Tag Archives: Phase

Opdivo (nivolumab) in Combination with Cisplatin-Based Chemotherapy Shows Overall Survival and Progression-Free Survival Benefit for Cisplatin-Eligible Patients with Unresectable or Metastatic Urothelial Carcinoma in the Phase 3 CheckMate -901 Trial – Bristol-Myers Squibb

  1. Opdivo (nivolumab) in Combination with Cisplatin-Based Chemotherapy Shows Overall Survival and Progression-Free Survival Benefit for Cisplatin-Eligible Patients with Unresectable or Metastatic Urothelial Carcinoma in the Phase 3 CheckMate -901 Trial Bristol-Myers Squibb
  2. Bristol Myers’ Opdivo stages comeback in bladder cancer, teeing up 2 ‘Merck’ showdowns FiercePharma
  3. Bristol Myers’ Opdivo extends survival in bladder cancer study Reuters
  4. First-line Nivolumab Plus Chemo Provides Survival Benefit in Metastatic Urothelial Carcinoma OncLive
  5. Study: Bladder Cancer Drug Extends Survival Newsmax

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Lilly’s next obesity drug just cut an average of 58 pounds—prompting an all-out phase 3 blitz – FierceBiotech

  1. Lilly’s next obesity drug just cut an average of 58 pounds—prompting an all-out phase 3 blitz FierceBiotech
  2. A new weight-loss drug dubbed the ‘triple G’ could be stronger than Ozempic, Wegovy, and Mounjaro — and as powerful as bariatric surgery Yahoo Life
  3. Eli Lilly (LLY) Weight-Loss Shot Gives Company’s Strongest Results in Trial Bloomberg
  4. Tirzepatide once weekly for the treatment of obesity in people with type 2 diabetes (SURMOUNT-2): a double-blind, randomised, multicentre, placebo-controlled, phase 3 trial The Lancet
  5. Triple–Hormone-Receptor Agonist Retatrutide for Obesity — A Phase 2 Trial | NEJM nejm.org
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Retatrutide, a GIP, GLP-1 and glucagon receptor agonist, for people with type 2 diabetes: a randomised, double-blind, placebo and active-controlled, parallel-group, phase 2 trial conducted in the USA – The Lancet

  1. Retatrutide, a GIP, GLP-1 and glucagon receptor agonist, for people with type 2 diabetes: a randomised, double-blind, placebo and active-controlled, parallel-group, phase 2 trial conducted in the USA The Lancet
  2. American Diabetes Association Highlights Novel Agent Retatrutide which Results in Substantial Weight Reduction in People with Obesity or Type 2 Diabetes During Late Breaking Symposium PR Newswire
  3. American Diabetes Association Highlights New Developments in Diabetes Technology Pharmacy Times
  4. American Diabetes Association presentation highlights innovations in technology for diabetic eye condition Ophthalmology Times
  5. Late Breaking Weight Loss Innovations: New Drug Therapies Shown to Offer Positive Outcomes for Obesity and Type 2 Diabetes Management PR Newswire
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Triple–Hormone-Receptor Agonist Retatrutide for Obesity — A Phase 2 Trial | NEJM – nejm.org

  1. Triple–Hormone-Receptor Agonist Retatrutide for Obesity — A Phase 2 Trial | NEJM nejm.org
  2. Lilly links oral drug to 15% weight loss, setting bar for Pfizer FierceBiotech
  3. A new weight-loss drug dubbed the ‘triple G’ could be stronger than Ozempic, Wegovy, and Mounjaro — and as powerful as bariatric surgery Yahoo Life
  4. Tirzepatide once weekly for the treatment of obesity in people with type 2 diabetes (SURMOUNT-2): a double-blind, randomised, multicentre, placebo-controlled, phase 3 trial The Lancet
  5. Novel Triple Agonist Nabs Biggest Weight Loss Yet in Obesity Trial Medpage Today
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Safety and immunogenicity of a single-shot live-attenuated chikungunya vaccine: a double-blind, multicentre, randomised, placebo-controlled, phase 3 trial – The Lancet

