Tag Archives: Cardiovascular disease

Complications during pregnancy linked to a higher risk of heart disease, study finds

February 1, 2023 Admin Leave a comment

CNN
—

Five major pregnancy complications are strong lifelong risk factors for ischemic heart disease, a new study finds, with the greatest risk coming in the decade after delivery.

Ischemic heart disease refers to heart problems, including heart attack, caused by narrowed or dysfunctional blood vessels that reduce blood and oxygen flow to the heart.

Gestational diabetes and preeclampsia increased the risk of ischemic heart disease in the study by 54% and 30%, respectively, while other high blood pressure disorders during pregnancy doubled the risk. Delivering a baby early – before 37 weeks – or delivering a baby with a low birth weight were associated with a 72% and 10% increased risk, respectively.

The study, published in Wednesday in the BMJ, followed a cohort of more than 2 million women in Sweden with no history of heart disease who gave birth to single live infants between 1973 and 2015.

Roughly 30% of the women had at least one adverse pregnancy outcome. Those who had multiple adverse outcomes – whether in the same or different pregnancies – showed further increased risk of ischemic heart disease.

“These pregnancy outcomes are early signals for future risk of heart disease and can help identify high-risk women earlier and enable earlier interventions to improve their long-term outcomes and help prevent the development of heart disease in these women,” said Dr. Casey Crump, an author of the study and professor of family medicine at the Icahn School of Medicine at Mount Sinai.

Heart disease is the leading cause of death among women in the United States and accounts for 1 in 5 female deaths, according to the US Centers for Disease Control and Prevention. This research adds to mounting evidence that pregnancy provides important information about a woman’s cardiovascular health.

“What happens to a woman during pregnancy is almost like a stress test or a marker for her future cardiovascular risk after pregnancy. And unfortunately, a lot of women don’t get told this by anybody,” said CNN Medical Correspondent Dr. Tara Narula, an associate professor of cardiology and the associate director of the Women’s Heart Program at Lenox Hill Hospital. She was not involved in the new study.

Although it’s not completely clear why, experts say the normal changes that occur during pregnancy may unmask underlying health issues in some women with certain risk factors.

Experiencing an adverse pregnancy outcome – even temporarily – could result in changes to blood vessels and the heart that may persist or progress after delivery, increasing a woman’s risk for cardiovascular disease.

This heightened risk is a particular concern for women in the US, experts say, where the maternal mortality rate is several times higher than in other high-income countries.

“There’s been a change in the birthing population. US women are getting pregnant at a later age, and they have already accrued maybe one or two cardiovascular risk factors. Perhaps there are other stressors in life – depression, stress, isolation, obesity – lots of different things that are impacting women in the US,” said Dr. Garima Sharma, associate professor of cardiology and director of the Cardio-Obstetrics Program at Johns Hopkins University School of Medicine, who also was not involved in the new study.

Pregnancy complications are carefully monitored during pregnancy, but there is little evaluation of and education about the effects on cardiovascular health after delivery for women, experts say.

“And so they have their delivery, they’ve had maybe preeclampsia or gestational diabetes, and nobody really follows up with them. They are not told that, in fact, they are at increased risk,” Narula said.

Gestational diabetes is a marker not only for increased risk of diabetes but also for general cardiovascular disease. Preeclampsia and eclampsia are markers for hypertension risk as well as general cardiovascular risks.

Narula, a cardiologist who specializes in caring for women, regularly considers adverse pregnancy outcomes when evaluating patients and emphasizes the continued need for this.

“The classic risk calculator that we use doesn’t have anything in there for pregnancy complications, but you know, it should for women, and hopefully someday, they will start to take that into account,” she said.

The American Heart Association recommends that all health care professionals take a detailed history of pregnancy complications when assessing a woman’s heart disease risk, but this is not consistently done in clinical practice, especially in primary care, where most women are seen, Crump says.

“Raising awareness of these findings among physicians as well as women hopefully will enable more of these women to be screened early and hopefully improve their long-term outcomes,” he said.

Roughly 1 in 3 women will have an adverse pregnancy outcome. Experts say that improving your health before getting pregnant can help avoid these issues.

“Reducing your risk should start preconception, and so getting your body and yourself into the healthiest state possible before you ever even get pregnant is really the first step,” Narula said.

This includes achieving and maintaining a healthy body weight with a good diet and regular exercise, controlling high blood pressure and diabetes, quitting smoking and managing stress.

Taking action after pregnancy is equally important, as research has estimated that only 30% to 80% of women have a postpartum checkup 6 to 8 weeks after delivery.

“Making sure that these women actually are appropriately followed after their delivery and that there is a warm handoff between [obstetrics] and [maternal-fetal medicine] to their primary care doctors or preventive cardiologists who can then talk about optimizing cardiovascular risks and reduction of these risk factors post-pregnancy in the postpartum time frame is crucial,” Sharma said.

Experts hope that increased patient and provider awareness of the connection between pregnancy and heart health will keep birth from being a cause of death.

“Cardiovascular disease is preventable. It’s a leading cause of maternal mortality, but it doesn’t have to be. If we do a better job at screening patients before they get pregnant, if we do a better job of treating them during pregnancy and postpartum, we can improve women’s outcomes,” Narula said. “It’s a tragedy to bring a new life into the world, and then the mother suffers some horrible complication and/or death that could have been prevented.”

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Health

Weight loss surgery extends lives, study finds

January 28, 2023 Admin Leave a comment

CNN
—

Weight loss surgery reduces the risk of premature death, especially from such obesity-related conditions as cancer, diabetes and heart disease, according to a new 40-year study of nearly 22,000 people who had bariatric surgery in Utah.

