the field on third down (29th in NFL). Seattle won’t make the playoffs if this defense can’t make stops. 

Tom Brady needs to throw to Chris Godwin and Rachaad White more: Brady was a putrid 9 of 22 when he was throwing to pass catchers that weren’t named White or Godwin — and that includes Mike Evans. While caught all nine of his targets for 45 yards while Godwin caught 12 passes (on 13 targets) for 110 yards and a touchdown.

Brady had a 111.2 rating targeting White and Godwin, two players who are producing more in the offense by the week. If the Buccaneers aren’t going to go deep and use a lot of air yards on Brady’s throws, the slot and underneath route to White and Godwin are the ticket.

Get the yards after the catch. 

Shocking red zone performance: The Titans were the No. 2 team in the red zone going into Sunday, but didn’t score a touchdown on any of their three red zone trips in the loss to the Bengals. The Titans have to settle for three field goals, but only got six points (Caleb Shudak missed a field goal). 

In a four-point loss, the failure to convert in the red zone definitely hurt. Derrick Henry had just three carries for seven yards in the red zone, but most importantly — no touchdowns scored. The Titans will have to get this corrected this week against the Eagles, as 16 points won’t be enough to beat a potent offense. 

Based on how the red zone offense has performed, Tennessee should get back on track. 

The stout run defense hits a snag: Washington’s run defense has been excellent over the last several weeks, allowing just 68.8 rushing yards per game over the last five games — a huge reason the Commanders won 4 of 5 heading into Sunday. 

The Falcons are one of the best running teams in the NFL, finishing with 167 yards against a Commanders run defense that allowed just 171 yards total in the three games prior. Washington’s run defense will face Saquon Barkley and the Giants for the next two games, so there’s a cause for concern against one of the top running backs in the league. 

The run defense will be tested over the next two games. 

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High cholesterol: ‘First noticeable’ symptoms include weakness in leg muscles

High cholesterol might be quiet but its presence can lay the groundwork for a slew of complications, ranging from heart disease to stroke. While the fatty culprit rarely shows symptoms, warning signs can appear once cholesterol starts clogging your arteries. One tell-tale sign of this process can present as four unpleasant sensations.

Leaving high cholesterol to its own devices can promote plaque build-up in your arteries.

Apart from cholesterol, plaques are a mix of fatty substances, cellular waste products, calcium as well as fibrin.

Once your arteries house too much of this dangerous cocktail, they become hard and stiff.

This creates less-than-ideal conditions for your blood flow and your legs can take the hit, triggering the “first noticeable” sign.

READ MORE: Acholic stools are ‘the most common’ sign of pancreatic cancer in ‘initial’ stages

This lack of blood flow in your legs can sometimes spur on a “common” condition known as peripheral artery disease (PAD), according to the Cleveland Clinic.

The “first noticeable symptom” triggered by PAD is leg discomfort, pain or cramping.

However, this condition can also trigger four warning sensations in your leg muscles.

According to the health portal, your leg muscles may start feeling:

DON’T MISS 

 

The Cleveland Clinic explains that this warning sign can be severe enough to stop you from participating in your usual daily activities, such as “golfing or chasing after grandchildren”.

Apart from weakness, numbness, heaviness and tiredness in your legs, PAD can also lead to other tell-tale signs, including:

  • A burning or aching pain in your feet and toes while resting, especially at night while lying flat
  • Cool skin on your feet
  • Redness or other colour changes of your skin
  • More frequent infections
  • Toe and foot sores that don’t heal.

Unfortunately, peripheral artery disease doesn’t always cause many noticeable symptoms which makes the condition hard to pick up – similarly to high cholesterol.

Tris tricky nature makes a blood test the most reliable way of determining high cholesterol levels.

Once you get the condition confirmed, there’s plenty you can do to retrieve your levels from the red zone, ranging from a healthy diet to cholesterol-busting medicine called statins.

