Tag Archives: strains

No foul play suspected after college student Riley Strain’s body is found in a Nashville river, police say – CNN

  1. No foul play suspected after college student Riley Strain’s body is found in a Nashville river, police say CNN
  2. Riley Strain’s body found in Cumberland River in Nashville, police say USA TODAY
  3. Riley Strain vigil: Nashville mourns after Missouri student’s body found in Cumberland River Tennessean
  4. Springfield native Riley Strain’s body found in Tennessee river after nearly 2-week search; family shares their gratitude KY3
  5. Mayor suggests barriers for Nashville’s entertainment district after Riley Strain’s body recovered from river WSMV 4

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‘We’re becoming overwhelmed’: Spike in patients seeking ER, Urgent Care strains resources amid RSV hospitalizations – NBC 5 Dallas-Fort Worth

  1. ‘We’re becoming overwhelmed’: Spike in patients seeking ER, Urgent Care strains resources amid RSV hospitalizations NBC 5 Dallas-Fort Worth
  2. Cook Children’s is full amid wave of RSV infections The Dallas Morning News
  3. Emergency rooms seeing uptick in infant, young children RSV cases Atlanta News First
  4. ‘We are becoming overwhelmed’: North Texas hospitals see sharp increase in RSV cases WFAA.com
  5. Cook Children’s ER in Fort Worth seeing 500 patients a day as RSV, flu cases surge Fort Worth Star-Telegram
  6. View Full Coverage on Google News

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Don’t give up on us: Lapid urges US Jews to stand by Israel despite overhaul strains – The Times of Israel

  1. Don’t give up on us: Lapid urges US Jews to stand by Israel despite overhaul strains The Times of Israel
  2. Netanyahu cancels Tel Aviv Jewish conference appearance amid protests: Local media Anadolu Agency | English
  3. PM drums up support for right-wing ‘million person’ rally, but won’t join – report The Times of Israel
  4. Protest leaders take the stage at JFNA, say overhaul is ‘tearing up social contract’ The Times of Israel
  5. Organizers warn they will kick out any protesters disrupting JFNA confab The Times of Israel
  6. View Full Coverage on Google News

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Flu vaccine appears to be a very good match to circulating strains, CDC says

This year’s flu shot appears to be “a very good match” to the circulating strains, U.S. Centers for Disease Control and Prevention Director Dr. Rochelle Walensky said at a news briefing Monday. (Kristin Murphy, Deseret News)

Estimated read time: 4-5 minutes

WASHINGTON — This year’s flu shot appears to be “a very good match” to the circulating strains, U.S. Centers for Disease Control and Prevention Director Dr. Rochelle Walensky said at a news briefing Monday. However, she noted that flu vaccinations are lagging behind the pace of previous years.

Through the end of October, CDC data shows that vaccinations for pregnant women, a group that is more vulnerable to severe illness from influenza, are down about 12% from the same point in 2021.

Vaccination rates for seniors, the age group most likely to be hospitalized with influenza, were down about three percentage points from October 2021.

Flu vaccinations for children are down about 5% compared with where they were before the COVID-19 pandemic, Walensky said.

In a typical year, about 60% of American adults get vaccinated against influenza.

Flu hits the US hard

Flu season has gotten off to an early and severe start in the U.S., with hospitalization rates hitting levels that typically aren’t seen until December or January.

“We, of course, look in real time as to how well we think the influenza match is to what is circulating right now. The good news is that looks like it is a very good match,” Walensky said of the early start to the respiratory virus season.

She noted that the CDC would have more definitive data later in the season but that the data is encouraging.

Walensky said that even when the vaccine doesn’t closely match the circulating flu strains, “We see a 35% decrease in rates of hospitalization … which really just emphasizes, when we do have a good match, how much more effective it will be.”

CDC data shows that nearly 20,000 people in the United States were admitted to the hospital for flu during the week of Thanksgiving, almost double the number of admissions from the week before.

