Category Archives: Health

How to get a covid-19 vaccine appointment for your child

Pfizer began packing up pediatric doses to be distributed shortly after, with the company saying 11 million doses are expected to go out in the first 10 days — but some families may not know the best way to get a vaccination for their children.

The first step is to call your pediatrician’s office and see when their next appointment is available, Dr. Leana Wen, a CNN medical analyst, said.

If the wait time is just a matter of days, Wen said she would wait and take the appointment. For those who are booked for weeks, it may be best to get on a waitlist with the physician and look for other options.

Chain and local pharmacies can be the next stop, recommended Wen, who is also an emergency physician and professor of health policy and management at the George Washington University Milken Institute School of Public Health.

“Make sure to mention your child’s exact age, as some places may not give shots to young kids. If they are not sure yet, call back the next day — a lot is changing very quickly,” she said.

Walgreens announced its pharmacies will begin administering pediatric Covid-19 vaccines across the nation beginning Saturday. Parents and guardians are able to make appointments on the website for the first vaccine dose shipments, and more appointments will become available as more shipments arrive, the company said in a news release.

Local health departments may also be able to provide information on vaccine clinics, Wen added.

More than half of US states do not specify that their vaccinations are for residents only, meaning if you have trouble securing an appointment locally, you may be able to be vaccinated in a nearby state.

Families should get kids vaccinated as soon as possible, experts say

The recommendation of the vaccine to children should be a cause for celebration, but it’s understandable if parents still have questions, CDC Director Dr. Rochelle Walensky said on ABC’s “Good Morning America” Wednesday.

“We are now beginning to roll out, to distribute the vaccine, to give parents the information that they need,” she said. “Go talk to your pediatrician, your trusted health care provider, your pharmacist and get the information that you need as we start scaling up vaccine across this country.”

The US has been preparing for children to become eligible for the vaccine, and Dr. Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases, told CNN’s Brianna Keilar on New Day Wednesday that officials plan to make doses available quickly.

“That was what the preparedness was about,” Fauci said. “It’s a good thing. We’ll hit the ground running and probably by the beginning of next week, we’ll be at full speed.”

Children won’t have the chance to be fully vaccinated — which is two weeks after their second dose — by Thanksgiving or Hanukkah, but with a first appointment by November 19, they can have full protection for Christmas, Kwanzaa and end-of-year gatherings.

If families and friends are getting together indoors for the holidays, it is crucial that children who can be vaccinated are, Wen said.

“There is a common, but very false, narrative out there that somehow children are not susceptible to severe outcomes from Covid-19, which is just not true,” Wen said. “Understandably, parents want to protect their children.”

CNN’s Naomi Thomas contributed to this report.

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Moderna Stock Plunges as Vaccine Sales, Earnings, Miss Forecasts

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Vials of the Moderna Covid-19 vaccine.


Guillaume Souvant/AFP via Getty Images


Moderna

shares plunged 12.3% in premarket trading on Thursday after sales of the company’s Covid-19 vaccine fell short of Wall Street analysts’ estimates by more than a billion dollars.

The company reported total revenue of $5 billion for the third quarter of the year, 20% short of the FactSet analyst consensus estimate of $6.2 billion. Spikevax,


Moderna

‘s (ticker: MRNA) Covid-19 vaccine, is the company’s only product.

The report comes two days after


Pfizer

(PFE) said it had sold $13 billion of its Covid-19 vaccine in the third quarter, blowing past the $10.9 billion FactSet analyst consensus estimate.

Moderna’s third-quarter disappointment further cements


Pfizer

‘s place as the dominant player in the Covid-19 vaccine market in the U.S. and Europe. Pfizer said Tuesday that its share of the Covid-19 vaccine market in the U.S. is now 75%, up from 56% in April.

Pfizer has snapped up the first authorizations for Covid-19 booster shots, and the vaccination of teenagers and of children. While Moderna’s booster is now authorized, Pfizer’s remains the only vaccine available in the U.S. for people under 18.

“We will not rest until our vaccine is available to anyone who needs it, and we are working hard to ensure our vaccine is available in low-income countries with approximately 10% of our 2021 volume and significantly more of our 2022 volume going to low-income countries,” said Moderna’s CEO, Stéphane Bancel, in a statement. “It is promising to see the real-world evidence showing that the Moderna COVID-19 vaccine shows sustainably high, durable efficacy.”

Moderna reported diluted earnings of $7.70 per share, well short of the S&P Capital IQ Consensus estimate of $9.42. The company reported net income of $3.3 billion.

Moderna now expects sales of between $15 billion and $18 billion this year, down from its previous estimate of $20 billion. The company attributed the drop to some deliveries being shifted to early 2022, and to “prioritization of deliveries to low-income countries.” It said it plans to deliver between 700 million and 800 million Covid-19 vaccine doses this year.

Moderna shares were up 231.1% so far this year as of the close of the market on Wednesday, and 383.9% over the past 12 months.

The company highlighted its deep bench of pipeline programs in its earnings release, though investor focus will likely be on the shortfalls on the top and bottom lines.

Moderna said it has signed $17 billion worth of purchase agreements for delivery of its Covid-19 vaccine in 2022. It also said it expects booster sales of up to $2 billion on the commercial market next fall. So far, all Covid-19 vaccine sales have been to governments; there is currently no Covid-19 vaccine commercial market.

The company said it expects 2022 sales of between $17 billion and $22 billion, in line with the FactSet consensus estimate of $21.4 billion.

Also on Thursday, Moderna announced that the Food and Drug Administration had granted priority review status for its application for full approval for Spikevax under an FDA program that accelerates the review of an application. The company said the FDA will aim to decide on full approval for the vaccine by April.

Moderna also announced initial data from a Phase 2/3 study of the Covid-19 vaccine in children aged 6 to 11. The company said that two weeks after a single dose of the vaccine, efficacy against symptomatic disease was 100%, while efficacy against asymptomatic infection was 65%. Details on the data were scant.

On Tuesday, the Centers for Disease Control and Prevention recommended a pediatric formulation of Pfizer’s vaccine for use in children aged 6 to 11, initiating a rollout that will be fully under way next week. Moderna’s vaccine remains available only to adults aged 18 and above.

