Tag Archives: Innovation

FACT SHEET: One Year after the CHIPS and Science Act, Biden-Harris Administration Marks Historic Progress in Bringing Semiconductor Supply Chains Home, Supporting Innovation, and Protecting National Security – The White House

  1. FACT SHEET: One Year after the CHIPS and Science Act, Biden-Harris Administration Marks Historic Progress in Bringing Semiconductor Supply Chains Home, Supporting Innovation, and Protecting National Security The White House
  2. Semiconductor makers wait for checks one year after Biden signs CHIPS Act CNBC
  3. Biden touts economic agenda on first anniversary of CHIPs and Science Act AOL
  4. US reports big interest in $52 billion semiconductor chips funding Reuters
  5. Biden Touts $166B in Planned Semiconductor Plant Projects Since CHIPS Act Engineering News-Record
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Generative AI: A new Gold Rush for software engineering innovation – VentureBeat

  1. Generative AI: A new Gold Rush for software engineering innovation VentureBeat
  2. A New AI Research Introduces MONAI Generative Models: An Open-Source Platform that Allows Researchers and Developers to Easily Train, Evaluate, and Deploy Generative Models MarkTechPost
  3. Don’t quit your day job: Generative AI and the end of programming VentureBeat
  4. Harnessing the potential of Generative AI – A journey from experimentation to adoption Times of India
  5. Beyond imagination: India’s quest to harness generative AI Times of India
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Revolutionary Ripple: Central Banks Embrace Innovation, Test 30+ CBDC Use Cases, including Offline Payments – Is XRP at the Forefront? – Crypto News Flash

  1. Revolutionary Ripple: Central Banks Embrace Innovation, Test 30+ CBDC Use Cases, including Offline Payments – Is XRP at the Forefront? Crypto News Flash
  2. ‘Britcoin’ launch inches closer after Project Rosalind CBDC tests Cointelegraph
  3. Bank of England Completes Retail CBDC Study BeInCrypto
  4. Ripple: Central Banks Explore CBDC Potential with Successful Testing of 30+ Use Cases, Including Offline Payments – Is XRP the Ideal Base Layer? Report Crypto News Flash
  5. Quant Collaborates With Bank for International Settlements and Bank of England on Project Rosalind as Technology Vendor Yahoo Finance

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Intel To Host Innovation 2023 Event on 19th September: Meteor Lake, Raptor Lake Refresh & Alchemist+ Expected – Wccftech

  1. Intel To Host Innovation 2023 Event on 19th September: Meteor Lake, Raptor Lake Refresh & Alchemist+ Expected Wccftech
  2. Efficient Intel Meteor Lake described as “Zen 4 Phoenix Killer” as leak claims Intel is working on a 40-core Arrow Lake CPU Notebookcheck.net
  3. Intel Innovation 2023 set for September 19, Raptor Lake Refresh launch? VideoCardz.com
  4. Intel’s Innovation 2023 conference revealed for September 19-20 Neowin
  5. Intel Panther Lake and Beast Lake leak suggests up to 40% more single-core performance vs Arrow Lake for former and Extra Big cores for latter Notebookcheck.net
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Intel Innovation 2023 set for September 19, Raptor Lake Refresh launch? – VideoCardz.com

  1. Intel Innovation 2023 set for September 19, Raptor Lake Refresh launch? VideoCardz.com
  2. Efficient Intel Meteor Lake described as “Zen 4 Phoenix Killer” as leak claims Intel is working on a 40-core Arrow Lake CPU Notebookcheck.net
  3. Intel Beast Lake: 10 performance cores and huge clocks to beat AMD’s X3D CPUs? TweakTown
  4. Intel’s Innovation 2023 conference revealed for September 19-20 Neowin
  5. Intel Panther Lake and Beast Lake leak suggests up to 40% more single-core performance vs Arrow Lake for former and Extra Big cores for latter Notebookcheck.net
  6. View Full Coverage on Google News

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Sony: Microsoft’s Call of Duty ‘Offer Will Irreparably Harm Competition and Innovation’ – News – VGChartz

