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New model says Type 1 diabetes cases worldwide could double by 2040

Using a new model for projecting the number of people with Type 1 diabetes worldwide, members of an international team of researchers estimate up to 17.4 million cases by 2040, double the number of people known to have the disease today.

A study published in the Lancet Diabetes & Endocrinology says 8.4 million people now live with Type 1 diabetes, which occurs when the pancreas produces little or no insulin, leading to a buildup in blood sugar that can be disabling or fatal. Symptoms include excessive thirst and urination, blurred vision, exhaustion, dry skin and unintended weight loss.

Tracking has improved in recent years, but Type 1 diabetes is underrepresented. In addition, because many countries don’t collect Type 1 diabetes data, the numbers have historically skewed toward North America and Europe.

Learning to live with diabetes

To counter the spotty numbers, the researchers created a model that used the available data to predict Type 1 diabetes worldwide.

The estimates counter some myths about the disease, which was once called juvenile diabetes because its onset often occurs during childhood. Yet the majority of people diagnosed with the disease are between ages 20 and 59, and more adults than children are diagnosed each year.

Children, however, are more at risk for death from the disease, especially in low-income countries. A 10-year-old who develops Type 1 diabetes in a low-income country has an average remaining life expectancy of just 13 years vs. 61 years in high-income countries, the researchers write.

About 175,000 people worldwide died because of Type 1 diabetes in 2021, they believe, and 63 to 70 percent of the deaths in those under age 25 occurred because the disease wasn’t diagnosed.

Better data could help that diagnosis rate rise, the researchers say.

“There is an opportunity to save millions of lives in the coming decades,” said Graham Ogle, a University of Sydney Medical School researcher and one of the study’s co-authors, in a news release. The numbers are a warning, he said, that without solutions — such as universal insulin access, a better standard of care and awareness of the symptoms of Type 1 diabetes — the team’s projection will become a reality.

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Multicenter, Randomized Trial of a Bionic Pancreas in Type 1 Diabetes

The authors’ full names and academic degrees are as follows: Steven J. Russell, M.D., Ph.D., Roy W. Beck, M.D., Ph.D., Edward R. Damiano, Ph.D., Firas H. El-Khatib, Ph.D., Katrina J. Ruedy, M.S.P.H., Courtney A. Balliro, R.N., C.D.C.E.S., C.R.N.-B.C., Zoey Li, M.S., Peter Calhoun, Ph.D., R. Paul Wadwa, M.D., Bruce Buckingham, M.D., Keren Zhou, M.D., Mark Daniels, M.D., Philip Raskin, M.D., Perrin C. White, M.D., Jane Lynch, M.D., Jeremy Pettus, M.D., Irl B. Hirsch, M.D., Robin Goland, M.D., John B. Buse, M.D., Ph.D., Davida Kruger, M.S.N., A.P.N.-B.C., B.C.-A.D.M., Nelly Mauras, M.D., Andrew Muir, M.D., Janet B. McGill, M.D., Fran Cogen, M.D., C.D.C.E.S., Jill Weissberg-Benchell, Ph.D., C.D.C.E.S., Jordan S. Sherwood, M.D., Luz E. Castellanos, M.D., Mallory A. Hillard, M.S.N., N.P., A.G.P.C.N.P.-B.C., Marwa Tuffaha, M.D., Melissa S. Putman, M.D., Mollie Y. Sands, M.D., Gregory Forlenza, M.D., Robert Slover, M.D., Laurel H. Messer, Ph.D., R.N., C.D.C.E.S., Erin Cobry, M.D., Viral N. Shah, M.D., Sarit Polsky, M.D., M.P.H., Rayhan Lal, M.D., Laya Ekhlaspour, M.D., Michael S. Hughes, M.D., Marina Basina, M.D., Betul Hatipoglu, M.D., Leann Olansky, M.D., Amrit Bhangoo, M.D., Nikta Forghani, M.D., Himala Kashmiri, M.D., Francoise Sutton, P.N.P., M.S.N., Abha Choudhary, M.D., Jimmy Penn, M.S.N., A.P.R.N., F.N.P.-C., C.D.C.E.S., Rabab Jafri, M.D., Maria Rayas, M.D., Elia Escaname, M.D., Catherine Kerr, M.D., Ruby Favela-Prezas, M.S.N., A.P.R.N., F.N.P.-B.C., Schafer Boeder, M.D., Subbulaxmi Trikudanathan, M.D., Kristen M. Williams, M.D., Natasha Leibel, M.D., M. Sue Kirkman, M.D., Kate Bergamo, F.N.P.-C., Klara R. Klein, M.D., Ph.D., Jean M. Dostou, M.D., Sriram Machineni, M.D., Laura A. Young, M.D., Ph.D., Jamie C. Diner, M.S.N., F.N.P.-C., R.N., C.D.E., Arti Bhan, M.D., J. Kimberly Jones, A.P.N.-B.C., B.C.-A.D.M., Matthew Benson, M.D., Keisha Bird, D.N.P., A.P.R.N., B.C.-A.D.M., Kimberly Englert, R.N., C.C.R.C., Joe Permuy, M.S.N., A.P.R.N., Kristina Cossen, M.D., Eric Felner, M.D., Maamoun Salam, M.D., Julie M. Silverstein, M.D., Samantha Adamson, M.D., Ph.D., Andrea Cedeno, M.D., Seema Meighan, C.P.N.P., and Andrew Dauber, M.D.