COVID-19 hospitalizations have ticked up as well, rising 27% in the week after Thanksgiving. But COVID-19 is no longer the only virus straining hospitals.

Just 5% of the U.S. population lives in an area considered to have a high COVID-19 community level.

Walensky said Monday that the CDC was “actively looking into” expanding its community levels beyond COVID-19 to include the effects of other viruses, such as the flu.

“In the meantime, what I do want to say is, one need not take wait for CDC action in order to put a mask,” she said.

People who are sick should stay home and away from others, use good hygiene like covering coughs and washing hands frequently, use a high-quality mask and improve the ventilation in indoor spaces, Walensky said.

Treatment is available

If you do get sick, it’s important to get tested, even if you’ve been vaccinated, said Dr. Sandra Fryhofer, board chair of the American Medical Association and an internal medicine physician in Atlanta.

If you have COVID-19 or the flu, there are antiviral medications for both. But flu antivirals don’t work against COVID-19, and vice versa.

“It is going to be a confusing respiratory infections season. Figuring out what’s making people sick is going to be a conundrum,” Fryhofer said.

In response to a question about shortages of key medications during this rough virus season, Walensky said that “CDC is aware of the reports of some of the shortages for both antivirals as well as antibiotics across the country. I know FDA is working … with manufacturers to try and explore what can be done to address this.”

She also urged doctors not to prescribe antibiotics for illnesses caused by viruses.

Dr. William Schaffner, an infectious disease expert at Vanderbilt University Medical Center in Nashville, said he and his colleagues have been astonished by the steep increase in flu cases this season. They have also wondered what could be causing it.

He says it’s likely that after two years without much flu activity in the U.S., we lost some of our immunity against that virus just as the country has returned to more normal travel and activity patterns.


It is going to be a confusing respiratory infections season. Figuring out what’s making people sick is going to be a conundrum.

–Sandra Fryhofer, American Medical Association


“Some of it has got to do with our behaviors in the past, having avoided flu and now opening up our lives to activities such as travel, religious services, getting together with families, going out to entertainment venues and doing all those things that take us into groups,” he said.

The flu vaccines are good at preventing severe outcomes, he said, but they don’t do much to stop the virus’ spread.

“It keeps you out of the emergency room, the hospital, the intensive care unit and the cemetery. It’s not very good at interrupting transmission, and it is not very good at preventing milder infection,” he said.

Schaffner says it’s likely that flu hospitalizations are going up because the virus is hitting the elderly, who, on the whole, tend to get less protection from vaccinations.

“The vaccine works least well among the population we most want to protect, namely older people, and that’s because they have immune systems that are much less robust than the immune systems of younger people.”

Schaffner noted that there are high-dose vaccines for seniors, which are preferred for this age group to help increase their protection.

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Flu vaccine appears to be a very good match to circulating strains, CDC says



CNN
 — 

This year’s flu shot appears to be “a very good match” to the circulating strains, US Centers for Disease Control and Prevention Director Dr. Rochelle Walensky said at a news briefing Monday. However, she noted that flu vaccinations are lagging behind the pace of previous years.

Through the end of October, CDC data shows that vaccinations for pregnant women, a group that is more vulnerable to severe illness from influenza, are down about 12% from the same point in 2021.

Vaccination rates for seniors, the age group most likely to be hospitalized with influenza, were down about 3 percentage points from October 2021.

Flu vaccinations for children are down about 5% compared with where they were before the Covid-19 pandemic, Walensky said.

In a typical year, about 60% of American adults get vaccinated against influenza.

Flu season has gotten off to an early and severe start in the US, with hospitalization rates hitting levels that typically aren’t seen until December or January.

“We, of course, look in real time as to how well we think the influenza match is to what is circulating right now. The good news is that looks like it is a very good match,” Walensky said of the early start to the respiratory virus season.

She noted that the CDC would have more definitive data later in the season but that the data is encouraging.

