- Richard Gadd on ‘Baby Reindeer’ Phenomenon, Losing Anonymity and What He Won’t Ever Comment on Again Hollywood Reporter
- The True Story Behind ‘Baby Reindeer’: Where Is Martha Now? PEOPLE
- Richard Gadd Shocked ‘Baby Reindeer’ Was Not Just “Little Cult Artistic Gem” As Interview With Real-Life Martha Is Watched By Millions Deadline
- ‘Baby Reindeer’ Actor Richard Gadd Has ‘Toxic Empathy’ Toward Stalker Business Insider
- Richard Gadd says Baby Reindeer crew cried while filming traumatic fourth episode The Independent
Tag Archives: Phenomenon
Global cancer phenomenon: It’s not just America… the UK, Japan, South Africa and Australia are among dozens of countries suffering mystery spikes of all different kinds of tumors in young people – Daily Mail
- Global cancer phenomenon: It’s not just America… the UK, Japan, South Africa and Australia are among dozens of countries suffering mystery spikes of all different kinds of tumors in young people Daily Mail
- Why are so many young people getting cancer? What the data say Nature.com
- Orange County leads Southern California in cancer rates among 18 to 49-year-olds: report KTLA Los Angeles
- Orange County leading a grim trend: Cancer among younger people OCRegister
- Orange County hospital sees troubling increase in cancer cases among young adults CBS Los Angeles
NFL Marketing Exec On Taylor Swift-Travis Kelce Viral Phenomenon: “People Think We May Have Had Something To Do With It – Absolutely Not, We Knew Nothing” – Deadline
- NFL Marketing Exec On Taylor Swift-Travis Kelce Viral Phenomenon: “People Think We May Have Had Something To Do With It – Absolutely Not, We Knew Nothing” Deadline
- Travis Kelce spills on his NYC weekend with Taylor Swift CNN
- Travis, Jason Kelce joke about Taylor Swift meeting their dad; Chiefs star denies security guard push Fox News
- Taylor Swift and Travis Kelce Are ‘All In’ and He Plans to Visit Her on Eras International Tour (Exclusive) Entertainment Tonight
- Travis Kelce’s ‘Super’ Halloween Costume Made Fans Fall in Love With Him Years Ago Parade Magazine
- View Full Coverage on Google News
‘The Beanie Bubble’ Review: Powerhouse Actress Trio Banks, Snook And Viswanathan Take On Billionaire Boss Zach Galifianakis In Sly And Smart Biopic Of ’90s Toy Phenomenon – Deadline
- ‘The Beanie Bubble’ Review: Powerhouse Actress Trio Banks, Snook And Viswanathan Take On Billionaire Boss Zach Galifianakis In Sly And Smart Biopic Of ’90s Toy Phenomenon Deadline
- Inside the Beanie Baby Nostalgia Boom The Ringer
- The Beanie Bubble Review JoBlo.com
- The Beanie Bubble review – plushie-craze toy story goes down the cute route The Guardian
- ‘The Beanie Bubble’ Review: Zach Galifianakis and Elizabeth Banks in a Fun but Familiar Tale of a ’90s Toy Craze Hollywood Reporter
- View Full Coverage on Google News
Rare ‘warped’ supernova revealed through space-time phenomenon predicted by Einstein – Livescience.com
- Rare ‘warped’ supernova revealed through space-time phenomenon predicted by Einstein Livescience.com
- Astronomers capture rare “bizarre” star explosion that could help uncover “the mysteries of the universe” CBS News
- Einstein’s Theory in Action: Supernova Explosion Revealed by Rare “Cosmic Magnifying Glasses” SciTechDaily
- A tiny galaxy brightening up a distant supernova Nature.com
- Seeing quadruple: Rare gravitational lensing warps light from explosion of distant dying star : Big Island Now Big Island Now
- View Full Coverage on Google News
Rare ‘warped’ supernova revealed through space-time phenomenon predicted by Einstein – Yahoo Life
- Rare ‘warped’ supernova revealed through space-time phenomenon predicted by Einstein Yahoo Life
- Astronomers capture rare “bizarre” star explosion that could help uncover “the mysteries of the universe” CBS News
- Einstein’s Theory in Action: Supernova Explosion Revealed by Rare “Cosmic Magnifying Glasses” SciTechDaily
- A tiny galaxy brightening up a distant supernova Nature.com
- Seeing quadruple: Rare gravitational lensing warps light from explosion of distant dying star : Big Island Now Big Island Now
- View Full Coverage on Google News
‘A Bear On Mars?’ NASA Spots Trippy Phenomenon On Planet’s Surface
Scientists looking at the surface of Mars have spotted what looks like a bear staring back at them.