Compared with those of similar weight, people who underwent one of four types of weight loss surgery were 16% less likely to die from any cause, the study found. The drop in deaths from diseases triggered by obesity, such as heart disease, cancer and diabetes, was even more dramatic.

“Deaths from cardiovascular disease decreased by 29%, while deaths from various cancers decreased by 43%, which is pretty impressive,” said lead author Ted Adams, an adjunct associate professor in nutrition and integrative physiology at the University of Utah’s School of Medicine.

“There was also a huge percentage drop — a 72% decline — in deaths related to diabetes in people who had surgery compared to those who did not,” he said. One significant downside: The study also found younger people who had the surgery were at higher risk for suicide.

The study, published Wednesday in the journal Obesity, reinforces similar findings from earlier research, including a 10-year study in Sweden that found significant reductions in premature deaths, said Dr. Eduardo Grunvald, a professor of medicine and medical director of the weight management program at the University of California San Diego Health.

The Swedish study also found a significant number of people were in remission from diabetes at both two years and 10 years after surgery.

“This new research from Utah is more evidence that people who undergo these procedures have positive, beneficial long-term outcomes,” said Grunvald, who coauthored the American Gastroenterological Association’s new guidelines on obesity treatment.

The association strongly recommends patients with obesity use recently approved weight loss medications or surgery paired with lifestyle changes.

“And the key for patients is to know that changing your diet becomes more natural, more easy to do after you have bariatric surgery or take the new weight loss medications,” said Grunvald, who was not involved in the Utah study.

“While we don’t yet fully understand why, these interventions actually change the chemistry in your brain, making it much easier to change your diet afterwards.”

Despite the benefits though, only 2% of patients who are eligible for bariatric surgery ever get it, often due to the stigma about obesity, said Dr. Caroline Apovian, a professor of medicine at Harvard Medical School and codirector of the Center for Weight Management and Wellness at Brigham and Women’s Hospital in Boston. Apovian was the lead author for the Endocrine Society’s clinical practice guidelines for the pharmacological management of obesity.

Insurance carriers typically cover the cost of surgery for people over 18 with a body mass index of 40 or higher, or a BMI of 35 if the patient also has a related condition such as diabetes or high blood pressure, she said.

“I see patients with a BMI of 50, and invariably I will say, ‘You’re a candidate for everything — medication, diet, exercise and surgery.’ And many tell me, ‘Don’t talk to me about surgery. I don’t want it.’ They don’t want a surgical solution to what society has told them is a failure of willpower,” she said.

“We don’t torture people who have heart disease: ‘Oh, it’s because you ate all that fast food.’ We don’t torture people with diabetes: ‘Oh, it’s because you ate all that cake.’ We tell them they have a disease, and we treat it. Obesity is a disease, too, yet we torture people with obesity by telling them it’s their fault.”

Most of the people who choose bariatric surgery — around 80% — are women, Adams said. One of the strengths of the new study, he said, was the inclusion of men who had undergone the procedure.

“For all-causes of death, the mortality was reduced by 14% for females and by 21% for males,” Adams said. In addition, deaths from related causes, such as heart attack, cancer and diabetes, was 24% lower for females and 22% lower for males who underwent surgery compared with those who did not, he said.

Four types of surgery performed between 1982 and 2018 were examined in the study: gastric bypass, gastric banding, gastric sleeve and duodenal switch.

Gastric bypass, developed in the late 1960s, creates a small pouch near the top of the stomach. A part of the small intestine is brought up and attached to that point, bypassing most of the stomach and the duodenum, the first part of the small intestine.

In gastric banding, an elastic band that can be tightened or loosened is placed around the top portion of the stomach, thus restricting the volume of food entering the stomach cavity. Because gastric banding is not as successful in creating long-term weight loss, the procedure “is not as popular today,” Adams said.

“The gastric sleeve is a procedure where essentially about two-thirds of the stomach is removed laparoscopically,” he said. “It takes less time to perform, and food still passes through the much-smaller stomach. It’s become a very popular option.”

The duodenal switch is typically reserved for patients who have a high BMI, Adams added. It’s a complicated procedure that combines a sleeve gastrectomy with an intestinal bypass, and is effective for type 2 diabetes, according to the Cleveland Clinic.

One alarming finding of the new study was a 2.4% increase in deaths by suicide, primarily among people who had bariatric surgery between the ages of 18 and 34.

“That’s because they are told that life is going to be great after surgery or medication,” said Joann Hendelman, clinical director of the National Alliance for Eating Disorders, a nonprofit advocacy group.

“All you have to do is lose weight, and people are going to want to hang out with you, people will want to be your friend, and your anxiety and depression are going to be gone,” she said. “But that’s not reality.”

In addition, there are postoperative risks and side effects associated with bariatric surgery, such as nausea, vomiting, alcoholism, a potential failure to lose weight or even weight gain, said Susan Vibbert, an advocate at Project HEAL, which provides help for people struggling with eating disorders.

“How are we defining health in these scenarios? And is there another intervention — a weight neutral intervention?” Vibbert asked.

Past research has also shown an association between suicide risk and bariatric surgery, Grunvald said, but studies on the topic are not always able to determine a patient’s mental history.

“Did the person opt for surgery because they had some unrealistic expectations or underlying psychological disorders that were not resolved after the surgery? Or is this a direct effect somehow of bariatric surgery? We can’t answer that for sure,” he said.

Intensive presurgery counseling is typically required for all who undergo the procedure, but it may not be enough, Apovian said. She lost her first bariatric surgery patient to suicide.

