Tag Archives: overcome

Nintendo says it will overcome challenges of generational transition with ‘unique propositions’ | VGC – Video Games Chronicle

  1. Nintendo says it will overcome challenges of generational transition with ‘unique propositions’ | VGC Video Games Chronicle
  2. Nintendo president reiterates the importance of Nintendo Accounts My Nintendo News
  3. Nintendo President: Generational Transitions in Gaming Consoles is Never Easy – News VGChartz
  4. Nintendo talks about the importance of fun and unique experiences for dedicated hardware, commitment to Nintendo Accounts GoNintendo
  5. Nintendo president: “We are always researching and developing new hardware and software” My Nintendo News

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Jim Cramer breaks down how to overcome investing challenges in the stock market – CNBC Television

  1. Jim Cramer breaks down how to overcome investing challenges in the stock market CNBC Television
  2. Jim Cramer just predicted that an ‘economic wave’ will soon hit the US — and it will be ‘fantastic for investors.’ But is that a good sign or a bad sign for the stock market? Yahoo Finance
  3. ‘If it gets hit, we’ll buy more,’ Jim Cramer says of this cybersecurity firm CNBC
  4. PSA: Cramer Says Stay Invested – Alibaba Group Holding (NYSE:BABA), Applied Mat (NASDAQ:AMAT) Benzinga
  5. Jim Cramer Predicted an ‘Economic Wave’ Will Soon Hit the US MoneyWise
  6. View Full Coverage on Google News

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Arizona men’s basketball vs. Stanford final score: Wildcats overcome Cardinal’s 3-point shooting, Kerr Kriisa… – Arizona Desert Swarm

  1. Arizona men’s basketball vs. Stanford final score: Wildcats overcome Cardinal’s 3-point shooting, Kerr Kriisa… Arizona Desert Swarm
  2. Utah basketball: Utes’ offensive shortcomings catch up to them again Deseret News
  3. Pac-12 Tournament: Stanford vs. Arizona odds, picks and predictions USA TODAY Sportsbook Wire
  4. Arizona Wildcats men’s basketball vs. Stanford Cardinal in Pac-12 Tournament game thread Arizona Desert Swarm
  5. Runnin’ Utes fall 73-62 to Cardinal in 1st round of Pac-12 Tournament KSL.com
  6. View Full Coverage on Google News

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Snakes have a clitoris: scientists overcome ‘a massive taboo around female genitalia’ | Snakes

Female snakes have clitorises, scientists have detailed for the first time in a study of the animal’s sex organs.

The scientists say previous research had mistaken the organs as scent glands or underdeveloped versions of penises, in a study that criticised the comparatively limited research into female sex organs.

In a study published in the journal Proceedings of the Royal Society B, the researchers found that snakes have two individual clitorises – hemiclitores – separated by tissue and hidden by skin on the underside of the tail.

“Female genitalia are conspicuously overlooked in comparison to their male counterparts, limiting our understanding of sexual reproduction across vertebrate lineages,” the study’s authors wrote.

Male snakes and lizards are known to have hemipenes – a pair of penises which are everted outside the body during reproduction. In many species, hemipenes are covered in spines or hooks.

The study’s lead author and a PhD student at the University of Adelaide, Megan Folwell, said “a massive taboo around female genitalia” was a potential factor in why snake clitorises had not been described earlier. “I think it’s a combination of not knowing what to look for and not wanting to,” she said.

A dissection showing the hemiclitores of a death adder. Photograph: La Trobe University

“Trying to find it is not always the easiest thing – some are extremely tiny,” Folwell said. She first dissected the clitorises in a death adder, in which the organ forms a triangle shape “like a heart”.

“I was fortunate that the death adder had a reasonably prominent hemiclitores,” Folwell said.

The study suggests that the sex organs “have functional significance in mating” in snakes. Though more research into snake behaviour is needed, Folwell said the team theorised the hemiclitores “could provide some sort of stimulation signalling for vaginal relaxation and lubrication, which would aid the female in copulation potentially prevent damage from those big hemipene hooks and spines during mating”.

“It could also be signalling to the ovaries to ovulate and to the oviduct to potentially prepare for sperm storage,” she added.

