- AMD’s latest driver lowers high idle power on Radeon RX 7800/7700/7600 GPUs connected to high refresh rate monitors VideoCardz.com
- AMD finally adds hardware accelerated GPU scheduling support to some of its GPUs — three years after the feature first debuted in Windows Tom’s Hardware
- AMD just made a huge move to give gaming laptops and Windows 11 handhelds better battery life TechRadar
- AMD new GPU driver adds HYPR-RX Eco mode, HAGS support and UI update VideoCardz.com
- AMD RX 7000-series’ high idle power draw finally appears to be fixed with the latest 23.12.1 drivers Tom’s Hardware
Tag Archives: connected
Khloe Kardashian admits she feels ‘less connected’ to her newborn son – Daily Mail
- Khloe Kardashian admits she feels ‘less connected’ to her newborn son Daily Mail
- Khloe Kardashian Admits She Felt ‘Less Connected’ to Her Son, Calls Surrogacy a ‘Transactional Experience’ Yahoo Entertainment
- Khloé Kardashian Felt Less Connected To Baby Because Of Surrogacy BuzzFeed
- Khloé Kardashian struggled to ‘connect’ with surrogate-born son: It was a ‘transactional’ experience Page Six
- Khloe Kardashian takes savage swipe at Kourtney for ‘not being there’ for her baby son due to ‘being in a l… The US Sun
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New York lawmaker connected to nonprofit accused of lying about homeless vets being pushed out of hotel for migrants says he’s no longer affiliated with foundation – CNN
- New York lawmaker connected to nonprofit accused of lying about homeless vets being pushed out of hotel for migrants says he’s no longer affiliated with foundation CNN
- Laura Ingraham Has ‘No Clue’ Why Vets Group Made Up Story Fox Ran Wild With Yahoo News
- Claims vets were moved from hotel for asylum seekers appear erroneous CBS New York
- Attorney general probing false claims about displaced veterans Times Union
- New York homeless men say they were offered money to pose as military veterans and falsely claim they were pushed out of a hotel to make room for migrants CNN
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4 Arrested After Hours-Long Standoff Connected to Killing of Chicago Police Officer – NBC Chicago
- 4 Arrested After Hours-Long Standoff Connected to Killing of Chicago Police Officer NBC Chicago
- Chicago cop murder: 4 juveniles, 1 adult in custody after officer’s shooting death, source says Fox News
- 4 in custody in shooting of off-duty Chicago Police Officer Areanah Preston, sources say ABC 7 Chicago
- Top cop’s wife coached slain CPD officer’s high school cheerleading team: ‘She did not deserve this’ FOX 32 Chicago
- Four in custody in connection with investigation into fatal shooting of officer Areanah Preston CBS Chicago
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Kylie Jenner Says She Feels Most ‘Connected’ to Kim Kardashian, but Her Favorite Sister ‘Changes over Time’ – Yahoo Entertainment
- Kylie Jenner Says She Feels Most ‘Connected’ to Kim Kardashian, but Her Favorite Sister ‘Changes over Time’ Yahoo Entertainment
- Kylie Jenner Shaded Kendall By Admitting That She’s “Without A Doubt” The Sister She Has The “Least In Common” With BuzzFeed News
- Kylie Jenner Reveals Her Favorite Sister, the Sister She Has the Least in Common With, Reveals Her Experience with Post-Partum Depression, Speaks to Her Relationship with Caitlyn Jenner & More Just Jared
- Kylie Jenner Hinted That She’s Been Leaning on Kim Kardashian After Their Breakups With Pete Davidson & Travis Scott SheKnows
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CDC says an eye drop brand may be connected to drug-resistant bacterial infections
A brand of over-the-counter eye drops may be linked to a bacterial infection that left one person dead and three others with permanent vision loss, according to the Centers for Disease Control and Prevention.
The CDC has identified at least 50 people in 11 states with Pseudomonas aeruginosa, which is a type of bacterium resistant to most antibiotics. So far, there have been cases in California, Colorado, Connecticut, Florida, New Jersey, New Mexico, New York, Nevada, Texas, Utah and Washington.
