Tag Archives: Strain

Israeli who recovered from COVID-19 reinfected with South African strain

For the first time, an Israeli man who previously recovered from the coronavirus was found Sunday to be reinfected with the so-called South African strain, Hebrew media reported.

The diagnosis came amid continued uncertainty on the effectiveness of the Pfizer/BioNTech vaccine that Israel is using for its mass inoculation program against the new strains of the virus.

Ziv Yaffe, 57, from the central region of the country, recently returned from Turkey. Speaking to Channel 12 news, he said that whereas during his first infection in August he had “all the symptoms,” the second time around he felt fine.

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Yaffe returned to Israel on January 16. By January 23, he had a bit of a runny nose and decided to get a virus test, as he was participating in follow-up research at the Assaf Harofeh Medical Center. The test showed that he was reinfected and further testing revealed that he had caught the South African mutation.

Shai Efrati, head of research and development at the medical center, told the station that Yaffe’s case was unique because doctors had a complete medical record of his bouts with the virus.

“It is the first time that we have a full record, of infection, recovery, reinfection, and that the antibodies that he had protected him from the mutation,” Efrati said.

“What we learn is that when there are antibodies, they protect against illness,” he said.

Screen capture from video of Ziv Yaffe, left, who was reinfected with the coronavirus, and Shai Efrati of the Assaf Harofeh Medical Center. (Channel 12 news)

Efrati cautioned that it was too early to conclude that anyone who has had the disease is also protected against other mutations, saying it would require more similar cases before such conclusions could be drawn.

But, he added, Yaffe’s case is “very encouraging.”

Yaffe said that in addition to not feeling unwell, family members and others had been in close contact with him during the period of his second infection, yet none caught the virus from him.

His case is the second time the South African variant has been brought into Israel from Turkey, according to the Ynet website.

Health officials are concerned that the South African mutation, similar to the British and Californian strains which are considered more infectious, could lead to another wave of the virus among those who have recovered from previous infection and are not being vaccinated as part of the immunization drive.

All previous patients with the South African mutation, first discovered in South Africa in December, were people who came back to the country from South Africa, Ethiopia, or Dubai, according to the report.

Sharon Alroy-Preis, the acting head of the ministry’s public health division, speaks virtually to the Knesset’s Constitution, Law, and Justice Committee on January 6, 2021. (Screen capture: YouTube)

On Saturday, Dr. Sharon Alroy-Preis, the head of public health services at the Health Ministry, told the Kan public broadcaster there were preliminary indications the coronavirus vaccines may prove less effective in shielding against the South African variant.

“We don’t have evidence yet that any of the variants are completely resistant to the vaccine, but there is some preliminary evidence to say that perhaps the effectiveness of the vaccine is somewhat less against the South African variant,” Alroy-Preis said.

She said testing was still in progress to clarify the matter.

Pfizer and BioNTech, whose vaccine is being used in Israel’s world-leading vaccine drive, said Thursday that early tests suggest their immunization would be protective against the variants from South Africa and Britain.

Their study found that the antibodies were able to neutralize all the sets of mutations tested. It noted that the effect was “slightly lower” against three mutations in the variant found in South Africa, including E484K. But the firms said that it was “unlikely to lead to a significant reduction in the effectiveness of the vaccine.”

The Health Ministry last week confirmed that three more cases of the South African coronavirus variant have been found in Israel, bringing the total number of infections from the strain to 30. Three of the cases were discovered in a random sampling, raising concerns of undetected community spread.

Meanwhile, the British variant is spreading wildly in Israel, with health officials blaming the continued high coronavirus caseload after weeks of lockdown on the UK mutation. The daily infections continue to remain in the thousands, despite Israel’s strict restrictions and vaccination campaign.

A man receives a COVID-19 vaccine injection at a vaccination center in Jerusalem, on January 28, 2021. (Olivier Fitoussi/Flash90)

Over 3 million Israelis — almost one-third of its population — have received the first dose of the vaccine, and 1.7 million have received both shots. The shots are being administered according to a plan that began with medical workers, those over the age of 60 and at-risk groups, with the age limit dropping steadily as more citizens complete the two-shot vaccination cycle.

In an effort to keep the virus variants out of the country, Israel has closed its main international airport, including to its own citizens. The order is set to expire Sunday, but will likely be extended.

The government on Sunday is expected to extend the nationwide lockdown by another week to drive down infection rates.

Since the start of the virus outbreak early last year 641,373 people in Israel have been diagnosed with the virus, according to Health Ministry figures released Sunday. The death toll stood at 4,768.

Agencies contributed to this report.

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California may have highly contagious homegrown COVID-19 strain

Scientists in California believe there is a homegrown coronavirus strain in the state that could be responsible for the dramatic rise in cases, a report said on Sunday.

Two separate research groups have discovered the apparent California strain while looking for the new variant that is believed to have come from the United Kingdom, according to the Los Angeles Times.

The supposed California strain is in the same “family tree” as the U.K. strain and could be behind the state’s spread over the past few months, the paper said.

One of the labs that discovered the strain, Cedars-Sinai Medical Center in Los Angeles said that it amounted to 24 percent of about 4,500 viral samples gathered throughout California in the last weeks of 2020.

Another analysis found that 25 percent of 332 samples taken in Northern California were of the new strain.

“There was a homegrown variant under our noses,” Dr. Charles Chiu, a laboratory medicine specialist at University of California, San Francisco, told the newspaper.