The researchers went on to dissect 10 snakes of nine species, including the carpet python, puff adder and Mexican moccasin.

“Some of the clitorises are quite muscular and large – in say vipers – but then they’re really thin, stretched out and small in some other snakes,” said Dr Jenna Crowe-Riddell, study co-author and postdoctoral researcher in neuroecology at La Trobe University. Sizes ranged from less than a millimetre to seven millimetres.

The study found the hemiclitores are comprised of erectile tissue that likely swell with blood, as well as nerve bundles which “may be indicative of tactile sensitivity, similar to the mammalian clitoris”.

“Now that we know that this is here, we know what it looks like, we know there’s erectile tissue with nerves – we can’t help but think: why wouldn’t this be for pleasure?” Crowe-Riddel said. “I think it’s worth opening up those questions for snakes.”

The study comes after a research abstract presented in the United States earlier this year said that the human clitoris has between 9,850-1,100 nerve fibres – about 20% more than the previously widely cited number of 8,000, which reportedly came from research carried out on cows.

– with AFP

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What dangers must we overcome before we can live on Mars?

Can humans live on Mars? The answer is startlingly simple. Can humans live in Antarctica, where the temperatures regularly fall below -50ºC (-60ºF) and it’s dark for six months of the year? Can humans live below the ocean, where pressure rapidly increases with depth to crushing levels? Can humans live in space, where there’s no air at all?

As the limits of our ingenuity, our materials science and our chemistry have grown, we’ve gone from being able to tolerate only a narrow band of conditions to expanding our presence to almost every part of the globe, and now beyond it. Even the most hostile environment we’ve ever faced – the vacuum of space – has had a continuous human population for more than two decades.

So why not Mars? If we can live in Antarctica, if we can live in space, then surely it’s simply a question of logistics. If we can put enough materiel on the surface of the Red Planet, then perhaps we can survive – and even thrive – there.

But that ‘if’ is doing an awful lot of work. When we went to the Moon, the astronauts had to carry everything for their visit in their tiny, fragile landers. The Apollo missions spent between just one and three days on the surface – and it took only three days to get to the Moon itself. When a Mars-bound astronaut will spend months in space just getting to the landing spot, spending just a couple of days on the planet isn’t going to satisfy. Any mission, even the initial one, will necessarily be planned to be months-long, and that increases the complexity of the logistics enormously.

Mars is a particularly difficult planet to land on. It’s too far away from Earth to control any descent remotely – on average, a radio signal takes 12 minutes to cover the distance – so everything has to be preprogrammed in. A single error in either the computer or in its inputs will result in a new and expensive crater, of which there’ve been many. And once the command for landing has been given, there’s nothing that anyone back in Mission Control can do to intervene – the length of time it takes between that order, and a safe landing, is known as the ‘seven minutes of terror’.

The tenuous Martian atmosphere also complicates landing. It’s thick enough that any deorbiting spacecraft requires a heatshield to prevent it from burning up, but even the latest generation of vast, supersonic-rated parachutes struggles to provide significant purchase on the tenuous air on the way down. What remains of the orbit velocity has to be accounted for, or our landers will break against the frozen Martian surface.

A vast silver rocket with everything the astronauts need for their months-long stay simply isn’t practical

Various methods have been used, but the most consistently successful has been the ‘sky crane’, a disposable frame fitted with retro-rockets that burn until it’s hovering a few yards above the surface. It then winches the lander down gently, disengages its connecting cables, and then flies a safe distance away before its propellent runs out.

The skycrane portion of the Mars 2020 lander flying away from the Perseverance rover after the rover touched down. Image taken by the rover from the surface of Mars. Photo by NASA

As expected, these calculations are very finely judged. Every pound of lander – the batteries, the solar panels, the scientific experiments – needs several kilogrammes of fuel in the sky crane. And every kilogramme of fuel in the sky crane requires several more kilogrammes of fuel on the rocket that takes it to Mars orbit. We’d send bigger, better landers to Mars if we could – but rocketry is at the very limits of our capabilities, getting a rover the size of a subcompact down to the ground. This has huge implications for conducting a successful crewed mission to Mars.