The authors’ affiliations are as follows: the Diabetes Research Center, Massachusetts General Hospital (S.J.R., C.A.B., J.S.S., L.E.C., M.A.H., M.T., M.S.P., M.Y.S.), and Boston University (E.R.D.), Boston, and Beta Bionics, Concord (E.R.D., F.H.E.-K.) — all in Massachusetts; the Jaeb Center for Health Research, Tampa (R.W.B., K.J.R., Z.L., P.C.), and Nemours Children’s Health Jacksonville, Jacksonville (N.M., M. Benson, K. Bird, K.E., J. Permuy) — both in Florida; the Barbara Davis Center for Diabetes, University of Colorado, Aurora (R.P.W., G.F., R.S., L.H.M., E.C., V.N.S., S.P.); Stanford University School of Medicine, Palo Alto (B.B., R.L., L.E., M.S.H., M. Basina), Children’s Hospital of Orange County, Orange (M.D., A. Bhangoo, N.F., H.K., F.S.), and the University of California, San Diego, La Jolla (J. Pettus, S.B.) — all in California; Cleveland Clinic, Cleveland (K.Z., B.H., L.O.); University of Texas Southwestern Medical Center, Dallas (P.R., P.C.W., A. Choudhary, J. Penn), and University of Texas Health Science Center, San Antonio (J.L., R.J., M.R., E.E., C.K., R.F.-P.); the University of Washington, Seattle (I.B.H., S.T.); the Naomi Berrie Diabetes Center, Columbia University, New York (R.G., K.M.W., N.L.); the University of North Carolina, Chapel Hill (J.B.B., M.S.K., K. Bergamo, K.R.K., J.M.D., S. Machineni, L.A.Y., J.C.D.); the Henry Ford Health System, Detroit (D.K., A. Bhan, J.K.J.); Emory University, Atlanta (A.M., K.C., E.F.); Washington University in St. Louis, St. Louis (J.B.M., M.S., J.M.S., S.A., A. Cedeno); Children’s National Hospital, Washington, DC (F.C., S. Meighan, A.D.); and the Pritzker Department of Psychiatry and Behavioral Health, Ann and Robert Lurie Children’s Hospital, Chicago (J.W.-B.).

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iOS 16: Make Your iPhone Keyboard Vibrate Whenever You Type

This story is part of Focal Point iPhone 2022, CNET’s collection of news, tips and advice around Apple’s most popular product.

You know that little vibration you feel underneath your finger when you delete an app from your home screen or turn on the flashlight from your lock screen? That’s haptic feedback, and you can now use that feature on your keyboard to enhance typing on the iPhone.

In lieu of those annoying clacking sounds you’re probably used to, haptic feedback provides a silent way to get a more immersive experience when using an iPhone. If you’re a fan of the feature, you’ll be happy to learn that, with the release of iOS 16, haptic feedback integration has spread to some other aspects of your iPhone.

Thanks to iOS 16, you can now get haptic feedback when using your iPhone’s built-in keyboard. Whether you’re sending a text message or drafting an email, every time you hit a key you’ll feel a slight but satisfying vibration, giving the virtual keyboard a bit more of a physical feel.

However, you must manually enable the haptic feedback feature for your keyboard on iOS 16 for this to work. Here’s what you need to know.

If you haven’t yet updated to iOS 16, check out how to download and install iOS 16 right now, seven hidden features we weren’t expecting and all the new features you can look forward to using, like unsending text messages and removing people, pets or objects from your photos.

How to enable haptic feedback to your iPhone keyboard

Before you go through these steps, make sure that your iPhone is updated to iOS 16. You should check out a list of compatible iPhone models and how to go through the installation process.

To enable your keyboard’s haptic feedback:

1. Open the Settings app.

2. Go to Sounds & Haptics.

3. Tap on Keyboard Feedback.

4. Toggle on Haptic.

Toggle this on and you’ll feel a slight vibration each time you tap a key.


Screenshots by Nelson Aguilar/CNET

As soon as haptic feedback is enabled, you’ll feel a slight pulse whenever you tap your keyboard, whether you’re hitting space, entering a character or deleting something. Haptic feedback will run regardless of whether your phone is in silent mode or not.

It’s worth noting that Apple added a note to its support page for haptic feedback that says, “Turning on keyboard haptics might affect the battery life of your iPhone.” 

There is no further explanation, like how much battery the feature may actually consume, but it seems to be a significant enough issue that Apple needed to include a statement about it. If you’re worried about battery life, you may want to keep haptic feedback on the keyboard turned off, especially since going into Low Power Mode does not disable it.

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COVID-19 Linked With Substantial Increase in Type 1 Diabetes in Children – As Much as 72%

According to a new study,children who had COVID-19 are at a substantially higher risk of developing type 1 diabetes.