A camera on NASA’s Mars Reconnaissance Orbiter took a photo of the formation on Dec. 12. It was shared Wednesday by the University of Arizona, which operates the camera.
A hill with a V-shaped collapse structure forms the bear’s nose and a circular fracture pattern creates the head, the university’s Lunar and Planetary Laboratory explained in the blog for its High Resolution Imaging Science Experiment (HiRISE) camera.
“The circular fracture pattern might be due to the settling of a deposit over a buried impact crater. Maybe the nose is a volcanic or mud vent and the deposit could be lava or mud flows?” it said.
This is due to a tendency for the human brain to try and see recognizable shapes in objects or data that are otherwise not familiar to us, known as pareidolia.
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Alyssa Thompson: The teenage phenomenon who could be US soccer’s next great
CNN
—
Described by her new team Angel City as a “generational player,” teenage sensation Alyssa Thompson made history on Thursday by becoming the first high school student to be drafted in National Women’s Soccer League history.
Being drafted No. 1 overall is another big step in what has been an already impressive fledgling career.
Thompson already boasts two caps for the US Women’s National Team (USWNT), having made her international debut aged just 17 in a friendly against European champion England in September at a sold out Wembley Stadium.
Now 18 years old, Thompson has been a highly touted prospect for years, with her abilities on the field evident from an early age.
In 2020, she and her younger sister, Gisele, moved to play for the Total Futbol Academy, a boys’ club in the Major League Soccer’s academy system, MLS NEXT.
Back in May 2022, the Thompson sisters secured a historic multiyear deal to become the first high school athletes to sign a name, image and likeness deal with Nike.
A Los Angeles native, Thompson was named the 2021 High School Soccer Player of the Year after scoring 48 goals in 18 games with Harvard-Westlake School, where she is still a senior.
Thompson is also no slouch, competing in the 100 meters during high school and recording top 10 times in the state of California during her three years running track.
According to Angel City, she recorded the sixth fastest time in the state in 2022.
Able to play in all three positions across the front line, as well as in midfield, Thompson was able to showcase her talents to Angel City last year when she joined the club for preseason training camp.
“Training with the full team and being in that environment, I thought: ‘Wow, I can do this,’” she told the Angel City website.
Thompson had verbally agreed to play for Stanford next year, according to ESPN, but chose to forgo her college eligibility and declared for the draft last week, a stipulation for high school athletes if they want to be considered for the NWSL draft.
ESPN reports that Thompson will complete her senior year of high school at Harvard-Westlake by taking online classes once the NWSL season gets underway on March 25, but will attend classes at the school when her schedule allows.
According to ESPN, Thompson and her parents said studying for a degree remains a priority alongside pursuing her professional soccer career, something Angel City said it will help Thompson organize next year.
“From the beginning it’s always been something that if I’m going to go pro, I’m still going to get an education,” Thompson told ESPN. “I want to continue to get better, and since there’s opportunity to still go to college, why wouldn’t I do it?”
Thompson’s historic selection at No. 1 in the draft continues her meteoric rise through the US Soccer ranks and she will now regularly be playing in front of almost 20,000 fans at Angel City’s Banc of California Stadium.
And with the Women’s World Cup set to begin on July 20 in Australia and New Zealand, don’t be surprised if Thompson earns herself a place in the USWNT squad for the tournament.
Mysterious Quantum Phenomenon Lets Us Peek Inside an Atom’s Heart : ScienceAlert
Silently churning away at the heart of every atom in the Universe is a swirling wind of particles that physics yearns to understand.
No probe, no microscope, and no X-ray machine can hope to make sense of the chaotic blur of quantum cogs whirring inside an atom, leaving physicists to theorize the best they can based on the debris of high-speed collisions inside particle colliders.
Researchers now have a new tool that is already providing them with a small glimpse into the protons and neutrons that form the nuclei of atoms, one based on the entanglement of particles produced as gold atoms brush past each other at speed.