While we might dream of a vast silver rocket slowly descending to the dusty red surface, containing everything that the astronauts need for their months-long stay, we have to realise that it simply isn’t practical. That rocket, and the even-larger spaceship required to get it there, is beyond our projected launch capabilities for decades, if not centuries, to come. Planning for a successful Mars mission – for a permanent presence on Mars – requires us to work smarter, and use every advantage that we can. That includes those we can find on Mars itself.

An artist’s rendering of the Mars Ice Home concept. Photo by NASA/Clouds AO/SEArch

Mars is a planet full of useful resources, and specific dangers. On the plus side, if we pick our landing site sensibly, we don’t need to take water. Water is heavy, and there’s nothing we can do to make it lighter. It takes up space, and there’s nothing we can do to make it smaller. And, even with the very best recycling facilities, the astronauts will still require a certain amount of spare water. Yet on Mars, there are many places where water, in the form of ice, is just part of the soil. Stick a shovel in the ground, and half of what gets picked up is water ice. And we can use that water for all sorts of things, not just drinking. We can use it for chemistry.

We can split it using electrolysis into its component gases. We can breathe the oxygen – which saves us from having to take tanked air. And if we recombine it with the hydrogen, we have an explosive mixture we might use as a rudimentary rocket fuel. If we go one stage further, we can scavenge the carbon from Mars’s carbon dioxide atmosphere and synthesise hydrocarbons for a better burn.

That carbon dioxide is also vital for plant growth. Add water, and a growing medium, and suddenly supplementing our freeze-dried packets of food becomes not just a possibility, but a mission goal. Humans consume a lot of calories, but we also eat with our eyes. A side salad isn’t just nutrition, but a morale booster.

Then there’s the stuff of Mars itself. We can use that as a construction material: make bricks from it, or simply heap it up and over our existing structures. And we really need to do that because life on the Martian surface isn’t straightforward.

The red dust has become a nanoparticle and is a major hazard, both to us and to our machines

Most immediately, there’s the temperature. Mars is an average of 80 million kilometres (50 million miles) further from the Sun, and its atmosphere is too thin to buffer the extremes of daily variations. Daytime temperatures in high summer can reach a balmy 21ºC (70ºF), but that same day, just before dawn, will have recorded -90ºC (-130ºF). Temperatures can fall as far as to freeze carbon dioxide out of the atmosphere. The extra insulation provided by several feet of Martian soil is going to be a welcome bonus.

Moreover, it’ll help with a long-term threat: radiation. The Sun spits out charged particles all the time, as well as high-energy light in the form of gamma and X-rays. On Earth, and to a lesser extent, on the Moon, we’re protected by Earth’s large magnetic field, which extends out into space and deflects the solar wind around us. Mars has no such magnetic field, and while conditions at the surface aren’t acutely life-threatening, every day that astronauts spend on the surface of Mars, they are accumulating radiation damage 10 to 20 times faster than they would on Earth – not counting the occasional solar flare that squeezes a decade’s worth of exposure into a single event.

Burying the astronauts’ base beneath the ground is one relatively easy solution to this radiation problem. So is building it inside a cave – volcanic areas of Mars are the sites of lava tubes that now form huge tunnels, with access through partial roof collapses.

The soil itself is toxic, rich with perchlorates. While these are a potential source of oxygen, perchlorates are water-soluble: contaminated soil cannot be used as a growing medium.

Then there is the dust. The red dust has been formed by hundreds of millions of years of continuous grinding of volcanic ash, becoming so fine that even the weak Martian winds can carry and keep it aloft for weeks at a time. The dust has become a nanoparticle – averaging 3μm (one 10,000th of an inch) – and is a major hazard, both to us and to our machines. It would be all but impossible to exclude the dust from living spaces: astronauts would carry it in from trips outside, even with assiduous measures – washing, hoovering, anti-static screens and air filtration – it would become part of the air they breathed and the food they ate. As well as the perchlorates previously mentioned, there’s other cancer-causing compounds, and the damage that fine-grained rock powder can cause specifically to lungs and eyes.

We’ve already lost one rover to the dust, which coated its solar panels. The more complex the machinery we take, the more certain we have to be of our seals and surfaces. Maintenance, together with the spare parts to back up that regime, would have to be strictly observed.