Walensky said that even when the vaccine doesn’t closely match the circulating flu strains, “We see a 35% decrease in rates of hospitalization … which really just emphasizes, when we do have a good match, how much more effective it will be.”

CDC data shows that nearly 20,000 people in the United States were admitted to the hospital for flu during the week of Thanksgiving, almost double the number of admissions from the week before.

Covid-19 hospitalizations have ticked up as well, rising 27% in the week after Thanksgiving. But Covid-19 is no longer the only virus straining hospitals.

Just 5% of the US population lives in an area considered to have a high Covid-19 community level.

Walensky said Monday that the CDC was “actively looking into” expanding its community levels beyond Covid-19 to include the effects of other viruses, such as the flu.

“In the meantime, what I do want to say is, one need not take wait for CDC action in order to put a mask,” she said.

People who are sick should stay home and away from others, use good hygiene like covering coughs and washing hands frequently, use a high-quality mask and improve the ventilation in indoor spaces, Walensky said.

If you do get sick, it’s important to get tested, even if you’ve been vaccinated, said Dr. Sandra Fryhofer, board chair of the American Medical Association and an internal medicine physician in Atlanta.

If you have Covid-19 or the flu, there are antiviral medications for both. But flu antivirals don’t work against Covid-19, and vice versa.

“It is going to be a confusing respiratory infections season. Figuring out what’s making people sick is going to be a conundrum,” Fryhofer said.

In response to a question about shortages of key medications during this rough virus season, Walensky said that “CDC is aware of the reports of some of the shortages for both antivirals as well as antibiotics across the country. I know FDA is working…with manufacturers to try and explore what can be done to address this.”

She also urged doctors not to prescribe antibiotics for illnesses caused by viruses.

Dr. William Schaffner, an infectious disease expert at Vanderbilt University Medical Center in Nashville, said he and his colleagues have been astonished by the steep increase in flu cases this season. They have also wondered what could be causing it.

He says it’s likely that after two years without much flu activity in the US, we lost some of our immunity against that virus just as the country has returned to more normal travel and activity patterns.

“Some of it has got to do with our behaviors in the past, having avoided flu and now opening up our lives to activities such as travel, religious services, getting together with families, going out to entertainment venues and doing all those things that take us into groups,” he said.

The flu vaccines are good at preventing severe outcomes, he said, but they don’t do much to stop the virus’ spread.

“It keeps you out of the emergency room, the hospital, the intensive care unit and the cemetery. It’s not very good at interrupting transmission, and it is not very good at preventing milder infection,” he said.

Schaffner says it’s likely that flu hospitalizations are going up because the virus is hitting the elderly, who, on the whole, tend to get less protection from vaccinations.

“The vaccine works least well among the population we most want to protect, namely older people, and that’s because they have immune systems that are much less robust than the immune systems of younger people.”

Schaffner noted that there are high-dose vaccines for seniors, which are preferred for this age group to help increase their protection.

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New Banana-Derived Therapy Is Effective Against All Known Coronaviruses and Flu Strains

According to the researchers, the therapy, H84T-BanLec, holds unique promise. They hope to start human testing soon. 

The potential therapy was derived from a banana protein.

A study published on January 13th, 2020 touted the development of a potential therapy that may be used to fight all known strains of the flu.

One week later, the first laboratory-confirmed case of

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Flu variant that hits kids and seniors harder than other strains is dominant in U.S. right now

A sign advertising flu shots is displayed at a Walgreens pharmacy on January 22, 2018 in San Francisco, California. A strong strain of H3N2 influenza has claimed the lives of 74 Californians under the age of 65 since the flu season began in October of last year.

Justin Sullivan | Getty Images

A variant of the flu that hits kids and seniors worse than other strains of the virus is dominant in the U.S. right now, setting the country up for a potentially bad flu season.

