Tag Archives: Prevents

Better Ventilation Prevents COVID Spread. Are Companies Aware?

Americans are abandoning their masks. They’re done with physical distancing. And, let’s face it, some people are just never going to get vaccinated.

Yet a lot can still be done to prevent covid infections and curb the pandemic.

A growing coalition of epidemiologists and aerosol scientists say that improved ventilation could be a powerful tool against the coronavirus — if businesses are willing to invest the money.

“The science is airtight,” said Joseph Allen, director of the Healthy Buildings programat Harvard University’s T.H. Chan School of Public Health. “The evidence is overwhelming.”

Although scientists have known for years that good ventilation can reduce the spread of respiratory diseases such as influenza and measles, the notion of improved ventilation as a front-line weapon in stemming the spread of covid-19 received little attention until March. That’s when the White House launched a voluntary initiativeencouraging schools and work sites to assess and improve their ventilation.

The federal American Rescue Plan Act provides $122 billion for ventilation inspections and upgrades in schools, as well as $350 billion to state and local governments for a range of community-level pandemic recovery efforts, including ventilation and filtration. The White House is also encouraging private employers to voluntarily improve their indoor air quality and has provided guidelines on best practices.

The White House initiative comes as many employees are returning to the office after two years of remote work and while the highly contagious BA.2 omicron subvariant gains ground. If broadly embraced, experts say, the attention to indoor air quality will provide gains against covid and beyond, quelling the spread of other diseases and cutting incidents of asthma and allergy attacks.

The pandemic has revealed the dangerous consequences of poor ventilation, as well as the potential for improvement. Dutch researchers, for example, linked a 2020 covid outbreak at a nursing home to inadequate ventilation. A choir rehearsal in Skagit Valley, Washington, early in the pandemic became a superspreader event after a sick person infected 52 of the 60 other singers.

Ventilation upgrades have been associated with lower infection rates in Georgia elementary schools, among other sites. A simulation by the Centers for Disease Control and Prevention found that combining mask-wearing and the use of portable air cleaners with high-efficiency particulate air filters, or HEPA filters, could reduce coronavirus transmission by 90%.

Scientists stress that ventilation should be viewed as one strategy in a three-pronged assault on covid, along with vaccination, which provides the best protection against infection, and high-quality, well-fitted masks, which can reduce a person’s exposure to viral particles by 95%. Improved airflow provides an additional layer of protection — and can be a vital tool for people who have not been fully vaccinated, people with weakened immune systems, and children too young to be immunized.

One of the most effective ways to curb disease transmission indoors is to swap out most of the air in a room — replacing the stale, potentially germy air with fresh air from outside or running it through high-efficiency filters — as often as possible. Without that exchange, “if you have someone in the room who’s sick, the viral particles are going to build up,” said Linsey Marr, a professor of civil and environmental engineering at Virginia Tech.

Exchanging the air five times an hour cuts the risk of coronavirus transmission in half, according to research cited by the White House Office of Science and Technology Policy. Yet most buildings today exchange the air only once or twice an hour.

That’s partly because industry ventilation standards, written by a professional group called the American Society of Heating, Refrigerating and Air-Conditioning Engineers, or ASHRAE, are voluntary. Ventilation standards have generally been written to limit odors and dust, not control viruses, though the society in 2020 released new ventilation guidelines for reducing exposure to the coronavirus.

But that doesn’t mean building managers will adopt them. ASHRAE has no power to enforce its standards. And although many cities and states incorporate them into local building codes for new construction, older structures are usually not held to the same standards.

Federal agencies have little authority over indoor ventilation. The Environmental Protection Agency regulates standards for outdoor air quality, while the Occupational Safety and Health Administration enforces indoor-air-quality requirements only in health care facilities.

David Michaels, an epidemiologist and a professor at the George Washington University Milken Institute School of Public Health, said that he’d like to see a strong federal standard for indoor air quality but that such calls inevitably raise objections from the business community.

Two years into the pandemic, it’s unclear how many office buildings, warehouses, and other places of work have been retooled to meet ASHRAE’s recommended upgrades. No official body has conducted a national survey. But as facilities managers grapple with ways to bring employees back safely, advocates say ventilation is increasingly part of the conversation.