On Sunday, company said that the FDA had told it Friday that it needs more time to assess its application for emergency use authorization for its Covid-19 vaccine in teenagers aged 12 to 17, as it evaluated new data on the risk of myocarditis after vaccination with messenger RNA-based vaccines.

The FDA review of myocarditis data won’t be complete before January, Moderna said.

A conference call for investors is scheduled for 8 a.m. Eastern time.

Write to Josh Nathan-Kazis at josh.nathan-kazis@barrons.com

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Apple cider vinegar for weight loss? Do the pills actually work?

There is no magic bullet for weight loss.

My main job as an emergency physician is to rule out life-threatening causes of what brings people to the ER. But I value those rare opportunities during a quiet shift to talk with patients about proven dietary or exercise regimens they could adopt to improve their overall health.

A lot of my patients don’t have a primary care doctor, can’t get an appointment or lost their job and health insurance during the pandemic; their ER visit is one of the few times they can ask a doctor their burning lifestyle questions.  

Recently, a patient asked me about apple cider vinegar pills. He’d read on the Internet that they help with weight loss. Apple cider vinegar is proven to control blood sugar spikes in some type 2 diabetics and reduce LDL cholesterol. But does the science support it as a weight loss method?

Apple cider vinegar is made from apples that have been processed, distilled and fermented. Acetic acid is the active ingredient in apple cider vinegar (as in all vinegars) and is likely the driver of any health benefits. But its acidic nature and high potential for damage to tooth enamel and GI tract lining if consumed undiluted in large quantities likely limits both research studies and widespread use. This has not stopped supplement manufacturers from packaging it into pills, perhaps to make it more palatable to consumers.

People are putting garlic in their ears. Doctor explains why it’s a bad idea.

Scientific studies on apple cider vinegar’s ability to help with weight loss are limited. In one small study, 39 participants who took 2 tablespoons of apple cider vinegar daily lost 3-4 pounds at the end of 12 months. In a larger study of 175 overweight participants who were given 2 tablespoons of regular vinegar daily, researchers observed a similar weight loss of 2-4 pounds. While significant, such meager results pale in comparison to other proven diets, exercise and weight loss programs.

Anecdotally, some patients report that including a tablespoon of diluted apple cider vinegar in their diet makes them feel fuller faster and reduces snack cravings between dinner and bedtime. A small study claimed that the level of satiety (feeling full) was related to amount of acetic acid consumed. So perhaps apple cider vinegar helps with weight loss through appetite suppression? But until we have more solid research, the jury is out.

Certainly, other vinegars like balsamic and wine vinegars have long been an important part of the Mediterranean diet. In addition to helping diabetics avoid post-meal sugar spikes, one of the best studied benefits of vinegar is its anti-oxidant ability to control or lower LDL cholesterol. If your doctor advises adding vinegar to your diet, try using it safely in a dressing for salads, for example, and be sure to dilute it to 3 parts olive oil to 1 part vinegar.

The Blue Zones diet: How to eat like people who live the longest

A nutritious diet with daily exercise remains the cornerstone of a scientifically proven weight loss program. It’s certainly not as easy as popping a pill, but the rewards start immediately and pay dividends for your health for years.

And if you are looking for an alternative to cardio, consider strength training like weightlifting to help you burn that unwanted fat. Compared to the scant scientific data on apple cider vinegar, consider a recent analysis of 58 studies totaling 3,000 research participants who were followed in strength training programs for an average of five months. Researchers found that on average, participants lost 1.4% of their total body fat, a much more significant and desirable result for those looking to lose weight.

And remember: There is magic pill for healthy weight loss. Be skeptical of any claim otherwise

More: Jump into a new fitness routine with a mini trampoline

Michael Daignault, MD, is a board-certified ER doctor in Los Angeles. He studied Global Health at Georgetown University and has a Medical Degree from Ben-Gurion University. He completed his residency training in emergency medicine at Lincoln Medical Center in the South Bronx. He is also a former United States Peace Corps Volunteer. 

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How Covid invades the brain: Dealing with long-term coronavirus

Early research suggests that SARS-CoV-2 can enter the brain easily through a person’s nose, infiltrating brain cells where it lurks unchecked, possibly leading to lasting neurological symptoms, such as trouble with thinking and memory.

Two new studies — from the California National Primate Research Center and the Rotman Research Institute in Toronto — suggest that the virus directly infects neurons in the brain, potentially offering clues as to why some people suffer from a range of symptoms long after their initial Covid infection.

Neither of the studies, presented Wednesday during a meeting of the Society for Neuroscience, has been peer-reviewed, and neither is expected to answer all questions surrounding long Covid.

But they come as researchers worldwide are urgently trying to learn more about the mysterious and debilitating illness that is estimated to affect at least one-third of the more than 46 million people who have been infected in the U.S., as well as millions more globally.

Full coverage of the Covid-19 pandemic

Zeroing in on how the virus invades and affects the brain has the potential to defog the window into long Covid, an illness that doctors so far have been unable to appropriately define, diagnose or treat.

“We’re still in the phase where it doesn’t even have a name. That’s a problem,” said Dr. Nir Goldstein, director of the Center for Post Covid Care and Recovery at National Jewish Health in Denver. Goldstein was not involved with the new research.

Invading the brain

The body’s natural blood-brain barrier usually does a good job at halting things like viruses before they can cross into the brain, though it is possible for viruses to sneak through. SARS-CoV-2 can do this, as well as other viruses, such as viral encephalitis and HIV. When those breaches occur, immune cells in the brain work to attack the invader.

But one of the new studies presented Wednesday suggests it is increasingly clear that SARS-CoV-2 can also take a different, less-guarded route through the nose, heading straight to the brain.

That research, from the California National Primate Research Center, found that rhesus monkeys infected with the virus had significant evidence of infection inside the brain’s neurons just seven days after exposure. This was particularly true for older, diabetic animals.

Proof that neurons can be infected would be a key finding. Such brain cells send information from the brain to other parts of the body via electrical impulses. Because neurons are so critical to normal function of the body, the immune system doesn’t want to attack even those that are diseased.