So how might we do this? We have parameters set by the number of crew we send, how long they plan to initially stay for, and what they intend to do when they get there. We have to plan to shelter, water and feed them, and then bring them home – and, if we’re intending anything other than a one-time visit, we need to keep our eye on the long game: what kind of infrastructure can we build that will be useful into the future?

Breaking down the problem into manageable bites is by far the most feasible way. What we learn from such incremental efforts – and what we have already learned – can be used to guide us as we work our way through the various elements that we need to execute a successful, and sustainable, Mars mission.

We must prioritise a safe landing without encumbering the descent with the weight of food, fuel, air and water

The first stage would be to increase our capabilities in low Earth orbit. A multi-month journey to Mars will require the largest spaceship we’ve ever built, and almost certainly something that can’t be lofted in a single launch. It’ll need to be constructed in space, using methods similar to the International Space Station. Fuel, together with everything needed to maintain life for the long journey, will need to be shipped from Earth – twice over, as it’ll be coming back. The descent craft will be a separate part of the ship, while the main portion stays in Mars orbit.

The second stage would be to send supplies ahead to the designated landing area. If we can, we should send robotic, self-erecting modules. This would ensure that there would be somewhere safe for the newly arrived astronauts to go, and enable us to prioritise a safe landing without encumbering the descent phase with the additional weight of food, fuel, air and water. And, this way, we wouldn’t have to commit astronauts to the long and arduous journey to Mars until we know there’s enough equipment in place to sustain them. If one rocket went astray – more than one is statistically likely to be lost – we’d simply send another.

https://d2e1bqvws99ptg.cloudfront.net/user_image_upload/2195/PIA24979_-_Mastcam-Z_of_Flight_13_-_Closeup.mp4
NASA’s Perseverance Mars rover captured this close-up view of the take-off and landing of the 13th flight of the Ingenuity Mars Helicopter on 4 September 2021

One of the pieces of kit we’d send ahead would be an ascent module, an empty ship capable not just of landing on Mars, but also refuelling itself from the Martian atmosphere, ready for a return to the transfer ship in orbit.

To be clear, none of this is risk-free. Famously, an alternative speech was delivered in 1969 to the US president Richard Nixon in advance of Apollo 11’s landing, covering the scenario for failure. While our careful preparation has made success more likely, there are still situations that would be all but impossible to recover from. The main cause of this is how long it would take us to react to the unforeseen.

Supply chains are one of the most underestimated and misunderstood factors underpinning a modern economy. We are very used to being able to order anything, from anywhere, and it being available in a matter of days, if not hours. Manufacturers run just-in-time stocks from their suppliers, and retailers promise almost immediate delivery. Behind those storefronts lies a fantastically complex web of communications, transport, inventory control and personnel. We notice it only when it fails.

Almost everywhere on Earth is connected. Vital medicines, microchips, engine parts, even live organs for donation, are moved seamlessly between countries and continents. But there are places where this isn’t true, and they give us a first insight as to what challenges any Martian colonist might face.

Antarctica, despite our technology, remains one of the most isolated and inhospitable places on the planet. Almost everything that is needed – barring air, and water – has to be shipped or flown in, over vast distances and not without risk. Heavy seas, thick ice, a storm, an extra-cold snap: all see food and fuel stuck on a dock or on a runway. Antarctic bases don’t run a just-in-time supply chain, because when that supply chain is inevitably interrupted, people might die. Planning for those interruptions means having to take, and store, far more than is normally needed. Those of us who aren’t preppers will baulk at the amount of groceries required to keep a single person fed for a couple of months: the wintertime population of the Amundsen-Scott base, right on the South Pole, is 50.

Food, of course, can always be rationed. Heating can be reduced to one or two heavily insulated modules. There are back-up generators, and a doctor on site, and a modern, satellite-connected communications suite. Scientists are supported by a whole team of electricians, plumbers and technicians, working around the clock to maintain the infrastructure of the base, catching problems before they become critical and providing workaround solutions through their expertise.

