- Just 1 Dose of New Antibiotic Class Eliminates Resistant Blood Infections in Mice ScienceAlert
- Macrocyclic peptides: up-and-coming weapons to combat antimicrobial resistance | Signal Transduction and Targeted Therapy Nature.com
- Fluorous lipopeptides act as highly effective antibiotics for multidrug-resistant pathogens Phys.org
- New research to starve resistant bacteria • healthcare-in-europe.com healthcare-in-europe.com
- Antibiotic Hits Novel Target, a Lipid Enzyme, Defeats Resistant Bacteria in Mice Genetic Engineering & Biotechnology News
Tag Archives: Eliminates
Female-led IDF combat squad eliminates nearly 100 Hamas terrorists in firefights along border, report says – Fox News
- Female-led IDF combat squad eliminates nearly 100 Hamas terrorists in firefights along border, report says Fox News
- Israeli commander says unit of mostly women killed 100 Hamas militants Business Insider
- Israel-Hamas war live updates: New footage shows IDF soldiers ‘neutralize’ Hamas terrorists and rescuing residents at kibbutz where over 100 were slaughtered New York Post
- In “Never-Before-Seen” Video, Israel Destroys Hamas Cell, Saves Hostages NDTV
- IDF publishes footage of troops battling Hamas terrorists in Be’eri The Times of Israel
- View Full Coverage on Google News
Herd That eliminates Boeheim’s Army from TBT with dominating offensive show (Donna Ditota’s quick hits) – syracuse.com
- Herd That eliminates Boeheim’s Army from TBT with dominating offensive show (Donna Ditota’s quick hits) syracuse.com
- Former Tar Heel JP Tokoto delivers game-winner for Herd That Tar Heels Wire
- Boeheim’s Army knocked out of TBT by Herd That, 88-71: Final score, recap syracuse.com
- Boeheim’s Army collapses in the 2nd half versus Herd Team in TBT Elite Eight Troy Nunes Is An Absolute Magician
- Gamethread: Boeheim’s Army vs Herd That in TBT Elite Eight matchup Troy Nunes Is An Absolute Magician
- View Full Coverage on Google News
‘Dancing With the Stars’ Eliminates First Celeb During Season Premiere on Disney+
“Dancing with the Stars” made the move to Disney+ on Monday night, streaming live coast-to-coast, and the initial installment wrapped up with an elimination.
(Spoiler alert: This story reveals who went home on “DWTS.”)
At the end of the two-hour Season 31 premiere, which allowed voting throughout the night via text, two couples were left in the bottom 2 — “Real Housewives of New Jersey” star Teresa Giudice and pro Pasha Pashkov, and “Sex and the City” alum Jason Lewis and pro Peta Murgatroyd. And the eliminated couple ended up being Lewis and Murgatroyd.
“I am so sad that I have to go home. It was amazing,” Lewis said, noting everyone was so supportive among the cast during his brief stint on the show.
While Giudice and Lewis landed near the bottom of the leaderboard on Monday night with their pros, “Jersey Shore’s” Vinny Guadagnino and pro Koko Iwasaki were actually in the lowest spot. They were, however, saved by the viewer text messages to go through to the following week — Elvis week.
Also Read:
‘Dancing With the Stars’ Career Bump: 13 Contestants Who Got the Biggest Boost (Photos)
The premiere of the now-live streaming show went off with almost no issues. At one point, host Tyra Banks announced the wrong couple at the top of the leaderboard, but she noted she was given wrong information and quickly corrected it.
“Dancing With the Stars” overall felt familiar, despite being on streaming, with the show moving quickly throughout the night. Instead of commercials, in between competition dances, the pro troupe would come out and perform versions of the dances the celebrities had to do.
“Let’s Make a Deal” host Wayne Brady came out as an early frontrunner of the evening, scoring 29 out of 40 for his cha cha with pro partner Witney Carson.
“Welcome to Wayne’s dance floor. Performance level through the roof,” judge Bruno Tonioli said after Brady and Carson combined some Michael Jackson-style moves with the cha cha. “You’ve got it and you know what to do with it.”
Carrie Ann Inaba told Brady he was “fabulous,” while head judge Len Goodman called their routine “the most watchable dance of the night so far.”
But there was more to come. “RuPaul’s Drag Race” alum and “We’re Here” star Shangela hit the dance floor with Gleb Savchenko for a sassy salsa that left fourth judge Derek Hough impressed.
“You were so fantastic. You have so much energy,” he said.
Also Read:
What Time Does ‘Dancing With the Stars’ Stream on Disney+?
Selma Blair, who has multiple sclerosis, danced with Sasha Farber, who she said is her neighbor. The pair did a Viennese waltz that left others in the ballroom, including competitor Jordin Sparks and pro Pasha Pashkov, in tears.
“You really created magic tonight. It was gorgeous,” Tonioli said.
But Charli D’Amelio, the TikTok star, who went last for a cha cha with returning pro Mark Ballas, topped the leaderboard.
“This performance is really the cherry on the cake,” Tonioli said.