The virus, having hitched a ride on neurons, is then free to move about the brain’s circuitry.

“This, I believe, is a much more dangerous kind of infection,” said John Morrison, who led the research and is a professor of neurology at the University of California, Davis. If the virus can travel the brain’s circuitry, he said, “it can get to multiple brain regions that mediate things like cognition and memory, and emotion and mood.”

Those are precisely the issues reported so often among people with long Covid.

Previous research on neural infection has been mixed, and not all experts agree that the findings offer definitive proof.

During a media briefing at Wednesday’s meeting, Dr. Walter Koroshetz, director of the National Institute of Neurological Disorders and Stroke, said he remained unconvinced that SARS-CoV-2 can infect neurons, adding that much more research is necessary.

Dr. Greg Vanichkachorn, an occupational medicine specialist who works with long Covid patients at the Mayo Clinic in Rochester, Minnesota, said brain samples taken from people who died of Covid-19 earlier in the pandemic largely haven’t shown this kind of infection.

But, he added, it is possible that Covid-19 affected those patients in a different way. Indeed, not all patients develop the same kind of illness. And it may turn out that people with less severe illness, albeit one that smolders on for months, are infected differently.

“I have always felt from from very early on in treating patients with this condition that it’s more than just a respiratory condition,” Vanichkachorn, who had no role in the new research, said. “I am not surprised about these findings.”

It’s not all in their heads

Another study presented at Wednesday’s meeting, provided additional evidence of neural infection. Researchers at the Rotman Research Institute in Toronto used electroencephalography, or EEG, to measure how well the brain is functioning in terms of its electrical signals.

The study was small, just 41 Covid-positive patients and 14 others who had some symptoms, but ultimately tested negative. All had mild illnesses and were never hospitalized.

The EEGs showed different brain wave patterns in the Covid patients that lasted at least seven months following their initial infection.

Put simply, their brains weren’t working as efficiently or as effectively, on average, compared to those who did not have Covid, said Allison Sekuler, who led the research and also serves as the Institute’s Sandra A. Rotman Chair in Cognitive Neuroscience.

Download the NBC News app for full coverage of the Covid-19 pandemic

Sekuler’s research, too, should be considered early and preliminary. And it is unlikely that the new findings can fully explain the types of brain fog and other cognitive issues reported by those with long Covid.

But Sekuler said the results so far “clearly show” monthslong changes in brain function. If proven in future analyses, the findings could offer reassurance to long-haulers whose loved ones may be skeptical about ongoing, ambiguous symptoms.

“It is very frustrating for many of my patients” who say they have family members who don’t believe that Covid exists in the first place, Vanichkachorn said. “Patients often get accused of malingering or making this all up for attention.”

Sekuler also dismissed those who claim long Covid symptoms are “just all in a person’s head.”

“Yeah, OK, but that’s because the brain controls everything,” she said, “your sense of smell, your memory, the way you see the world, even the way you feel.”

Follow NBC HEALTH on Twitter & Facebook.



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San Francisco to force five-year-olds to show proof of vaccination to enter indoor venues

Children aged five to 11 will be forced to prove they are vaccinated if they want to enter restaurants and entertainment venues in San Francisco, officials have said.

The progressive city became the first in the country to impose strict vaccine mandates for indoor venues in August for all children and adults over 12.

Now, City officials plan to extend such requirements to children as young as five and made the announcement at a town hall meeting Tuesday, the same day the CDC granted emergency approval for that age group to receive the Pfizer-BioNTech shot.

However, the CDC’s decision to approve the vaccine for the five to 11 age group has caused a storm of controversy nationwide, with opponents pointing to the fact there is little evidence to suggest vaccinating young children is necessary.

Data shows Covid poses a low risk to the age group, with children accounting for less than 0.1 percent of the more than 750,000 Covid-related deaths in America.

The decision means the US becomes one of the first countries in the world to officially approve jabs for this age group, with scientists in Britain warning officials against ‘blindly’ following America and recommending the jab to young children.

There have been more than 1.9 million cases of Covid-19 among five- to 11-year-olds in the United States, and more than 8,300 hospitalizations, more than 2,300 cases of MIS-C (pediatric multisystem inflammatory syndrome), and about 100 deaths.

Polls suggest many parents are not likely to have their kids vaccinated, with one poll finding around a third would ‘definitely not’.

A further third said in the poll they would ‘wait and see’ and five percent said they would ‘only if required’. Meanwhile, just 27 percent of parents questioned said they would get their children vaccinated ‘right away’.

San Francisco Health Officer Susan Philip said the city would give children roughly two months to get fully vaccinated before they must show their vaccination passports or be turned away from local establishments.

San Francisco plans to mandate children aged 5 to 11 show proof of vaccination to enter indoor venues. San Francisco Health Officer Susan Philip made the announcement at a town hall meeting via Zoom on Tuesday

City officials made the announcement the same day the CDC granted emergency approval of the PFizer-BioNTech for that age group. Above, a child received the shot Wednesday in Los Angeles

‘We definitely want to wait and make sure children have an opportunity to get vaccinated, so that will happen no sooner than about eight weeks after the vaccine is available to kids, so there will be a limited time in which there will not be those requirements in our plan,’ she said. 

‘But at some point, five to 11 year olds will also have to show proof of vaccination to access some of those same settings.’

Vaccinations for children in that age group started in California the day after the CDC’s Advisory Committee on Immunization Practices unanimously voted 14-0 to recommend the pediatric vaccine.

CDC director Dr Rochelle Walensky then signed off on the vote, meaning that approximately 28 million children in the US are now eligible for the shots.

It was the final step in the process that will allow injections in young children to begin this week in the United States, with President Joe Biden issuing a statement calling the decision ‘a turning point’ in the battle against Covid-19 and said they had secured enough vaccines for every child in America.

Children who are vaccinated are given a third of the dose that adults receive and, like the adult inoculation, make two appointments 21 days apart.

The lower dose was chosen to minimize side effects and still produce strong immunity, Pfizer says, with studies showing that it is about 91 per cent effective against Covid.

