Tag Archives: combined

Disney Shakeup: Sean Bailey Out as Production President, David Greenbaum to Lead Newly Combined Live-Action Division and 20th Century Studios – Variety

  1. Disney Shakeup: Sean Bailey Out as Production President, David Greenbaum to Lead Newly Combined Live-Action Division and 20th Century Studios Variety
  2. Disney Shakeup: Sean Bailey Exits As President Of Walt Disney Motion Picture Studios, Searchlight’s David Greenbaum Takes Over & Also Will Run 20th Deadline
  3. Disney’s Sean Bailey, Longtime Movie Executive, Steps Down The New York Times
  4. Disney’s Head of Live-Action Movies to Step Down The Wall Street Journal
  5. Disney Shake-Up: Sean Bailey Leaving Studio as David Greenbaum Takes Over Live-Action Film Production Hollywood Reporter

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Northrop, Lockheed win combined $1.5B for SDA low Earth orbit data network – Breaking Defense

  1. Northrop, Lockheed win combined $1.5B for SDA low Earth orbit data network Breaking Defense
  2. Pentagon space arm awards $1.5 billion contract to Lockheed Martin and Northrop Grumman for communications satellites CNBC
  3. Space Development Agency awards contracts to Lockheed Martin, Northrop Grumman for 72 satellites SpaceNews
  4. Space Development Agency awards $1.5 billion for transport satellites C4ISRNET
  5. Northrop Grumman Selected to Build Tranche 2 Transport Layer-Beta Data Transport Satellites | Northrop Grumman Northrop Grumman Newsroom
  6. View Full Coverage on Google News

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‘Barbie’ & ‘Oppenheimer’ Combined Second Weekend Of $107M+ Could Lock Out Disney’s ‘Haunted Mansion’ – Box Office Preview – Deadline

  1. ‘Barbie’ & ‘Oppenheimer’ Combined Second Weekend Of $107M+ Could Lock Out Disney’s ‘Haunted Mansion’ – Box Office Preview Deadline
  2. ‘Barbie’ explained: Which scene did the studio want cut? Why are conservatives outraged? What are the best cameos? Yahoo Entertainment
  3. I saw Barbie and Oppenheimer opening weekend — and one is obviously better Tom’s Guide
  4. Barbie Box Office: Why Barbenheimer Surprised Everyone TIME
  5. Barbie just beat a Dark Knight box office record The A.V. Club
  6. View Full Coverage on Google News

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Russian deaths in Ukraine surpass all its war fatalities since WWII combined: study – The Hill

  1. Russian deaths in Ukraine surpass all its war fatalities since WWII combined: study The Hill
  2. Russia-Ukraine updates: Ukraine front line a ‘grinding slog’ – US Al Jazeera English
  3. More of Russia’s soldiers have died in Ukraine — a war Putin thought would be over in days — than in all its wars since World War II combined, new analysis finds Yahoo News
  4. Russian Bombardment Intensifies With 28 Airstrikes in 24 Hours: Ukraine Newsweek
  5. Russia-Ukraine war: List of key events, day 370 Al Jazeera English
  6. View Full Coverage on Google News

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Covid-19 vaccine: NZ company begins trial for combined flu vaccine

There are 1600 people undergoing the trial in Australia and New Zealand. Photo / AP

A Wellington medical company is running a trial of a combined vaccine for both flu and Covid-19.

P3 Research managing director Richard Stubbs believes the combined vaccine will reduce the workload for healthcare services.

Stubbs told Morning Report the aim was to make things as convenient as possible – both for health professionals and patients.

“This is a lengthy process, there is incremental knowledge achieved with all new treatment programmes.

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“We know that the flu vaccines are effective, we know that Covid vaccines are effective and we know that probably they can be given together but we don’t know the optimum doses.”

A total of 21,685 new Covid cases and 53 deaths have been reported in the past week.

The trial was taking place at nine different sites in New Zealand plus various sites in Australia, and would include 1600 people across both countries which both have a very good reputation for clinical trials, Stubbs said.