  1. Sony: Microsoft’s Call of Duty ‘Offer Will Irreparably Harm Competition and Innovation’ – News VGChartz
  2. Sony: Xbox’s Call of Duty Offer Will ‘Irreparably Harm Competition’ IGN
  3. Microsoft’s Current Offer To Sony For Call Of Duty “Will Irreparably Harm Competition And Innovation In The Industry,” Says Sony PlayStation Universe
  4. Microsoft Redacted Info on Call of Duty Offer to PlayStation, Sony Says PlayStation LifeStyle
  5. Sony Says Xbox’s Call of Duty Offer Would ‘Irreparably Harm Competition’ GameRant
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Fifth Ramnath Goenka Lecture: India can be innovation hub for world, says Bill Gates – The Indian Express

  1. Fifth Ramnath Goenka Lecture: India can be innovation hub for world, says Bill Gates The Indian Express
  2. The Internet is obsessed with this million-dollar pic of Bill Gates and Ratan Tata. See post India Today
  3. World counting on India to play central role in tackling climate crisis, says Bill Gates The Independent
  4. Bill Gates appreciated India’s Covid management, vaccination drive, digital health initiatives: Mandaviya Times of India
  5. YouTuber Prajakta Koli meets Bill Gates during his India visit. See what she posted India Today
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Alcohol Flushing Response May Increase Chances of Heart Disease

If you’re East or Southeast Asian, you’re probably very familiar with the alcohol flushing response—otherwise known as the “Asian glow.” After one or two drinks, your face and body grows redder than a sun-dried tomato, and people start asking you if you somehow got sunburned at the bar or party that night.

The flushing response is the result of a genetic quirk. More specifically, it’s an inherited deficiency with an enzyme dubbed aldehyde deydrogenase 2 (ALDH2). This genetic variant itself is called ALDH2*2 and affects roughly 8 percent of the world population.

While the glow is often just an embarrassing thing that can happen during a night out, more and more researchers are discovering that it can actually have some life-threatening effects on the human body. Stanford scientists published a paper on Jan. 25 in the journal Science Translation Medicine that found that those with the flushing gene variant might have a higher risk of heart disease. The findings suggest that those with the variant might want to reconsider their drinking habits.

Specifically, the variant causes blood vessel inflammation in response to alcohol consumption. This limits the flow of blood throughout the body, and could lead to coronary artery disease.

“We found mice carrying this variant have impaired vascular dilatation,” Joseph Wu, director of the Stanford Cardiovascular Institute and co-author of the study, told The Daily Beast in an email. “When treated with alcohol, mice with this variant demonstrated enlarged vascular size, increased vascular thickness, and impaired vascular contraction and relaxation.”

The authors discovered that people who participated in the new study and had ALDH2*2 suffered from impaired vascular function—even after just modest alcohol consumption or “one standard drink,” Wu said. This means that any amount of alcohol is potentially dangerous to those with the variant—especially if you already have exacerbating factors such as a family history with heart disease, high blood pressure, or high cholesterol.

However, there was a glimmer of hope. The researchers discovered that a diabetes drug dubbed empagliflozin seemed to have a nullifying effect on the symptoms in cultured human cells. It also improved blood vessel function in mice. The drug might be able to help humans at risk of heart disease due to the variant.

But Wu cautioned that the drug doesn’t “directly stimulate ALDH2 activity”—meaning it doesn’t target the flush response. Therefore, it won’t lessen your glow if you have it. “However, our studies showed that empagliflozin may potentially be used as a preventative measure against vascular diseases, especially in high-risk patient cohort such as ALDH2*2 carriers who drink excessively,” he explained.

This just adds to the body of evidence that drinking is actually horrible for people with the alcohol flushing variant. Not only have studies shown that it can damage your DNA, but it also increases your risk of cancer. Drinking is also just terrible for you in general—but especially if you have the glow.

So, in the meantime, it’s important to remember that line from all those beer commercials and drink responsibly—especially if you glow red as a beet when you knock back a few. Heck, it’s probably a better idea to cut it out entirely. Of course, that’s a lot easier said than done.

“We realize it is very difficult for people to abstain from alcohol completely for a variety of reasons,” Wu said. “Hence we encourage people with this variant to be cognizant of the strong scientific findings that point to the harmful effects of alcohol and to cut down on alcohol consumption as much as possible.”

