- Ukraine pulls down Soviet hammer and sickle from towering 335ft ‘Motherland’ statue in heart of Kyiv commemora Daily Mail
- Soviet emblem cut off Ukraine’s Motherland Monument statue in Kyiv | WION Originals WION
- Kyiv’s Motherland monument gets a makeover — but at what cost? POLITICO Europe
- Soviet symbol removed from Kyiv landmark in latest step in ’de-russification’ • FRANCE 24 FRANCE 24 English
- Kyiv’s iconic Motherland monument to bear Tryzub instead of Hammer and Sickle Yahoo News
- View Full Coverage on Google News
Tag Archives: Sickle
Sanofi taps Scribe for in vivo partnership worth more than $1.2B biobucks aimed at sickle cell and beyond – FierceBiotech
- Sanofi taps Scribe for in vivo partnership worth more than $1.2B biobucks aimed at sickle cell and beyond FierceBiotech
- Sanofi licenses CRISPR enzyme in bid to develop safer, simpler sickle cell cure STAT
- Mirum Pharmaceuticals buys Travere Therapeutics portfolio of bile acid drugs for up to $445M – San Francisco Business Times The Business Journals
- Sanofi goes back to Scribe Evaluate Pharma
- East Bay’s Scribe Therapeutics lands 2nd big deal with Sanofi, this one aimed initially at sickle cell disease – San Francisco Business Times The Business Journals
- View Full Coverage on Google News
As Novo Nordisk begins PhII sickle cell trial, it snags a later-stage blood disorder drug in $1.1B Forma buy – Endpoints News
Lumakras, Amgen’s groundbreaking KRAS drug, was approved on data from an open-label, single-arm study suggesting, among other things, median progression-free survival of 6.8 months for patients with KRASG12C-mutated non-small cell lung cancer.
Now, Amgen says it has the first proof that Lumakras beats chemotherapy — the current standard of care — on that metric.
Further analyses are still ongoing and data will be reserved for future medical conferences, Amgen said, remaining tight-lipped. What it will say is that the drug, formerly known as sotorasib, met the primary endpoint of PFS in the CodeBreaK 200 trial, where it went head to head with intravenous docetaxel. Among 345 patients, Lumakras demonstrated “statistical significance and superiority” over the chemo.
Keep reading Endpoints with a free subscription
Unlock this story instantly and join 149,300+ biopharma pros reading Endpoints daily — and it’s free.
Brother in Maharashtra Honor Killing Beheads Pregnant Sister With a Sickle While Mother Holds Her Down
A pregnant 19-year-old woman in India was allegedly decapitated with a sickle by her younger brother, who then posed for a selfie with her severed head along with their mother.
The horrific murder—deemed an honor killing after the woman eloped with her fiance without her family’s consent—took place in the western Indian state of Maharashtra on Sunday, according to the BBC. Both the young man, identified as Sanket Mote, and the pair’s mother, identified as Shobhabai Mote, have been arrested in connection with the murder of the woman, named Kirti Avinash Thore.
“Kirti was preparing tea when Sanket attacked her from behind with a sickle while the mother caught her daughter’s legs,” Kailash Prajapati, Assistant Police Commissioner, SDPO Vaijapur told local media. “He beheaded her and brought the head outside the house. We suspect that the mother and son took a selfie with her head. We have sent the phone to the forensic lab to try and retrieve the photo. The duo then left on the bike.”
Local media reports suggest that the woman’s mother and brother came to visit the couple ostensibly to reconcile, but when her newlywed husband left the room to give them privacy, the pair allegedly killed her. The husband reportedly fled the house out of fear he might also be killed.
It is unclear if the sickle was in the house or if the mother and son had concealed it with intent to use it.
Indian news agency ANI says the 38-year-old mother and her 18-year-old son dragged the victim’s head out of the house and put it on display in front of neighbors, apparently admitting to the crime.
The man told police that his sister failed to secure consent before marrying her boyfriend last June. She had become estranged from her family since the elopement but her mother visited her a week before she was killed, at which time she learned her daughter was pregnant.
She and her son returned a week later and allegedly carried out the horrific murder.