Tag Archives: chronic

Game Of Thrones’ Hannah Waddingham Left With “Chronic Claustrophobia” After She Was Actually Waterboarded For A Torture Scene – BuzzFeed News

  1. Game Of Thrones’ Hannah Waddingham Left With “Chronic Claustrophobia” After She Was Actually Waterboarded For A Torture Scene BuzzFeed News
  2. Hannah Waddingham Says ‘Horrific’ Waterboarding on ‘Game of Thrones’ Led to ‘Chronic Claustrophobia’: ‘I Wasn’t Expecting’ That Variety
  3. Hannah Waddingham and Lena Headey look back on traumatic ‘Game of Thrones’ ‘wineboarding’ scene Entertainment Weekly News
  4. Hannah Waddingham Details Trauma From Filming Game of Thrones Waterboarding Scene – E! Online E! NEWS
  5. Hannah Waddingham Says ‘Game of Thrones’ Scene Led to Claustrophobia PEOPLE

Read original article here

Hannah Waddingham Says She Has “Chronic Claustrophobia” After ‘Game of Thrones’ – Hollywood Reporter

  1. Hannah Waddingham Says She Has “Chronic Claustrophobia” After ‘Game of Thrones’ Hollywood Reporter
  2. Game of Thrones: Hannah Waddingham on Literally Being Waterboarded Collider
  3. Hannah Waddingham Says Filming “Horrific” ‘Game Of Thrones’ Waterboarding Scene Left Her With “Chronic Claustrophobia” Deadline
  4. Game of Thrones Star Hannah Waddingham Left With Chronic Claustrophobia By Torture Scene IGN
  5. Game of Thrones star Hannah Waddinham says ‘horrific’ experience left her with long-lasting damage The Independent

Read original article here

Hannah Waddingham Says ‘Horrific’ Waterboarding on ‘Game of Thrones’ Led to ‘Chronic Claustrophobia’: ‘I Wasn’t Expecting’ That – Variety

  1. Hannah Waddingham Says ‘Horrific’ Waterboarding on ‘Game of Thrones’ Led to ‘Chronic Claustrophobia’: ‘I Wasn’t Expecting’ That Variety
  2. Hannah Waddingham has ‘chronic claustrophobia’ from ‘Game of Thrones’ scene Entertainment Weekly News
  3. Hannah Waddingham Says ‘Horrific’ Waterboarding on ‘Game of Thrones’ Led to ‘Chronic Claustrophobia’: ‘I Wasn’t Expecting’ That Yahoo Entertainment
  4. Game of Thrones: Hannah Waddingham on Literally Being Waterboarded Collider
  5. Hannah Waddingham Says ‘Game of Thrones’ Scene Led to Claustrophobia PEOPLE

Read original article here

Exposure-response associations between chronic exposure to fine particulate matter and risks of hospital admission for major cardiovascular diseases: population based cohort study – The BMJ

  1. Exposure-response associations between chronic exposure to fine particulate matter and risks of hospital admission for major cardiovascular diseases: population based cohort study The BMJ
  2. ‘Safe’ air-quality levels in US, UK and EU still harmful for health, study says The Guardian
  3. Air pollution linked to increased hospital admission for major heart and lung diseases Medical Xpress
  4. Understanding the Impact of PM2.5 on Non-Respiratory Infections: A Deep Dive into Recent Research Medriva
  5. ‘No safe threshold’: Air pollution increases risk for hospitalization among older adults Healio

Read original article here

‘Days of Our Lives’ Actor Cody Longo Died Due to ‘Chronic’ Alcohol Abuse (Report) – Yahoo Entertainment

  1. ‘Days of Our Lives’ Actor Cody Longo Died Due to ‘Chronic’ Alcohol Abuse (Report) Yahoo Entertainment
  2. ‘Days of Our Lives’ Actor Cody Longo Died from Longtime Drinking TMZ
  3. ‘Hollywood Heights’ Actor Cody Longo’s Cause of Death Revealed Parade Magazine
  4. Days Of Our Lives actor Cody Longo died from ‘chronic drinking’ and was found ‘surrounded by alcohol,’ auto… The US Sun
  5. Days of Our Lives actor Cody Longo died as a result of alcohol abuse according to coroner’s report Daily Mail
  6. View Full Coverage on Google News