According to a new research study that analyzed electronic health records of more than 1 million patients ages 18 and younger, children who were infected with

The findings showed a 72% increase in new diagnoses of T1D in COVID-19 patients 18 years old and younger—although the research emphasized that it is unclear whether COVID-19 triggers new onset of T1D.

Type 1 diabetes was previously known as insulin-dependent or juvenile diabetes. Although it usually develops in children, teens, and young adults, it can happen at any age. Type 1 diabetes is much less common than type 2. In fact, only about 5-10% of people with diabetes have type 1. Currently, no one knows how to prevent type 1 diabetes, but it can be treated successfully.

Nationally, approximately 187,000 children and adolescents younger than 20 live with T1D, according to the Centers for Disease Control and Prevention (CDC).

“Type 1 diabetes is considered an autoimmune disease,” said Pamela Davis. She is a corresponding author on the study and Distinguished University Professor and The Arline H. and Curtis F. Garvin Research Professor at the Case Western Reserve School of Medicine. “It occurs mostly because the body’s immune defenses attack the cells that produce insulin, thereby stopping insulin production and causing the disease. COVID has been suggested to increase autoimmune responses, and our present finding reinforces that suggestion.”

The team of researchers analyzed the de-identified electronic health records of nearly 1.1 million patients aged 18 years and younger diagnosed with the

Rong Xu, also a corresponding author, is a professor of Biomedical Informatics at the School of Medicine and director of the Center for Artificial Intelligence in Drug Discovery. She said further research is needed to investigate if the increased risk of new onset T1D following SARS-CoV2 infection in pediatric patients will persist, who are vulnerable, and how to treat COVID-19 associated T1D in children.

“We are also investigating possible changes in development of type 2 diabetes in children following SARS-CoV2 infection,” Xu said.

T1D is most common in children while type 2 diabetes (T2D) is known as “adult-onset diabetes” and develops over time, often as the patient becomes resistant to the effects of insulin and later, as the pancreas stops making enough insulin, according to the CDC.

Reference: “Association of SARS-CoV-2 Infection With New-Onset Type 1 Diabetes Among Pediatric Patients From 2020 to 2021” by Ellen K. Kendall, BA; Veronica R. Olaker, BS; David C. Kaelber, MD, PhD; Rong Xu, PhD and Pamela B. Davis, MD, PhD, 23 September 2022, JAMA Network Open.
DOI: 10.1001/jamanetworkopen.2022.33014

The Case Western Reserve research team also included David Kaelber, professor of Internal Medicine, Pediatrics and Population and Quantitative Health Sciences, and medical students Ellen Kendall and Veronica Olaker.



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COVID-19 Associated With Increase in New Diagnoses of Type 1 Diabetes in Youth, by as Much as 72%

Summary: Children who contracted COVID-19 are at increased risk of being diagnosed with Type 1 diabetes. Researchers found a 72% increase in new Type 1 diabetes cases in those under 18 who contracted COVID-19.

Source: Case Western Reserve

Children who were infected with COVID-19 show a substantially higher risk of developing type 1 diabetes (T1D), according to a new study that analyzed electronic health records of more than 1 million patients ages 18 and younger.

In a study published today in the journal JAMA Network Open, researchers at the Case Western Reserve University School of Medicine report that children and adolescents who contracted COVID-19 were more prone to developing T1D in the six months following their COVID diagnosis.

The findings showed a 72% increase in new diagnoses of T1D in COVID-19 patients 18 years old and younger—although the research emphasized that it is unclear whether COVID-19 triggers new onset of T1D.

About 187,000 children and adolescents younger than 20 live with T1D nationally, according to the Centers for Disease Control and Prevention (CDC).

“Type 1 diabetes is considered an autoimmune disease,” said Pamela Davis, Distinguished University Professor and The Arline H. and Curtis F. Garvin Research Professor at the Case Western Reserve School of Medicine, a study corresponding author.

“It occurs mostly because the body’s immune defenses attack the cells that produce insulin, thereby stopping insulin production and causing the disease. COVID has been suggested to increase autoimmune responses, and our present finding reinforces that suggestion.”

The team analyzed the de-identified electronic health records of nearly 1.1 million patients age 18 years and younger in the United States and 13 other countries diagnosed with the SARS-CoV-2 infection between March 2020 and December 2021 and also those diagnosed with a non-COVID-related respiratory infection during that same period.

The study population was further divided into two groups: patients up to age 9 years and those age 10–18 years. After careful statistical matching to account for age, demographics and family history of diabetes, there were 285,628 in each group for a total of 571,256 patients.

Study findings

The research team found that among the more than 571,000 pediatric patients:

  • Within six months of SARS-CoV2 infection, 123 patients (0.043%) had received a new diagnosis of T1D, compared to 72 patients (0.025%) who received a new diagnosis following a non-COVID respiratory infection, an increase of 72% in new diagnoses.
  • At one, three and six months following infection, the risk of diagnosis of T1D was substantially greater for those infected with SARS-CoV2 compared to those with non-COVID respiratory infections. Similar results were reported with patients in the infant-9-year-old and 10- to 18-year-old age groups.