Children who are vaccinated are given a third of the dose that adults receive. Above, a child was vaccinated Wednesday in Los Angeles

Officials from the San Francisco Department of Public Health on Wednesday confirmed the plan and noted that children wouldn’t be required to show a valid form of ID.

‘As with children 12-17 who may not have personal identification, we will follow the same approach with the younger kids such that they would not be penalized for not having an ID,’ a spokesperson from the department wrote in an email to Politico.

San Francisco’s requirement for children would be the first of its kind and the city does not require children to show proof of vaccination to enter school buildings.

The Los Angeles Unified School District, which requires children 12 and up to be vaccinated, announced this week that it does not intend to include children aged five to 11 in its school vaccine mandate just yet.

Governor Gavin Newsom’s planned vaccine mandate for children in schools will not take effect until the FDA grants full approval for each age group. 

Bernadette Rosselli, a local mother, told Fox News that the mandate was ‘absolutely ridiculous.’

She said, ‘Parents are concerned and rightly so. I think that it’s important that we take the time to make sure that it’s gonna be safe, especially when they’re at such a low rate of risk. It’s really not necessary to rush into this. Let’s give it a little time.’

Many parents have been undecided on vaccinating their children because kids rarely get severely ill and make up less than 0.1 percent of all Covid deaths in the U.S., according to the CDC. 

Dr. Houman Hemmati noted the low infection rates in an interview with Fox News and said, ‘With vaccines, as with any drug, there’s a calculation that has to be made of risk, benefit and need.’

A majority of parents that do not have plans to get their child aged 12 to 17 vaccinated for Covid cite concerns about side effects as the reason why. Around a third are waiting to see if the vaccine is safe, and a quarter are not sure if their children even need the shots

Because of the low risk of severe illness, only a third of parents have said they would get their children vaccinated ‘right away’, with a further third saying they would ‘wait and see’. Five percent said they would ‘only if required,’ while 30 percent said ‘definitely not’

He added, ‘If a drug has a great risk benefit, but it doesn’t have a medical need, why take it? If I’m not in pain, I don’t take a pain medicine for example. That’s a generalization, but for vaccines you have to make sure there is a need.’

A hospital in Connecticut began administering Covid-19 vaccines to children, aged between five to 11, just minutes after the CDC officially signed off on approval. 

The CDC’s decision has caused a storm of controversy with opponents pointing to the fact there is little evidence to suggest vaccinating children is necessary.

The decision means the US becomes one of the first countries in the world to officially approve jabs for this age group, with scientists in Britain warning officials against ‘blindly’ following America and recommending the jab to young children. 

China has reportedly started rolling out its own vaccines to three-year-old children, and Chile is vaccinating children aged six and older. Israel, meanwhile, is expected to follow the US’ lead now the CDC has approved the jabs.

Bahrain approved Sinopharm COVID-19 vaccine for children aged 3-11 from Oct. 27, while on Nov. 2, the Gulf state approved the Pfizer vaccine for emergency use for children aged between 5 and 11 years. 

However, these countries are currently the exception, with countries still weighing up the risks and benefits of the decision. Most are only vaccinating children aged 12 and upwards.

A majority of parents who are hesitant to get their child vaccinated, like Rosselli, fear potential side effects of the vaccine. 

The Week 39 Household Pulse survey, conducted by the U.S. Census Bureau and  published on Wednesday, asked parents of children aged 12 to 17 – who were unsure or definitely did not plan to get their child vaccinated – their reasons for hesitation.

More than two-thirds, 69 percent, reported they were concerned about side-effects, while one in every four parents said they were not sure if their children needed the shot.

A ten year old child high fives Pharmacist Colleen Teevan after he received the Pfizer-BioNTech Covid-19 Vaccine for kids at Hartford Hospital in Hartford, Connecticut

Of 45.7 million respondents, 13 million parents answered they either were ‘unsure’ of, ‘will probably not’ or would ‘definitely not’ getting their child vaccinated.

Those 13 million respondents were then asked why they did not plan on getting their children jabbed.

Nearly one-third reported that they would wait to see whether the vaccine was safe in children that age.

Around 30 percent of parents said they do not trust the government, and three percent say they do not give their child any vaccines.

Among vaccine-hesitant parents who don’t trust the government, California has the highest share at 71 percent 

Many of these parents also fall within the 69 percent of parents who are concerned about the jab’s side-effects and 24 percent who are not sure if their children need the shot. 

The most serious side effect that can strike children is myocarditis, heart inflammation, a rare condition which is usually minor but can result in death in more serious cases.

However, such a condition has only been reported in patients who received the Johnson & Johnson or AstraZeneca shots.  

In Britain, scientists have warned against officials ‘blindly’ recommending the jabs to young children without weighing up the risks ‘extremely carefully’.

Children watch as Pharmacist Colleen Teevan reconstitutes the Pfizer-BioNTech Covid-19 Vaccine for kids before administering it to six children waiting to be among the first 5-11 years olds in the US to receive the newly approved vaccine at Hartford Hospital in Hartford, Connecticut on November 2, 2021

The caps on the children’s vials will be orange, making them easily recognizable compared to the purple caps on the vials for older groups. Pictured: A vial  of the new children’s dose of the Pfizer-BioNTech Covid-19 vaccine, seen at Hartford Hospital in Hartford on Tuesday

Professor David Livermore, a medical microbiologist at the University of East Anglia told the MailOnline last week: ‘Vaccinating children to protect adults via herd immunity is ethically dubious and is scientifically weak.’

There are also still fears about myocarditis, a form of heart inflammation detected in children, mostly boys, in around one in 10,000 cases after vaccination.

Critics say children are better off catching Covid and getting protection naturally because the risk of being admitted to ICU is about one in 500,000.

There are signs that natural immunity in British youngsters is already slowing the epidemic. But some studies have suggested myocarditis is even more common after Covid infection itself, which complicates the matter further.

While most cases of myocarditis after the Covid jab are mild and treatable, the UK Government’s scientific advisers say the long-term effects of the inflammation is not understood.