“In the first year of the pandemic, it felt like we were the only ones talking about ventilation, and it was falling on deaf ears,” said Allen, with Harvard’s Healthy Buildings program. “But there are definitely, without a doubt, many companies that have taken airborne spread seriously. It’s no longer just a handful of people.”

A group of Head Start centers in Vancouver, Washington, offers an example of the kinds of upgrades that can have impact. Ventilation systems now pump only outdoor air into buildings, rather than mixing fresh and recirculated air together, said R. Brent Ward, the facilities and maintenance operations manager for 33 of the federally funded early childhood education programs. Ward said the upgrades cost $30,000, which he funded using the centers’ regular federal Head Start operating grant.

Circulating fresh air helps flush viruses out of vents so they don’t build up indoors. But there’s a downside: higher cost and energy use, which increases the greenhouse gases fueling climate change. “You spend more because your heat is coming on more often in order to warm up the outdoor air,” Ward said.

Ward said his program can afford the higher heating bills, at least for now, because of past savings from reduced energy use. Still, cost is an impediment to a more extensive revamp: Ward would like to install more efficient air filters, but the buildings — some of which are 30 years old — would have to be retrofitted to accommodate them.

Simply hiring a consultant to assess a building’s ventilation needs can cost from hundreds to thousands of dollars. And high-efficiency air filters can cost twice as much as standard ones.

Businesses also must be wary of companies that market pricey but unproven cleaning systems. A 2021 KHN investigation found that more than 2,000 schools across the country had used pandemic relief funds to purchase air-purifying devices that use technology that’s been shown to be ineffective or a potential source of dangerous byproducts.

Meghan McNulty, an Atlanta mechanical engineer focused on indoor air quality, said building managers often can provide cleaner air without expensive renovations. For example, they should ensure they are piping in as much outdoor air as required by local codes and should program their daytime ventilation systems to run continuously, rather than only when heating or cooling the air. She also recommends that building managers leave ventilation systems running into the evening if people are using the building, rather than routinely turning them down.

Some local governments have given businesses and residents a boost. Agencies in Montana and the San Francisco Bay area last year gave away free portable air cleaners to vulnerable residents, including people living in homeless shelters. All the devices use HEPA filters, which have been shown to remove coronavirus particles from the air.

In Washington state, the public health department for Seattle and King County has drawn on $3.9 million in federal pandemic funding to create an indoor air program. The agency hired staff members to provide free ventilation assessments to businesses and community organizations and has distributed nearly 7,800 portable air cleaners. Recipients included homeless shelters, child care centers, churches, restaurants, and other businesses.

Although the department has run out of filters, staff members still provide free technical assistance, and the agency’s website offers extensive guidance on improving indoor air quality, including instructions for turning box fans into low-cost air cleaners.

“We did not have an indoor air program before covid began,” said Shirlee Tan, a toxicologist for Public Health-Seattle & King County. “It’s been a huge gap, but we didn’t have any funding or capacity.”

Allen, who has long championed “healthy buildings,” said he welcomes the new emphasis on indoor air, even as he and others are frustrated it took a pandemic to jolt the conversation. Well before covid brought the issue to the fore, he said, research was clear that improved ventilation correlated with myriad benefits, including higher test scores for kids, fewer missed school days, and better productivity among office workers.

“This is a massive shift that is, quite honestly, 30 years overdue,” Allen said. “It is an incredible moment to hear the White House say that the indoor environment matters for your health.”

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This Final Fantasy VII Buster Sword clock prevents you from casting snooze

Are a Final Fantasy VII fan? Tired of oversleeping? Don’t want to use your phone as an alarm lest you get sucked into doomscrolling? Well, do I ever have the solution for you: a standalone digital clock fashioned after Final Fantasy VII’s iconic Buster Sword.

The miniature replica of Cloud Strife’s ridiculously large sword — specifically, the version in Final Fantasy VII Remake — is set at an angle reminiscent of how you see it on the game’s main menu screen. The time is illuminated prominently thanks to a display on the sword’s blade, and the materia near the hilt light up, too.