“Families with high risk of type 1 diabetes in their children should be especially alert for symptoms of diabetes following COVID, and pediatricians should be alert for an influx of new cases of type 1 diabetes, especially since the Omicron variant of COVID spreads so rapidly among children,” Davis said.

The findings showed a 72% increase in new diagnoses of T1D in COVID-19 patients 18 years old and younger—although the research emphasized that it is unclear whether COVID-19 triggers new onset of T1D. Image is in the public domain

“We may see a substantial increase in this disease in the coming months to years. Type 1 diabetes is a lifelong challenge for those who have it, and increased incidence represents substantial numbers of children afflicted.”

See also

Rong Xu, also a corresponding author, professor of Biomedical Informatics at the School of Medicine and director of the Center for Artificial Intelligence in Drug Discovery, said further research is needed to examine if the increased risk of new onset T1D following SARS-CoV2 infection in pediatric patients will persist, who are vulnerable, and how to treat COVID-19 associated T1D in children.

“We are also investigating possible changes in development of type 2 diabetes in children following SARS-CoV2 infection,” Xu said.

T1D is most common in children while type 2 diabetes (T2D) is known as “adult-onset diabetes” and develops over time, often as the patient becomes resistant to the effects of insulin and later, as the pancreas stops making enough insulin, according to the CDC.

The Case Western Reserve research team also included David Kaelber, professor of Internal Medicine, Pediatrics and Population and Quantitative Health Sciences, and medical students Ellen Kendall and Veronica Olaker.

Previous COVID-related studies led by the CWRU team have found that the risk factor for Alzheimer’s disease increases by 50–80% in older adults who caught COVID and that people with dementia are twice as likely to contract COVID.

About this COVID-19 and diabetes research news

Author: Press Office
Source: Case Western Reserve
Contact: Press Office – Case Western Reserve
Image: The image is in the public domain

Original Research: The findings will appear in JAMA Network Open

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Even SLIM type 2 diabetics can reverse their condition

Even SLIM type 2 diabetics can reverse their condition with ‘game-changing’ soup and shake diet: Top experts say patients just need to lose 10% of their body weight

  • This is the equivalent of someone with a 13st (83kg) frame losing 1st 4lbs (8kg) 
  • Newcastle Uni scientists presented findings at a medical conference in Sweden
  • They said findings support the idea that everyone has a ‘personal fat threshold’ 

Even slim people with type 2 diabetes can reverse their condition through a soup and shakes diet, researchers revealed today.

And they only need to lose 10 per cent of their body weight, experts believe. 

This is the equivalent of someone with a 13st (83kg) frame losing 1st 4lbs (8kg). 

Newcastle University scientists say the findings, presented at a medical conference in Sweden, support the idea that everyone has a ‘personal fat threshold’. 

Type 2 diabetes affects roughly 4.5million people in Britain and 37million in the US. Although heavily driven by obesity, roughly 15 per cent of all sufferers are of ‘normal weight’ (stock)

Professor Roy Taylor, a world renowned diabetes expert and lead researcher, said: ‘If you develop type 2 diabetes, you simply have more fat inside your body than you can cope with, even if apparently slim.

‘This excess fat spills into your liver and pancreas stopping normal function and causing type 2 diabetes. 

‘You only need an extra half gram of fat in the pancreas to prevent normal insulin production.

‘I’m often asked, “Why have I got type 2 diabetes when all my friends are larger than me and do not have diabetes?” The present work answers this conundrum.’ 

Type 2 diabetes occurs when the body doesn’t make enough insulin, or if the insulin it makes doesn’t work properly — leading to high blood sugar levels.

What IS type 2 diabetes? 

Type 2 diabetes is a condition which causes a person’s blood sugar to get too high.

More than 4million people in the UK are thought to have some form of diabetes.

Type 2 diabetes is associated with being overweight and you may be more likely to get it if it’s in the family.

The condition means the body does not react properly to insulin – the hormone which controls absorption of sugar into the blood – and cannot properly regulate sugar glucose levels in the blood.

Excess fat in the liver increases the risk of developing type 2 diabetes as the buildup makes it harder to control glucose levels, and also makes the body more resistant to insulin.

Weight loss is the key to reducing liver fat and getting symptoms under control.

Symptoms include tiredness, feeling thirsty, and frequent urination.

It can lead to more serious problems with nerves, vision and the heart.

Treatment usually involves changing your diet and lifestyle, but more serious cases may require medication.

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Uncontrolled diabetes can lead to blindness and leave patients needing their limbs amputated or in a coma.

It affects roughly 4.5million people in Britain and 37million in the US. 

Although heavily driven by obesity, roughly 15 per cent of all sufferers are of ‘normal weight’. 

This puts them in the group known as TOFIs – who are ‘thin on the outside and fat on the inside’. 

TOFIs are not usually advised to lose weight, with doctors under the belief that their condition has another cause. 

But the new findings prove that guidance — which has been pushed out for years — is wrong.