Read original article here

COVID-19 Can Cause Brain Cells To Fuse – Leading to Chronic “Long COVID” Neurological Symptoms – SciTechDaily

  1. COVID-19 Can Cause Brain Cells To Fuse – Leading to Chronic “Long COVID” Neurological Symptoms SciTechDaily
  2. Mechanistic insights into how the SARS-CoV-2 virus affects the nervous system, alters its function, and causes neuropathology News-Medical.Net
  3. COVID-19 could cause brain cell fusion, study finds | 9 News Australia 9 News Australia
  4. COVID-19 can fuse brain cells, leading to chronic neurological problems Study Finds
  5. Researchers make scary discovery about impact of Long COVID on the brain | 7NEWS 7NEWS Australia
  6. View Full Coverage on Google News

Read original article here

Remote haemodynamic monitoring of pulmonary artery pressures in patients with chronic heart failure (MONITOR-HF): a randomised clinical trial – The Lancet

  1. Remote haemodynamic monitoring of pulmonary artery pressures in patients with chronic heart failure (MONITOR-HF): a randomised clinical trial The Lancet
  2. Remote pulmonary artery pressure monitoring improves quality of life, reduces heart failure hospitalizations News-Medical.Net
  3. In early trial, drug appears to reduce harmful protein buildup in heart STAT
  4. Remote pulmonary artery pressure monitoring lowers hospitalisations for heart failure: Study ETHealthWorld
  5. Study shows potential benefit of sacubitril/valsartan in heart failure patients with EF over 40% News-Medical.Net
  6. View Full Coverage on Google News

Read original article here

Cognitive functional therapy with or without movement sensor biofeedback versus usual care for chronic, disabling low back pain (RESTORE): a randomised, controlled, three-arm, parallel group, phase 3, clinical trial – The Lancet

  1. Cognitive functional therapy with or without movement sensor biofeedback versus usual care for chronic, disabling low back pain (RESTORE): a randomised, controlled, three-arm, parallel group, phase 3, clinical trial The Lancet
  2. Innovative therapy brings hope to chronic lower back pain sufferers New Atlas
  3. Study offers fresh hope for people living with chronic back pain Medical Xpress
  4. New drug-free treatment offers long-term hope for Australians struggling with back pain | 7NEWS 7NEWS Australia
  5. Curtin University researchers say back pain treatment trial gives hope to millions ABC News
  6. View Full Coverage on Google News

Read original article here

Commercial Dishwashers Can Damage the Gut and Lead to Chronic Disease

Rinse aids in commercial dishwashers often contain alcohol ethoxylate. This substance damages the intestinal epithelium, which can lead to chronic diseases.

According to researchers from the Swiss Institute of Allergy and Asthma Research working with organoids, residue from rinse agents on dishes after cleaning in professional-grade dishwashers can harm the natural protective layer in the gut and contribute to the development of chronic diseases

Commercial dishwashers are a convenient way to quickly clean and dry plates, glasses, and cutlery in various settings such as restaurants, schools, and barracks. However, a recent study conducted by researchers at the Swiss Institute of Allergy and Asthma Research (SIAF), an associated institute of the University of Zurich (UZH) has revealed that these appliances come with a risk. The study found that an ingredient in commercial rinse agents has a toxic effect on the gastrointestinal tract.

Chemical residue on clean plates

A typical cycle in a commercial dishwasher involves circulating hot water and detergent for around 60 seconds at high pressure. Afterward, there is a second 60-second washing and drying cycle in which water and a rinse agent are applied. “What’s especially alarming is that in many appliances, there’s no additional wash cycle to remove the remaining rinse aid,” says Cezmi Akdis, UZH professor of experimental allergology and immunology and director of the SIAF, who led the study. “This means that potentially toxic substances remain on the dishes, where they then dry in place.” When the dishes are used the next time, this dried chemical residue can easily end up in the gastrointestinal tract.