Data used to justify the FDA panel’s decision showed nearly 180 children would be expected to suffer from myocarditis for every death the vaccine would prevent if the rollout went ahead.

But the side effect would not be expected to cause any deaths.

The rollout would stop over 200 hospitalisations and a handful of deaths over a six-month period, by comparison.

And the data showed it could stop tens of thousands of infections in the same time

Stickers for children are seen ahead of full approval from the CDC for children to receive the Pfizer-BioNTech Covid-19 vaccine at Hartford Hospital in Hartford, Connecticut on November 2, 2021

The CDC had convened a panel of independent scientists on Tuesday to review the available data on the status of the outbreak in children, the effectiveness of Pfizer’s vaccine, and its possible side effects during a day of live-streamed discussions.

The panel unanimously recommended the vaccine, and the CDC then endorsed that recommendation.

The main concern was the risk of myocarditis, an inflammation of the heart muscle, detected in adolescents and young adults (mostly males) after vaccination with the Pfizer or Moderna shots.

Health authorities have confirmed nearly 880 cases in people under 30 years of age, of which approximately 830 required hospitalization.

Nine deaths are suspected to have been related to myocarditis after the vaccine.

But of six cases so far reviewed, vaccine-related myocarditis was ultimately not identified as the cause of death, pediatric cardiologist Dr. Matthew Oster said in a presentation.

‘I’m much more worried about what would happen to their child if they get Covid, for patients who don’t have heart disease, than I am if they were to get this vaccine,’ he added. 

The FDA’s Vaccines and Related Biological Products Advisory Committee voted 17-0-1 that benefits of the vaccine for kids aged five to 11 outweigh the potential risks.

One member of the FDA advisory panel abstained from a vote on recommending the shot to kids last week because he said there is not enough evidence that all children need the shot. 

Dr Michael Kurilla (pictured) was the only member to abstain  in the FDA’s advisory committee vote of 17-0-1 to recommend approval of COVID-19 vaccines in children ages five to 11

Dr Michael Kurilla, the director of the Division of Clinical Innovation, at the National Institutes of Health’s (NIH) National Center for Advancing Translational Sciences, who was the only member to not vote ‘yes’, told DailyMail.com there were several reasons behind his abstention.  

Kurilla says there are children at high-risk of severe Covid due to underlying conditions who would benefit from the shot, but he’s not sure if this applies to all kids in this age group.

Additionally, he said that kids who have been infected with Covid in the past already likely have immunity because of it. 

Kurilla added current data does not suggest the vaccine’s protection will last long enough and he is worried that antibodies will wane in children as has been seen in adults. 

The government was well ahead of the decision, procuring enough doses for the children in the 5-11 age group and beginning to ship them across the country.

‘Today, we have reached a turning point in our battle against Covid-19,’ President Joe Biden said in a statement released by the White House.

Vaccinating younger children will ‘allow parents to end months of anxious worrying about their kids, and reduce the extent to which children spread the virus to others. It is a major step forward for our nation in our fight to defeat the virus,’ the president continued.

A mother holds her childs hand as she prepares to receive the Pfizer-BioNTech Covid-19 Vaccine for kids 5-11 at Hartford Hospital in Hartford, Connecticut on November 2, 2021

The government has already secured enough vaccine for every child in America, he said, adding that over the weekend officials began the process of packing and shipping millions of doses.

‘The program will ramp up over the coming days, and (be) fully up and running during the week of November 8,’ he said.

The vaccine will still be given in two injections, three weeks apart. The dosage has been adjusted to 10 micrograms per injection, compared to 30 micrograms for the older age groups.

The caps on the children’s vials will be orange, making them easily recognizable compared to the purple caps on the vials for older groups.

‘As a mom, I encourage parents with questions to talk to their pediatrician, school nurse or local pharmacist to learn more about the vaccine and the importance of getting their children vaccinated,’ CDC director Rochelle Walensky said in a statement.  

The expected benefits of vaccinating children also include fewer school closures, and a possible reduction in transmission of the epidemic into the general population. 

‘If I had a grandchild, I would certainly get that grandchild vaccinated as soon as possible,’ said Beth Bell, an infectious disease specialist and committee member on the CDC’s independent panel.

‘We have excellent evidence of efficacy and safety. We have a favorable risk benefit analysis.’   

What are other countries doing about Covid-19 vaccinations for children 

The United States is set to roll out Pfizer Inc and BioNTech SE COVID-19 vaccines for children aged 5 to 11 this week and the shots could be administered as soon as Wednesday.

A panel of outside experts is due to meet on Tuesday to vote on how broadly the shot should be recommended in the age group by the U.S. Centers for Disease Control and Prevention (CDC). The vaccine was authorized by the U.S. Food and Drug Administration in the age group on Friday.

But with many parts of the world still awaiting doses for more vulnerable people, the World Health Organisation has urged countries and companies that control the global supply of the vaccines to prioritize supply to COVAX.

The following is a list of some countries that have approved or are considering vaccinating children:

EU COUNTRIES

  • On Oct. 18, the EU’s medicines regulator said it had started evaluating the use of Pfizer and BioNTech’s COVID-19 vaccine in 5 to 11-year-old children.
  • In June, Denmark said it would offer COVID-19 shots to children aged 12-15 to boost its overall immunity against the virus.
  • France has started vaccinating those from 12 years upwards, provided they have parental consent.
  • Germany in August agreed to make vaccination available to all children aged 12-17.
  • Austria has started vaccinating children aged 12-15.
  • Estonia could start vaccinating teenagers by the autumn, public broadcaster ERR reported, citing the head of the government’s COVID-19 council.
  • Hungary started vaccinating 16 to 18-year-olds in mid-May, according to Xinhua news agency.
  • Italy on May 31 approved extending the use of Pfizer’s vaccine to 12-15 year olds. On July 28, it also endorsed the use of Moderna’s vaccine for 12-17 aged children.
  • Lithuania’s prime minister said the country could start vaccinating children from age 12 in June, news site Delfi reported.
  • Spain begun vaccinating children between 12 and 17 years old around two weeks before the academic year in September, the health minister said.
  • Swedish PM says children aged 12-15 will be offered COVID vaccine later this autumn.
  • Greece in July said children aged 12-15 could be vaccinated against COVID-19 with Pfizer/BioNTech and Moderna shots.
  • Finland’s capital Helsinki in June said it will begin giving COVID-19 vaccines to children aged 12 to 15 who are at risk of contracting a severe coronavirus infection.
  • On July 27, Ireland lowered the age for COVID-19 vaccination to 12 years.
  • Poland started offering COVID-19 vaccines to children of ages 12-15.

