Tag Archives: Oxford

AI could predict heart attack risk up to 10 years in the future, finds Oxford study – The Guardian

  1. AI could predict heart attack risk up to 10 years in the future, finds Oxford study The Guardian
  2. American Heart Association Late-Breaking Science Presentation Reveals Majority of Adverse Cardiac Events Occur Among Patients Without Obstructive Coronary Artery Disease but Risks Are Detectable by Novel AI Yahoo Finance
  3. Artificial intelligence may speed heart attack diagnosis and treatment American Heart Association
  4. Speaking from the heart: New smartphone app predicts cardiac failure WEEKS in advance – by listening to subtle Daily Mail
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Kevin Spacey Gets Standing Ovation After Oxford University Lecture On Cancel Culture – Deadline

  1. Kevin Spacey Gets Standing Ovation After Oxford University Lecture On Cancel Culture Deadline
  2. Douglas Murray and Kevin Spacey: what Shakespeare can teach us about cancel culture | SpectatorTV The Spectator
  3. Kevin Spacey’s new movie has London premiere canceled after theater learns it’s his film Entertainment Weekly News
  4. Kevin Spacey’s film premiere axed by ‘horrified’ London cinema | Metro News Metro.co.uk
  5. Kevin Spacey bashes cancel culture in first performance since exoneration: ‘I am sick of this false world’ New York Post
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Judge denies Oxford shooter’s attempt to avoid life without parole – Detroit News

  1. Judge denies Oxford shooter’s attempt to avoid life without parole Detroit News
  2. Judge to Oxford school shooter Ethan Crumbley: Life without parole still on the table Yahoo! Voices
  3. Judge denies Oxford shooter’s request to dismiss life without parole condition Click On Detroit | Local 4 | WDIV
  4. Ethan Crumbley’s request for removing life sentence without possibility of parole denied by judge FOX 2 Detroit
  5. Judge denies Oxford shooter’s request to dismiss life without parole condition, wear street clothes WDIV ClickOnDetroit
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Should parents of Oxford shooter face charges? How judges picked apart both arguments during appeal – WDIV ClickOnDetroit

  1. Should parents of Oxford shooter face charges? How judges picked apart both arguments during appeal WDIV ClickOnDetroit
  2. Oxford High School shooter’s parents appear in court: Five takeaways USA TODAY
  3. Appeals court hears arguments in case against James & Jennifer Crumbley WXYZ-TV Detroit | Channel 7
  4. ‘You can’t sue the king.’ Qualified immunity under attack in Oxford High mass shooting lawsuit MLive.com
  5. Morning 4: Charges against Oxford shooter’s parents scrutinized by judges in appeal hearing — and other news WDIV ClickOnDetroit
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‘Goblin mode’ is Oxford University Press’ 2022 word of the year



CNN
 — 

As you read this, look around. Are you still in bed? Are there piles of clothes and takeout food boxes strewn across the floor? Do you have chip crumbs on your sheets? Have you broken your self-care routine more times than you can count? Do you not even care? If so, you might already be in “goblin mode” – chosen by the public as the 2022 Oxford word of the year.

According to Oxford University Press (OUP), publishers behind the Oxford English Dictionary, the slang term refers to a type of behavior which is “unapologetically self-indulgent, lazy, slovenly, or greedy, typically in a way that rejects social norms or expectations” – traits that may have become familiar to many during lockdown.

Social media can portray idealized versions of self-improvement, from waking at 5 a.m. and drinking a green smoothie, to keeping a journal, exercising and planning your weekly meal prep.

That era may be on the way out. In its place is goblin mode – the opposite of trying to better yourself.

The OUP word of the year – also known as the Oxford word of the year – was chosen by the public for the first time. A group of lexicographers at OUP gave people a choice of: “Goblin mode,” “metaverse,” and “#IStandWith.”

“Goblin mode” triumphed, racking up 318,956 votes – 93% of the total. “Metaverse” came second and “#IStandWith” came third.

Casper Grathwohl, president of OUP’s Oxford Languages, said in a press release Monday that the “level of engagement with the campaign caught us totally by surprise.”

“Given the year we’ve just experienced, ‘Goblin mode’ resonates with all of us who are feeling a little overwhelmed at this point. It’s a relief to acknowledge that we’re not always the idealized, curated selves that we’re encouraged to present on our Instagram and TikTok feeds,” he said.

The term was first used in 2009 but went viral on social media earlier this year, OUP said. It shot to prominence after a fake headline claimed that the rapper formerly known as Kanye West and Julia Fox broke up after she “went goblin mode.”

“The term then rose in popularity over the months following as Covid lockdown restrictions eased in many countries and people ventured out of their homes more regularly,” according to the OUP.