A closer look at the clock. Wonder what materia those are.
Image: Square Enix

If you like Final Fantasy VII Remake’s music — like me — you’ll be pleased to know that you can set five of the game’s best songs as your alarm:

  • Main Theme of FFVII — Sector 7 Undercity
  • Let the Battles Begin! — A Merc’s Job
  • The Airbuster (a remix of the original FF7’s boss battle theme that totally rips)
  • Aerith’s Theme — Home Again
  • One-Winged Angel — Rebirth

If you want to get an idea of what the music sounds like on the clock’s speakers, check out this video from Square Enix. The sound quality doesn’t seem great, but it might be worth dealing with so that Sephiroth’s theme song is the first thing you hear every morning.

Before you get ready to drop some gil on the clock, there are a few not-so-good things I should mention. For one thing, the clock costs… $199.99. If you put money down now, you’re only preordering the clock ahead of an expected January 2023 release date. According to Square’s website, the clock only shows 24-hour time. And you better hope that the weak-sounding speakers can fully wake you up, because the clock is also missing a snooze button.

But, if you’re willing to wait, really want to own a miniature replica of Cloud’s Buster Sword, and are okay living dangerously without a snooze button, you might want to put in your preorder now. While you wait, perhaps your dreams will be filled with the classic songs of Final Fantasy VII — soon enough, you’ll be able to hear them from the official clock, too.

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Special ultraviolet light prevents indoor transmission of airborne pathogens without harming humans: study

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The light at the end of the tunnel for the COVID-19 pandemic might just be overhead.

A new study shows a hands-off approach using ultraviolet light, called far-UVC light, reduced transmission of indoor airborne pathogens by more than 98% in less than five minutes, according to a recent statement.

“Far-UVC rapidly reduces the amount of active microbes in the indoor air to almost zero, making indoor air essentially as safe as outdoor air,” said co-author Dr. David Brenner, director of the Center for Radiological Research at Columbia University Vagelos College of Physicians and Surgeons. 

PERMANENT DAYLIGHT SAVING TIME MAY BE HARMFUL TO OUR HEALTH, EXPERTS SAY

“Using this technology in locations where people gather together indoors could prevent the next potential pandemic.” 

The joint study by scientists at Columbia University and in the U.K. suggests far-UVC light installed in ceiling lamps can reduce the risk of the next pandemic by effectively reducing airborne indoor transmission of infectious diseases known to cause major outbreaks, such as COVID-19 or influenza.

But the statement notes that far-UVC is a relatively new technology.

Although it’s been known for years that ultraviolet C light (UVC) has properties to destroy germs, its use has been largely limited because it can cause sunburns, skin cancers as well as harm people’s eyes, so its usage has been limited primarily to sterilizing medical equipment, the statement said.

But almost 10 years ago, scientists at Columbia University proposed that a different type of UVC light, called far-UVC light, could destroy germs as efficiently as conventional UVC light without the harmful side effects, because the light’s shorter wavelength does not allow it to penetrate human skin or eye cells, per the statement. 

Studies over the past decade confirmed far-UVC kills airborne bacteria and viruses without damaging living tissue as the germs are much smaller than human cells.
(iStock)

Studies over the past decade confirmed far-UVC kills airborne bacteria and viruses without damaging living tissue as the germs are much smaller than human cells, but the studies up to this point were confided in experimental chambers that never mimicked the real-world setting, according to the press release.

LONG COVID SYMPTOMS MAY DEPEND ON THE VARIANT A PERSON CONTRACTED

The current study tested the efficacy of far-UVC light in a chamber the size of a large indoor room that had an equivalent ventilation rate as a typical home or office, which is approximately three air changes per hour.

Researchers continuously sprayed a bacteria called Staphylococcus aureus until the concentration of the microbes stabilized, then turned on overhead far-UVC lamps.

They choose this particular bacteria versus coronavirus, because it is slightly less sensitive to far-UVC light, so the researchers could create a conservative model.