A cholesterol-lowering food regime requires cutting back on saturated fats – think cheese, butter, sausages and biscuits. However, upping your intake of soluble fibre could also help lower the culprit.

Other helpful lifestyle tweaks include cutting back on alcohol, quitting smoking and picking up exercising.



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Is Muscle Weakness the New Smoking? Grip Strength Tied to Accelerated Biological Age

Summary: Muscle weakness marked by grip strength was associated with accelerated biological aging, a new study reports.

Source: University of Michigan

Everyone ages at a different pace. That’s why two 50-year-olds, despite living the same number of years, may have different biological ages—meaning that a host of intrinsic and extrinsic factors have caused them to age at varying paces with different levels of risk for disease and early death.

Lifestyle choices, such as diet, and smoking, and illness all contribute to accelerating biological age beyond one’s chronological age. In other words, your body is aging faster than expected.

And for the first time, researchers have found that muscle weakness marked by grip strength, a proxy for overall strength capacity, is associated with accelerated biological age.

Specifically, the weaker your grip strength, the older your biological age, according to results published in the Journal of Cachexia, Sarcopenia and Muscle.

Researchers at Michigan Medicine modeled the relationship between biological age and grip strength of 1,274 middle aged and older adults using three “age acceleration clocks” based on DNA methylation, a process that provides a molecular biomarker and estimator of the pace of aging. The clocks were originally modeled from various studies examining diabetes, cardiovascular disease, cancer, physical disability, Alzheimer’s disease, inflammation and early mortality.

Results reveal that both older men and women showed an association between lower grip strength and biological age acceleration across the DNA methylation clocks.

“We’ve known that muscular strength is a predictor of longevity, and that weakness is a powerful indicator of disease and mortality, but for the first time, we have found strong evidence of a biological link between muscle weakness and actual acceleration in biological age,” said Mark Peterson, Ph.D., M.S., lead author of the study and associate professor of physical medicine and rehabilitation at University of Michigan.

“This suggests that if you maintain your muscle strength across the lifespan, you may be able to protect against many common age-related diseases. We know that smoking, for example, can be a powerful predictor of disease and mortality, but now we know that muscle weakness could be the new smoking.”

The real strength of this study was in the 8 to 10 years of observation, in which lower grip strength predicted faster biological aging measured up to a decade later, said Jessica Faul, Ph.D., M.P.H., a co-author of the study and research associate professor at the U-M Institute for Social Research.

Past studies have shown that low grip strength is an extremely strong predictor of adverse health events. One study even found that it is a better predictor of cardiovascular events, such as myocardial infarction, than systolic blood pressure—the clinical hallmark for detecting heart disorders. Peterson and his team have previously shown a robust association between weakness and chronic disease and mortality across populations.

This evidence coupled with their study’s recent findings, Peterson says, shows potential for clinicians to adopt the use of grip strength as a way to screen individuals for future risk of functional decline, chronic disease and even early mortality.

“Screening for grip strength would allow for the opportunity to design interventions to delay or prevent the onset or progression of these adverse ‘age-related’ health events,” he said.

Lifestyle choices, such as diet, and smoking, and illness all contribute to accelerating biological age beyond one’s chronological age. Credit: Justine Ross, Michigan Medicine

“We have been pushing for clinicians to start using grip strength in their clinics and only in geriatrics has this sort of been incorporated. However, not many people are using this, even though we’ve seen hundreds of publications showing that grip strength is a really good measure of health.”

Investigators say future research is needed to understand the connection between grip strength and age acceleration, including how inflammatory conditions contribute to age-related weakness and mortality.

Previous studies have shown that chronic inflammation in aging—known as “inflammaging”—is a significant risk factor for mortality among older adults. This inflammation is also associated with lower grip strength and may be a significant predictor on the pathway between lower grip strength and both disability and chronic disease multimorbidity.

Additionally, Peterson says, studies must focus on how lifestyle and behavioral factors, such as physical activity and diet, can affect grip strength and age acceleration.