People taking part in the trial would be seen five times and undergo a lengthy process that involved health checks, he said.

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“It’s a well regulated process, there’s a lot designed to see individuals know what is asked of them and that they can be reassured by any or all safety aspects for the trial so it’s not a fast process.”

Stubbs expected the flu and Covid vaccines would be given together in the next one or two years.

– RNZ

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Trial begins for combined Covid-19 and flu vaccine

There are 1600 people undergoing the trial in Australia and New Zealand.
Photo: Getty Picture Alliance

A Wellington medical company is running a trial of a combined vaccine for both flu and Covid-19.

P3 Research managing director Richard Stubbs believes the combined vaccine will reduce the workload for healthcare services.

Stubbs told Morning Report the aim was to make things as convenient as possible – both for health professionals and patients.

“This is a lengthy process, there is incremental knowledge achieved with all new treatment programmes.

“We know that the flu vaccines are effective, we know that Covid vaccines are effective and we know that probably they can be given together but we don’t know the optimum doses.”

The trial was taking place at nine different sites in New Zealand plus various sites in Australia, and would include 1600 people across both countries which both have a very good reputation for clinical trials, Stubbs said.

People taking part in the trial would be seen five times and undergo a lengthy process that involved health checks, he said.

“It’s a well regulated process, there’s a lot designed to see individuals know what is asked of them and that they can be reassured by any or all safety aspects for the trial so it’s not a fast process.”

Stubbs expected the flu and Covid vaccines would be given together in the next one or two years.

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Gigantic Quake Recorded on Mars Was as Powerful as All Others Combined : ScienceAlert

A tremendous, record-breaking quake that rocked Mars in May of this year was at least five times larger than the previous record-holder, new research has revealed.

It’s unclear what the source of the quake was, but it was definitely peculiar. In addition to being the most powerful quake recorded yet on Mars, it was also the longest by a significant amount, shaking the red planet for 10 hours.

“The energy released by this single marsquake is equivalent to the cumulative energy from all other marsquakes we’ve seen so far,” says seismologist John Clinton of the Swiss Federal Institute of Technology in Switzerland, “and although the event was over 2000 kilometers (1200 miles) distant, the waves recorded at InSight were so large they almost saturated our seismometer.”

The new analysis of the quake, published in Geophysical Research Letters, set its magnitude at 4.7. The previous record-holder was a magnitude 4.2 quake detected in August 2021.

That might not sound like a big quake by Earth standards, where the most powerful quake ever recorded tipped a magnitude of around 9.5. But for a planet that had been thought seismically inactive until NASA’s InSight probe started recording its interior in early 2019, it’s impressive.

Although Mars and Earth have a lot in common, there are some really key differences. Mars doesn’t have tectonic plates; and nor does it have a coherent, global magnetic field, often interpreted as a sign that not much is happening in the Martian interior, since Earth’s magnetic field is theorized to be the result of internal thermal convection.

InSight has revealed that Mars isn’t as seismically quiet as we’d previously assumed. It creaks and rumbles, hinting at volcanic activity under the Cerberus Fossae region where the InSight lander squats, monitoring the planet’s hidden innards.

The spectrogram of the quake, recorded on 4 May 2022. (NASA/JPL-Caltech/ETH Zurich)

But determining the activity status of the Martian interior isn’t the only reason to monitor marsquakes. The way seismic waves propagate through and across the surface of a planet can help reveal density variations in its interior. In other words, they can be used to reconstruct the structure of the planet.

This is usually done here on Earth, but hundreds of quakes recorded by InSight have allowed scientists to build a map of the Martian interior, too.

The May quake may have been just one seismic event, but it seems it was an important one.

“For the first time we were able to identify surface waves, moving along the crust and upper mantle, that have traveled around the planet multiple times,” Clinton says.

In two other, separate papers in Geophysical Research Letters, teams of scientists have analyzed these waves to try to understand the structure of the crust on Mars, identifying regions of sedimentary rock and possible volcanic activity inside the crust.