Chiu said that they only found the strain when searching for the UK variant.

Dr. Eric Vail, a pathologist at Cedars Sinai, said the strain could be responsible for doubling the state’s total death toll in the space of less than three months.

“It probably helped to accelerate the number of cases around the holiday season,” Vail said.

“But human behavior is the predominant factor in the spread of a virus, and the fact that it happened when the weather became colder and in the midst of the holidays when people gather is not an accident.”

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Coronavirus live news: US nears 25m cases as three infections linked to Australian Open confirmed as UK strain | World news













21:17

In December, the UK reported a Covid-19 variant of concern, commonly referred to as the B117 variant, which appeared to be more transmissible. Since then, scientists have established that B117 is somewhere between 50% to 70% more transmissible than other variants. If more people are getting sick, there is more pressure on health systems, and in the UK health services are so overloaded a country-wide lockdown has been enforced.

While many scientists say B117 does not appear more deadly, researchers on the UK government’s New and Emerging Respiratory Virus Threats Advisory Group found it may increase the death rate by 30% to 40%, though their sample size was small and they said more research is needed. With B117 now detected in more than 50 countries, understanding the variant is urgent.

But other variants of concern have also been identified, including in California, South Africa and Brazil.

So exactly what is a variant, and how many are there? And why are some variants of more concern than others?

Answers at the link below:













20:56

And what a year it has been. In just over a month’s time, I will have been liveblogging international developments in the coronavirus pandemic for eight hours a day, every day on the global blog – which has been running non-stop around the world almost uninterrupted for more than a year.

This time last year, I was living in Beirut, having just returned from reporting on the bushfires in Australia.

Where were you at the end of January 2020? Let me know on Twitter @helenrsullivan.

Updated













20:53

Monday marks one year since first cases in Australian state of New South Wales













20:50

Summary













20:38

Possible community case in New Zealand

An update on New Zealand now, where a possible community case of Covid is being reported in the northernmost province of Northland.

The “probable” case is in the community, a ministry of health spokesperson said, rather than a managed isolation facility.

The director-general of health Dr Ashley Bloomfield, and the minister of covid-19 response, Chris Hipkins, will hold a media stand-up at 4pm to share the latest information.

The last case of covid-19 in the community was recorded in Auckland on November 18 and contained within a matter of days after central Auckland was shut down.

Overall less than 2000 people contracted coronavirus in 2020, and 26 people died. New Zealand is pursuing an elimination strategy towards the disease.













20:27













20:07

Mainland China reports 80 new cases vs 107 a day earlier













19:58

No new local cases in Australian state of Victoria

Updated













19:56

UK to quarantine arrivals from high-risk countries – reports













19:54

Three infections linked to Australian Open confirmed as UK strain













19:48

A possible outbreak of Covid-19 is being reported in New Zealand, in the northernmost province of Northland.

The probable case has emerged in the community, but is NOT a probable case of community transmission, according to the New Zealand Department of Health.

The outbreak – if confirmed – is said to be related to a person recently released from a managed isolation facility, the New Zealand Herald reports.

The director-general of health Dr Ashley Bloomfield, and the minister of covid-19 response, Chris Hipkins, will hold a media stand-up at 4pm to share the latest information.

Updated













19:46

Australian state of New South Wales confirms zero local cases

New South Wales has recorded no new locally acquired cases of Covid-19 on Sunday and three in hotel quarantine. It brings the number of new cases listed in Australia today to four, all in hotel quarantine, after Victoria reported one new case in Melbourne’s quarantine hotels. Queensland has recorded no new cases on Sunday.

Health officials in NSW have urged people to get a Covid-19 test if they have any cold or flu symptoms, however mild, after just 11,344 tests were conducted in the 24-hours to 8pm last night – well below the daily target of 30,000 tests.




Arriving passengers at Sydney’s Kingsford Smith International airport are sent onto buses for mandatory 14 day quarantine on January 22, 2021 in Sydney, Australia. Photograph: James D Morgan/Getty Images

Authorities say they have also detected fragments of the virus in sewage tests at the Warriewood and North Head treatment plants,. The former covers about 70,000 people in the Northern Beaches area, and the latter has a catchment of 1.3 million people from a large chunk of Sydney extending north of the Parramatta River from Western Sydney to Manley.

NSW Health said the detection “likely reflects known recent confirmed cases in those areas,” but urged anyone living in those areas to get tested if they had any symptoms.













19:43

Updated



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Studies of South African Coronavirus Strain Raise Concerns About Immune Response

JOHANNESBURG—Three new laboratory studies are raising concerns that the immune response triggered by a Covid-19 infection or vaccination may be less effective at protecting against the new strain of the coronavirus that first emerged in South Africa.

The findings come from experiments done in the laboratory and only look at certain elements of a body’s immune response. Still, they reinforce the possibility that vaccine makers and regulators will need to update Covid-19 vaccines as the virus evolves.

A fourth study, conducted by scientists at BioNTech SE and Pfizer Inc. and published by the companies, showed that their vaccine successfully neutralized a variant that was initially detected in the U.K. That study didn’t include the South African strain.

The U.K. variant has already spread to many other countries, including the U.S.

More than a year into the pandemic, the discovery of new variants that appear to have made the virus more contagious is forcing researchers to adapt their understanding of the coronavirus that causes Covid-19. One concern, researchers said, is that the new strains are emerging in countries where a significant percentage of people have already built up an immune response to earlier variants after getting Covid-19.

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