The risk of death – by starvation, cold, asphyxiation, accident, illness, disease – has to be accepted

None of which has stopped problems occurring. Notably, if the base doctor falls ill and requires surgery, as has happened twice, the doctor ends up operating on themselves. In both cases, medical evacuation was impossible due to poor weather conditions and the distances involved. Some permanent bases still insist that personnel have their appendix removed before arrival.

Now, imagine that happening on Mars. A fully functioning base, sited in the most favourable position, and enjoying a multiply redundant infrastructure maintained by shifts of highly motivated and trained engineers, is still in a far, far more precarious position than any Antarctic base is today. A mercy dash to air-drop urgent medical supplies in Antarctica from the South Island of New Zealand is difficult but possible: the travel time, once everything is in place, is a matter of hours. Meanwhile, if the launch window is being kind, Earth to Mars is nine months. New generations of space drives will inevitably reduce that, but nothing can be done to erase the vast distances between the two planets. At best, 56 million kilometres (c35 million miles). At worst, when Earth is one side of the Sun, and Mars the other, 400 million kilometres (c250 million miles).

Without a doubt, it would be the longest supply chain in history, at the end of which is the harshest environment we have ever encountered. Even in the Age of Sail, the journey from England to Australia was faster.

If you’re the doctor on the first Mars mission, you have to decide not what drugs and bandages and surgical equipment you’re taking, but what you’re not taking. What can you do without? Both space and weight are limited. If you’re the engineer: how are you going to choose between this critical spare part and that critical spare part? Of course, you could ask the mission planners to send one – or two – of everything. But, given all that’s gone before, how feasible is that? At some point, enough will be too much. The risk of death – by starvation, by cold, by asphyxiation, by accident, by illness, by disease – has to be accepted.

As with all pioneers, the heaviest burden will fall on those who go first. They will be the most uncomfortable, the most precarious, the most vulnerable. Those who follow afterwards will have it, if not easy, certainly easier. The infrastructure of the initial base is designed to be expanded, as long as Earth holds faith with the project. For it’s certain that Mars will be utterly dependent on Earth for decades. How, though, would a Mars colony grow towards independence? Can we see that far ahead?

Manufacturing is a key technology here: not just the usual but vital supply of spare parts, but also the chemicals required for life. Specially tailored medicines, dietary supplements and plant nutrients will provide a measure of security for colonists; 3D printers with a vast library of models can start to deal with the physical, while the biological components can be conjured by automated synthesis machines.

Another cornerstone of a more independent Mars would be the colonists themselves – and specifically their education. Necessity is often the mother of invention, but Mars would be a very harsh taskmaster. A Martian colonist would need to devote a significant portion of their time to learning. The level of technology required to sustain a working colony would be high, and the number of personnel limited by available food and air. With everyone an expert in two or three separate areas of knowledge, a tragic accident to one need not turn into a crisis for all.

The highly precarious nature of life on Mars will inevitably lead to new social mores and codes of behaviour. Far from being rugged individualists, Martians will rely on each other for their very lives in a highly interdependent way – and they’ll reflect that, both in their relationships and their laws.

Just how divergent colonists become from the mother planet remains to be seen. But an independent Mars wouldn’t be a carbon-copy of any Earth society. It would be startlingly, and profoundly, alien.

The Red Planet: A Natural History of Mars (2022) by Simon Morden is published by Pegasus Books.

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Exercises To Overcome Insulin Resistance

Diabetes: Weight training increases insulin sensitivity.

The pancreas produces the hormone insulin, which enables cells to take up and utilise glucose. Cells are unable to utilise insulin adequately in persons with insulin resistance. Glucose, often known as blood sugar, accumulates in the body when the cells are unable to absorb it. Doctors refer to this condition as prediabetes if blood sugar levels are higher than normal but not high enough to suggest diabetes.

People with significant levels of insulin resistance frequently develop prediabetes. Insulin resistance can be caused by a variety of hereditary and environmental causes. Our workout routine might also worsen or improve our insulin sensitivity. In this article, we discuss workouts and exercises that can help you overcome insulin resistance.

Exercise for diabetes: Try these workout routines to reduce insulin resistance:

1. HIIT

The most crucial factor to take into account when it comes to metabolic disorders is intensity. While HIIT should be included in your regular routine, it only requires 20 to 25 minutes of exercise 2-3 times per week to produce remarkable benefits. The HIIT technique requires repeating extensive recovery intervals between short bursts of high-intensity exercise.