Leaderboard:
Charli D’Amelio & Mark Ballas – cha cha – 32/40
Wayne Brady & Witney Carson – cha cha – 29/40
Shangela & Gleb Savchenko – salsa – 28/40
Gabbey Windy & Val Chmerkovskiy – jive – 28/40
Selma Blair & Sasha Farber – Viennese waltz – 28/40
Daniel Durant & Britt Stewart – fox trot – 27/40
Jordin Sparks & Brandon Armstrong – cha cha – 26/40
Heidi D’Amelio & Artem Chigvintsev – cha cha – 24/40
Joseph Baena & Daniella Karagach – jive – 23/40
Cheryl Ladd & Louis Van Amstel – cha cha – 21/40
Trevor Donovan & Emma Slater – quickstep – 21/40
Sam Champion and Cheryl Burke – fox trot – 20/40
Jessie James Decker & Alan Bersten – cha cha – 20/40
Teresa Giudice & Pasha Pashkov – tango – 20/40
Jason Lewis & Peta Murgatroyd – cha cha – 18/40
Vinny Guadagnino & Koko Iwasaki – salsa – 17/40
Also Read:
‘Dancing With the Stars’ Boss on Bringing a ‘Visceral’ Live Competition Series to Disney+
Sugar disrupts microbiome, eliminates protection against obesity and diabetes
Cell (2022). DOI: 10.1016/j.cell.2022.08.005″ width=”800″ height=”530″/>
Graphical abstract. Credit: Cell (2022). DOI: 10.1016/j.cell.2022.08.005
A study of mice found that dietary sugar alters the gut microbiome, setting off a chain of events that leads to metabolic disease, pre-diabetes, and weight gain.
The findings, published today in Cell, suggest that diet matters, but an optimal microbiome is equally important for the prevention of metabolic syndrome, diabetes, and obesity.
Diet alters microbiome
A Western-style high-fat, high-sugar diet can lead to obesity, metabolic syndrome, and diabetes, but how the diet kickstarts unhealthy changes in the body is unknown.
The gut microbiome is indispensable for an animal’s nutrition, so Ivalyo Ivanov, Ph.D., associate professor of microbiology & immunology at Columbia University Vagelos College of Physicians and Surgeons, and his colleagues investigated the initial effects of the Western-style diet on the microbiome of mice.
After four weeks on the diet, the animals showed characteristics of metabolic syndrome, such as weight gain, insulin resistance, and glucose intolerance. And their microbiomes had changed dramatically, with the amount of segmented filamentous bacteria—common in the gut microbiota of rodents, fish, and chickens—falling sharply and other bacteria increasing in abundance.
Microbiome changes alter Th17 cells
The reduction in filamentous bacteria, the researchers found, was critical to the animals’ health through its effect on Th17 immune cells. The drop in filamentous bacteria reduced the number of Th17 cells in the gut, and further experiments revealed that it’s the Th17 cells that are necessary to prevent metabolic disease, diabetes, and weight gain.
“These immune cells produce molecules that slow down the absorption of ‘bad’ lipids from the intestines and they decrease intestinal inflammation,” Ivanov says. “In other words, they keep the gut healthy and protect the body from absorbing pathogenic lipids.”
Sugar vs. fat
What component of the high-fat, high-sugar diet led to these changes? Ivanov’s team found that sugar was to blame.
“Sugar eliminates the filamentous bacteria, and the protective Th17 cells disappear as a consequence,” says Ivanov. “When we fed mice a sugar-free, high-fat diet, they retain the intestinal Th17 cells and were completely protected from developing obesity and pre-diabetes, even though they ate the same number of calories.”
But eliminating sugar did not help all mice. Among those lacking any filamentous bacteria to begin with, elimination of sugar did not have a beneficial effect, and the animals became obese and developed diabetes.
“This suggests that some popular dietary interventions, such as minimizing sugars, may only work in people who have certain bacterial populations within their microbiota,” Ivanov says.
In those cases, certain probiotics might be helpful. In Ivanov’s mice, supplements of filamentous bacteria led to the recovery of Th17 cells and protection against metabolic syndrome, despite the animals’ consumption of a high-fat diet.
Though people do not have the same filamentous bacteria as mice, Ivanov thinks that other bacteria in people may have the same protective effects.
Providing Th17 cells to the mice also provided protection and may also be therapeutic for people. “Microbiota are important, but the real protection comes from the Th17 cells induced by the bacteria,” Ivanov says.
“Our study emphasizes that a complex interaction between diet, microbiota, and the immune system plays a key role in the development of obesity, metabolic syndrome, type 2 diabetes, and other conditions,” Ivanov says. “It suggests that for optimal health it is important not only to modify your diet but also improve your microbiome or intestinal immune system, for example, by increasing Th17 cell-inducing bacteria.”