Kecia Harris, with the environmental services department, cleans the room of a patient fighting the coronavirus at Our Lady of Angels Hospital in Bogalusa, La., Monday, August 9, 2021.
((Chris Granger/The Advocate via AP))

The study discovered not only the light inactivated more than 98% of the airborne bacteria in only five minutes, but also was able to keep the level of bacteria in the air low over time as microbes continued to be sprayed in the room.

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“Far-UVC light is simple to install, it’s inexpensive, it doesn’t need people to change their behavior, and evidence from multiple studies suggests it may be a safe way to prevent the transmission of any virus, including the COVID virus and its variants, as well as influenza and also any potential future pandemic viruses,” Brenner said.

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‘First-of-its-kind’ nasal spray that prevents COVID-19 could be available this year

ITHACA, N.Y. – A nasal spray that blocks COVID-19 infection and treats people who are already sick could be available within the next six months, according to researchers at Cornell University. Their study discovered a small molecule that people can spray into their noses which prevents COVID from infecting human cells.

In experiments on lab cells and in mice, researchers found that the molecule N-0385 can both protect against infection in healthy individuals and eases symptoms in patients using the spray within 12 hours of exposure to COVID. For humans, the team believes this could soon become a new coronavirus treatment that only requires a few daily doses.

“There are very few, if any, small molecule antivirals that have been discovered that work prophylactically to prevent infection,” explains Hector Aguilar-Carreno, associate professor of virology in the Department of Microbiology and Immunology in the College of Veterinary Medicine, in a university release. “A TMPRSS2 Inhibitor ACTS as a pan-SARS-CoV-2 prophylactic and therapeutic.”

“This is the first of its kind,” Aguilar-Carreno adds. “One advantage is that it works early in the infection, even after someone has already acquired the virus.”

Researchers add that they tested the nasal spray against the original COVID strain and the Delta variant. Although they didn’t examine its effectiveness against the more recent Omicron variant, the Cornell team is optimistic the results will remain the same.

Ready for use in 6 months?

The researchers developed this molecule in collaboration with a team from Université de Sherbrooke in Quebec. A California-based company, EBVIA Therapeutics, Inc., is now raising funds so scientists can start human trials and eventually begin drug development and mass production of the spray.

Study authors say if all of that comes together and the human trials are successful, the nasal spray could apply for and receive FDA emergency-use approval within six months.

“The N-0385 therapy is simpler and less expensive to mass produce than other types of COVID-19 treatments, such as monoclonal antibodies,” Aguilar-Carreno says.

How does the molecule work?

Coronaviruses use the now-infamous spike protein to grab and infect a patient’s cells. To do that, the virus binds to a receptor on the surface of a healthy cell. During their study, researchers targeted a specific enzyme, TMPRSS2, which plays a key role in allowing the spike to fuse with the cell membrane.

The team identified a number of small molecules, including N-0385, which might be able to disable TMPRSS2’s cell-infecting abilities. Scientists examined each molecule’s ability to knock out TMPRSS2, first in lab experiments using human respiratory cells and later in genetically engineered mice.

Researchers altered the mice to carry human receptors on their cells, so the team could see if N-0385 could prevent infection before, during, and after exposure to COVID-19. All of those tests revealed that the intranasally introduced molecule works at stopping weight loss in mice — a key sign of infection in these animals. For mice exposed to the virus before taking the nasal spray, it kept them from dying during the experiment.

The study is published in the journal Nature.



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New Male Birth Control Pill Effectively Prevents Pregnancy – Without Side Effects

Women have many choices for birth control, ranging from pills to patches to intrauterine devices, and partly as a result, they bear most of the burden of preventing pregnancy. But men’s birth control options — and, therefore, responsibilities — could soon be expanding. Today, scientists report a non-hormonal male contraceptive that effectively prevents pregnancy in mice, without obvious side effects.

The researchers presented their results this week at the spring meeting of the American Chemical Society (ACS). ACS Spring 2022 is a hybrid meeting that was held virtually and in-person March 20-24, with on-demand access available March 21-April 8. The meeting features more than 12,000 presentations on a wide range of science topics.