Twenty participants were recruited for the study. They had an average BMI of 24.8 — defined as a ‘healthy’ weight.

All of the volunteers were asked to stick to a daily 800 calorie regime for a fortnight, consisting of low-calorie shakes and soups.

A similar diet, labelled ‘game-changing’, has been shown to help overweight type 2 diabetics reverse their condition. The results have even seen NHS doctors prescribe soup and shakes to help obese Britons slim down.

Participants were then allowed to ditch the soups and shakes but eat sensibly for up to six weeks, so they didn’t pile on the pounds again.

The cycle was repeated up to three times, until they lost at least 10 per cent of their body weight.

Fourteen volunteers went into remission, allowing them to ditch all their medication.

Reversal was defined as blood sugar levels staying below the technical threshold for diabetes for at least six months.

Their average BMI fell to 22.4.

Meanwhile, MRI scans showed levels of fat inside their liver and pancreas had fallen ‘substantially’.

The findings were presented at the European Association for the Study of Diabetes (EASD) in Stockholm.

Marathon runner who was diagnosed with diabetes is now in remission after soups and shakes diet 

Having recently run his first marathon, David Childs seemed an unlikely candidate for type 2 diabetes.

But he was diagnosed in June 2020 after suffering severe daily headaches and fainting, because his blood sugar had become too high.

Having recently run his first marathon, David Childs seemed an unlikely candidate for type 2 diabetes. But he was diagnosed in June 2020 after suffering severe daily headaches and fainting, because his blood sugar had become too high

Mr Childs, 48, signed up to the ReTUNE trial to reverse type 2 diabetes last March, as one of around 10 per cent of people with the condition who are a healthy weight.

The father-of-four, from the village of Cleadon in South Tyneside, said: ‘Even my GP did not believe I had type 2 diabetes at first.

‘I don’t have a family history of diabetes, I am slim, and I had recently run a marathon, after several half-marathons.

‘But unfortunately, while I didn’t have a beer belly, I did have excess fat in my liver.

‘I was determined to get off the tablets I had been given and reverse it if I could.’

Mr Childs completed two month-long diets of meal-replacement soups and shakes to lose around 10 per cent of his body weight.

That brought the 48-year-old, who is five feet 11ins tall, down to a weight of 82kg (12 stones and 13 pounds).

Mr Childs, who works for a pharmaceutical company, achieved remission from diabetes halfway through the trial and has not looked back.

He runs twice a week, tries to eat healthily and has reduced his consumption of crisps and bread.

He said: ‘I was worried my future entailed slowly increasing my medication, and being at risk of health problems from diabetes.

‘Now every morning I still prick my finger to check my blood sugar and, every time I see it is normal, I smile to myself that I don’t have diabetes any more.’

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Glycemia Reduction in Type 2 Diabetes — Glycemic Outcomes

Supported by a grant (U01DK098246) from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) of the National Institutes of Health (NIH); a U34 planning grant (U34-DK-088043) for the planning of the trial from the NIDDK; funding for the initial planning meeting regarding the U34 proposal from the American Diabetes Association; the National Heart, Lung, and Blood Institute; the Centers for Disease Control and Prevention; resources and facilities from the Department of Veterans Affairs; grants (P30 DK017047, P30 DK020541-44, P30 DK020572, P30 DK072476, P30 DK079626, P30 DK092926, U54 GM104940, UL1 TR000170, UL1 TR000439, UL1 TR000445, UL1 TR001102, UL1 TR001108, UL1 TR001409, 2UL1TR001425, UL1 TR001449, UL1 TR002243, UL1 TR002345, UL1 TR002378, UL1 TR002489, UL1 TR002529, UL1 TR002535, UL1 TR002537, UL1 TR002541, and UL1 TR002548) from the NIH; educational materials from the National Diabetes Education Program; and donated medications and supplies from Becton Dickinson, Bristol Myers Squibb, Merck , Novo Nordisk, Roche Diagnostics, and Sanofi.

Disclosure forms provided by the authors are available with the full text of this article at NEJM.org.

The members of the writing committee (David M. Nathan, M.D., John M. Lachin, Sc.D., Ashok Balasubramanyam, M.D., Henry B. Burch, M.D., John B. Buse, M.D., Nicole M. Butera, Ph.D., Robert M. Cohen, M.D., Jill P. Crandall, M.D., Steven E. Kahn, M.B., Ch.B., Heidi Krause-Steinrauf, M.S., Mary E. Larkin, R.N., Neda Rasouli, M.D., Margaret Tiktin, D.N.P., Deborah J. Wexler, M.D., and Naji Younes, Ph.D.) assume responsibility for the overall content and integrity of this article.

The content of this article is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.

A data sharing statement provided by the authors is available with the full text of this article at NEJM.org.

We thank the participants, whose loyal dedication made this trial possible.

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5 Unexpected Reasons You Get So Many Mosquito Bites: Blood Type, Clothing and More

While summer is by far my favorite season, fall is a close second. The moderate temperatures and decreased humidity means I can spend more time outside doing things I love: hiking, walking and spending time at the lake. But that time in nature is promptly spoiled when I find myself covered in red, itchy lumps after spending just a few minutes outdoors. Because even though fall is almost here, pesky mosquitos are still active until early November. 