“Healthy dietary habits are very important, but I think regular exercise is the most critical thing that somebody can do to preserve health across the lifespan,” he said. “We can show it with a biomarker like DNA methylation age, and we can also test it with a clinical feature like grip strength.”

See also

Additional authors include Stacey Collins, M.A., Helen C.S. Meier, Ph.D., M.P.H., Alexander Brahmsteadt, M.D., all of University of Michigan.

About this aging and muscle strength research news

Author: Noah Fromson
Source: University of Michigan
Contact: Noah Fromson – University of Michigan
Image: The image is credited to Justine Ross, Michigan Medicine

Original Research: Open access.
“Grip strength is inversely associated with DNA methylation age acceleration” by Mark D. Peterson et al. Journal of Cachexia, Sarcopenia and Muscle


Abstract

Grip strength is inversely associated with DNA methylation age acceleration

Background

There is a large body of evidence linking muscular weakness, as determined by low grip strength, to a host of negative ageing-related health outcomes. Given these links, grip strength has been labelled a ‘biomarker of aging’; and yet, the pathways connecting grip strength to negative health consequences are unclear. The objective of this study was to determine whether grip strength was associated with measures of DNA methylation (DNAm) age acceleration.

Methods

Middle age and older adults from the 2006 to 2008 waves of the Health and Retirement Study with 8–10 years of follow-up were included. Cross-sectional and longitudinal regression modelling was performed to examine the association between normalized grip strength (NGS) and three measures of DNAm age acceleration, adjusting for cell composition, sociodemographic variables and smoking. Longitudinal modelling was also completed to examine the association between change in absolute grip strength and DNAm age acceleration. The three DNAm clocks used for estimating age acceleration include the established DunedinPoAm, PhenoAge and GrimAge clocks.

Results

There was a robust and independent cross-sectional association between NGS and DNAm age acceleration for men using the DunedinPoAm (β: −0.36; P < 0.001), PhenoAge (β: −8.27; P = 0.01) and GrimAge (β: −4.56; P = 0.01) clocks and for women using the DunedinPoAm (β: −0.36; P < 0.001) and GrimAge (β: −4.46; P = 0.01) clocks. There was also an independent longitudinal association between baseline NGS and DNAm age acceleration for men (β: −0.26; P < 0.001) and women (β: −0.36; P < 0.001) using the DunedinPoAm clock and for women only using the PhenoAge (β: −8.20; P < 0.001) and GrimAge (β: −5.91; P < 0.001) clocks. Longitudinal modelling revealed a robust association between change in grip strength from wave 1 to wave 3 was independently associated with PhenoAgeAA (β: −0.13; 95% CI: −0.23, −0.03) and GrimAgeAA (β: −0.07; 95% CI: −0.14, −0.01) in men only (both P < 0.05).

Conclusions

Our findings provide some initial evidence of age acceleration among men and women with lower NGS and loss of strength over time. Future research is needed to understand the extent to which DNAm age mediates the association between grip strength and chronic disease, disability and mortality.

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Russia’s air strikes, intended to show force, reveal another weakness

On Monday, Russia fired 84 missiles, many at Ukrainian civilian infrastructure targets, causing power outages in many cities. On Tuesday, Russia launched another 28 cruise missiles. And on Thursday, the Ukrainian Armed Forced General Staff said Russia had hit more than 40 settlements since the day before. In all, more than three dozen people were killed.

But no matter how many times Russia fires at Ukraine, pro-war Russian nationalists want more, even though targeting civilian infrastructure is potentially a war crime.

“It has to be done constantly, not just once but for two to five weeks to totally disable all their infrastructure, all thermal power stations, all heating and power stations, all power plants, all traction substations, all power lines, all railway hubs,” said Bogdan Bezpalko, a member of the Kremlin’s Council on Interethnic Relations.