“Seemingly, it captured the prevailing mood of individuals who rejected the idea of returning to ‘normal life’, or rebelled against the increasingly unattainable aesthetic standards and unsustainable lifestyles exhibited on social media.”

The term’s popularity may also be linked to the growth of new social media sites like BeReal, where users are invited once a day at random to post a photo of whatever they’re doing. Goodbye carefully curated social media feeds. Hello goblin mode.

The release gives examples of examples of when the term has been used. Among the most vivid was quoted in The Guardian: “Goblin mode is like when you wake up at 2am and shuffle into the kitchen wearing nothing but a long t-shirt to make a weird snack, like melted cheese on saltines.”

“People are embracing their inner goblin, and voters choosing ‘goblin mode’ as the Word of the Year tells us the concept is likely here to stay,” added Grathwohl.

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Student accused of killing four at Oxford high school in Michigan to plead guilty

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The teenage student accused of killing four classmates in a shooting rampage at a Michigan high school last year is expected to plead guilty to two dozen charges, authorities said Friday, including terrorism — an extraordinarily unusual if not unprecedented charge in a school shooting.

Oakland County Chief Assistant Prosecutor David Williams said in a statement that Ethan Crumbley, who was 15 when he allegedly opened fire at an Oxford, Mich., school and who is being charged as an adult, is expected to plead guilty Monday to four counts of first-degree murder, seven counts of assault with intent to murder, 12 counts of possession of a firearm and one count of terrorism causing death.

“There have been no plea deals, no reductions and no sentencing agreements,” Williams said. In addition to the four killed, seven were wounded in the shooting.

The terrorism charge was designed to address the harm caused to those who suffered from the violent rampage but who were not killed or injured, Oakland County Prosecutor Karen McDonald told The Washington Post in December 2021.

Michigan’s 2002 anti-terrorism act defines terrorism as an act that is “intended to intimidate or coerce a civilian population or influence or affect the conduct of government or a unit of government through intimidation or coercion.”

An attorney for Crumbley did not immediately respond to The Washington Post’s request for comment.

In another rare move, the alleged shooter’s parents were charged with four counts of involuntary manslaughter. James and Jennifer Crumbley face allegations that they ignored warning signs in their son’s behavior and did not secure the gun their son used, which investigators alleged was stored in an unlocked drawer of their bedroom. They pleaded not guilty in 2021 and filed a motion in July to have the case against them thrown out, arguing that they never should have been charged because their son is the sole person responsible for killing four people.

In January, Ethan Crumbley’s attorneys said they would pursue an insanity defense, according to a notice they filed obtained by The Associated Press.

At the time of the shooting in November 2021, it appeared to be the deadliest episode of on-campus violence in the United States in more than 18 months.

Timothy Bella, Kim Bellware, Meryl Kornfield and Annabelle Timsit contributed to this report.

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Oxford scientists hail dementia breakthrough

Oxford scientists hail major breakthrough which could provide relief to 900,000 Britons with dementia

  • Researchers at Neuro-Bio based in Oxford have made a significant discovery 
  • They have investigated a part of the brain which had previously been ignored
  • The scientists have identified a ‘neurotoxic’ chemical which triggers dementia 
  • Having identified the chemical the scientists developed a way of neutralising it 

British scientists believe they may have discovered the first effective treatment for dementia.

Researchers at Neuro-Bio, a biotech firm spun out of the University of Oxford, say their potential remedy is likely to succeed where other treatments have failed because it tackles changes in the brain that have previously been ignored.

The scientists say they have identified a ‘neurotoxic’ chemical which triggers the early stages of the degenerative condition, and have developed a treatment that can neutralise it.

On Tuesday, Neuro-Bio will announce results of initial trials of the treatment involving mice, which show it to be effective. Baroness Susan Greenfield, one of the scientists behind the research, says the findings will herald a paradigm shift in treating the condition.

Scientists in Oxford have identified a ‘neurotoxin’ which triggers the degenerative process that leads to dementia. Having discovered the chemical, they have developed a method of neutralising its effects

Almost 900,000 people suffer from dementia in the UK – a number projected to rise to 1.6 million by 2040. Nearly 70,000 Britons die from the disease every year

Almost 900,000 people suffer from dementia in the UK – a number projected to rise to 1.6 million by 2040. Nearly 70,000 Britons die from the disease every year.

Doctors are still not sure what causes the condition, and there is currently no effective treatment to slow its progress.

Neuro-Bio’s drug is a departure from the techniques used by pharmaceutical companies for dementia therapies that typically focus on one characteristic of the disease, amyloid plaques – protein deposits that build up in the brain, affecting memory and cognitive function. But recent studies have failed to show that patients’ symptoms improved after taking drugs that destroy the plaques.