If you’re like me, you get frustrated by the number of mosquito bites that appear all over your body, making you feel like scratching the skin around the bite until you reach bone. While the bites alone can be annoying, it’s just downright infuriating when I come inside sporting several new bright-red welts while my friends so kindly report how they don’t have a single one. 

Why is that? It’s not that we’re particularly unlucky. There are actually scientific reasons why mosquitoes single out certain people. Here’s exactly why mosquitoes bite, and how you can make yourself less of a target this season and beyond. (You can also find out how to easily remove ticks without tweezers.)

Why do mosquitoes bite?

Contrary to what you might think, mosquitoes don’t bite people for food — they feed on plant nectar. Only female mosquitoes bite, and they do so to receive proteins from your blood needed to develop their eggs. 

Why are some people more prone to bites?

There are several factors that impact why some people are more prone to mosquito bites than others:

Blood type

A common belief is that mosquitoes are attracted to certain blood types, considering mosquitoes bite humans for their blood. Blood type is determined by genetics, and each blood type is created based on the different sets of specific proteins, called antigens, on the surface of red blood cells. There are four main blood types: A, B, AB and O. 

While there are no firm conclusions as to which blood type is more attractive to mosquitoes, several studies have suggested people with type O are most appetizing to mosquitoes. A 2019 study observed mosquito feeding behavior when presented with different blood type samples, and found mosquitoes fed from the type O feeder more than any other. A 2004 study also found that mosquitoes land on blood group O secretors (83.3%) significantly more than group A secretors (46.5%).

However, these studies are not definitive, and much is still up in the air about mosquito preferences when it comes to blood type.

Clothing color 

Mosquitoes are highly visual hunters when it comes to finding a human to bite. This means movement and dark clothing colors like black, navy and red can stand out to a mosquito. Research has shown that mosquitoes are more attracted to the color black, but there has been little additional research into why this is the case. 

Carbon dioxide

Mosquitoes use sight and smell to find hosts to bite. One of the quickest ways mosquitoes can sniff out a person is through the carbon dioxide emitted when we breathe. According to research published in the journal Chemical Senses, mosquitoes use an organ called a maxillary palp for carbon dioxide detection and can sense it from 164 feet away. 

Because carbon dioxide is a huge attractor, people who emit more of it — larger individuals and people who are breathing heavily when working out — are more attractive to a mosquito. 

Body odor and sweat

Mosquitoes are attracted to more substances and compounds than just carbon dioxide. Mosquitoes can find people to bite by smelling substances present on human skin and in sweat, including lactic acid, uric acid and ammonia. 

Researchers are still learning why certain body odors are more attractive to mosquitoes, but they do know that genetics, bacteria on the skin and exercise all play a factor. Genetics impact the amount of uric acid emitted, while exercise increases lactic acid buildup. 

Beer

In a small study, mosquitoes were observed to land on participants more frequently after they had drunk a small amount of beer. But before you swear off beer for good, know that the study only had 14 participants, and it found that mosquitoes may only be marginally more attracted to people who have been drinking beer.

The size and severity of a bite relate to how your immune system responds to the saliva introduced by the mosquito when it bites.


Suriyawut Suriya/EyeEm/Getty Images

Why do some people swell from mosquito bites more than others?

Mosquito bites can range in size from small little spots to large welts. Why is this the case?

Bites affect people differently. The size and severity of a bite relate to how your immune system responds to the saliva introduced by the mosquito when it bites. When mosquitoes bite, they inject some saliva when drawing blood. This saliva contains certain anticoagulants and proteins, triggering the immune system to respond to these foreign substances. 

Our body responds by releasing histamine — a chemical that is released by white blood cells when your immune system is fighting against allergens — which causes the itchiness and inflammation of the bite. 

Prevention and treatment of mosquito bites

The best way to handle a mosquito bite is to not get them in the first place — but often times, that’s easier said than done. 

Some common ways to prevent mosquito bites include:

  • Use repellents and bug sprays (Repel, Off! Deep Woods, and other brands that contain DEET)
  • Use natural repellants (citronella essential oil, neem oil, thyme essential oil)
  • Avoid going outside at dawn or dusk 
  • Avoid dark-colored clothing, specifically black
  • Avoid standing water and try to eliminate standing water near your home
  • Use mosquito netting when camping or sleeping outdoors

Repellants are highly effective in preventing mosquito bites. 


Amanda Capritto/CNET

Mosquito bites, while annoying, are often not severe and will resolve in a few days. In the meantime, there are several treatments to alleviate the itchiness and inflammation:

  • Clean with rubbing alcohol if a fresh bite
  • Take an oatmeal bath 
  • Use over-the-counter antihistamines such as Benadryl or Claritin
  • Apply mild corticosteroid creams
  • Use aloe vera to reduce inflammation
  • Try a cold compress

Though difficult, try as best you can to not itch the bite too roughly to prevent any sort of skin reaction or infection. 