A low-calorie diet alters the gut microbiome and delays immune aging
More information:
Yoshinaga Kawano et al, Microbiota imbalance induced by dietary sugar disrupts immune-mediated protection from metabolic syndrome, Cell (2022). DOI: 10.1016/j.cell.2022.08.005
Yoshinaga Kawano et al, Microbiota imbalance induced by dietary sugar disrupts immune-mediated protection from metabolic syndrome, Cell (2022). DOI: 10.1016/j.cell.2022.08.005
Journal information:
Cell
Cell
Provided by
Columbia University Irving Medical Center
Columbia University Irving Medical Center
Citation:
Sugar disrupts microbiome, eliminates protection against obesity and diabetes (2022, August 29)
retrieved 30 August 2022
from https://phys.org/news/2022-08-sugar-disrupts-microbiome-obesity-diabetes.html
This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no
part may be reproduced without the written permission. The content is provided for information purposes only.
U.S. eliminates human controls requirement for fully automated vehicles
An attendee takes a selfie inside a Cruise Origin autonomous vehicle, a Honda and General Motors self-driving car partnership, during its unveiling in San Francisco, California, U.S. January 21, 2020. REUTERS/Stephen Lam
Register now for FREE unlimited access to Reuters.com
WASHINGTON, March 10 (Reuters) – U.S. regulators on Thursday issued final rules eliminating the need for automated vehicle manufacturers to equip fully autonomous vehicles with manual driving controls to meet crash standards.
Automakers and tech companies have faced significant hurdles to deploying automated driving system (ADS) vehicles without human controls because of safety standards written decades ago that assume people are in control.
Last month, General Motors Co (GM.N) and its self-driving technology unit Cruise petitioned the U.S. National Highway Traffic Safety Administration (NHTSA) for permission to build and deploy a self-driving vehicle without human controls like steering wheels or brake pedals.
Register now for FREE unlimited access to Reuters.com
The rules revise regulations that assume vehicles “will always have a driver’s seat, a steering wheel and accompanying steering column, or just one front outboard passenger seating position.”
“For vehicles designed to be solely operated by an ADS, manually operated driving controls are logically unnecessary,” the agency said.
The new rules, which were first proposed in March 2020, emphasize automated vehicles must provide the same levels of occupant protection as human-driven vehicles.
“As the driver changes from a person to a machine in ADS-equipped vehicles, the need to keep the humans safe remains the same and must be integrated from the beginning,” said NHTSA Deputy Administrator Steven Cliff.
NHTSA’s rule says children should not occupy what is traditionally known as the “driver’s” position, given that the driver’s seating position has not been designed to protect children in a crash, but if a child is in that seat, the car will not immediately be required to cease motion.
NHTSA said existing regulations do not currently bar deploying automated vehicles as long as they have manual driving controls, and as it continues to consider changing other safety standards, manufacturers may still need to petition NHTSA for an exemption to sell their ADS-equipped vehicles.
Register now for FREE unlimited access to Reuters.com
Reporting by David Shepardson; Editing by Karishma Singh
Our Standards: The Thomson Reuters Trust Principles.
Los Angeles School District Eliminates One-Third of Its Police Officers
SACRAMENTO — After a monthslong push to defund the police in California’s largest public school system, trustees of the Los Angeles Unified School District on Tuesday approved a plan to cut 133 police positions, ban the use of pepper spray on students and divert $25 million to programs supporting students of color.
The decision, which substantially reimagines school safety in Los Angeles, was a follow-up to a vote last summer during nationwide protests over the police killing of George Floyd in Minneapolis. Amid calls for racial justice, the school board slashed the district’s 400-member police force by 35 percent, prompting the resignation of 20 officers and the chief, who objected to eliminating the jobs of scores of officers.
Tuesday’s vote was the result of months of meetings on how best to reconfigure public safety in the district, which serves about 650,000 students. The resulting plan eliminates 70 sworn officers, who have arrest powers; 62 nonsworn officers; and one support staff member, leaving 211 officers on the district’s force.
Officers at secondary schools in Los Angeles will be replaced with “climate coaches” from the community who will mentor students, help resolve conflicts and address implicit bias.
The school district in Oakland, Calif., eliminated its police force in June. But members of the Los Angeles school board, who met virtually on Tuesday, have been divided on whether to reduce the police presence on campus.
“This is a big undertaking and required a lot of coordination,” said Kelly Gonez, a board member, “but I know we know and all believe that our Black students are certainly worth this effort.”
George McKenna, another board member, warned that “parents expect us to have safe schools, and if you think the police are the problem, I think you got a problem yourself.”
In a statement, the school district’s new police chief, Leslie Ramirez, said the department had already made changes that would limit the presence of uniformed officers on campus. Chief Ramirez added that the new plan had “potential liabilities, lacks clarity and will result in unintended consequences impacting the safety of students and staff.”
The $25 million in cuts will also help fund a Black student achievement plan, which will include expanded counseling, teacher development, curriculum changes and other programs to support inclusion. Campus police officers will still monitor schools and be available for emergencies.
A previous districtwide survey found that majorities of parents, students and school staff felt that the police made their schools safer but that only 50 percent of Black parents shared positive views of the school police and only 35 percent of Black students said they felt safer.
On Monday, the district’s superintendent, Austin Beutner, praised the Black student achievement plan in his weekly address.
“We’ve been systematically failing Black children as a country,” Mr. Beutner said. “Schools must be part of the solution, because a great education is the most important part of the path out of poverty.”