“She was older, in her 40s. She had surgery and lost 150 pounds. And then she put herself in front of a bus and died because she had underlying bipolar disorder she had been self-medicating with food,” Apovian said. “We as a society use a lot of food to hide trauma. What we need in this country is more psychological counseling for everybody, not just for people who undergo bariatric surgery.”

Managing weight is a unique process for each person, a mixture of genetics, culture, environment, social stigma and personal health, experts say. There is no one solution for all.

“First, we as a society must consider obesity as a disease, as a biological problem, not as a moral failing,” Grunvald said. “That’s my first piece of advice.

“And if you believe your life is going to benefit from treatment, then consider evidence-based treatment, which studies show are surgery or medications, if you haven’t been able to successfully do it with lifestyle changes alone.”

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Business

FDA vaccine advisers vote to harmonize Covid-19 vaccines in the United States

January 27, 2023 Admin Leave a comment

CNN
—

A panel of independent experts that advises the US Food and Drug Administration on its vaccine decisions voted unanimously Thursday to update all Covid-19 vaccines so they contain the same ingredients as the two-strain shots that are now used as booster doses.

The vote means young children and others who haven’t been vaccinated may soon be eligible to receive two-strain vaccines that more closely match the circulating viruses as their primary series.

The FDA must sign off on the committee’s recommendation, which it is likely to do, before it goes into effect.

Currently, the US offers two types of Covid-19 vaccines. The first shots people get – also called the primary series – contain a single set of instructions that teach the immune system to fight off the original version of the virus, which emerged in 2019.

This index strain is no longer circulating. It was overrun months ago by an ever-evolving parade of new variants.

Last year, in consultation with its advisers, the FDA decided that it was time to update the vaccines. These two-strain, or bivalent, shots contain two sets of instructions; one set reminds the immune system about the original version of the coronavirus, and the second set teaches the immune system to recognize and fight off Omicron’s BA.4 and BA.5 subvariants, which emerged in the US last year.

People who have had their primary series – nearly 70% of all Americans – were advised to get the new two-strain booster late last year in an effort to upgrade their protection against the latest variants.

The advisory committee heard testimony and data suggesting that the complexity of having two types of Covid-19 vaccines and schedules for different age groups may be one of the reasons for low vaccine uptake in the US.

Currently, only about two-thirds of Americans have had the full primary series of shots. Only 15% of the population has gotten an updated bivalent booster.

Data presented to the committee shows that Covid-19 hospitalizations have been rising for children under the age of 2 over the past year, as Omicron and its many subvariants have circulated. Only 5% of this age group, which is eligible for Covid-19 vaccination at 6 months of age, has been fully vaccinated. Ninety percent of children under the age of 4 are still unvaccinated.

“The most concerning data point that I saw this whole day was that extremely low vaccination coverage in 6 months to 2 years of age and also 2 years to 4 years of age,” said Dr. Amanda Cohn, director of the US Centers for Disease Control and Prevention’s Division of Birth Defects and Infant Disorders. “We have to do much, much better.”

Cohn says that having a single vaccine against Covid-19 in the US for both primary and booster doses would go a long way toward making the process less complicated and would help get more children vaccinated.

Others feel that convenience is important but also stressed that data supported the switch.

“This isn’t only a convenience thing, to increase the number of people who are vaccinated, which I agree with my colleagues is extremely important for all the evidence that was related, but I also think moving towards the strains that are circulating is very important, so I would also say the science supports this move,” said Dr. Hayley Gans, a pediatric infectious disease specialist at Stanford University.

Many others on the committee were similarly satisfied after seeing new data on the vaccine effectiveness of the bivalent boosters, which are cutting the risk of getting sick, being hospitalized or dying from a Covid-19 infection.

“I’m totally convinced that the bivalent vaccine is beneficial as a primary series and as a booster series. Furthermore, the updated vaccine safety data are really encouraging so far,” said Dr. David Kim, director of the the US Department of Health and Human Services’ National Vaccine Program, in public discussion after the vote.

Thursday’s vote is part of a larger plan by the FDA to simplify and improve the way Covid-19 vaccines are given in the US.

The agency has proposed a plan to convene its vaccine advisers – called the Vaccines and Related Biological Products Advisory Committee, or VRBPAC – each year in May or June to assess whether the instructions in the Covid-19 vaccines should be changed to more closely match circulating strains of the virus.

The time frame was chosen to give manufacturers about three months to redesign their shots and get new doses to pharmacies in time for fall.

“The object, of course – before anyone says anything – is not to chase variants. None of us think that’s realistic,” said Jerry Weir, director of the Division of Viral Products in the FDA’s Office of Vaccines Research and Review.

“But I think our experience so far, with the bivalent vaccines that we have, does indicate that we can continue to make improvements to the vaccine, and that would be the goal of these meetings,” Weir said.

In discussions after the vote, committee members were supportive of this plan but pointed out many of the things we still don’t understand about Covid-19 and vaccination that are likely to complicate the task of updating the vaccines.

For example, we now seem to have Covid-19 surges in the summer as well as the winter, noted Dr. Michael Nelson, an allergist and immunologist at the University of Virginia. Are the surges related? And if so, is fall the best time to being a vaccination campaign?

The CDC’s Dr. Jefferson Jones said that with only three years of experience with the virus, it’s really too early to understand its seasonality.

Other important questions related to the durability of the mRNA vaccines and whether other platforms might offer longer protection.

“We can’t keep doing what we’re doing,” said Dr. Bruce Gellin, chief of global public health strategy at the Rockefeller Foundation. “It’s been articulated in every one of these meetings despite how good these vaccines are. We need better vaccines.”