Currently, men have only two effective options for birth control: male condoms and vasectomy. However, condoms are single-use only and prone to failure. In contrast, vasectomy — a surgical procedure — is considered a permanent form of male sterilization. Although vasectomies can sometimes be reversed, the reversal surgery is expensive and not always successful. Therefore, men need an effective, long-lasting but reversible contraceptive, similar to the birth control pill for women.

A non-hormonal male contraceptive (known as YCT529; structure shown here) prevents pregnancy in mice by blocking a vitamin A receptor, with no obvious side effects. Credit: Md Abdullah Al Noman

“Scientists have been trying for decades to develop an effective male oral contraceptive, but there are still no approved pills on the market,” says Md Abdullah Al Noman, who is presenting the work at the meeting. Most compounds currently undergoing clinical trials target the male sex hormone testosterone, which could lead to side effects such as weight gain, depression and increased low-density lipoprotein (known as LDL) cholesterol levels. “We wanted to develop a non-hormonal male contraceptive to avoid these side effects,” says Noman, a graduate student in the lab of Gunda Georg, Ph.D., at the University of Minnesota.

To develop their non-hormonal male contraceptive, the researchers targeted a protein called the retinoic (function(d, s, id){ var js, fjs = d.getElementsByTagName(s)[0]; if (d.getElementById(id)) return; js = d.createElement(s); js.id = id; js.src = "https://connect.facebook.net/en_US/sdk.js#xfbml=1&version=v2.6"; fjs.parentNode.insertBefore(js, fjs); }(document, 'script', 'facebook-jssdk'));

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New BioAge Drug Prevents Death From COVID-19 in Old Mice by Reversing Immune Aging

A Phase 2 clinical trial is testing the new drug’s ability to reduce mortality in older people hospitalized with (function(d, s, id){ var js, fjs = d.getElementsByTagName(s)[0]; if (d.getElementById(id)) return; js = d.createElement(s); js.id = id; js.src = "https://connect.facebook.net/en_US/sdk.js#xfbml=1&version=v2.6"; fjs.parentNode.insertBefore(js, fjs); }(document, 'script', 'facebook-jssdk'));

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Mother shields baby daughter from shelling, prevents her being harmed, Ukrainian hospital says

While Ukraine’s army reported little in the way of offensive operations by Russian forces around Kyiv and in parts of the south on Saturday, further east fighting continued to rage.

Two children were killed in the town of Rubizhne after being pulled from the rubble of a residential building pummeled by Russian artillery fire, the emergency services said. 

A woman also died in the same building collapse; her daughter survived and was in a stable condition.

Some context: Rubizhne is part of a cluster of small towns and villages that remain in Ukrainian hands but lie close to two breakaway pro-Russian statelets inside eastern Ukraine.

The Ukrainian army’s most recent assessment of the war makes clear they are seen as a current focus of Russia’s campaign in the east — to link the two strongholds around Luhansk and Donetsk with territorial gains made to the northwest in the region around Kharkiv.

Saturday’s daily update from the army’s central command — released in the early afternoon — reported a series of Russian offensives with “the main efforts focused on attempts to capture Severodonetsk, Rubizhne and Popasna.”

Further deaths and destruction: On Friday, four people were killed and ten others injured as Russian artillery opened up across a series of communities in the region, local Ukrainian authorities said. 

Regional head Serhii Haidai said a total of 54 buildings had been hit, including 19 apartment blocks and two health care centers.

Some 23 towns and villages were without gas supplies and 26 were without electricity by the day’s end.

Many of those wounded in recent days were among 700 people evacuated through a humanitarian corridor on Saturday, Haidai reported. 

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Volunteers wanted for nasal spray trial developed by Melbourne scientists that prevents Covid

Nasal spray developed by Australian scientists STOPS cancer patients catching Covid with a bigger trial to find if it can be the next weapon to fight the pandemic

  • Trial for Melbourne-developed nasal spray for cancer patients will be expanded
  • None of the 175 patients who have taken part so far have contracted Covid-19
  • Scientists are seeking more volunteers to take part in Melbourne and Sydney
  • Anyone with a past or current cancer diagnosis is eligible to take part in the trial










A trial for a nasal spray that has prevented cancer patients getting Covid-19 could be a new weapon to fight the pandemic.