Using the powerful Relativistic Heavy Ion Collider (RHIC) at the US Department of Energy’s Brookhaven National Laboratory, scientists have shown how it’s possible to glean precise details on the arrangement of gold’s protons and neutrons using a kind of quantum interference never before seen in an experiment.
“This technique is similar to the way doctors use positron emission tomography (PET scans) to see what’s happening inside the brain and other body parts,” says physicist James Daniel Brandenburg, formerly a Brookhaven researcher and now a member of the STAR collaboration.
“But in this case, we’re talking about mapping out features on the scale of femtometers – quadrillionths of a meter – the size of an individual proton.”
In textbook terms, the anatomy of a proton can be described as a trio of fundamental building blocks called quarks bound together by the exchange of a force-carrying particle called a gluon.
Were we to zoom in and observe this collaboration firsthand, we’d see nothing so neat. Particles and antiparticles pop in and out of existence in a seething foam of statistical madness, where the rules on particle distribution are anything but consistent.
Putting constraints on the movements and momenta of quarks and gluons requires some clever thinking, but hard evidence is what physicists really desire.
Unfortunately, simply shining a light onto a proton won’t result in a snapshot of its moving parts. Photons and gluons play by very different rules, meaning they are effectively invisible to one another.
There is a loophole, however. Imbued with enough energy, waves of light can occasionally churn up pairs of particles that sit on the brink of existence before vanishing again, among which are quarks and antiquarks.
Should this spontaneous emergence occur within earshot of an atom’s nucleus, the poltergeist flicker of opposing quarks could mix with the swirling volleys of gluons and temporarily form a conglomerate known as a rho particle, which in a fraction of a second shatters into a pair of charged particles called pions.
Those pairs consist of a positive pion, composed of an up quark and down antiquark, and a negative pion made up of a down quark and an up antiquark.
Tracing the path and properties of pions formed this way might tell us something about the hornet’s nest it was born in.
A couple of years ago, researchers at RHIC discovered it was possible to use the electromagnetic fields surrounding gold atoms moving at high speeds as a source of photons.
“In that earlier work, we demonstrated that those photons are polarized, with their electric field radiating outward from the center of the ion,” says Brookhaven physicist Zhangbu Xu.
“And now we use that tool, the polarized light, to effectively image the nuclei at high energy.”
When two gold atoms barely avoid crashing as they circle the collider in opposing directions, the photons of light passing through each nucleus can give birth to a rho particle and, therefore, pairs of charged pions.
The physicists measured the pions ejected from the passing gold nuclei and showed they did indeed have opposing charges. An analysis of the wave-like properties of the shower of particles showed signs of interference that could be traced back to the light’s polarization and hinted at something far less expected.
In typical applied and experimental quantum settings, entanglement is observed between the same kinds of particles: electrons with electrons, photons with photons, and atoms with atoms.
The patterns of interference observed in the analysis of the particles produced in this experiment could only be explained by the entanglement of non-identical particles – a negatively charged pion with a positively charged pion.
Though far from a theoretical anomaly, it’s far from an everyday occurrence in the laboratory, amounting to the first experimental observation of entanglement involving dissimilar particles.
Back-tracing the entangled interference patterns to the gold nuclei, the physicists could tease out a two-dimensional portrait of its gluon distribution, providing new insights into the structures of nuclear particles.
“Now we can take a picture where we can really distinguish the density of gluons at a given angle and radius,” says Brandenburg.
“The images are so precise that we can even start to see the difference between where the protons are and where the neutrons are laid out inside these big nuclei.”
This research was published in Science Advances.
Rare Genetic Phenomenon Linked to Neuron Function and Schizophrenia
Summary: People with schizophrenia have significantly higher rates of tandem repeats in their genome, up to 7% more than in people without the mental health disorder. The genes were primarily found in genes crucial to brain function.
Source: UNC
In our cells, the language of DNA is written, making each of us unique. A tandem repeat occurs in DNA when a pattern of one or more nucleotides—the basic structural unit of DNA coded in the base of chemicals cytosine (C), adenine (A), guanine (G) and thymine (T)—is repeated multiple times in tandem. An example might be: CAG CAG CAG, in which the pattern CAG is repeated three times.