The agency said it is investigating, and that a majority of people affected reported using preservative-free EzriCare Artificial Tears before they became infected, according to a Jan. 20 statement.
Among the reported cases, 11 people developed eye infections, including at least three who were blinded in one eye. Others who became ill had respiratory infections or urinary tract infections, and one person died after the bacterium entered their bloodstream.
YEARLY COVID VACCINE AS PROPOSED BY FDA? ‘CART BEFORE THE HORSE,’ SAYS DOCTOR
A brand of over-the-counter eyedrops may be linked to a bacterial infection that left one person dead and three others with permanent vision loss, according to the Center for Disease Control and Prevention.
(iStock)
It remains unclear at this time if those affected had underlying eye conditions, such as glaucoma or cataracts, that would have made them more susceptible. Eye infection symptoms include pain, swelling, discharge, redness, blurry vision, sensitivity to light and the feeling that an object is stuck in the eye.
Pseudomonas aeruginosa bacteria are commonly found in water, soil and on the hands of otherwise healthy people. These infections typically take place in hospitals among people with weakened immune systems. This type of bacterium is often resistant to standard antibiotics.
The CDC has identified at least 50 people in 11 states with Pseudomonas aeruginosa, which is a type of bacterium resistant to most antibiotics.
(iStock)
The eye drops in question are labeled as preservative-free, meaning the product does not contain anything that could prevent microbiological growth.
It is possible that the drops were contaminated during the manufacturing process or when a person with the bacteria on their skin opened the container.
The CDC discovered the bacteria in the eye drop bottles and is conducting tests to determine whether that bacteria matches the strain found in patients.
RON DESANTIS PUSHES FOR SWEEPING PROTECTIONS AGAINST COVID-19 MANDATES IN FLORIDA
Eye infection symptoms include pain, swelling, discharge, redness, blurry vision, sensitivity to light and the feeling that an object is stuck in the eye.
(iStock)
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EzriCare Artificial Tears had not been recalled as of Tuesday evening.
The CDC is recommending that clinicians and patients stop using the product until the investigation and laboratory analysis are complete.
Teen suspect connected to fatal UNM shooting makes first court appearance
ALBUQUERQUE, N.M. — The 17-year-old UNM student at the center of Saturday’s deadly shooting appeared before a judge Tuesday.
Investigators said the teen lured Aggie basketball player Michael Peake to UNM campus over the weekend, so a group of other UNM students could beat him up.
A shootout ensued, and Peake was hit by a baseball bat and shot in the leg. He allegedly fired back with his own gun, hitting and killing 19-year-old UNM student Brandon Travis.
Prosecutors wanted the 17-year-old held before trial.
“I’m going to hold the child but authorize CCP. If the child is on CCP, she is going to have to comply with those requirements,” said Judge Catherine Begaye.
Begaye said the juvenile Community Custody Program has to first determine whether the teen can be appropriately supervised if she is released before trial.
Newly Discovered Protein Connected to Significant Increase in Risk of Alzheimer’s Disease
A mutation in the small protein SHMOOSE is linked with increased
Called SHMOOSE, the protein is a tiny “microprotein” encoded by a newly discovered gene within the cell’s energy-producing mitochondria. A mutation within this gene partially inactivates the SHMOOSE microprotein and is linked to a 30% higher risk for Alzheimer’s disease across four different cohorts. According to the researchers, almost 25% of people of European ancestry have the mutated version of the protein.
Alzheimer’s disease is the most prevalent type of dementia. It’s a progressive disease beginning with mild memory loss and possibly leading to loss of the ability to carry on a conversation and respond to the environment. According to the CDC, in 2020, as many as 5.8 million Americans were living with Alzheimer’s disease.
The research was published on September 21 in the journal Molecular Psychiatry.
Both the substantial risk and high prevalence of this previously unidentified mutation differentiate it from other proteins involved in Alzheimer’s disease, according to the researchers. Besides for APOE4 — the most potent known genetic risk factor for the disease — only a limited number of other gene mutations have been identified and these only mildly increased risk by less than 10%. Additionally, because the microprotein is approximately the size of the insulin peptide, it can be easily administered. This significantly increases its therapeutic potential.