The committee also encouraged both government and industry scientists to provide a fuller picture of how vaccination and infection affect immunity.

One of the main ways researchers measure the effectiveness of the vaccines is by looking at how much they increase front-line defenders called neutralizing antibodies.

Neutralizing antibodies are like firefighters that rush to the scene of an infection to contain it and put it out. They’re great in a crisis, but they tend to diminish in numbers over time if they’re not needed. Other components of the immune system like B-cells and T-cells hang on to the memory of a virus and stand ready to respond if the body encounters it again.

Scientists don’t understand much about how well Covid-19 vaccination boosts these responses and how long that protection lasts.

Another puzzle will be how to pick the strains that are in the vaccines.

The process of selecting strains for influenza vaccines is a global effort that relies on surveillance data from other countries. This works because influenza strains tend to become dominant and sweep around the world. But Covid-19 strains haven’t worked in quite the same way. Some that have driven large waves in other countries have barely made it into the US variant mix.

“Going forward, it is still challenging. Variants don’t sweep across the world quite as uniform, like they seem to with influenza,” the FDA’s Weir said. “But our primary responsibility is what’s best for the US market, and that’s where our focus will be.”

Eventually, the FDA hopes that Americans would be able to get an updated Covid-19 shot once a year, the same way they do for the flu. People who are unlikely to have an adequate response to a single dose of the vaccine – such as the elderly or those with a weakened immune system – may need more doses, as would people who are getting Covid-19 vaccines for the first time.

At Thursday’s meeting, the advisory committee also heard more about a safety signal flagged by a government surveillance system called the Vaccine Safety Datalink.

The CDC and the FDA reported January 13 that this system, which relies on health records from a network of large hospital systems in the US, had detected a potential safety issue with Pfizer’s bivalent boosters.

In this database, people 65 and older who got a Pfizer bivalent booster were slightly more likely to have a stroke caused by a blood clot within three weeks of their vaccination than people who had gotten a bivalent booster but were 22 to 42 days after their shot.

After a thorough review of other vaccine safety data in the US and in other countries that use Pfizer bivalent boosters, the agencies concluded that the stroke risk was probably a statistical fluke and said no changes to vaccination schedules were recommended.

At Thursday’s meeting, Dr. Nicola Klein, a senior research scientist with Kaiser Permanente of Northern California, explained how they found the signal.

The researchers compared people who’d gotten a vaccine within the past three weeks against people who were 22 to 42 days away from their shots because this helps eliminate bias in the data.

When they looked to see how many people had strokes around the time of their vaccination, they found an imbalance in the data.

Of 550,000 people over 65 who’d received a Pfizer bivalent booster, 130 had a stroke caused by a blood clot within three weeks of vaccination, compared with 92 people in the group farther out from their shots.

The researchers spotted the signal the week of November 27, and it continued for about seven weeks. The signal has diminished over time, falling from an almost two-fold risk in November to a 47% risk in early January, Klein said. In the past few days, it hasn’t been showing up at all.

Klein said they didn’t see the signal in any of the other age groups or with the group that got Moderna boosters. They also didn’t see a difference when they compared Pfizer-boosted seniors with those who were eligible for a bivalent booster but hadn’t gotten one.

Further analyses have suggested that the signal might be happening not because people who are within three weeks of a Pfizer booster are having more strokes, but because people who are within 22 to 42 days of their Pfizer boosters are actually having fewer strokes.

Overall, Klein said, they were seeing fewer strokes than expected in this population over that period of time, suggesting a statistical fluke.

Another interesting thing that popped out of this data, however, was a possible association between strokes and high-dose flu vaccination. Seniors who got both shots on the same day and were within three weeks of those shots had twice the rate of stroke compared with those who were 22 to 42 days away from their shots.

What’s more, Klein said, the researchers didn’t see the same association between stroke and time since vaccination in people who didn’t get their flu vaccine on the same day.

The total number of strokes in the population of people who got flu shots and Covid-19 boosters on the same day is small, however, which makes the association a shaky one.

“I don’t think that the evidence are sufficient to conclude that there’s an association there,” said Dr. Tom Shimabukuro, director of the CDC’s Immunization Safety Office.

Nonetheless, Richard Forshee, deputy director of the FDA’s Office of Biostatistics and Pharmacovigilance, said the FDA is planning to look at these safety questions further using data collected by Medicare.

The FDA confirmed that the agency is taking a closer look.

“The purpose of the study is 1) to evaluate the preliminary ischemic stroke signal reported by CDC using an independent data set and more robust epidemiological methods; and 2) to evaluate whether there is an elevated risk of ischemic stroke with the COVID-19 bivalent vaccine if it is given on the same day as a high-dose or adjuvanted seasonal influenza vaccine,” a spokesperson said in a statement.

The FDA did not give a time frame for when these studies might have results.

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Entertainment

Lisa Marie Presley’s memorial to be held at Graceland

January 17, 2023 Admin Leave a comment

CNN
—

Lisa Marie Presley’s cause of death has not yet been determined after an initial autopsy examination, according to the Los Angeles County Coroner.

“Presley was examined on Jan. 14 and the cause of death was deferred. Deferred means that after an autopsy, a cause of death has not been determined and the medical examiner is requesting more investigation into the death, including additional studies. Once the tests/studies come back, the doctor evaluates the case again and makes the cause of death determination,” Sarah Ardalani, spokesperson with the LA County Dept. of Medical Examiner-Coroner told CNN.

The singer and songwriter died last week after being hospitalized following an apparent cardiac arrest.

She was 54.

A public memorial for Presley has been planned at Graceland in Memphis, Tennessee on January 22, according to a statement on Graceland’s website.