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New COVID Variants Are Escaping the Immune System. Here’s What That Means.

BA.5, BQ.1.1, and XBB? It’s no wonder people are struggling to keep all the circulating variants of COVID-19 straight right now. Whether you want to call them “alphabet soup,” “Scrabble,” or “Kraken,” we’ve been reminded time and again that it’s not the name of the subvariant that matters, but rather the way it interacts with our immune systems. And as we enter into our fourth year with COVID-19, scientists are most concerned with how well prior infections, vaccinations, and boosters can protect us against emerging variants of the virus.

The answers are starting to roll in—and they’re not looking great for us. In a letter published on Jan. 18 in The New England Journal of Medicine, researchers from Beth Israel Deaconess Medical Center and Los Alamos National Laboratory detail the nasty abilities of variants BQ.1.1 and XBB.1 to escape incapacitation from COVID-specific antibodies. This is cause for concern because as the authors wrote, these variants “may reduce the efficacy of current mRNA vaccines.”

Before Aug. 31 in the U.S., available COVID-19 boosters were monovalent, meaning they contained viral genetic material from one strain of the virus. The updated boosters are bivalent and were created with genetic material from the original COVID-19 strain as well as Omicron variant strains with the hope of offering better protection against new and emerging variants.

Unfortunately, these early data seem to show that two of the newest variants can dodge even the bivalent boosters. In their study, the researchers took serum samples from 16 people who received a monovalent booster in 2021, 15 who received a monovalent booster in 2022, and 18 people who received a bivalent booster in September 2022. In all three cohorts, the concentration of neutralizing antibodies—which immobilize copies of the virus and prevent them from infecting cells—fighting the original Wuhan strain shot up after participants received boosters, from the hundreds or thousands to the tens of thousands.

But their immune response against some of the newest viral variants was severely diminished, even compared to ones that came directly before. The authors found that neutralizing antibody concentrations to variants BQ.1.1 and XBB.1 were between 53 and 232 times lower than those to the original strain of COVID-19, depending on the booster received. These variants were even better than a recent Omicron variant at evading the immune system and escaping neutralizing antibodies.

On Jan. 11, the World Health Organization released a risk assessment about XBB.1.5, writing that BQ and XBB variants are “the most antibody-resistant variants to date” but cautioning that “[t]here is currently no data on real world vaccine effectiveness against severe disease or death” for these variants.

It’s clear that these variants aren’t good news, but future research is needed to suss out just how bad they will turn out to be. This study is one early indication that as sick as we might be of the COVID-19 pandemic, we aren’t out of the woods just yet.

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How Ukraine became a laboratory for western weapons and battlefield innovation



CNN
 — 

Last fall, as Ukraine won back large swaths of territory in a series of counterattacks, it pounded Russian forces with American-made artillery and rockets. Guiding some of that artillery was a homemade targeting system that Ukraine developed on the battlefield.

A piece of Ukrainian-made software has turned readily available tablet computers and smartphones into sophisticated targeting tools that are now used widely across the Ukrainian military.

The result is a mobile app that feeds satellite and other intelligence imagery into a real-time targeting algorithm that helps units near the front direct fire onto specific targets. And because it’s an app, not a piece of hardware, it’s easy to quickly update and upgrade, and available to a wide range of personnel.

US officials familiar with the tool say it has been highly effective at directing Ukrainian artillery fire onto Russian targets.

The targeting app is among dozens of examples of battlefield innovations that Ukraine has come up with over nearly a year of war, often finding cheap fixes to expensive problems.

Small, plastic drones, buzzing quietly overhead, drop grenades and other ordinance on Russian troops. 3D printers now make spare parts so soldiers can repair heavy equipment in the field. Technicians have converted ordinary pickup trucks into mobile missile launchers. Engineers have figured out how to strap sophisticated US missiles onto older Soviet fighter jets such as the MiG-29, helping keep the Ukrainian air force flying after nine months of war.

Ukraine has even developed its own anti-ship weapon, the Neptune, based off Soviet rocket designs that can target the Russian fleet from almost 200 miles away.

This kind of Ukrainian ingenuity has impressed US officials, who have praised Kyiv’s ability to “MacGyver” solutions to its battlefield needs that fill in important tactical gaps left by the larger, more sophisticated Western weaponry.