“Then, Ukraine will descend into cold and darkness,” Bezpalko said on state television. “They won’t be able to bring in ammunition and fuel and then the Ukrainian army will turn into a crowd of armed men with chunks of iron.”

But the hawks, who are demanding publicly on TV broadcasts and on Telegram to know why Russia does not hit more high value targets, won’t like the answer: The Russian military appears to lack sufficient accurate missiles to sustain airstrikes at Monday’s tempo, according to Western military analysts.

“They are low on precision guided missiles,” said Konrad Muzyka, founder of Gdansk, Poland-based Rochan Consulting said, offering his assessment of Russia’s sporadic air attacks. “That is essentially the only explanation that I have.”

Even as NATO allies on Thursday said they would rush additional air defenses to Ukraine, the experts said the reason Russia had yet to knock out electricity and water service across the country was simple: it can’t.

Since May, Russia’s use of precision guided missiles (PGMs) has declined sharply, with analysts suggesting then that Russian stocks of such missiles may be low.

Tuesday’s attacks mainly used air-launched cruise missiles, which are slower than Iskander guided missiles and easier for Ukraine to shoot down, according to Muzyka. In March, the Pentagon reported that Russia’s air-launched cruise missiles have a failure rate of 20 to 60 percent.

“If Russia had a limitless supply of PGMs, I think that they would still strike civilian targets, because that’s what the Russian way of warfare is,” Muzyka said. He said analysts did not have confirmed information about Russian missile stocks or production levels, and judgments were based on the decline in usage of PGMs and Moscow’s greater reliance on less accurate missiles.

At least one person was killed in Zaporizhzhia in a new round of Russian missile attacks across Ukraine on Oct. 11, according to
the State Emergency Service. (Video: The Washington Post)

Putin faces limits of his military power as Ukraine recaptures land

But a clue lies in Russia’s failure to destroy the kinds of targets that Ukraine is able to hit using U.S.-supplied HIMARS artillery.

“If we take a look at what HIMARS has done to Russian supply routes, and essentially their ability to sustain war, they’ve done massive damage to Russia’s posture in this war,” Muzyka said. “So technically, you know, if the Russians had access to a large stock of PGMS, they could probably inflict a similar damage to Ukrainian armed forces, but they haven’t.”

“They actually failed to,” he continued. “They even failed to interdict the main Ukrainian supply roads. They failed to destroy bridges, railway, railway intersections, and so on and so forth.”

Russian President Vladimir Putin is juggling so many military problems that some Western analysts are already predicting Russia’s war will fail. Others say it remains too early to write Russia off, especially with hundreds of thousands of conscripted reinforcements potentially headed to the battlefield in coming weeks.

Since day one, Russia has sustained shocking levels of battlefield casualties, battering military morale. It has suffered repeated defeats, including the failure to take Kyiv, a retreat from Snake Island, the rout in Kharkiv and loss of Lyman, a strategic transit hub.

Ukrainian forces also continue to slowly recover territory in Kherson region, in their ongoing southern offensive.

Russia’s military mobilization also remains in shambles, with angry draftees posting videos online almost daily, complaining of insufficient training and poor equipment. Moscow police raided hostels and cafes on Tuesday to grab men and deliver them to mobilization points, and military recruitment is continuing in Russian prisons, according to independent Russian media site SOTA.

Putin confronted by insider over Ukraine war, U.S. intelligence finds

Lawrence Freedman, professor of war studies at King’s College London, wrote in a newsletter that Russia’s escalation of missile attacks on civilian targets Monday had achieved no clear military gain.

“Russia lacks the missiles to mount attacks of this sort often, as it is running out of stocks and the Ukrainians are claiming a high success rate in intercepting many of those already used,” Freedman wrote. “This is not therefore a new war-winning strategy but a sociopath’s tantrum.”

Putin’s “need to calm his critics also explains why he has lashed out against Ukrainian cities,” Freedman wrote. “The hard-liners have been demanding attacks on Ukrainian infrastructure for some time and they now have got what they wanted. But they will inevitably be disappointed with the results.”