“In lieu of flowers, the family encourages all who wish to send something to do so in the form of a donation to The Elvis Presley Charitable Foundation,” a notice on the site reads.

The Elvis Presley Charitable Foundation supports arts, education and efforts on behalf of children in the Memphis area.

Elvis Presley purchased the estate in 1957 when he was just 22 years old.

He died in the mansion from cardiac arrest in 1977 and is buried on the grounds of Graceland, which is now a museum and a popular tourist attraction. Lisa Marie Presley will be buried there as well, alongside her son Benjamin Keough, who died by suicide in 2020 at the age of 27.

The Graceland estate was held in trust for Lisa Marie Presley, the only child of Elvis and Priscilla Presley, until her 25th birthday.

“Lisa Marie Presley became more closely involved with the management team of The Elvis Presley Trust and its business entity, Elvis Presley Enterprises, Inc.(EPE), of which she was owner and Chairman of the Board until February 2005 when she sold a major interest in the company,” according to the Graceland website.

Over the weekend, grief expert David Kessler shared a photo of himself and Presley on his verified Instagram account, writing that she had asked him to accompany her to Memphis for an 88th birthday celebration for her late father days before her death.

“She had countless invites for the weekend, but for her, there were only three important ones: being at her father’s birthday celebration, spending time at her son and father’s grave after the tours left Graceland, and meeting with a recently bereaved mother,” Kessler wrote.

Presley was active in helping others deal with their grief, he wrote, including co-hosting grief groups with him at her home for other bereaved parents.

Kessler wrote that their time visiting Graceland was “so much fun and she was optimistic” and that “Graceland was her happy place and the employees who all knew her shared that she was looking so much better.”

“She looked more at peace and was so proud of the Elvis movie. Saturday night we sat at the graves of her father and son,” he wrote. “We talked about the heartbreak she grew up with and the more recent devastation of her son’s death. She showed me where she would be buried someday. I said a long time from now …and she said yes, I have so much to do.”

Presley is survived by her three daughters, actress Riley Keough and twins Finley and Harper Lockwood. A rep for Graceland confirmed to People that they will inherit the estate.

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Keenan Anderson, cousin of Black Lives Matter co-founder, dies from cardiac arrest after being tased by Los Angeles police

January 14, 2023 Admin Leave a comment

CNN
—

A 31-year-old father and English teacher died from cardiac arrest last week after he was repeatedly tased by police, according to the Los Angeles Police Department, marking the third officer-involved death in the city this year.

Police encountered Keenan Anderson, who is the cousin of Black Lives Matter co-founder Patrisse Cullors, on January 3 at the site of a traffic collision in Los Angeles’ Venice neighborhood, police said in a news release last week.

As police struggled to arrest Anderson, they tased him repeatedly, edited body-worn camera footage released by police shows. After being arrested, Anderson was brought to a local hospital, where he went into cardiac arrest and was pronounced dead, according to police.

Cullors said in an Instagram tribute post that her cousin was “killed by LAPD.”

“Keenan deserves to be alive right now, his child deserves to be raised by his father,” Cullors wrote in the post. “Keenan we will fight for you and for all of our loved ones impacted by state violence. I love you.”

Anderson taught tenth-grade English at Digital Pioneers Academy in Washington, DC, according to a statement from the school’s founder, Mashea Ashton. Anderson was visiting family in Los Angeles over winter break, Ashton said.

“The details of his death are as disturbing as they are tragic,” Ashton said in the statement, adding, “Keenan was a deeply committed educator and father of a six-year-old son. … He was beloved by all.”

“Our community is grieving. But we’re also angry. Angry that, once again, a known, loved, and respected member of our community is no longer with us. Angry that another talented, beautiful black soul is gone too soon,” Ashton said.

Detectives from the police department’s Force Investigation Division responded to the scene where Anderson was taken into custody and are investigating the use of force, police said, explaining in the video that the department’s policy defines any death of a person in their custody as a “categorical” use of force.

So far this year, Los Angeles police are also investigating the police shooting deaths of Takar Smith, 45, and Oscar Sanchez, 35, and has released footage of those incidents.

Police said they responded to a traffic collision the afternoon of January 3 and saw Anderson “running in the middle of the street and exhibiting erratic behavior.” On one officer’s body-worn camera, released and edited by police, a woman at the traffic collision site tells police, “I think that guy up there needs help though, because the guy’s trying to run away.”

Body-worn camera video shows Anderson initially stopped and spoke to an officer before the video cuts to a text screen that says Anderson “attempted to run away.”

When the video resumes, Anderson is seen jogging into the street as the officer pursues him and stops him in a busy intersection, commanding Anderson to lay down on his stomach.

Anderson does not appear to comply immediately, and two other officers arrive and move him to lie prone on his stomach on the street, telling Anderson to “relax.” As officers struggle on top of him, Anderson can be heard screaming, “Help, they’re trying to kill me” and “Please, don’t do this.”

In footage from another responding officer, an officer can be heard repeatedly warning Anderson to stop resisting and turn over, and threatening several times to tase Anderson.

“They’re trying to George Floyd me,” says Anderson, as officers try to roll him onto his stomach.

Then, an officer deploys a taser multiple times on Anderson, who says, “I’m not resisting.”

Officers eventually handcuff and place ankle hobbles on Anderson, the video shows.

Later in the video, the Los Angeles Fire Department places Anderson, who appears conscious, onto a gurney near an ambulance. Police say in the news release that Anderson was given medical care at the scene by fire department personnel before being transported to a local hospital.

“While at the hospital, Anderson went into cardiac arrest and was pronounced deceased,” the release says.