Some 175 patients have tested the drug by taking daily doses of a nasal spray containing cancer drug interferon developed by scientists at the Peter MacCallum Cancer Centre and the Royal Melbourne Hospital. 

None of the participants in the C-SMART trial have contracted Covid so far, despite several waves of the virus plunging Melbourne into six lockdowns.

Scientists are seeking more volunteers to take part in the free trial, which will be expanded to Austin and St Vincent’s hospitals in Melbourne, along with Westmead Hospital in western Sydney.

A trial for an Australian developed nasal spray that has prevented cancer patients from getting Covid-19 will be expanded across Melbourne and into Sydney (stock image)

Anyone with a past or current cancer diagnosis is eligible to take part in the four month trial. 

Scientists hope the nasal spray will be an extra protection for vulnerable patients until better preventions are developed.

‘We have not had any patient on the trial actually report back to us that they have developed Covid infection,’ National Centre for Infections in Cancer director Professor Monica Slavin told the Herald Sun.

‘But we have had about 10 per cent of people on the trial sending in a swab due to some sort of viral illness.

‘We know that there are groups of patients, because of the immune system being suppressed, that don’t make a good response to the vaccination.’

But it hasn’t all been smooth sailing for the trial, which began a year ago.

None of the 175 cancer patients who have taken a daily dose of the nasal spray have contracted Covid-19 (pictured, health workers at a Melbourne testing clinic)

Scientists were forced to press pause on the trial for five months earlier this year when access to chemicals and sending samples of the drug for testing were hampered by international border closures.

The expanded trial will determine whether the drug can also prevent other respiratory viral illnesses.

Studies have shown cancer patients make up 10 per cent of severe Covid-19 cases, and about 20 per cent of those who die from it, according to the trial’s website.

They are also more likely to rapidly develop severe infections and be admitted to ICU compared to cases without cancer. 

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Sleep training for adults prevents depression, study finds

“What is exciting about these findings is that they are among the first to demonstrate that treating insomnia with a behavioral strategy, not a pill, can prevent the development of depression in older adults,” said sleep specialist Wendy Troxel, a senior behavioral scientist at RAND Corporation, who was not involved in the study.

The study’s findings are “highly significant” because major depression is very common among older adults and “is associated with an increased risk of cognitive decline, disability, suicide and all-cause mortality,” Troxel added.

Adults in the randomized clinical trial who received cognitive behavior therapy for their insomnia were two times less likely to develop depression, Irwin said, adding that if remission from insomnia was sustained for three years, “there was an 83% reduction in the likelihood of developing depression.”

“That’s why this study is so important,” Irwin said. “We have shown that we can actually target insomnia with cognitive behavior therapy and prevent depression from occurring.”

Therapist involvement was key

The study, published Wednesday in the journal JAMA Psychiatry, randomly split adults over age 60 with insomnia but without depression into two groups. Every week for two months, a control group received eight weeks of basic sleep education, which taught sleep hygiene, characteristics of healthy sleep, sleep biology, and how stress can impact sleep. But there was no one-on-one training, Irwin said: “They had to take that information and figure out how to use it without our help.”

The other group received a form of behavioral sleep training called CBT-1, administered in person in a group setting by trained therapists for eight weeks.

“The benefit of this treatment approach is that it used the most evidence-based behavioral treatment for insomnia, CBT-I, which has been proven to be as effective, longer lasting, and (have) fewer side effects than sleep medications — which can be particularly problematic in older adults,” Troxel said.

CBT-I has five components: Stimulus control, sleep restriction, sleep hygiene, relaxation and cognitive behavioral therapy. Sleep hygiene and relaxation involve good sleep habits — going to bed and getting up at the same time each day, eliminating blue light and noise, taking warm baths or doing yoga for relaxation, and keeping the bedroom cool and free of electronic devices.

Stimulus control involves “getting people to get out of bed when they’re not able to sleep,” Irwin said. Most people stay in bed, fretting about not falling asleep, which then turns the bed into a negative space, he explained. Instead, people are taught to get up after 10 minutes of tossing and turning, do quiet, non-stimulating activites, and “not to come back to bed until they are sleepy.”