For more, read about the five smart ways to repel mosquitoes this summer, the mosquito forecast tool launched by Google and Off, and how you can make your own DIY traps for mosquitoes, hornets and other flying pests.

The information contained in this article is for educational and informational purposes only and is not intended as health or medical advice. Always consult a physician or other qualified health provider regarding any questions you may have about a medical condition or health objectives.

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Drink More Tea To Reduce the Risk of Developing Type 2 Diabetes

According to a systematic review and meta-analysis of studies including over a million people, four or more cups of black, green, or oolong tea every day is linked to a 17% lower risk of developing type 2 diabetes.

Drinking plenty of tea may reduce the risk of developing type 2 diabetes, finds a study on over a million adults.

Four or more cups of black, green, or oolong tea every day is linked to a 17% lower risk of developing type 2 diabetes.

Moderate consumption of black, green, or Oolong tea is linked to a lower risk of developing type 2 diabetes (T2D), according to the results of a systematic review and meta-analysis of 19 cohort studies involving more than 1 million adults from eight countries.

The findings suggest that drinking at least four cups of tea a day is associated with a 17% lower risk of T2D over an average period of 10 years. The study will be presented at this year’s European Association for the Study of Diabetes (EASD) Annual Meeting in Stockholm, Sweden (September 19-23).

“Our results are exciting because they suggest that people can do something as simple as drinking four cups of tea a day to potentially lessen their risk of developing type 2 diabetes,” says lead author Xiaying Li from Wuhan University of Science and Technology in China.

Tea contains various antioxidant, anti-inflammatory, and anticarcinogenic compounds tea. While it’s long been known that regularly drinking tea may be beneficial for health due to those properties, less clear has been the relationship between tea drinking and the risk of T2D. Published cohort studies and meta-analyses thus far have reported inconsistent findings.

To address this uncertainty, investigators conducted a cohort study and a dose-response meta-analysis to better define the relationship between tea consumption and  future risk of T2D.

When compared with adults who didn’t drink tea, those who drank 1-3 cups every day lowered their risk of T2D by 4%. More impressively, those who consumed at least 4 cups daily reduced their risk by 17%.

First, they studied 5,199 adults (2583 men, 2616 women) with an average age of 42 and no history of T2D from the China Health and Nutrition Survey (CHNS), who were recruited in 1997 and followed until 2009. The CHNS is a multicenter prospective study looking at the economics, sociological issues, and health of residents from nine provinces.

At the outset, participants filled in a food and drink frequency questionnaire. They also provided information on lifestyle factors such as regular exercise, smoking, and alcohol consumption. Overall, 2,379 (46%) participants reported drinking tea. By the end of the study, 522 (10%) participants had developed T2D.

Researchers found that tea drinkers had a similar risk of developing T2D compared to non-drinkers after adjusting for factors that are known to be linked with increased risk of T2D, like age, sex, and physical inactivity. Additionally, the results did not change significantly when analyzed by age and sex, or when participants who developed diabetes during the first 3 years of follow-up were excluded.

In the next step of the study, the scientists did a systematic review of all cohort studies investigating tea drinking and the risk of T2D in adults (aged 18 or older) up to September 2021. Overall, 19 cohort studies involving 1,076,311 participants from eight countries (China, the USA, Finland, Japan, the UK, Singapore, the Netherlands, and France) were included in the dose-response meta-analysis.

They explored the potential impact on the risk of T2D of different types of tea (green tea, oolong tea, and black tea), frequency of tea drinking (less than 1 cup/day, 1-3 cups/day, and 4 or more cups/day), sex (male and female), and the location of the study (Europe and America, or Asia).

Overall, the meta-analysis found a linear association between tea drinking and T2D risk, with each cup of tea consumed per day reducing the risk of developing T2D by around 1%.

When compared with adults who didn’t drink tea, those who drank 1-3 cups daily lowered their risk of T2D by 4%. More impressively, those who consumed at least 4 cups every day reduced their risk by 17%.

The associations were maintained regardless of the type of tea participants drank, whether they were male or female, or where they lived. This suggests that it may be the amount of tea consumed, rather than any other factor, that plays a major role.

“While more research needs to be done to determine the exact dosage and mechanisms behind these observations, our findings suggest that drinking tea is beneficial in reducing the risk of type 2 diabetes, but only at high doses (at least 4 cups a day)”, says Li.

She adds, “It is possible that particular components in tea, such as polyphenols, may reduce blood glucose levels, but a sufficient amount of these bioactive compounds may be needed to be effective. It may also explain why we did not find an association between tea drinking and type 2 diabetes in our cohort study, because we did not look at higher tea consumption.”

Oolong tea is a traditional Chinese tea that’s made from the same plant used to make green and black teas. The difference is how the tea is processed—green tea is not allowed to oxidize much, black tea is allowed to oxidize until it turns black, and oolong tea is partially oxidized.

Despite the important findings, the authors note that the study is observational. Therefore it cannot prove that drinking tea is the cause of the reduced the risk of T2D, even though suggests that it is a likely contributor.