Los Angeles police captain Kelly Muñiz said in the video that Anderson died approximately four-and-a-half hours after the use of force.

A preliminary toxicology-blood screen of Anderson’s blood samples tested positive for cocaine and marijuana, police said, adding the Los Angeles County coroner’s office is expected to conduct their own independent toxicology tests.

LAPD Chief Michel Moore said the videos were published in response to calls for their release from families.

“This is not, again, to do anything other than to demonstrate our commitment to full transparency and to judge this on the merits of what the investigation shows us and to ask for the public’s patience as we go about this engagement,” he said at a news conference Wednesday.

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Business

CDC identifies possible safety issue with Pfizer’s updated Covid-19 vaccine but says people should still get boosted

January 13, 2023 Admin Leave a comment

CNN
—

The US Centers for Disease Control and Prevention said Friday that there is a possible safety issue with the bivalent Covid-19 vaccine made by Pfizer and BioNTech but that it is unlikely to represent a true risk. The agency said it continues to recommend that people stay up-to-date with Covid-19 vaccines.

The CDC said one of its vaccine safety monitoring systems – a “near real-time surveillance system” called the Vaccine Safety Datalink – detected a possible increase in a certain kind of stroke in people 65 and older who recently got one of Pfizer’s updated booster shots.

A rapid response analysis of that signal revealed that seniors who got an bivalent booster might be more likely to have ischemic strokes within the first three weeks after their shots, compared with weeks four through six.

Ischemic strokes, the most common form, are blockages of blood to the brain. They’re usually caused by clots.

The Vaccine Safety Datalink, or VSD, is a network of large health systems across the nation that provides data about the safety and efficacy of vaccines through patients’ electronic health records. The CDC said it had identified possible confounding factors in the data coming from the VSD that may be biasing the data and need further investigation.

Of about 550,000 seniors who got Pfizer bivalent boosters and were tracked by the VSD, 130 had strokes in the three weeks after the shot, according to a CDC official who spoke to CNN on condition of anonymity because they weren’t authorized to share the data. None of the 130 people died.

The number of strokes detected is relatively small, said Dr. William Schaffner, an infectious disease expert at Vanderbilt University and a member of the CDC Advisory Committee on Immunization Practices’ Covid-19 Vaccine Work Group.

“These strokes are not a confirmed adverse event at the moment,” he said. “It’s like a radar system. You’re getting a blip on the radar, and you have to do further investigation to discover whether that airplane is friend or foe.”

The same safety signal has not been detected with the bivalent Moderna booster, the CDC said in its notice.

The agency noted that it has looked for and failed to find the same increase in strokes in other large collections of medical records, including those maintained by Medicare, the US Department of Veterans Affairs, as well as its Vaccine Adverse Event Reporting System, known as VAERS.

Neither Pfizer nor other countries that are using the vaccine have seen any increase in this kind of stroke, the agency said, and the signal was not detected in any other databases.

The CDC says that it does not recommend any change to vaccination practices at this time and that the risks of Covid-19 for older adults continue to outweigh any possible safety issues with the vaccine.

“Although the totality of the data currently suggests that it is very unlikely that the signal in VSD represents a true clinical risk, we believe it is important to share this information with the public, as we have in the past, when one of our safety monitoring systems detects a signal,” the notice says.

“CDC and FDA will continue to evaluate additional data from these and other vaccine safety systems. These data and additional analyses will be discussed at the upcoming January 26 meeting of the FDA’s Vaccines and Related Biological Products Advisory Committee.”

Pfizer said in a statement Friday, “Neither Pfizer and BioNTech nor the CDC or the U.S. Food and Drug Administration (FDA) have observed similar findings across numerous other monitoring systems in the U.S. and globally and there is no evidence to conclude that ischemic stroke is associated with the use of the companies’ COVID-19 vaccines.

“Compared to published incidence rates of ischemic stroke in this older population, the companies to date have observed a lower number of reported ischemic strokes following the vaccination with the Omicron BA.4/BA.5-adapted bivalent vaccine.”

The bivalent boosters from Pfizer/BioNTech and Moderna protect against the original strain of the coronavirus as well as the Omicron BA.4 and BA.5 subvariants. Only about 50 million Americans ages 5 and up have gotten them since they were authorized last fall, according to CDC data.

Schaffner said he was part of a briefing Thursday with members of the Covid-19 Vaccine Work Group. He couldn’t share specific details about the briefing but said the safety signal was discussed.

His biggest takeaway was that the safety surveillance system is working.

It’s very likely that this is a false signal, he said, but it’s being investigated, which is important.

“You want a surveillance system that occasionally sends up false signals. If you don’t get any signals, you’re worried that you’re missing stuff.”

Schaffner said he would absolutely tell people to get their Covid-19 booster if they haven’t done so yet – even those 65 and older.

“Undoubtedly, the risk of a whole series of adverse events, including hospitalization, is much, much greater with Covid-19 than it is from the vaccine,” he said.

He also said the signal – if real – may be more a factor of numbers than an indication that one manufacturer’s vaccine is riskier than the other.

Nearly two-thirds of the people in the US who’ve gotten an updated booster – 32 million – have gotten Pfizer, compared with about 18 million Moderna shots.

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Damar Hamlin could be released from a Buffalo hospital in the next day or two

January 10, 2023 Admin Leave a comment

CNN
—

A week after suffering a cardiac arrest while playing the Cincinnati Bengals, Buffalo Bills safety Damar Hamlin appears to be healthy enough to be released from a Buffalo hospital within 24 to 48 hours, Michael Hughes, senior vice president and chief administrative officer at Kaleida Health, told CNN on Tuesday.