This inspired the research team under Akdis to investigate what effect the components of commercial-grade detergents and rinse agents have on the epithelial barrier in the gut – the layer of cells that lines the intestinal tract and controls what enters the body. A defect in this barrier is associated with conditions such as food allergies, gastritis, diabetes, obesity, cirrhosis of the liver, rheumatoid arthritis, multiple sclerosis, autism spectrum disorders, chronic depression, and

Toxic substances in rinse agents

The researchers used a newly developed technology for their study – human intestinal organoids and intestinal cells on microchips. The tissue forms a three-dimensional clump of cells that is very similar to the intestinal epithelium in humans. The team used various biomolecular methods to analyze the effect that commercial detergents and rinse aids have on these cells. They diluted these substances to reflect the amounts that would be present on dry dishes (1:10,000 to 1:40,000).

The result was that high doses of rinse agents killed the intestinal epithelial cells and lower doses made it more permeable. Researchers also observed the activation of several genes and cell signaling proteins that could trigger inflammatory responses. A more detailed analysis showed that one component of the rinse agent – alcohol ethoxylates – was responsible for this reaction.

According to Akdis, these findings have significant implications for public health. “The effect that we found could mark the beginning of the destruction of the gut’s epithelial layer and trigger the onset of many chronic diseases,” he says. Akdis calls for an immediate response: “It is important to inform the public about this risk since alcohol ethoxylates seem to be commonly used in commercial dishwashers.”

Reference: “Gut epithelial barrier damage caused by dishwasher detergents and rinse aids” by Ismail Ogulur, Yagiz Pat, Tamer Aydin, Duygu Yazici, Beate Rückert, Yaqi Peng, Juno Kim, Urszula Radzikowska, Patrick Westermann, Milena Sokolowska, Raja Dhir, Mubeccel Akdis, Kari Nadeau and Cezmi A. Akdis, 1 December 2022, Journal of Allergy and Clinical Immunology.
DOI: 10.1016/j.jaci.2022.10.020



Read original article here

Dealing with chronic constipation – The Washington Post

Comment

Consumer Reports has no financial relationship with any advertisers on this site.

It’s normal to have an occasional bout of constipation. Uncomfortable as it may be, this usually resolves within a few days. But the problem may be chronic — and require some action — if you have at least two of the following symptoms for at least three months:

  • You have fewer than three bowel movements per week.
  • You need to strain for at least a quarter of all your bowel movements.
  • Stool is often hard or lumpy.
  • Sometimes you feel like your bowels haven’t been fully emptied.

For relief, people with chronic constipation may turn to laxatives.

“Many older adults assume that constipation is just another inevitable part of aging, but it can be avoided through lifestyle [strategies and] occa­sion­ally medication,” says Christian Stevoff, a gastroenterologist at Northwestern Medicine in Chicago.

Know the causes of chronic constipation

Chronic constipation might be more common in older adults, affecting about 26 percent of women and 16 percent of men over age 65, and 34 percent of women and 26 percent of men older than 85, according to a 2021 study.

“As we age, our gut and nervous system also age, and one of the consequences of that is the degeneration of nerves and muscles (that move waste along) so that they don’t function as well as they used to,” says Satish Rao, chief of gastroenterology at Augusta University in Georgia.

But other factors, includ­ing insufficient fiber and too little physical activity, can also contribute. Medications such as opioids and certain antidepressants, blood pressure meds and Parkinson’s disease drugs are all potential culprits, Stevoff says.

Some over-the-counter (OTC) pain relievers, such as ibuprofen and naproxen, are also associated with constipation, and supplements that contain calcium or iron “can bind you up,” says William Chey, a gastroenterologist at the University of Michigan in Ann Arbor.