While US and other Western officials don’t always have perfect insight into exactly how Ukraine’s custom-made systems work – in large part because they are not on the ground – both officials and open-source analysts say Ukraine has become a veritable battle lab for cheap but effective solutions.

“Their innovation is just incredibly impressive,” said Seth Jones, director of the international security program at the Center for Strategic and International Studies.

Meanwhile, the war in Ukraine has also offered the United States and its allies a rare opportunity to study how their own weapons systems perform under intense use – and what munitions both sides are using to score wins in this hotly fought modern war. US operations officers and other military officials have also tracked how successfully Russia has used cheap, expendable drones that explode on impact, provided by Iran, to decimate the Ukrainian power grid.

Ukraine is “absolutely a weapons lab in every sense because none of this equipment has ever actually been used in a war between two industrially developed nations,” said one source familiar with Western intelligence. “This is real-world battle testing.”

For the US military, the war in Ukraine has been an incredible source of data on the utility of its own systems.

Some high-profile systems given to the Ukrainians – such as the Switchblade 300 drone and a missile designed to target enemy radar systems – have turned out to be less effective on the battlefield than anticipated, according to a US military operations officer with knowledge of the battlefield, as well as a recent British think tank study.

But the lightweight American-made M142 multiple rocket launcher, or HIMARS, has been critical to Ukraine’s success – even as officials have learned valuable lessons about the rate of maintenance repair those systems have required under such heavy use.

How Ukraine has used its limited supply of HIMARS missiles to wreak havoc on Russian command and control, striking command posts, headquarters and supply depots, has been eye-opening, a defense official said, adding that military leaders would be studying this for years.

Another crucial piece of insight has been about the M777 howitzer, the powerful artillery that has been a critical part of Ukraine’s battlefield power. But the barrels of the howitzers lose their rifling if too many shells are fired in a short time frame, another defense official said, making the artillery less accurate and less effective.

The Ukrainians have also made tactical innovations that have impressed Western officials. During the early weeks of the war, Ukrainian commanders adapted their operations to employ small teams of dismounted infantry during the Russian advance on Kyiv. Armed with shoulder-mounted Stinger and Javelin rockets, Ukrainian troops were able to sneak up on Russian tanks without infantry on their flanks.

The US has also closely studied the conflict for larger lessons on how a war between two modern nations might be waged in the 21st century.

The operations officer said that one lesson the US may take from this conflict is that towed artillery – like the M777 howitzer system – may be a thing of the past. Those systems are harder to move quickly to avoid return fire – and in a world of ubiquitous drones and overhead surveillance, “it’s very hard to hide nowadays,” this person said.

When it comes to lessons learned, “there’s a book to be written about this,” said Democratic Rep. Jim Himes of Connecticut, a member of the House Intelligence Committee.

US defense contractors have also taken note of the novel opportunity to study – and market – their systems.

BAE Systems has already announced that the Russian success with their kamikaze drones has influenced how it is designing a new armored fighting vehicle for the Army, adding more armor to protect soldiers from attacks from above.

And different parts of the US government and industry have sought to test novel systems and solutions in a fight for which Ukraine needed all the help it could get.

In the early days of the conflict, the National Geospatial-Intelligence Agency sent five lightweight, high-resolution surveillance drones to US Special Operations Command in Europe – just in case they might come in handy in Ukraine. The drones, made by a company called Hexagon, weren’t part of a so-called program of record at the Defense Department, hinting at the experimental nature of the conflict.

Navy Vice Adm. Robert Sharp, the head of the National Geospatial-Intelligence Agency at the time, even boasted publicly that the US had trained a “military partner” in Europe on the system.

“What this allows you to do is to go out underneath cloud cover and collect your own [geointelligence] data,” Sharp told CNN on the sidelines of a satellite conference in Denver last spring.

Despite intense effort by a small group of US officials and outside industry, it remains unclear whether these drones ever made it into the fight.

Meanwhile, multiple intelligence and military officials told CNN they hoped that creating what the US military terms “attritable” drones – cheap, single-use weapons – has become a top priority for defense contractors.

“I wish we could make a $10,000 one-way attack drone,” one of these officials said, wistfully.

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