But there’s more to be done on the quake itself. Firstly, it originated near, but not from, the Cerberus Fossae region, and could not be traced to any obvious surface features. This suggests that it could be related to something hidden below the crust.

Secondly, marsquakes usually have either a high or a low frequency, the former characterized by quick, short tremors, and the latter by longer, deeper waves with bigger amplitudes. This quake combined both frequency ranges, and the researchers aren’t entirely sure why. However, it’s possible that previously recorded high- and low-frequency marsquakes analyzed separately may be two parts of the same seismic event.

This could mean that scientists need to rethink how marsquakes are understood and analyzed, revealing even more secrets hiding under the deceptively quiet Martian surface.

“This was definitely the biggest marsquake that we have seen,” says planetary scientist Taichi Kawamura of the Paris Globe Institute of Physics in France.

“Stay tuned for more exciting stuff following this.”

The research has been published in Geophysical Research Letters.

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Pfizer, BioNTech launch phase 1 trial on combined COVID-19 and flu vaccine

Pfizer and BioNTech have launched a clinical trial on a vaccine targeting both COVID-19 and influenza, the companies announced Thursday.

The phase 1 trial is being done in the United States with 180 participants between the ages of 18 and 64, with the first participant dosed this week, the companies said. The follow-up period for each participant will be six months.

In this Sept. 8, 2022, file photo, a teenager receives the Pfizer-BioNTech COVID-19 booster vaccine targeting BA.4 and BA.5 Omicron sub variants at Skippack Pharmacy in Schwenksville, Penn.

Hannah Beier/Reuters

“By combining both indications in one vaccine approach, we aim to provide individuals with an efficient way to receive immunization against two severe respiratory diseases with evolving viruses that require vaccine adaptation,” Dr. Ugur Sahin, CEO and co-founder of BioNTech, said in a statement.

The combination vaccine is based on the currently available bivalent COVID-19 booster and a quadrivalent mRNA flu vaccine, which is designed to protect against four different flu viruses.

The phase 1 trial will test for safety, immune response and optimal dose level of the combination vaccine, before moving on to larger trials. The data will also provide insight into the potential of mRNA vaccines to address more than one pathogen, Sahin said.

Annaliesa Anderson, senior vice president and chief scientific officer of vaccine research and development for Pfizer, called this an “exciting step in our ongoing journey with BioNTech as we collectively look to transform the prevention of infectious diseases around the world.”

“Even with existing seasonal influenza vaccines, the burden of this virus is severe across the world causing thousands of deaths and hospitalizations every year,” she said in a statement.

In this Sept. 9, 2022, file photo, a man gets an influenza vaccine from a pharmacist during an event hosted by the Chicago Department of Public Health at the Southwest Senior Center in Chicago.

Scott Olson/Getty Images

Studies indicate​ COVID-19 vaccine efficacy fades over time, though it’s not clear if every American will need an annual COVID-19 booster. As scientists continue to assess the need, several companies are at work on creating a single injection each fall that protects against both seasonal flu and COVID-19.

In addition to Pfizer, pharmaceutical companies Moderna and Novavax have announced plans to work on a combo shot.

Moderna said it anticipates starting clinical trials on a single-dose vaccine that combines a booster against COVID-19 and a booster against flu by the end of the year, with hopes of the vaccine being available for the 2023 season.

“We believe this is a very large opportunity that is ahead of us, if we could bring to market a high efficacy pan-respiratory annual booster,” Moderna COE Stéphane Bancel said during the Sept. 9 investor meeting.

Last year, Novavax enrolled people in a Phase 1/2 study to evaluate the safety, tolerability and immune response of a combination vaccine using the company’s seasonal influenza and COVID-19 vaccines. A phase 2 confirmation trial is expected to begin later this year, the company said in October.

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Astros toss combined no-hitter in Game 4 vs. Phillies, make history after brilliant Cristian Javier start

The Houston Astros — led by starter Cristian Javier — have thrown the second no-hitter in World Series history. Javier and three relief pitchers combined to blank the Philadelphia Phillies in Game 4 Wednesday night, 5-0, to pull Houston even in the series in historic fashion.