It is the Type 2 muscle fibres that conduct the majority of the effort during HIIT exercises. This encourages the muscles to absorb blood glucose for use as fuel. Consequently, blood glucose levels drop. The really intriguing element is that studies have revealed that this occurs whether or not there is insulin present. Therefore, those with Type 1 diabetes can benefit from this strategy as well.

2. Walk as much as possible

Throughout the day, getting up and moving helps insulin levels. In addition to being a risk factor for ill health regardless of exercise levels, prolonged sitting is linked to decreased insulin sensitivity. In actuality, sitting or watching television is linked to a higher mortality rate and type 2 diabetes.

Walking whenever can help you combat these issues. Make a goal to walk at least 10,000 steps daily. Preferably gradually throughout the day and not just at the end of the day or in the morning. Running and jogging may be initiated as well as you can benefit from them as well.

3. Try weight training

By enhancing both insulin-dependent and insulin-independent glucose absorption, weight training increases insulin sensitivity. There must be a transporter to make it possible for glucose to flow from the bloodstream into the muscles, and insulin does this.

But muscle contractions also make this possible without the need for insulin, which is one of the fantastic things about exercise. In addition to this, lifting weights increases your lean body mass. Gaining muscle mass has many positive effects, including a faster metabolism, longer life, and improved insulin sensitivity.

4. Try sprinting

Sprinting depletes the muscles’ glycogen, or carbohydrate, reserves. It’s a very time-effective form of exercise that results in a variety of metabolic adaptations that regular endurance exercise produces. These adaptations include larger aerobic capabilities, healthier cells with enhanced immune systems, and increased insulin sensitivity. It works wonders for enhancing blood glucose response.

Make sure to also keep your diet in mind. Along with these exercises, you must also consume foods fit for diabetics.

Disclaimer: This content including advice provides generic information only. It is in no way a substitute for a qualified medical opinion. Always consult a specialist or your own doctor for more information. NDTV does not claim responsibility for this information.

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Centre vs Judiciary: How To Make Judges’ Appointments Transparent

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Raleigh shooting suspect: Parents of 15-year-old Austin Thompson are ‘overcome with grief’ after 5 people were killed



CNN
 — 

The parents of a 15-year-old accused of killing five people in North Carolina last week say they’re devastated by the loss of innocent lives.

“Words cannot begin to describe our anguish and sorrow,” Alan and Elise Thompson said in a statement through their attorneys, which was obtained by CNN affiliate WTVD.

“Our son Austin inflicted immeasurable pain on the Raleigh community, and we are overcome with grief for the innocent lives lost,” the parents said.

“We pray for the families and loved ones of Nicole Conners, Susan Karnatz, Mary Marshall, and Raleigh Police Officer Gabriel Torres. We mourn for their loss and for the loss of our son, James,” the statement continued.

“We pray that Marcille “Lynn” Gardner and Raleigh Police Officer Casey Clark fully recover from their injuries, and we pray for everyone who was traumatized by these senseless acts of violence.”

Austin Thompson remains hospitalized in critical condition. The teen has not been charged, but Wake County District Attorney Lorrin Freeman has said her office intends on charging the suspect as an adult.

Just like so many others, his parents say they don’t understand why the mass tragedy happened.

“We have so many unanswered questions,” the Thompsons’ statement said.

“There were never any indications or warning signs that Austin was capable of doing anything like this.”

The parents said they will continue cooperating with law enforcement “and do whatever we can to help them understand why and how this happened.”

According to the non-profit Gun Violence Archive, there have been at least 546 mass shootings in the US this year. That’s an average of more than 1.8 mass shootings every day.

Both the Gun Violence Archive and CNN define a mass shooting as one in which at least four people are shot, excluding the shooter.

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College football scores, rankings, highlights: Clemson, USC overcome slow starts to remain undefeated

Though Week 6 marked a rare Saturday in which no top-10 teams lost, little came easy for the nation’s best teams as upsets were thwarted by some heavy favorites around the country. Among those escaping with victories after some early trouble were No. 1 Alabama, No. 5 Clemson and No. 6 USC with all three teams remaining undefeated ahead of big conference games next week.