“These attacks could well be repeated, because it is part of the mind-set of Putin and his generals that enemies can be forced to capitulate by such means,” he added. “But stocks of Kalibr and Iskander missiles are running low.”

As missiles strike Ukraine, Israel won’t sell its vaunted air defense

Amid Russia’s military setbacks, striking at Ukraine’s power grid in recent days was designed to shock and terrify civilians, starve them of energy in the winter and break their will to resist, according to Maria Shagina, an analyst with the International Institute for Strategic Studies, a London-based think tank.

Kyiv residents cleared debris from their homes and stores after a Russian missile attack on Oct. 10. (Video: Reuters)

One apparent goal of Russia’s strikes on six electrical substations in Lviv, western Ukraine, was to stop Ukraine exporting electricity to Europe, Shagina said. The strikes also crippled the city’s power supply.

“Now we’re seeing the escalation and weaponization of the critical infrastructure,” she said, adding that it was no accident that Russia had destroyed Ukraine’s capacity to export electricity to Europe at the same time Moscow has weaponized natural gas, cutting supplies to pressure European Union countries.

“There is some intensification of the war, in terms that Russia doesn’t hide even the fact that they have attacked civilian infrastructure, critical infrastructure,” Shagina added. “They’re trying to escalate the war as much as they can.”

Russia’s new commander in Ukraine was decorated after brutality in Syria

Muzyka said Russia, ignoring international conventions, has consistently targeted civilian apartment blocks and infrastructure in two Chechen wars, in Syria and Ukraine.

“Definitely they focus on the power grid as a way of making civilian lives miserable,” he said. “For Russians, striking civilian areas, residential areas and anything that can potentially impact the lives of civilians is a military objective, because for Russia, the war is total.”

“Essentially what the Russians are trying to do is to wear down Ukrainians, decrease the morale, decrease the willingness to fight and from their point of view, hopefully increase the pressure on the Ukrainian government to enter negotiations with Russia,” he added.

Ukraine has asked Western allies for state of the art air defense systems to protect its civilians and vital infrastructure. But even as NATO pledged more help, U.S. Defense Secretary Lloyd Austin said that getting those systems to Ukraine would take time.

“Unfortunately, the Western response is rather limited,” Shagina said, adding that Russia is trying “to use the full range of measures they can deploy against the West and Ukraine.”

But no matter how harsh the attacks, the hawks in Russia say it is still not enough.

Russian journalist Andrei Medvedev, a member of the Moscow city council, who runs a popular hard line nationalist pro-war Telegram channel, urged patience, saying the decision “to bomb Ukraine into the Middle Ages” had not yet been taken.

Another hawk, Alexander Kots, the war correspondent of Komsomolskaya Pravda, who has his own influential pro-war Telegram channel, said he hoped the strikes signaled a new kind of warfare that would bombard Ukraine “until it loses its ability to function.”

Natalia Abbakumova contributed to this report.

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Top Analyst Issues Crypto Warning, Says Bitcoin (BTC) and Ethereum (ETH) Showing Signs of Weakness

A closely followed crypto analyst says that Bitcoin (BTC) and Ethereum (ETH) are flashing signs of weakness despite their respective bounces over the past weeks.

In a new strategy session, DataDash host Nicholas Merten tells his 515,000 YouTube subscribers that’s he’s keeping a close watch on the stock market as it may signal what’s to come for Bitcoin and Ethereum.

According to Merten, the stock market’s recent outperformance of crypto assets could be a hint that Bitcoin’s recent rally doesn’t have much gas left in the tank.

“What is really telling here is how weak crypto has been in comparison to equities markets during this rebound. Equities markets have rebounded a whopping 30%… 

And you would expect that as crypto sells off harder than equities during downtrends, crypto should rebound just as fast and harder to the upside versus equities. We are not seeing this here.