Hypothyroidism or neurological issues such as multiple sclerosis can lead to constipation, too, as can pelvic floor disorders — which affect the ability to coordinate muscles to push stool out, says David Poppers, a gastroenterologist at NYU Langone Health in New York.

Try these lifestyle steps

Lifestyle strategies can be quite effective if you continue them, but they can take several weeks to begin working. If you need immediate relief — for example, you haven’t passed stool in several days — you might consider using an OTC osmotic laxative with polyethylene glycol (PEG), Stevoff says. (For some, stimulant laxatives, such as senna and bisacodyl, may have harsher side effects than PEG-based medications.)

Always let your doctor know if you haven’t had a bowel movement in several days. For the long haul, try these strategies:

  • Increase your fiber. It helps bulk up stool, making it easier to pass. Research suggests that eating five or six prunes each day is as good for chronic constipation as some laxatives, Rao says. Or try eating two kiwi­fruits a day; Chey’s research finds that it relieves constipation in about half of people, without some of the side effects of prunes, such as abdominal pain, bloating and gas.
  • Ramp up your fiber intake. Try this over a period of days to weeks to allow your body to get used to it, Chey says. If you find it hard to get enough fiber through food, consider taking an OTC fiber supplement. The best evidence is for those that contain psyllium, Poppers says.
  • Drink enough fluids. Try to drink about eight 8-ounce cups of fluid every day. A cup of coffee might also be helpful because it’s a mild gastro­­intestinal stimulant. Many older adults are perpetually dehydrated, which can worsen constipation, Chey says.
  • Pay attention to timing. Your bowels tend to be most active within about a half-hour after a meal, so make sure you have access to a toilet then. It’s fine to spend about five to 10 minutes in the bathroom, but if nothing happens in that time, try later in the day, Poppers says.
  • Adopt the right posture. You want to keep your knees above your hips, which relaxes pelvic floor muscles that loop around the back of your rectum, says Carrie Pagliano of the American Physical Therapy Association. “This way it provides a straight shot for BMs to go out,” she says. One option is to sit on the toilet with your feet on a small footstool, such as the Squatty Potty. And avoid straining­.
  • Exercise. A 2017 study found that women with chronic constipation who walked on a treadmill for 60 minutes three times a week for 12 weeks reported an improvement compared with a control group.

If you need long-term help

If you’ve tried lifestyle changes for three to four weeks and still experience some chronic constipation, see your doctor, Stevoff says. A physician can do bloodwork to rule out medical conditions, review your meds and supplements, and, if necessary, perform tests such as a colonoscopy to check for an obstruction or a blockage. If your chronic constipation is caused or worsened by pelvic floor problems, your doctor may recommend pelvic floor physical therapy, where you’ll learn techniques such as abdominal massage that can help get things moving again.

When there’s no clear cause, Rao says prescription medications could be an option — temporarily or in some cases long-term.

When the problem becomes severe

If your constipation is unresolved for too long, it can lead to fecal impaction, where a lump of dry, hard stool becomes stuck in the rectum.

In addition to constipation, this can bring abdominal pain and a feeling of fullness that affects appetite. Fecal impaction can also lead to diarrhea, because of watery stool from higher up in the gastrointestinal tract passing around stuck stool, Rao says.

A doctor can diagnose fecal impaction with a digital rectal exam and X-rays. They may try to remove the impaction manually or administer a warm-water enema to flush it out. If it doesn’t respond to these measures, or if your doctor sees signs of a perforated colon, you might need emergency surgery.

Once the stool is removed, your doctor will recommend a laxative or other steps to prevent a recurrence, such as increasing fiber intake and staying active. You’ll also want to talk to your doctor about medications that may contribute.

Copyright 2022, Consumer Reports Inc.

Consumer Reports is an independent, nonprofit organization that works side by side with consumers to create a fairer, safer, and healthier world. CR does not endorse products or services, and does not accept advertising. Read more at ConsumerReports.org.

Read original article here

The Ultimate News Site