Clemson found itself locked in a 3-3 tie with struggling Boston College for nearly the entire second quarter before the Tigers finally scored the game’s first touchdown in the final minute of the first half en route to a 31-3 win. Though the Tigers dominated defensively, it was clear even in a 28-point victory that the offense remains a work in progress; Clemson totaled just 364 yards and punted seven times. The Tigers travel to Florida State next week.

Similarly, USC held off Washington State for a 30-14 home win largely because of its defense. The Trojans initally squandered an early 10-0 lead by allowing back-to-back touchdown drives in the second quarter. From there, they buckled down, holding Washington State scoreless on its next eight possessions to close the game. Travis Dye led the way offensively with 149 yards rushing and a touchdown on 28 carries for the Trojans, which travel to face No. 11 Utah next week. The Utes lost 42-32 at UCLA on Saturday but may still present USC with its toughest test yet.

Outside the top 10, NC State overcame the loss of quarterback Devin Leary to edge a feisty Florida State team 19-17. The Wolfpack outscored the Seminoles 16-0 in the second half with Leary on the sideline with his arm in a sling. 

College football scores, schedule: Week 6

No. 4 Michigan 31, Indiana 10 — Recap
No. 8 Tennessee 40, No. 25 LSU 13 — Takeaways, recap
No. 17 TCU 38, No. 19 Kansas 31 — Recap
No. 23 Mississippi State 40, Arkansas 17 — Recap
Texas 49, Oklahoma 0 — Takeaways, recap
No. 2 Georgia 42, Auburn 10  — Takeaways, recap
No. 7 Oklahoma State 41, Texas Tech 31 — Recap
No. 18 UCLA 42, No. 11 Utah  32 —  Recap
No. 3 Ohio State 49, Michigan State 20 — Takeaways, recap
No. 5 Clemson 31, Boston College 3 — Recap
No. 6 USC 30, Washington State 14  — Recap
Notre Dame 28, No. 16 BYU 20 —  Recap
No. 1 Alabama 24, Texas A&M 20 — Takeaways, recap
Check out the entire Week 6 scoreboard 

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Ohio State vs. Notre Dame score, takeaways: No. 2 Buckeyes battle back to overcome No. 5 Fighting Irish

No. 2 Ohio State overcame lackluster play and an injury to one of their star players while battling back and ultimately beating No. 5 Notre Dame 21-10 in an exciting season opener. The Buckeyes trailed at halftime and into the third quarter before the Ohio State offense put together its best drive of the night late in the contest as star quarterback C.J. Stroud completed 24 of 34 passes for 223 yards and two touchdowns

That 10-play, 70-yard drive that ended with a 24-yard touchdown pass from Stroud to Xavier Johnson that seemed to wake up the Buckeyes and the 100,000 in attendance at Ohio Stadium. It was the last moment they had to cheer, however, as Ohio State followed with an even better drive, going 95 yards in 14 plays to put the game out of reach.

After losing star receiver Jaxon Smith-Njigba to a leg injury in the first quarter, the Buckeyes struggled to find a rhythm on offense, but Emeka Egbuka and running backs TreVeyon Henderson and Miyan Williams stepped up to fill the void.

The Fighting Irish offense got off to a promising start, picking up 54 yards on the first play of the night, but it managed only 199 yards for the rest of the game. Tyler Buchner (177 yards passing, 18 rushing) made some plays, but Notre Dame could never find consistency against an Ohio State defense that played with its hair on fire.

Tommy Eichenberg finished with two sacks for Ohio State, while Mike Hall had another sack and two tackles for loss. With their second-half comeback, the Buckeyes were able to avoid becoming the first top two team to lose its season opener since No. 1 Miami fell to BYU to begin the 1990 season.

Let’s take a look at the key takeaways from Ohio State’s big Week 1 win over Notre Dame.

Ohio State’s defense won the game

There were questions about how Ohio State would perform in Jim Knowles’ first game as defensive coordinator. Early returns are quite promising. While the Buckeyes ended up winning somewhat comfortably, it’s only because their defense picked up a lackluster offense time and again. While Notre Dame hit the occasional big play through the air, the Buckeyes did not allow the Irish to string together significant drives. It looked like a completely different unit than the one that too often allowed teams to move the ball down the field in crucial spots last season.