EUROPE (NON-EU)

  • On Oct. 19, UK said it will open up COVID vaccine booking service to those aged 12-15.
  • Switzerland approved on June 4 vaccinating 12 to 15-year-olds with Pfizer’s shot, while Moderna’s shot was approved in August for the age group.
  • In September, Norway started to offer one dose of Pfizer and BioNTech COVID-19 vaccine to children aged 12 to 15

MIDDLE EAST

  • In August, Israel began offering a COVID-19 booster to children as young as 12.
  • The United Arab Emirates said in August rolled out China’s Sinopharm vaccine to children aged 3-17. On Nov.1, UAE approved Pfizer-BioNtech shot for children aged 5-11 for emergency use.
  • Bahrain approved Sinopharm COVID-19 vaccine for children aged 3-11 from Oct. 27, while on Nov. 2, the Gulf state approved the Pfizer vaccine for emergency use for children aged between 5 and 11 years.

ASIA-PACIFIC

  • Indonesia on Nov. 1 authorised China’s Sinovac vaccine for children aged 6 and above.
  • Malaysia on Oct. 29 said it would procure the Pfizer/BioNTech vaccine for children aged 5 to 11, following a U.S. expert panel’s recommendation
  • Vietnam will begin inoculating children aged 16 and 17 with parental consent from next month using the Pfizer-BioNTech vaccine.
  • An advisory committee to the Indian regulator recommended emergency use of Bharat Biotech’s COVID-19 shot in the 2 to 18 age-group. The regulator’s nod is awaited.
  • New Zealand’s medicines regulator in June provisionally approved use of Pfizer’s vaccine for 12-15 year olds.
  • Australia said on Sept. 12 it will expand its COVID-19 vaccination drive to include around one million children aged 12-15.
  • China on June 5 approved emergency use of Sinovac’s vaccine for those between three and 17.
  • Hong Kong said on June 3 it would open its vaccine scheme to children over the age of 12.
  • Singapore opened up its vaccination programme to adolescents aged 12-18 from June 1.
  • Japan on May 28 approved the use of Pfizer’s vaccine for those aged 12 and above.
  • The Philippines on May 26 decided to allow the Pfizer-BioNTech’s vaccine for emergency use in children aged 12-15.
  • Jordan in July begun vaccinating children aged 12 years and older against COVID-19.

AMERICAS

  • The COVID-19 vaccine by Pfizer-BioNTech will be the only one used in Mexico for at-risk children aged 12-17.
  • Brazil on June 11 approved use of Pfizer’s vaccine for children over 12.
  • On Sept. 6, Chile approved the COVID-19 vaccine produced by China’s Sinovac Biotech Ltd for use in children over 6 years of age.
  • U.S. FDA has authorized the Pfizer vaccine for children aged 5 to 11 years. CDC Director Rochelle Walensky must make her recommendations before it can be rolled out.
  • Canada in early May approved use of Pfizer’s vaccine for use in children aged 12-15 but the decision for children between 5 an 11 years is not likely to come before mid- to end-November.
  • Cuba’s vaccination campaign includes children as young as two.
  • On Sept. 13, El Salvador cleared the use of COVID-19 vaccine in 6 to 11-year-old children. (https://bit.ly/30RiKe7)
  • Argentina is vaccinating children as young as three with Sinopharm COVID-19 vaccine. (https://bit.ly/3miSiCD)
  • Ecuador’s vaccination includes kids as young as six with the China’s Sinovac vaccine
  • Columbia is offering Pfizer, AstraZenenca, Moderna, Sinopharm and J&J’s COVID-19 vaccines for children 12 years and above
  • Costa Rica is vaccinating 12 years and above

AFRICA

  • South Africa will start vaccinating children between the ages of 12 and 17 next week using the Pfizer vaccine

Reporting by Reuters 

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Prior poor mental health linked with higher rates of COVID- study

Several studies have shown that the pandemic took a devastating toll on people’s mental health and impacted other psychiatric conditions, but a novel study looked at things from a different direction.
 The investigation, conducted by Yale School of Public Health and published in the American Journal of Preventative Medicine, looked at US nationwide levels of mental health to establish that those with poor mental health prior to the pandemic have a greater likelihood of developing a COVID-19 infection. 

Researchers used aggregated data from a survey conducted across 2,839 counties to conclude that between 2010 and 2019, a total of 2,172 counties (77%) experienced significant increases in the average number of poor mental health days, including depression, stress, and problems with emotions. Further research revealed that higher days of poor mental health in 2019 had a robust association with the rate of COVID-19 infections in 2020, leading researchers to believe that the pandemic did not cause new mental health problems, but rather revealed previously ignored issues. 

Analysis revealed that poorer mental health days and COVID rates were driven by a few states– Arizona, Montana, and Nevada.  

Mental health [illustrative] PIXABAY

Lead investigator Yusuf Ransome expressed hope that the study will encourage conversation about the urgency of mental health care. 

“We call for policies that strengthen surveillance systems to better capture a range of mental health outcomes in the population, address social inequalities that give rise to poor mental health, and funding to create, sustain, and equitably distribute mental health resources, including wellness care centers across US communities,” he said. 

Ransome added that the idea for the study was inspired by the height of the pandemic. 

“Only a handful of studies examining small fragments of the population had considered the possibility that poor mental health could be contributing to a higher burden of infection rather than vice versa. We wanted to examine whether these relationships also existed in the general population, address the lack of studies with an ecological-level focus, and produce evidence to strengthen calls for interventions.”