Now, using state-of-the-art whole-genome sequencing and machine learning techniques, the UNC School of Medicine lab of Jin Szatkiewicz, Ph.D., associate professor of genetics, and colleagues conducted one of the first and the largest investigations of tandem repeats in schizophrenia, elucidating their contribution to the development of this devastating disease.
Published in the journal Molecular Psychiatry, the research shows that individuals with schizophrenia had a significantly higher rate of rare tandem repeats in their genomes—7% more than individuals without schizophrenia. And they observed that the tandem repeats were not randomly located throughout the genome; they were primarily found in genes crucial to brain function and known to be important in schizophrenia, according to previous studies.
“We think this discovery opens doors for future functional studies on the precise biological mechanism of such variants,” said Szatkiewicz, who is also adjunct assistant professor of psychiatry.
“Understanding the biological cause of schizophrenia will enable future development of diagnostic tests, effective pharmaceuticals, and personalized treatments.”
Tandem repeats usually don’t have negative health implications. However, based on the location of tandem repeats in the genome and how long they are, they can contribute to disease. For example, Huntington’s disease is caused by a tandem repeat in the HTT gene that has been abnormally expanded. Onset of the disease will happen once the sequence of cytosine-adenine-guanine (CAG) repeats more than 36 times on the HTT gene.
The longer repeat expansions lead to abnormal protein products with an extended track of glutamine that is toxic to brain cells. These repeats are inherited and tend to grow longer and longer in successive generations with increasing disease severity or decreasing age of onset.
In their current study, Szatkiewicz and her team looked at the entire genomes of 2,100 individuals to find tandem repeats that looked abnormally long and were unique or rare. Because all participants provided access to their medical records, the team was able to compare these long and rare repeat DNA sequence samples from people who had schizophrenia versus samples from people in the study who didn’t. This allowed the researchers to determine which of these tandem repeats may be involved with the development of schizophrenia.
Using gene network analysis, the authors of this study demonstrated that genes with rare tandem repeats found in schizophrenia primarily impact synaptic and neuronal signaling functions.
In addition, these genes are highly evolutionarily conserved, indicating important biological functions and therefore the significant impact that tandem repeats might exert.
The UNC School of Medicine researchers then collaborated with scientists from The Hospital for Sick Children in Toronto to see if this increased level of rare tandem variants would also be found in another independently collected group of samples.
The Szatkiewicz findings were replicated in the Canadian investigation, indicating that this newly discovered link between tandem repeats and schizophrenia is quite strong.
“We think this is an important study,” said co-senior author Ryan Yuen, Ph.D., senior scientist at the Hospital for Sick Children and assistant professor of molecular genetics at the University of Toronto. “We’re confident our work sheds significant light on the role of tandem repeat DNA mutations play in the development of schizophrenia.”
About this schizophrenia and genetics research news
Author: Press Office
Source: UNC
Contact: Press Office – UNC
Image: The image is in the public domain
See also
Original Research: Open access.
“Rare tandem repeat expansions associate with genes involved in synaptic and neuronal signaling functions in schizophrenia” by Jia Wen et al. Molecular Psychiatry
Abstract
Rare tandem repeat expansions associate with genes involved in synaptic and neuronal signaling functions in schizophrenia
Tandem repeat expansions (TREs) are associated with over 60 monogenic disorders and have recently been implicated in complex disorders such as cancer and autism spectrum disorder. The role of TREs in schizophrenia is now emerging. In this study, we have performed a genome-wide investigation of TREs in schizophrenia.
Using genome sequence data from 1154 Swedish schizophrenia cases and 934 ancestry-matched population controls, we have detected genome-wide rare (<0.1% population frequency) TREs that have motifs with a length of 2–20 base pairs. We find that the proportion of individuals carrying rare TREs is significantly higher in the schizophrenia group.
There is a significantly higher burden of rare TREs in schizophrenia cases than in controls in genic regions, particularly in postsynaptic genes, in genes overlapping brain expression quantitative trait loci, and in brain-expressed genes that are differentially expressed between schizophrenia cases and controls.
We demonstrate that TRE-associated genes are more constrained and primarily impact synaptic and neuronal signaling functions.
These results have been replicated in an independent Canadian sample that consisted of 252 schizophrenia cases of European ancestry and 222 ancestry-matched controls. Our results support the involvement of rare TREs in schizophrenia etiology.