Doctors are finishing tests on Hamlin and are optimistic they will be able to determine whether there were any pre-existing conditions that played a role in Hamlin’s cardiac arrest January 2. The hospital plans to release a written health update on Tuesday.

If doctors’ early findings hold true, Hughes said the injury was strictly caused by blunt force trauma.

Hamlin was transferred from a Cincinnati hospital to the Buffalo hospital on Monday after doctors determined his critical condition had improved to good or fair – surpassing expectations.

“We felt that it was safe and proper to help get him back to the greater Buffalo area,” Dr. Timothy Pritts, chief of surgery at the University of Cincinnati Medical Center, said Monday.

Hamlin’s parents flew from Cincinnati back home to Pittsburgh but then flew to Buffalo. They were en route Tuesday from the Buffalo Bills’ practice facility and were expected to arrive at the hospital to see Hamlin soon.

Hamlin, a second-year NFL player, has been regaining strength over the past several days after his sudden collapse after a tackle against the Bengals in Cincinnati.

“He’s certainly on what we consider a very normal to even accelerated trajectory from the life-threatening event that he underwent,” Pritts said, “but he’s making great progress.”

Normal recovery from a cardiac arrest can be measured in weeks to months, Pritts explained. But Hamlin has been beating that timeline at each stage and is neurologically intact.

Still, Pritts said it’s too early to say when Hamlin could get back to normal life or what caused his heart to stop, saying more testing is needed.

Hamlin was sedated and on a ventilator for days after his cardiac arrest. On Friday morning, the breathing tube was removed, and Hamlin began walking with some help by that afternoon, his doctors said Monday.

The safety’s condition was upgraded Monday because his organ systems were stable and he no longer needed intensive nursing or respiratory therapy, doctors said.

“He walks normally,” said Dr. William Knight, a neurovascular critical care expert who treated Hamlin at UC Health. “He is admittedly a little weak. I don’t think that’s of any real surprise after what he went through, just regaining his strength. And that’s part of his recovery process.”

Hamlin’s release Monday meant he could return to Buffalo, which prompted even more encouragement and eagerness for some of his teammates to see him again.

“Super excited that he’s back in Buffalo and what a job that the team of docs and the medical team did out in Cincinnati, and now he’s in great care here in Buffalo. We’re happy to have him back,” Buffalo Bills head coach Sean McDermott told reporters Monday.

After seeing him Monday, McDermott said Hamlin was “tired” but seemed happy. “Happy to be back in Buffalo and around a familiar area to him. I know he’s taking it just one step at a time.”

The coach also said his team has grown since Hamlin was injured, saying such experiences nurture growth.

“We will all have grown as people, and as men in this case,” McDermott said, noting there’s a plan in place for the players and staff to visit Hamlin “at the proper time.”

“Having him nearby will give us more comfort” and inspire the team as it prepares for the postseason, McDermott said.

Although Hamlin was not with the team when they played Sunday against the New England Patriots, his support was definitely felt.

When his team scored a touchdown, Hamlin set off alarms in the ICU, Pritts said.

“When the opening kickoff was run back, he jumped up and down and got out of his chair and set – I think – every alarm off in the ICU in the process, but he was fine, it was just an appropriate reaction to a very exciting play. He very much enjoyed it,” Pritts said.

Hamlin was “beyond excited” Sunday and felt “very supported by the outpouring of love from across the league, especially from the Buffalo area. We’ve learned this week that the Bills mafia is a very real thing,” Pritts added.

The immediate medical response to Hamlin’s collapse helped save his life, and the Buffalo Bills are now encouraging people to learn how to administer CPR.

Assistant athletic trainer Denny Kellington is credited with performing CPR when Hamlin lost his pulse on the field and needed to be revived through resuscitation and defibrillation.

The medical response was part of an emergency action plan that “involves team, independent medical and athletic training staff, equipment and security personnel, and is reviewed prior to every game,” a Monday statement from the Bills read.

The team pledged support for resources including CPR certifications, automated external defibrillator units and guidance developing cardiac emergency response plans within the Buffalo community, according to the statement.

“We encourage all our fans to continue showing your support and take the next step by obtaining CPR certification,” the Bills said.

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Damar Hamlin tweets his thanks after he moves from Cincinnati to Buffalo hospital 7 days after collapse

January 9, 2023 Admin Leave a comment

CNN
—

Damar Hamlin was released from the hospital on Monday, a week after the Buffalo Bills safety’s heart stopped and he had to be resuscitated on the field during an NFL game, Dr. William A. Knight said Monday during a video news conference.

Knight said he went with Hamlin to the airport, where he took a flight to Buffalo. Hamlin is in a hospital there, the doctor from the UC Medical Center in Cincinnati said.

“He is doing well and this is the beginning of the next stage of his recovery,” Knight said. “It is entirely too premature to discuss, not only his football; it’s that we’re really focused on his day-to-day recovery.”

Knight said Hamlin met “a number of key milestones” in his recovery, noting the NFL player was up and walking, doing physical and occupational therapy.

“Grateful for the awesome care I received at UCMC. Happy to be back in Buffalo. The docs and nurses at Buffalo General have already made me feel at home!” Hamlin tweeted Monday afternoon.

In another tweet, he thanked the public for their support.

“Watching the world come together around me on Sunday was truly an amazing feeling,” he wrote. “The same love you all have shown me is the same love that I plan to put back into the world n more. Bigger than football!”

Bills head coach Sean McDermott said on a Zoom call with reporters that he was “super excited” to have Hamlin back in town.

He said he and some members of the Bills’ organization went to see Hamlin at the hospital in Buffalo.