The combined no-no joins Don Larsen’s perfect game for the 1956 New York Yankees in World Series lore. It is the third postseason no-hitter, and comes in the same ballpark as the second: Roy Halladay’s NLDS no-no for the Phillies in 2010.

Javier, the preternaturally calm 25-year-old Astros starter, fired six no-hit innings to help Houston quiet the Philadelphia crowd and rebound from a rough Game 3, striking out nine and walking two. After 97 pitches, manager Dusty Baker shook his hand and turned to the bullpen. Bryan Abreu, Rafael Montero and Ryan Pressly each pitched an inning to close it out. Overall, the Astros struck out 14 Phillies and retired 18 in a row between walks in the third and ninth innings.

Javier will cap his first full season as a major-league starter by entering the record books as the author of the longest hitless World Series start outside of Larsen’s perfecto.

He eclipses Atlanta Braves pitcher Ian Anderson, who went five innings without allowing a hit in 2021’s World Series Game 3 against the Astros. The Braves bullpen eventually allowed the first hit leading off the eighth.

This was no fluke, either. Javier tossed seven spotless frames to start a combined no-hitter against the Yankees earlier this season, and allowed the lowest batting average in baseball in the second half among starting pitchers.

Coming off a major breakout that established him as a bonafide starter, Javier is nicknamed “El Reptil” — The Reptile — because early in his career coaches deemed him cold-blooded, a descriptor that now seems particularly apt. He tamed the Phillies — who shelled Lance McCullers Jr. one night earlier in a Game 3 win — mostly with his fastball. He whips it high in the zone, creating the feeling that it’s rising. Then he plays off it with a biting slider and the occasional curveball. Out of Javier’s 97 pitches in Game 4, 70 were fastballs.

Astros starter Cristian Javier’s pitch chart against the Phillies in World Series Game 4. (Courtesy Baseball Savant)

All of Houston’s runs came in the fifth inning. They chased Phillies starter Aaron Nola by lashing three straight singles. When Phillies relief star Jose Alvarado came in, he plunked Yordan Alvarez to drive in the first run, then Alex Bregman followed with a two-RBI double.

The Astros win guarantees the series will return to Houston, requiring at least six games to crown a champion. Game 5 will still be in Philadelphia, though. That starts Thursday night at 8 p.m. ET on FOX.

How’d we get here? Catch up on everything you need to know for the World Series:



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Activision Blizzard’s mobile games make more money than console and PC sales combined

More than half of Activision Blizzard’s revenue came from mobile games in April – June (Q2) 2022.

According to Activision Blizzard’s most recent financial report, the developer/publisher generated £535m from its PC and console sales in Q2 2022 – £275m ($332m) on PC and £310m ($376m) consoles – while £688m ($831m) came from its “mobile and ancillary” business, which the company says “primarily include[s] revenues from mobile devices”. That’s more than 50 per cent of its entire net revenue for the period.

Eurogamer Newscast: Would you eat a Pokémon?

Part of this, of course, is because Activision acquired mobile developer King in 2016 – and right now, it’s the most successful part of ABK’s business – but it’s likely not coincidental that Diablo Immortal released during this period, too (thanks, PC Gamer).

Just a year ago across the same period, mobile, console, and PC earnings were £658m/$795m, £612m/$740m, and £520m/$628m respectively, which means only its mobile business has increased its net revenue year-on-year: console revenue, on the other hand, has almost halved.

The same financial report recently revealed that Diablo Immortal has stemmed the flow of falling Blizzard user numbers, and given the company a modest increase in monthly active engagement.

However, the results also showed Blizzard’s active users have only recovered slightly – to where they were just over a year ago – and revenue remains down slightly year-on-year.

After falling to 22 million monthly active users for the quarter ending in March 2022, Diablo Immortal has helped Blizzard back to 27 million for the quarter ending at the beginning of July.

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