  1. Safety and immunogenicity of a single-shot live-attenuated chikungunya vaccine: a double-blind, multicentre, randomised, placebo-controlled, phase 3 trial The Lancet
  2. First Vaccine For Chikungunya—An Emerging Mosquito-Borne Threat—Nears After Promising Trial Results Forbes
  3. Valneva Reports Strong Phase III Chikungunya Vaccine Data After Merck’s Exit from Race BioSpace
  4. Positive results for potential first chikungunya vaccine – Wed, June 14 2023 The Jakarta Post
  5. Vaccine Candidate for Chikungunya Virus Safe and Effective Medpage Today
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Vertex-CRISPR drug posts phase 3 wins, secures PDUFA date – FierceBiotech

  1. Vertex-CRISPR drug posts phase 3 wins, secures PDUFA date FierceBiotech
  2. CRSP Stock Pops As FDA Sets December Data To Potentially OK Gene-Editing Drug | Investor’s Business Daily Investor’s Business Daily
  3. FDA Accepts Biologics License Applications for exagamglogene autotemcel (exa-cel) for Severe Sickle Cell Disease and Transfusion-Dependent Beta Thalassemia Yahoo Finance
  4. Gene Editing Race Between Editas and Vertex, CRISPR Heats Up BioSpace
  5. Editas posts early sickle cell data as it races to catch Vertex FierceBiotech
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Outpatient treatment of COVID-19 and incidence of post-COVID-19 condition over 10 months (COVID-OUT): a multicentre, randomised, quadruple-blind, parallel-group, phase 3 trial – The Lancet

  1. Outpatient treatment of COVID-19 and incidence of post-COVID-19 condition over 10 months (COVID-OUT): a multicentre, randomised, quadruple-blind, parallel-group, phase 3 trial The Lancet
  2. Common drug reduces long COVID, University of Minnesota study shows Star Tribune
  3. New study from UMN researchers says an existing drug is a promising treatment for long COVID MPR News
  4. Low-Dose Naltrexone Could Treat Long COVID Symptoms Verywell Health
  5. Study: Using a diabetes medication after testing positive for SARS-CoV-2 reduces risk of developing long COVID by 40% Medical Xpress
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Promising Phase 2 Trial Results for Pembrolizumab in Metastatic Brain Cancer – Neuroscience News

  1. Promising Phase 2 Trial Results for Pembrolizumab in Metastatic Brain Cancer Neuroscience News
  2. Study of immunotherapy for brain cancer metastases shows promising results News-Medical.Net
  3. Gene-edited and -engineered stem cell platform drives immunotherapy for brain metastatic melanomas Science
  4. New Weapon Against Brain Cancer: Gene Engineered Cell Therapy’s Two-Pronged Assault on Metastatic Melanomas SciTechDaily
  5. Scientists develop new immuno-therapeutic approach to target brain metastatic melanomas News-Medical.Net
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Tagrisso plus chemotherapy demonstrated strong improvement in progression-free survival for patients with EGFR-mutated advanced lung cancer in FLAURA2 Phase III trial – AstraZeneca

  1. Tagrisso plus chemotherapy demonstrated strong improvement in progression-free survival for patients with EGFR-mutated advanced lung cancer in FLAURA2 Phase III trial AstraZeneca
  2. AstraZeneca Tagrisso chemo combo cuts risk of lung cancer progression Seeking Alpha
  3. Immunotherapy Plus Chemo Improves Quality of Life in NSCLC Medscape
  4. AstraZeneca’s Tagrisso, chemo combination shows promise in lung cancer trial Reuters
  5. Docetaxel Plus Ramucirumab After Standard Frontline Treatment Elicits Responses in NSCLC OncLive
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Cognitive functional therapy with or without movement sensor biofeedback versus usual care for chronic, disabling low back pain (RESTORE): a randomised, controlled, three-arm, parallel group, phase 3, clinical trial – The Lancet

  1. Cognitive functional therapy with or without movement sensor biofeedback versus usual care for chronic, disabling low back pain (RESTORE): a randomised, controlled, three-arm, parallel group, phase 3, clinical trial The Lancet
  2. Innovative therapy brings hope to chronic lower back pain sufferers New Atlas
  3. Study offers fresh hope for people living with chronic back pain Medical Xpress
  4. New drug-free treatment offers long-term hope for Australians struggling with back pain | 7NEWS 7NEWS Australia
  5. Curtin University researchers say back pain treatment trial gives hope to millions ABC News
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