Baroness Greenfield says: ‘The majority of scientists have long believed that amyloid plaques are the cause of the disease. But we believe amyloid plaques build up well after the brain degeneration has begun.

‘That is why these treatments fail – by the time you’re seeing plaques, the horse has bolted.’

Neuro-Bio’s treatment, given as a nasal spray, focuses on cells at the centre of the brain, the isodendritic core. Studies have shown that these cells are the first to begin dying in the brain of someone with Alzheimer’s disease – the most common cause of dementia – often ten to 15 years before they experience symptoms.

‘When these cells die, it sets off a snowball effect, which cause more and more cells to die too,’ says Baroness Greenfield.

While scientists are still unsure why this process begins, Neuro-Bio claims it has found a molecule responsible for causing the damage, called T14.

Their drug, designed to limit the cell damage caused by T14, is likely to undergo human trials next.

Robert Howard, Professor of Old Age Psychiatry at University College London, says: ‘Until we know a drug is safe and effective in humans, it’s too early to get excited. But it’s true the amyloid drugs have not had the positive effect the Alzheimer’s community hoped they would.’

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“A Genealogy for All of Humanity” – University of Oxford Researchers Create Largest Ever Human Family Tree

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Lawsuit alleges Oxford High School shooter brought ammunition to school the day before shooting

“The horror of November 30, 2021 was entirely preventable,” the lawsuit said.

The complaint was initially filed in a US District Court in Michigan in December by the family of two sisters who survived the shooting, and was amended January 7. Oxford Community School District, its superintendent, the Oxford High School’s principal and dean of students, as well as unnamed counselors, teachers and a staffer are defendants.

One of the sisters was shot in the neck during the attack, the lawsuit says, and the other was narrowly missed.

The lawsuit seeks more than $100 million for each of the girls, citing the need for medical and emotional treatment.

In a statement to CNN on Wednesday, Tim Mullins, an attorney representing the Oxford Community School District, said the district and all its personnel have fully cooperated with the investigation into the shooting.

“In pursuing the investigation, prosecutors have asked and the school district certainly agrees, and we have made the commitment not to do or say anything that would confuse, interfere with or in effect obstruct their pursuit of justice on behalf of the victims of these criminal acts,” Mullins said. “The school district is honoring that commitment.”

Crumbley, 15, has been charged as an adult in the shooting. He faces one count of terrorism causing death, four counts of first-degree murder, seven counts of assault with intent to murder and 12 counts of possession of a firearm during the commission of a felony. A not-guilty plea was entered on his behalf.
Ethan Crumbley’s parents, Jennifer and James Crumbley, were arrested days after the shooting and charged with four counts each of involuntary manslaughter. They have pleaded not guilty. Prosecutors said in a filing in December that the teen’s parents were “in a better position than anyone else in the world to prevent this tragedy, but they failed to do so.”

Attorneys for Ethan, Jennifer and James Crumbley have not responded to CNN’s request for comment.

Lawsuit says alarming behavior began weeks before shooting

Ethan Crumbley displayed alarming behavior on November 11 when he brought a severed bird head to school in a mason jar filled with yellow liquid, the lawsuit said. He left the jar on a toilet paper dispenser in the boys’ bathroom, it said.

Students reported the incident to the Oxford High School principal and other school administration officials, the lawsuit said.

The next day, according to the lawsuit, the high school sent an email to parents saying: “Please know that we have reviewed every concern shared with us and investigated all information provided…[w]e want our parents and students to know that there has been no threat to our building nor our students.”

On November 16, multiple parents expressed concerns with the principal about threats Crumbley made on social media, according to the complaint. The principal and Oxford superintendent reviewed Crumbley’s posts, which threatened Oxford High students, the complaint said. Crumbley’s Instagram and other social media accounts were set to public, meaning anyone could view them, it said.

The complaint alleges that one parent told school officials, “I know it’s been investigated but my kid doesn’t feel safe at school.”

That same day, the principal emailed parents saying: “I know I’m being redundant here, but there is absolutely no threat at the HS…large assumptions were made from a few social media posts, then the assumptions evolved into exaggerated rumors.”

After the email exchanges, the superintendent warned students — over loudspeaker — “to stop spreading information over social media and stop relying on information on social media,” the lawsuit states.

“At all times relevant (the superintendent’s) actions, by advising each and every student … that there was no credible threat, demonstrated conduct so reckless as to demonstrate a substantial lack of concern for whether an injury (wound) result,” the lawsuit said.

Ethan Crumbley brought live ammunition to school, the lawsuit states

Oakland County Prosecutor Karen McDonald said last month that James Crumbley purchased the gun used in the shooting four days prior to the deadly attack.

Ethan Crumbley “had total access to this weapon,” and the parents “didn’t secure (the gun) and they allowed him free access to it,” McDonald said during the parents’ December 4 arraignment.