The most significant difference was the pressure. Knowles threw all sorts of disguises at the inexperienced Buchner. All of it — blitzes, stunts, and pass-rushers like Zach Harrison dropping into coverage — was designed to keep Buchner guessing and unsure of where to go with the ball; it worked, for the most part. The Buckeyes finished with six tackles for loss and three sacks as they held Notre Dame to 5.3 yards per play. More importantly, it allowed the Irish to convert only 3 of 13 third downs while forcing them into third-and-long situations all night. That kept the Irish from being able to sustain drives, and it bought the Buckeyes offense more time to figure things out.

Ohio State’s wide receiver depth is an issue

Who would’ve thought we’d be saying that?! Ohio State’s receiver corps is supposed to be the best in the country, but Smith-Njigba suffered an undisclosed leg injury on the team’s first series and saw only a few more plays the rest of the night. Julian Fleming was already banged up. That meant the Buckeyes had to play with a lot of inexperienced receivers, and it showed. There was miscommunication about where they were supposed to be on routes and the timing was off with Stroud.

Still, things picked up in the second half with Egbuka emerging as the most reliable target. Egbuka finished with nine receptions for 90 yards and a touchdown. Marvin Harrison Jr. caught five passes for 56 yards, and while Johnson caught only two passes, his 24-yard touchdown proved the game-winner. In the end, six receivers aside from Smith-Njigba (two catches, 3 yards) caught passes from Stroud on the evening.

Notre Dame must find a run game

Coming into the evening, I thought Notre Dame’s problem on offense would be a lack of explosive plays in the passing game, making it difficult to keep up with the high-powered Ohio State offense. While they weren’t consistent enough throughout the night, Buchner and his receivers hooked up for four passes of at least 20 yards, including a 54-yard connection with Lorenzo Styles on the first play of the game. The problem was the Irish couldn’t do anything on the ground. The Ohio State defense held Notre Dame to only 76 yards rushing on 30 carries. Adjust for sacks, and that number only improves to 95 yards on 27 carries (3.5 per touch).

With a young quarterback making his first start on the road in a demanding environment, the Irish would have ideally gotten more from their ground game to take the load off Buchner. Instead, Buchner had to carry the load, and it went about as well as you’d expect in the long run.

Stroud can — and must — do better

Frankly, Stroud looked ordinary in the first half and shaky to start the second half. It wasn’t until the middle of the third quarter that he seemed to find a rhythm, and from that point onward, Ohio State took control of the game. Stroud’s final stat line isn’t going to turn many heads (not for the right reasons, anyway), but he made big throws late when he had to and helped his team pick up a crucial win.

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Nonsurgical Implant Could Help Overcome Obesity by Killing Cells Producing Ghrelin, the “Hunger Hormone”

In this illustration, an implant (blue and gray) creates a feeling of fullness by pressing on the stomach and, when activated by a laser (black), killing cells that produce the hunger hormone. Credit: Adapted from ACS Applied Materials & Interfaces 2022, DOI: 10.1021/acsami.2c00532

When dieting and exercise aren’t enough, weight-loss surgery can be an effective obesity treatment. But people who don’t want surgery have other options, including insertion of an appetite-suppressing balloon or other implant in the stomach. Now, researchers report in ACS Applied Materials & Interfaces that they have augmented that procedure in laboratory animals by coating an implant with a laser-activated dye that kills cells producing ghrelin, the “hunger hormone.”

Implants can be inserted in the stomach through the mouth after local anesthesia. In 2019, Hwoon-Yong Jung, Jung-Hoon Park and colleagues designed a new type of implant. The “intragastric satiety-inducing device” (ISD) consists of a stent — which lodges in the lower esophagus — attached to a disk that rests in the opening to the stomach. The disk has a hole in the center to let food through. Tests in pigs showed that the ISD lowered food intake and weight gain by enhancing the feeling of fullness and reducing levels of ghrelin, which is produced by cells near the top of stomach. But the device caused complications, including

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