Public health labs have detected influenza A(H3N2) in 76% of the more than 3,500 respiratory samples that have tested positive for the flu and were analyzed for the virus subtype, according to a surveillance report published Friday by the Centers for Disease Control and Prevention.

The H3N2 variant has been associated with more severe flu seasons for children and the elderly in the past, according to Dr. Jose Romero, director the CDC’s National Center for Immunization and Respiratory Disease.

“There are also early signs of influenza causing severe illness in precisely these two groups of individuals this season,” Romero told reporters on a call earlier this month.

The flu hospitalization rate has surged to a decade high this season. Overall, about 8 people per 100,000 are being hospitalized with the flu right now but seniors and the youngest children are much harder hit than other age groups, according to CDC data.

The hospitalization rate for seniors is more than double the general population at 18 per 100,000. For kids younger than age five, the hospitalization rate is about 13 per 100,000.

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At least 4.4 million people have fallen ill with the flu, 38,000 have been hospitalized, and 2,100 have died since the season started. Seven kids have died from the flu so far this season.

“When we have more H3N2, we usually have a more severe flu season — so longer duration, more children affected, more children with severe disease,” said Dr. Andi Shane, a pediatrician and infectious disease expert at Children’s Healthcare Atlanta.

The other influenza A variant, H1N1, is generally associated with less severe seasons compared with H3N2, Shane said. H1N1 makes up about 22% of sample that have tested positive for flu and were analyzed for a subtype, according to CDC.

The percentage of patients reporting symptoms similar to the flu, a fever of 100 degrees or greater plus a sore throat or cough, is the highest in Virginia, Tennessee, South Carolina, Alabama and Washington D.C right now, according to CDC.

Respiratory illnesses are also very high in Arkansas, Colorado, Georgia, Kentucky, New Jersey, Maryland, Mississippi, New Mexico, North Carolina and Texas, according to CDC.

The CDC recommends that everyone 6 months or older get a flu shot. Children younger than age 8 who are receiving the vaccine for the first time should get two doses for the best protection.

The flu vaccine is normally 40% to 60% effective at preventing illness, but people who do still get sick are less likely to end up in the hospital or die, according to the CDC.

Public health officials are also encouraging people to stay home when they are sick, cover coughs and sneezes and wash hands frequently. Those who want to take extra precautions can consider wearing a facemask indoors in public.

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Europe’s debt market strains force some governments to rework trading rules

Oct 31 (Reuters) – Some euro zone countries have eased rules for the banks that manage the trading of their government debt to help them cope with some of the most challenging market conditions in years, officials told Reuters.

Out of 11 major euro area debt agencies Reuters contacted, officials in the Netherlands and Belgium told Reuters they have loosened various market-making obligations dictating how actively these banks should trade their debt.

France, Spain and Finland said their rules are already structured to automatically take account of market tensions. Germany and Austria said they do not set such rules.

As the European Central Bank unwinds years of buying the region’s debt, while the war in Ukraine, an energy shock and turmoil in Britain are making investors wary of loading up on government bonds, debt managers are adjusting to a less liquid, more volatile market.

That in turn, could raise borrowing costs for governments, already squeezed by climbing interest rates and energy-related spending, and bring more uncertainty for institutions, such as pension funds, which seek in government debt safety and stability.

Euro zone government debt bid-ask spreads, the difference between what buyers are offering and sellers are willing to accept and a measure of how smooth the trading is, have risen up to four-fold since the summer of 2021, data compiled by MarketAxess (MKTX.O) for Reuters showed. The data tracked German, Italian, French, Spanish and Dutch bonds, markets which account for the vast majority of euro zone debt with nearly 8 trillion euros outstanding.

Bond bid-ask spreads soar

LOOSENED OBLIGATIONS

Wider spreads mean more volatility and higher transaction costs. So governments expect, and some formally require their primary dealers – banks that buy government debt at auctions and then sell to investors and manage its trading – to keep those tight.

In markets with formal requirements, they also face other “quoting obligations” to ensure the best possible liquidity. Those obligations have been loosened in some countries to account for heightened market stress.