Sleep restriction involves limiting time in bed to only the period a person sleeps, plus 30 minutes. It’s another way to get people with insomnia to get up instead of lying in bed awake.

Cognitive therapy works to disrupt “dysfunctional thoughts and beliefs about sleep,” Irwin said, such as “I can never sleep,” or “I might die if I don’t sleep tonight.” A therapist works with the person to counter such illogical thinking, easing them back into a more realistic mindset that will allow them to relax and see the bed as a welcoming place.

“I really think a group setting is also really important,” Irwin said, “because hearing other people’s difficulties and how they are solving them can often help inform you about something that you may be dealing with.”

A means to an end

At the end of two months, treatment ended, with no further intervention. However, the study then followed the 291 people for three years, checking in each month to ask about symptoms of depression.

The group that received CBT-I training with the help of a sleep coach often kept the training going in their own lives, Irwin said, with good results: “About a third of the people were still free of insomnia at the end of the three-year study.”

The group which received sleep education did show “modest effects in improving and treating insomnia but (the improvements) were not durable. They didn’t last,” Irwin said.

“That’s why CBT-I is so effective in person, because the therapist is helping that individual navigate and negotiate with themselves — and it can be really hard work,” Irwin added. “I believe that’s also why CBT-I apps or online tools often don’t work — people get frustrated, disappointed or angry at themselves, and they basically stop the work.”

The study’s results show “a completely new and innovative way” of tackling the growing problem of depression, wrote Pim Cuijpers, a professor of Clinical Psychology at the Vrije Universiteit Amsterdam, and Dr. Charles Reynolds, a professor in geriatric psychiatry at the University of Pennsylvania Medical Center, in an editorial published alongside the study.

“The stigma associated with major depression as a mental disorder is one of the main reasons for not seeking treatment,” wrote Cuijpers and Reynolds, who were not involved in the study.

“This major finding offers exciting new opportunities for the prevention field and opens a new field of research into indirect preventive interventions for avoiding the stigma of mental disorders.”

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Chandrayaan 2: Isro prevents Chandrayaan-2 collision with Nasa’s LRO | India News

Nearly a month after the actual manoeuvre, the Indian Space Research Organisation (Isro) has disclosed that Chandrayaan-2 orbiter had to perform a collision avoidance manoeuvre (CAM) to avoid colliding with NASA’s Lunar Reconnaissance Orbiter (LRO), in October.
“A very close conjunction between the Chandrayaan-2 Orbiter and the LRO was expected to occur on October 20 near the Lunar North pole. Over a span of one week prior to the conjunction, analyses by both Isro and JPL/NASA consistently showed that the radial separation between the spacecraft would be less than 100 m and the closest approach distance would be only about 3 km at the aforementioned time of closest approach,” an Isro statement reads.

It added that both the agencies deemed that the situation warranted a CAM to mitigate the close approach risk, and it was mutually agreed that Isro’s orbiter would undergo the same.
“The manoeuvre was scheduled on October 18, 2021. It was designed to ensure a sufficiently large radial separation at the next closest conjunction between the spacecraft. The CAM was executed nominally at 8.22pm (IST). After orbit determination with post-manoeuvre tracking data, it was reconfirmed that there would be no further close conjunctions with LRO in the near future with the achieved orbit,” Isro said.
Chandrayaan-2 and LRO orbit Moon in a nearly polar orbit and hence, both the spacecraft come close to each other over the Lunar poles.
“…It is common for satellites in Earth Orbit to undergo CAMs to mitigate collision risk due to space objects including space debris and operational spacecraft. Isro monitors such critical close approaches and execute CAMs for its operational satellites whenever risk is assessed to be critical. However, this is the first time such a critically close conjunction was experienced for a space exploration mission of Isro,” the space agency said.
It added that the event highlights the importance of continual assessment of close approach situations for lunar and martian missions, and the fact that effective mitigation of close approach risk involves close coordination and synergy among different space agencies.



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