Additionally, the research team point to several caveats, including that they relied on subjective assessments of the quantities of tea consumed and they cannot rule out the possibility that residual confounding by other lifestyle and physiological factors may have affected the results.

The study was funded by the Young Talents Project of Hubei Provincial Health Commission, China; Science and Technology Research Key Project of Education Department of Hubei Province, China; Sanuo Diabetes Charity Foundation, China; and Xiangyang Science and Technology Plan Project, China.



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Drinking Plenty of Tea May Reduce the Risk of Developing Type 2 Diabetes

Summary: Drinking four or more cups of black, green, or oolong tea daily was associated with a 17% lower risk of developing Type 2 diabetes.

Source: Diabetologia

A systematic review and meta-analysis of 19 cohort studies involving more than 1 million adults from eight countries finds that moderate consumption of black, green or Oolong tea is linked to a lower risk of developing type 2 diabetes.

The findings, being presented at this year’s European Association for the Study of Diabetes (EASD) Annual Meeting in Stockholm, Sweden (19-23 Sept), suggest that drinking at least four cups of tea a day is associated with a 17% lower risk of T2D over an average period of 10 years.

“Our results are exciting because they suggest that people can do something as simple as drinking four cups of tea a day to potentially lessen their risk of developing type 2 diabetes”, says lead author Xiaying Li from Wuhan University of Science and Technology in China.

While it’s long been known that regularly drinking tea may be beneficial for health because of the various antioxidant, anti-inflammatory and anticarcinogenic compounds tea contains, less clear has been the relationship between tea drinking and the risk of T2D. So far, published cohort studies and meta-analyses have reported inconsistent findings.

To address this uncertainty, researchers conducted a cohort study and a dose-response meta-analysis to better define the relationship between tea consumption and future T2DM risk.

First, they studied 5,199 adults (2583 men, 2616 women) with no history of T2D (average age 42) from the China Health and Nutrition Survey (CHNS), who were recruited in 1997 and followed until 2009. The CHNS is a multicentre prospective study looking at the economics, sociological issues and health of residents from nine provinces.

At the outset, participants filled in a food and drink frequency questionnaire and provided information on lifestyle factors such as regular exercise, smoking and alcohol consumption. Overall, 2,379 (46%) participants reported drinking tea, and by the end of the study, 522 (10%) participants had developed T2D.

After adjusting for factors that are known to be linked with increased risk of T2D, like age, sex, and physical inactivity, researchers found that tea drinkers had a similar risk of developing T2D compared to non-drinkers. And the results did not change significantly when analysed by age and sex, or when participants who developed diabetes during the first 3 years of follow-up were excluded.

In the next step of the study, the researchers did a systematic review of all cohort studies investigating tea drinking and the risk of T2D in adults (aged 18 or older) up to September 2021. Overall, 19 cohort studies involving 1,076,311 participants from eight countries [1] were included in the dose-response meta-analysis.

They explored the potential impact of different types of tea (green tea, oolong tea, and black tea), frequency of tea drinking (less than 1 cup/day, 1-3 cups/day, and 4 or more cups/day), sex (male and female), and the location of the study (Europe and America, or Asia), on the risk of T2D.

Overall, the meta-analysis found a linear association between tea drinking and T2D risk, with each cup of tea consumed per day reducing the risk of developing T2D by around 1%.

When compared with adults who didn’t drink tea, those who drank 1-3 cups daily lowered their risk of T2D by 4%, while those who consumed at least 4 cups every day reduced their risk by 17%.

Overall, the meta-analysis found a linear association between tea drinking and T2D risk, with each cup of tea consumed per day reducing the risk of developing T2D by around 1%. Image is in the public domain

The associations were observed regardless of the type of tea participants drank, whether they were male or female, or where they lived, suggesting that it may be the amount of tea consumed, rather than any other factor, that plays a major role.

See also

“While more research needs to be done to determine the exact dosage and mechanisms behind these observations, our findings suggest that drinking tea is beneficial in reducing the risk of type 2 diabetes, but only at high doses (at least 4 cups a day)”, says Li.

She adds, “It is possible that particular components in tea, such as polyphenols, may reduce blood glucose levels, but a sufficient amount of these bioactive compounds may be needed to be effective. It may also explain why we did not find an association between tea drinking and type 2 diabetes in our cohort study, because we did not look at higher tea consumption.”

Oolong tea is a traditional Chinese tea that’s made from the same plant used to make green and black teas. The difference is how the tea is processed—green tea is not allowed to oxidise much, black tea is allowed to oxidise until it turns black, and oolong tea is partially oxidised.

Despite the important findings, the authors note that the study is observational and cannot prove that drinking tea reduced the risk of T2D, but suggests that it is likely to contribute.

And the researchers point to several caveats, including that they relied on subjective assessments of the quantities of tea consumed and they cannot rule out the possibility that residual confounding by other lifestyle and physiological factors may have affected the results.

About this diabetes research news

Author: Judy Naylor
Source: Diabetologia
Contact: Judy Naylor – Diabetologia
Image: The image is in the public domain

Original Research: The findings will be presented at The European Association for the Study of Diabetes Annual Meeting

Read original article here

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