Jaap Teerhuis, head of dealing room at the Dutch State Treasury, said several of its quoting obligations, including bid-ask spreads, had been loosened.

“Volatility is still significantly higher compared to before the (Ukraine) war and also ECB uncertainty has also led to more volatility and more volatility makes it harder for primary dealers to comply,” he said.

Liquidity has been declining since late 2021 as traders started anticipating ECB rate hikes, Teerhuis said. The Netherlands then loosened its quoting obligations following the invasion of Ukraine.

Belgium’s quoting obligations also move with changes in trading conditions. But it has relaxed since March the rules on how many times per month dealers are allowed to fail to comply with them and has also reduced how much dealers are required to quote on trading platforms, its debt agency chief Maric Post said.

The two countries also loosened rules during the COVID-19 pandemic. Belgium’s Post said that lasted only four months in 2020, but it has kept obligations looser for much longer this time.

Finland said it has not changed its rules, but could not rule out acting if conditions persist or worsen.

Outside the bloc, Norway has also allowed dealers to set wider bid-ask spreads.

In Italy, debt management chief Davide Iacovoni said on Tuesday it was considering adjusting the way it ranks primary dealers each year to encourage them to quote tight spreads. Such rankings can affect which banks get to take part in lucrative syndicated debt sales.

Debt offices where obligations adapt automatically said attempts to enforce pre-determined bid-ask spreads in volatile markets would discourage primary dealers from providing liquidity and cause more volatility.

“If the market is too volatile, if it’s too risky, if it’s too costly, it’s better to adjust the bid-offer to what is the reality of the market than to force liquidity,” France’s debt chief Cyril Rousseau told an event on Tuesday.

Britain’s September sell-off highlighted how liquidity can evaporate fast in markets that are already volatile when a shock hits. In that case, the government’s big spending plans triggered large moves in debt prices, forcing pension funds to resort to fire sales of assets to meet collateral calls.

‘FRAGMENTED MARKET’

Allianz senior economist Patrick Krizan said with bond volatility nearing 2008 levels, a fragmented market for safe assets was a concern.

The euro zone is roughly 60% the size of the U.S. economy but it relies on Germany’s 1.6 trillion euro bond market as a safe haven – a fraction of the $23-trillion U.S. Treasury market.

In the case of a volatility shock “you can very easily fall into a situation where some markets are really drying up,” Krizan said. “For us it’s one of the biggest risks for the euro area.”

For example, the Netherlands like Germany has a top, triple A rating. But like other smaller euro zone markets it does not offer futures, a key hedging instrument, and so far this year the premium it pays over German debt has doubled to around 30 basis points.

Smaller governments pay premium over bigger rating peers

Efforts by debt officials are welcomed by European primary dealers, whose numbers have dwindled in recent years because of shrinking profit margins and tougher regulation.

Two officials at primary dealer banks said that fulfilling the quoting obligations in current conditions would force them to take on more risk.

“If (issuers) want private sector market-making, it needs to be profitable, or why would anyone do it? And it can’t be if rates move around 10-15 basis points a day,” one said of moves of a scale that had rarely been seen in these markets in recent years.

($1 = 0.9970 euros)

Reporting by Yoruk Bahceli and Dhara Ranasinghe; additional reporting by Belen Carreno in MADRID, Lefteris Papadimas in ATHENS and Padraic Halpin in DUBLIN; editing by Tomasz Janowski

Our Standards: The Thomson Reuters Trust Principles.

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Two antibodies identified in Israel can fight all known COVID strains, study finds

Israeli scientists say they have identified antibodies that are so powerful in neutralizing the coronavirus that they could eliminate the need for more vaccine boosters.

A research team at Tel Aviv University experimented with numerous antibodies and found that two in particular neutralize all known strains of the coronavirus, including Delta and Omicron, in a lab setting.