“This discovery opens exciting new directions for developing precision medicine-based therapies for Alzheimer’s disease, focusing on SHMOOSE as a target area,” said Pinchas Cohen. He is the senior author of the study and professor of gerontology, medicine and biological sciences. “Administration of SHMOOSE analogs in individuals who carry the mutation and produce the mutant protein may prove to have benefit in neurodegenerative and other diseases of aging.”
Brendan Miller, USC ’22 PhD in neuroscience graduate, is the first author of the study. He used big data techniques to identify genetic variations in mitochondrial
Alzheimer’s disease is currently ranked as the sixth leading cause of death in the United States. However, recent estimates by the CDC indicate that the disorder may rank third, just behind heart disease and cancer, as a cause of death for older people. Although there is currently no cure for Alzheimer’s disease, there has been significant progress in recent years in developing and testing new treatments.
An emerging field of study
According to Miller, the importance of the relatively new field of microproteins is highlighted by the findings. For decades, scientists have studied biology mostly by considering a set of 20,000 large protein-coding genes. However, hundreds of thousands more possible genes that encode tiny microproteins have been brought to light by modern technologies.
“The field of microproteins is still so new,” Miller said. “We don’t yet know how many microprotein genes are even functional, and the cost to study a potential microprotein one-by-one from a list of thousands is just too expensive and inefficient. The approach my colleagues and I used to detect SHMOOSE shows the power of integrating big genetics data with molecular and biochemical techniques to discover functional microproteins.”
USC Leonard Davis scientists are leaders in the study of microproteins, especially those coded within the mitochondrial genome. In 2003, Cohen and his colleagues were one of the three teams of researchers to independently discover the protein humanin, which appears to have protective health effects in Alzheimer’s, atherosclerosis, and diabetes. In just the past few years, the Cohen Laboratory discovered several other mitochondrial microproteins, including, small humanin-like peptides, or SHLPs, and a microprotein called MOTS-c, an exercise-mimetic peptide that has entered clinical trials for obesity and fatty liver.
Reference: “Mitochondrial DNA variation in Alzheimer’s disease reveals a unique microprotein called SHMOOSE” by Brendan Miller, Su-Jeong Kim, Hemal H. Mehta, Kevin Cao, Hiroshi Kumagai, Neehar Thumaty, Naphada Leelaprachakul, Henry Jiao, Joan Vaughan, Jolene Diedrich, Alan Saghatelian, Thalida E. Arpawong, Eileen M. Crimmins, Nilüfer Ertekin-Taner, Meral A. Tubi, Evan T. Hare, Meredith N. Braskie, Léa Décarie-Spain, Scott E. Kanoski, Francine Grodstein, David A. Bennett, Lu Zhao, Arthur W. Toga, Junxiang Wan, Kelvin Yen and Pinchas Cohen, 21 September 2022, Molecular Psychiatry.
DOI: 10.1038/s41380-022-01769-3
Additional co-authors include Su-Jeong Kim, Hemal H. Mehta, Kevin Cao, Hiroshi Kumagai, Neehar Thumaty, Naphada Leelaprachakul, Henry Jiao, Thalida E. Arpawong, Eileen Crimmins, Meral A. Tubi, Evan T. Hare, Meredith N. Braskie, Léa Décarie-Spain, Scott E. Kanoski, Lu Zhao, Arthur W. Toga, Junxiang Wan, and Kelvin Yen of USC; as well as Joan Vaughan, Jolene Diedrich, and Alan Saghatelian of the Salk Institute for Biological Studies; Nilüfer Ertekin-Taner of the Mayo Clinic; and Francine Grodstein and David A. Bennett of the Rush University Medical Center.
The study was supported by NIH grants P30AG10161, P30AG072975, R01AG15819, R01AG17917, U01AG61356, R01AG069698, RF1AG061834, R01AG068405, P30AG068345, P01AG055369, DK118402, F31 AG059356, and T32 AG00037; as well as The Quebec Research Funds Postdoctoral Fellowship. Intellectual property related to SHMOOSE has been filed by the University of Southern California.