“He’s doing well,” he said. “He’s just tired but he seems happy and happy to be back in Buffalo.”

On January 2, Hamlin, a 24-year-old defensive player in his second NFL season, suffered a cardiac arrest and collapsed during a game against the Cincinnati Bengals.

His UC doctors said Monday it’s still too early to know what caused Hamlin’s cardiac arrest and expect he will undergo more tests to determine what happened.

The Bills player on Sunday posted a photo of himself on social media that shows him sitting up in his hospital bed and making a heart sign with his hands while wearing a number 3 hat and a “Love for Damar” shirt.

Hamlin tweeted more than a dozen times reacting to the Bills 35-22 win over the New England Patriots Sunday, and expressed his desire to be out on the field with his teammates.

“It’s GameDay & There’s Nothing I Want More Than To Be Running Out That Tunnel With My Brothers,” he wrote.

Hamlin also watched from his hospital bed Sunday as teams across the NFL honored him during the last games of the regular season, with players, coaches and fans expressing their support with T-shirts, signs and jersey patches featuring his name and his number 3.

At the Bills’ Highmark Stadium in Orchard Park, several of Hamlin’s teammates took the field waving flags with his name and jersey number while many in the audience raised heart-shaped signs to pay tribute to the football player.

The day before, the Bills tweeted that Hamlin continues to breathe on his own and his neurological function is excellent, but he was still in critical condition, citing his doctors.

Hamlin collapsed after making a tackle during the first quarter of the Bills’ game against the Cincinnati Bengals last Monday night. He was rushed from the field in an ambulance, leaving players crying and embracing, and unleashing an outpouring of support from fans and others across the country.

The game was initially postponed, then later canceled by the NFL.

Before Sunday’s game between the Baltimore Ravens and the Bengals, the medical staff who rushed to Hamlin’s aid were honored at Cincinnati’s Paycor Stadium – the same field where Hamlin suffered the cardiac arrest.

At New York’s Highmark Stadium, Buffalo Bills wide receiver John Brown gave a game ball to assistant athletic trainer Denny Kellington, the man credited with saving Hamlin’s life by administering critical CPR to the football player – who doctors say lost his pulse on the field had to be immediately revived through resuscitation and defibrillation.

The immediate response of Kellington and other medical personnel was vital to “not just saving his life, but his neurological function,” Dr. Timothy Pritts, one of Hamlin’s doctors at the University of Cincinnati Medical Center, has said.

Hamlin was sedated after being taken to the hospital. Doctors announced Thursday that he had started to awaken and he appears neurologically intact, while still critically ill and on a ventilator.

“Did we win?” was Hamlin’s first question upon awakening, according to Pritts, who said he scribbled the question on a clipboard.

On Friday, the Bills said Hamlin’s breathing tube was removed overnight and he had spoken to his teammates via video.

Following the victory over the Patriots on Sunday, Bills cornerback Tre’Davious White said Hamlin texted members of the team prior to Sunday’s game, saying, “I’m thinking about y’all, I’m sorry that I did that to y’all.”

“For him to check on us when he is the person that’s going through what he’s going through – that just shows what type of person he is.”

White said incident Monday’s incident still haunts the six-year NFL veteran.

“To see everything transpire, from the hit, to him getting up, to him falling, to everything – it’s just something that I can’t … unsee. Every time I close my eyes it replays. I tried watching tv and every time the tv goes to commercial, that’s the only thing that comes to my mind,” White said.

During Sunday’s Bills game, the public address announcer read a statement of support for Hamlin and received a roar from the crowd, which included fans in a sea of blue and red who held up signs of support for Hamlin saying “BILLI3VE,” “All the heart for #3,” “Love for Damar,” “Did we win” and “Thank You Medical Staff!”

Several of Hamlin’s teammates, including Josh Allen and Kaiir Elam, took the field waving flags with Hamlin’s name and jersey No. 3.

Then the game began with a bang.

Bills returner Nyhiem Hines took the opening kickoff for a 96-yard touchdown, sending the crowd into euphoria and prompted Hamlin to tweet, “OMFG!!!!!!!!!!!!!”

Hines said the team needed this win after the events of the past week.

“As a community, I feel like we needed this win. I feel like my brothers in that locker room, we needed some great energy and some great vibes. And we had to win this,” Hines said.

Other teams around the league also paid tribute to Hamlin Sunday.

In Cincinnati, Bengals wide receiver Tee Higgins, who was involved in the play where Hamlin was injured, wore a “Love for Damar” t-shirt during pregame warmups.

Prior to the start of the game, the stadium’s announcer read a statement that asked fans for a moment of support for Hamlin, his family and the first responders.

The fans in Cincinnati, many with signs supporting Hamlin, cheered loudly. The television broadcast also showed Bengals coach Zac Taylor wearing a “Love for Damar” hoodie during the tribute.

Ahead of the Chargers-Broncos game, Broncos Quarterback Russell Wilson and Chargers safety Derwin James met at midfield, both wearing No. 3, and led a moment of support for Hamlin.

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Buffalo Bills safety Damar Hamlin released from hospital 7 days after collapse

January 9, 2023 Admin Leave a comment

CNN
—

Knight said he went with Hamlin to the airport, where he took a flight to Buffalo. Hamlin is in a hospital there, the doctor from the UC Medical Center in Cincinnati said.

On January 2, Hamlin, a 24-year-old in his second NFL season, suffered a cardiac arrest and collapsed during a game against the Cincinnati Bengals.

The NFL star on Sunday posted a photo of himself on social media that shows him sitting up in his hospital bed and making a heart sign with his hands while wearing a number 3 hat and a “Love for Damar” shirt.