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Mecklenburg County to lift mask mandate after new conditions are met – WSOC TV

CHARLOTTE — Mecklenburg County’s indoor mask mandate will be automatically lifted when the average percent positive rate for COVID-19 is below 5% for one week, commissioners unanimously approved Wednesday night.

“I hear the frustration,” Commissioner Leigh Altman said. “I read the emails. I entreat this community to reach down deep and understand that we are following the metrics. This is about listening to the science, the data and doing our best to navigate through this.”

Mecklenburg County Health Director Gibbie Harris clarified that the rate must be 4.99% or lower for seven days. A vote or a meeting is not required to lift the mask mandate.

Harris said that she supports the decision to lift the mask mandate under that condition.

She said when the county reaches that goal, it will indicate the county has moved in the right direction and it is an opportunity to give the public a break.

The current weekly average is 7.1%, but questions have been raised about the metrics being used.

There’s a difference between county and state percent of positivity rate, which has created some confusion. The metric is important because it’s the one Mecklenburg County is using to decide what to do about the indoor mask mandate.

Officials with the health department said they’ve noticed that the state is reporting lower rates than what NCDHHS is.

The county health department told Channel 9 it calculates the positivity rate by dividing the number of positive tests collected on a given day by the total number of tests taken, however, the figures do not match the state’s numbers.

For example, the county is reporting a 7.1% positivity rate, as of Friday. At the same time, the state reported 5.8%.

Mecklenburg County Deputy Health Director Dr. Raynard Washington visited Channel 9′s studios on Wednesday morning and explained that there is an issue happening with the data coming back from the lab and that they are working with the state to sort out the discrepancy.

The countywide mask mandate was implemented at the beginning of September due to the rise in COVID-19 cases.

The mandate requires face coverings to be worn in any indoor public place, business or establishment within the city of Charlotte and the unincorporated areas of Mecklenburg County, regardless of vaccination status. The requirement applies to anyone age 4 or older.

(WATCH BELOW: Dr. Raynard Washington explains Meck County’s plan to roll out vaccines for kids ages 5-11)



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Plant in traditional Samoa medicine could be as effective as ibuprofen, study shows | Samoa

Leaves from a plant which can be found “in back yards across Samoa” could be as effective as ibuprofen in lowering inflammation and could even be used to treat illnesses such as Parkinson’s and cancer, a new study has found.

For centuries, the leaves of the psychotria insularum plant, known locally in Samoa as matalafi, have been used in traditional medicine to treat inflammation associated with fever, body aches, swellings, elephantiasis, and respiratory infections.

“I was sceptical at first, when researching” said Seeseei Molimau-Samasoni, the study’s author and the manager of the plants and postharvest technologies division at the Scientific Research Organisation of Samoa.

“There was a lot of superstition around this plant particularly, even in traditional medicine, but I was keen to find out if I could provide scientific merit to the traditional medicines of the Samoan people,” she said.

“We can now highlight not only its potential as an anti-inflammatory agent but also its potential as a treatment for cancer, neurodegenerative diseases, diabetes, cardiovascular diseases as well as Covid-19.”

Molimau-Samasoni and her colleagues’ findings have been peer-reviewed and are due to be published in the Proceedings of the National Academy of Sciences of the United States of America.

“The leaves are chopped up and the juice is squeezed out. Traditional healers use that juice as drink for their patients. Sometimes they also use the leaves to rub on a person who is unwell or apply it to a wound that needs healing,” said Molimau-Samasoni, adding that traditional medicine runs in her family.

“I grew up with my maternal grandmother and she was a traditional healer,” she said. “When she passed away, she passed on her treatments to me so I’m now kind of a traditional healer myself.”

Molimau-Samasoni acknowledged there was a lot of scepticism and hesitancy shown toward traditional medicine.

“The challenge between modern medicine and traditional medicine is the instances where people focus on just one type of medicine before seeking the other, so a case where people seek anti-cancer treatments from traditional healers but then present to the hospital later on with stage four cancer, when it’s too late for modern medicine to do anything” she said.

“And so I know many people think traditional medicine is just people mashing leaves together and that people are taking it just for the placebo effect, but you need to remember that traditional medicine has made significant contributions to the world of modern pharmaceuticals, examples of which include aspirin.”

As for matalafi, Molimau-Samasoni said it would likely be years before it is available as an approved medicine but said she also believes it is just the beginning, not only for matalafi, but for broader research into how Samoa’s traditional medicines could be used today.

“I believe we’ve just started to unravel the potential of matalafi. But there’s also honestly hundreds of other traditional medicines here in Samoa to research,” she said.

“We now have a laboratory dedicated to anti-microbial benefits in traditional medicines, a laboratory looking into anti-diabetes activity in traditional medicines and a laboratory looking into anti-cancer activity in traditional medicines. We are only just getting started.”

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Oregon reports 64 more COVID-19 related deaths, 10 from C.O.; OHA adding 100s missed months ago

(Update: 10 of newly reported deaths from C. Oregon; weekly report shows cases rise, deaths, hospitalizations decline)

PORTLAND, Ore. (KTVZ) — There are 64 newly reported COVID-19 related deaths in Oregon, raising the state’s death toll to 4,469, the Oregon Health Authority said Wednesday as it works to clear more than 500 earlier deaths not initially reported due to a computer issue.

Central Oregon health departments said the newly reported deaths included 10 from the region — eight from Deschutes County, where the toll has reached 136, and two from Jefferson County, bringing its total to 60 deaths.

OHA also reported 1,128 new confirmed and presumptive cases of COVID-19 as of 12:01 a.m. today, bringing the state total to 369,815.

Reminder: State health officials to add more than 500 COVID-19 deaths due to technical error

Over the coming weeks, OHA will report approximately 550 deaths among people who died with COVID-19, but whose deaths only became recently known to state epidemiologists due to a technical computer error. 

This will result in higher death totals as the backlog is resolved.

More details can be found here.

Link to Wednesday’s Oregon Health Authority media availability

Wednesday afternoon, Dr. Dean Sidelinger, the state epidemiologist, and Dr. Kristen Dillon, senior advisor with Oregon Health Authority’s COVID Response and Recovery Unit, answered media questions concerning the newly authorized vaccine for children ages five through 11.