We have seen a month-long period of stagnation. While I don’t mean to speak too bearish here, I got to tell you all, this is starting to showcase some signs of weakness here where, we break below this ascending wedge here with slower growing highs and faster growing lows, it is putting bulls in a very bad position.”

Source: DataDash/YouTube

Looking at Ethereum, the crypto analyst says that ETH is also putting in an underwhelming performance and still hasn’t shown any signs that the bear market is anywhere close to being over.

“Ethereum has been leading the way. The ETH to BTC ratio has continued to garner strength. Take a look here at Ethereum, still only really up about $240 over the past month. I know that that’s still a gain, a nice turn to the upside, a little over 10%… 

It’s not bad, but it’s also not phenomenal. It’s not what I would expect here if we’re really going to get this inflection point…

ETH has made some considerable gains in what is very likely – although I don’t want to speak in absolutes – very likely a long-term extended bear market.”

I

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If You Notice Weakness In Your Legs, Check for Heart Failure— Best Life

Heart failure is a serious chronic condition that occurs when the heart’s muscles can no longer pump blood as they should. Right now, about 6.5 million Americans are living with the potentially fatal disease, the CDC estimates. Though heart failure is a progressive condition which usually becomes worse with time, experts say that it may be possible to reverse some cases with treatment and lifestyle interventions. The first step is recognizing the symptoms of heart failure to identify the problem. Read on to learn one key symptom experts say you may notice in your legs, and how it can cause further complications.

RELATED: Drinking This Daily Can Slash Your Risk of Heart Failure, New Study Says.

Shutterstock

Experts warn that there’s one feeling in your legs you should never ignore when it comes to your heart health. “People with heart failure often have weakness in their leg muscles,” says a 2013 study conducted by UCLA researchers in collaboration with the National Heart, Lung, and Blood Institute (NHLBI).

A separate 2009 study published by the American Heart Association in the journal Circulation: Heart Failure notes that “patients with chronic heart failure (HF) frequently experience skeletal muscle weakness that limits physical function. The mechanisms underlying muscle weakness, however, have not been clearly defined,” the researchers wrote.

RELATED: Not Doing This Before Bed Could Be Hurting Your Heart, Experts Warn.

fizkes / Shutterstock

The Circulation study tested the hypothesis that heart failure leads to leg weakness by changing the “quantity and functionality of the myosin molecule,” a protein that converts chemical energy into mechanical energy, resulting in musculoskeletal movement. Loss of this protein ultimately leads to “muscle weakness and exercise limitation in patients” with heart failure, the study authors believe.

The UCLA researchers add that abnormal activation of the sympathetic nervous system (SNS) is known to occur in people with heart failure, and suggest that this could also contribute to muscle weakness in heart failure patients.

Further research is needed to fully understand why those with heart failure often experience weakness in the legs.

Shutterstock

Those suffering from heart failure are often advised to lose weight as a means of slowing their condition’s progression, notes the UCLA study. “However, many people with heart failure develop weakness in their leg muscles, which can make exercise difficult,” the study authors explain. In some patients, this can create a cycle of weight gain and progressively worsening heart symptoms.

The good news? The Cleveland Clinic has exercise guidelines specifically designed for those with heart failure. They advise starting slowly and gradually increasing your total length of exercise, working out in five to ten minute increments, and trying certain aerobic exercises which take pressure off your legs, among other things.

For more health news sent directly to your inbox, sign up for our daily newsletter. 

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According to the Mayo Clinic, there are several signs of heart failure besides leg weakness that are important to be aware of. These include shortness of breath during exercise or when lying down, fatigue, swelling in the lower extremities, persistent cough or wheezing, swelling of the abdomen, weight gain, nausea, and lack of appetite.

Signs that your heart failure has become an emergency include chest pain, fainting or severe weakness, rapid or irregular heartbeat, severe shortness of breath, or a persistent cough which produces pink foam or mucus.

Speak with your doctor if you notice symptoms of heart failure, and call 911 if you experience emergency symptoms of the condition.

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