On November 29 — the day before the shooting — the lawsuit states Crumbley “brought live ammunition to Oxford High School and openly displayed the same while in the classroom.” That same day, a teacher saw Crumbley “searching for ammunition on his cell phone during class,” the lawsuit states. The teacher reported the incident to a counselor.

The lawsuit said officials also repeatedly failed to notify the school safety liaison officer about incidents involving Crumbley.

School officials contacted the parents via phone and email, but they did not respond. Officials “released Ethan Crumbley from school without discipline and without investigating his inappropriate internet search,” the lawsuit alleges.

Later, Jennifer Crumbley sent her son a text message saying, “LOL I’m not mad at you. You have to learn not to get caught,” according to McDonald.

That night, the lawsuit alleges, Crumbley changed his Twitter bio to read, “Now I am become Death, the destroyer of worlds. See you tomorrow Oxford.”

On the day of the shooting, another teacher found a drawing on Crumbley’s desk that essentially depicted a shooting, McDonald said. It “alarmed her to the point that she took a picture of it on her cell phone,” the prosecutor said.

The picture led school officials to hold a meeting with him and his parents, the lawsuit said.

When the parents were called that day, Jennifer Crumbley asked if James Crumbley could just call in, and she was told by the school they had called him but only heard “dead air,” Prosecutor Marc Keast said in court last week at a bond reduction hearing.

Both parents ultimately showed up at the school.

After the school discussed their concern over the teen’s drawings, the parents said neither of them could take him home, Keast told the court. Jennifer Crumbley then said, “Are we done here?” which is when the school said they had 48 hours to call a therapist, according to Keast’s account.

The parents resisted the idea of taking their son out of school, McDonald said in December, and he was allowed to return to the classroom.

The shooting happened several hours later, but prosecutors say neither parent went home to check on the location of the gun.

Madisyn Baldwin, 17; Tate Myre, 16; Hana St. Juliana, 14; and Justin Shilling, 17, died in the shooting, authorities said. Six other students and one teacher were injured.

CNN’s Jason Hanna, Taylor Romine and Kelly McCleary contributed to this report.

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Oxford Covid-19 vaccine scientist says ‘we can’t vaccinate the planet every six months’

“We can’t vaccinate the planet every four to six months. It’s not sustainable or affordable,” Professor Andrew Pollard, the director of the Oxford Vaccine Group and head of the UK’s Committee on Vaccination and Immunization, told The Daily Telegraph in an interview published Tuesday.

Pollard also stressed the “need to target the vulnerable” going forward, rather than administering doses to everyone age 12 and older. More data is needed to ascertain “whether, when and how often those who are vulnerable will need additional doses,” he said.

Pollard also said he thought further evidence was needed before offering a fourth Covid-19 shot to people in the UK, which is currently rolling out third shots to healthy people 18 and older, and at-risk people 16 and older.
In a separate interview with Sky News on Tuesday, Pollard also cited the glaring unevenness of vaccine rollouts across the world.

“It’s just not — from a global perspective — affordable, sustainable or deliverable to give fourth doses to everyone on the planet every six months,” Pollard said. “And remember that, today, less than 10% of people in low-income countries have even had their first dose, so the whole idea of regular fourth doses globally is just not sensible.”

Israel has already begun its rollout of a fourth vaccine dose, offering it to all medical workers and people 60 and older as of Monday.

And in late December, German Health Minister Karl Lauterbach told public broadcaster ZDF that Germans “will need a fourth vaccination” against Covid-19.

But Pollard struck an optimistic note in his interview. The “worst is behind us” and the world “just needs to get through the winter,” he said.

“At some point, society has to open up,” he added. “When we do open, there will be a period with a bump in infections, which is why winter is probably not the best time.”

He concluded by issuing a stark warning about the dangerous consequences of vaccine misinformation, highlighting that even “unintentional” comments from politicians can wreak havoc.

“Let’s just say that comments made in mainland Europe affected people in Africa,” he said.

Meanwhile in the United States, it’s too early to be discussing a potential fourth dose of coronavirus vaccine for most people, Dr. Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases, said on December 24.

“I think it’s too premature to be talking about a fourth dose,” Fauci told Michael Wallace and Steve Scott of WCBS Newsradio 880.

“One of the things that we’re going to be following very carefully is what the durability of the protection is following the third dose of an mRNA vaccine,” Fauci said. Moderna and Pfizer/BioNTech are mRNA vaccines.

“If the protection is much more durable than the two-dose, non-boosted group, then we may go a significant period of time without requiring a fourth dose,” Fauci said. “So, I do think it’s premature — at least on the part of the United States — to be talking about a fourth dose.”

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