Watch the video to see what they had to say.

COVID-19 weekly cases increase, deaths and hospitalizations decline

Oregon Health Authority’s COVID-19 Weekly Report, released Wednesday, shows an increase in daily cases and decreases in hospitalizations and deaths.

OHA reported 7,877 new cases of COVID-19 during the week of Monday, Oct. 25 through Sunday, Oct. 31. That represents a 2.2% increase from the previous week and the first increase after eight consecutive weeks of declining counts.

The incidence of reported COVID-19 cases was higher in Oregon counties with population vaccination rates less than 50%.

There were 313 new COVID-19 hospitalizations, down from 415 last week, marking the lowest number of hospitalizations since the week of July 26 – Aug. 1.

There were 82 reported COVID-19 related deaths, down from 110 reported the previous week.

There were 130,325 tests for COVID-19 for the week of Oct. 24 through Oct. 30. The percentage of positive tests was 7.4%, unchanged from the previous week.

Wednesday’s COVID-19 Weekly Outbreak Report shows 87 active COVID-19 outbreaks in senior living communities and congregate living settings, with three or more confirmed cases and one or more COVID-19 related deaths.

COVID-19 hospitalizations

The number of hospitalized patients with COVID-19 across Oregon is 527, which is 10 fewer than Tuesday. There are 116 COVID-19 patients in intensive care unit (ICU) beds, which means there has been no change from Tuesday.

There are 53 available adult ICU beds out of 686 total (8% availability) and 255 available adult non-ICU beds out of 4,127 (6% availability). 

11/3/2021 Available Beds (and Percentage of Staffed Beds Available)
  Statewide Region 1 Region 2 Region 3 Region 5 Region 6 Region 7 Region 9
Adult ICU beds available 53(8%) 22(6%) 5(6%) 12(13%) 2(3%) 1(10%) 4(8%) 7(27%)
Adult non-ICU beds available 255(6%) 30(2%) 17(3%) 92(16%) 27(6%) 1(2%) 36(9%) 52(45%)

St. Charles Bend reported 64 COVID-19 patients as of early Wednesday, five of whom were in the ICU, with four on ventilators. None of the five ICU patients were fully vaccinated, the hospital said, while 46 of the 64 patients were not fully vaccinated.

The total number of patients in hospital beds may fluctuate between report times. The numbers do not reflect admissions per day, nor the length of hospital stay. Staffing limitations are not captured in this data and may further limit bed capacity.

Note: Please do not visit an emergency department for COVID-19 testing, unless you require emergency care for your symptoms.

Emergency departments in Oregon are under significant strain. You can find a test here.

If you have a medical condition that doesn’t require emergency care, contact your provider. An urgent care center may also help you get the care you need and will save emergency departments from added strain.

More information about hospital capacity can be found here.

Vaccinations in Oregon

OHA reported Wednesday that 17,000 new doses of COVID-19 vaccinations were added to the state immunization registry on Tuesday. Of that total, 1,115 were initial doses, 815 were second doses and 8,000 were third doses and booster doses. The remaining 7,013 were administered on previous days but were entered into the vaccine registry on Tuesday.

The seven-day running average is now 17,000 doses per day.

Oregon has now administered 3,317,989 doses of Pfizer Comirnaty, 2,030,215 doses of Moderna and 229,962 doses of Johnson & Johnson COVID-19 vaccines.

As of Wednesday, 2,824,604 people have had at least one dose of a COVID-19 vaccine and 2,618,574 people have completed a COVID-19 vaccine series.

These data are preliminary and subject to change.

Updated vaccination data are provided on Oregon’s COVID-19 data dashboards and have been updated Wednesday.

Cases and COVID-19 deaths

The new confirmed and presumptive COVID-19 cases reported Wednesday are in the following counties: Baker (6), Benton (18), Clackamas (87), Clatsop (5), Columbia (13), Coos (26), Crook (13), Curry (5), Deschutes (113), Douglas (42), Gilliam (1), Grant (5), Hood River (5), Jackson (77), Jefferson (26), Josephine (39), Klamath (22), Lake (5), Lane (42), Lincoln (15), Linn (68), Malheur (18), Marion (91), Morrow (1), Multnomah (131), Polk (38),Tillamook (10), Umatilla (30), Union (3), Wallowa (3), Wasco (11), Washington (128) and Yamhill (31).

Note: More information about the cases and deaths will be provided in an updated news release.

Learn more about COVID-19 vaccinations  

To learn more about the COVID-19 vaccine situation in Oregon, visit OHA’s web page (English or Spanish), which has a breakdown of distribution and other information.

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Drop in US life expectancy second highest among wealthy countries: study

Life expectancy in the United States saw the second highest drop among wealthy countries during the pandemic, a new study reveals, NBC reported.

The BMJ, previously known as the British Medical Journal, published a study on Wednesday that examined what life expectancy in 2020 would have been after analyzing historical trends between 2005 and 2019, and compared that to observed life expectancy in 2020, according to the network.

Studying data from 37 countries, the study found that U.S. life expectancy declined close to 2.3 years for men and over 1.6 years for women. The lead author, Dr. Nazrul Islam, told NBC News that the deaths of young people fueled the drop in life expectancy.

“That’s really, really sobering,” Islam said.

The only country that fared worse than the U.S. was Russia. The study found that Lithuania and Bulgaria also suffered large declines in life expectancy. In total, 31 countries saw a drop in life expectancy out of the 37 analyzed, according to NBC News.

Three countries saw an increase in life expectancy — Norway, Taiwan and New Zealand. Three other countries — South Korea, Denmark and Iceland — saw little change before and after 2020. 

The study noted, however, that between 2005 and 2019, all 37 countries saw life expectancy going up.

The sobering details come as the U.S. early last month surpassed the grim milestone of 700,000 COVID-19 deaths. More than five million people have died worldwide from the coronavirus. 

Despite the fact that COVID-19 vaccines are widely accessible in the U.S., pockets of the United States remain unvaccinated and conversations about potential herd immunity earlier this year have shifted to an acknowledgment that people will likely need to learn how to live with the virus, similar to the flu.



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