Antibody infusions are already used to treat some coronavirus patients, and microbiologist Dr. Natalia Freund, who directed the new study, said the antibodies she identified could be used to concoct a particularly potent infusion.

Based on their performance in lab conditions, the antibodies could provide the extra protection that today comes from booster shots, she said, adding that this could potentially make extra shots unnecessary among vaccinated people.

“COVID-19 infection can cause serious illness, and we know that providing antibodies in the first days following infection can stop the spread of the virus,” Freund said.

“It is therefore possible that by using effective antibody treatment, we will not have to provide booster doses to the entire population every time there is a new variant,” she added.

According to Freund, on a technical level, the reason for the success of the two antibodies seems to be that they bind to a different part of the coronavirus spike protein than most others.

Illustrative image: a coronavirus ward at the Barzilai Medical Center, in Ashkelon, Israel, Thursday, Aug. 26, 2021. (AP Photo/Maya Alleruzzo)

Freund’s latest research, newly peer-reviewed and published in Communications Biology, comes from investigations that began in her lab in October 2020.

Working with doctoral students Michael Mor and Ruofan Lee, she sequenced all the B immune system cells from the blood of people who had recovered from the original COVID strain in Israel, and isolated nine antibodies that the patients produced.

Now, the top two antibodies have been tested against a range of variants, and performed well against all of them.

“According to our findings, the effectiveness of the first antibody, TAU-1109, in neutralizing the Omicron strain is 92 percent, and in neutralizing the Delta strain, 90%,” Freund said.

“The second antibody, TAU-2310, neutralizes the Omicron variant with an efficacy of 84%, and the Delta variant with an efficacy of 97%,” she added.

The antibodies are named TAU because they were identified at Tel Aviv University.

To ensure that her lab work was done correctly, Freund sent the antibodies to have their effectiveness against live viruses checked in laboratory cultures at the University of California San Diego, and for further testing at Bar-Ilan University’s medicine faculty in the Galilee. These studies corroborated her findings.

Natalia Freund of Tel Aviv University (courtesy of Tel Aviv University)

Freund said that antibodies clearly give strong protection, as they prevent infection straight after recovery — but then they wane, and immunity reduces. In her view, this makes it logical to invest in artificially boosting antibodies, and she hopes to do exactly this with the antibodies she identified.

“For reasons we still don’t yet fully understand, the level of antibodies against COVID-19 declines significantly after three months,” she explained. “This is why we see people getting infected again and again, even after being vaccinated three times.

“COVID-19 infection can cause serious illness, and we know that providing antibodies in the first days following infection can stop the spread of the virus. It is therefore possible that by using effective antibody treatment, we will not have to provide booster doses to the entire population every time there is a new variant.”

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Omicron BA.5 & BA.4 Officially Dominant Covid Strains In U.S. – Deadline

A little over a month after the more transmissible BA.2.12.1 Omicron subvariant became officially dominant in the U.S. on May 24, two sister subvariants of Omicron have quickly eclipsed BA.2.12.1 across the country.

BA.5 and BA.4 are, like BA.2.12.1, more transmissible, but have the added advantage of reportedly being more able to reinfect those who’ve already had Covid.

“We now report findings from a systematic antigenic analysis of these surging Omicron subvariants,” says a paper published last month to the BioRxiv preprint server. “BA.2.12.1 is only modestly (1.8-fold) more resistant to sera from vaccinated and boosted individuals than BA.2. On the other hand, BA.4/5 is substantially (4.2-fold) more resistant and thus more likely to lead to vaccine breakthrough infections.”


CDC

While BA.2.12.1 accounts for 42% of new cases this week, Centers for Disease Control and Prevention data shows that’s down from about 53% the week before. BA.5 and BA.4 by contrast have grown their shares from 25% and 12%, respectively, last week to about 37% and 16% this week. That means together the two variants which first emerged in South Africa earlier this year have jumped to a 55% share of all new cases in the last week.



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